Carbohydrate-Binding Module Family 50

Known ActivitiesModules of approx. 50 residues found attached to various enzymes from families GH18, GH19, GH23, GH24, GH25 and GH73, i.e. enzymes cleaving either chitin or peptidoglycan. Binding to chitopentaose demonstrated in the case of Pteris ryukyuensis chitinase A [Ohnuma T et al. (2008) J. Biol. Chem. 283:5178-87 (PMID: 18083709)]. CBM50 modules are also found in a multitude of other enzymes targeting the petidoglycan such as peptidases and amidases. These enzymes are not reported in the list below.
NoteAlso known as LysM domains
External resourcesInterPro; PFAM;
Statistics GenBank accession (3148); Uniprot accession (1452); PDB accession (2); 3D entries (3); cryst (1)
All (5085) Archaea (3) Bacteria (4849) Eukaryota (149) Viruses (80) unclassified (4) Structure (3 - 1 cryst) Characterized (2)
Bacteria
Protein Name EC#OrganismGenBankUniprotPDB/3D
 b0211 (MltD)   Escherichia coli K-12 MG1655 AAB08633.1
AAC73316.1
CAU96090.1
NP_414747.1
P23931 1E0G[A]
 lectin (MSMEG_3662)   Mycobacterium smegmatis str. MC2 155 ABK70862.1 A0QYH7 cryst
Eukaryota
Protein Name EC#OrganismGenBankUniprotPDB/3D
 lectin (MGG_03307)   Magnaporthe grisea 70-15 EDK00177.1   2L9Y[A]




Last update: 2012-01-31 © Copyright 1998-2012
AFMB - CNRS - Universités Aix-Marseille I & II