Carbohydrate-Binding Module Family 50

Activities in FamilyModules of approx. 50 residues found attached to various enzymes from families GH18, GH19, GH23, GH24, GH25 and GH73, i.e. enzymes cleaving either chitin or peptidoglycan. Binding to chitopentaose demonstrated in the case of Pteris ryukyuensis chitinase A [Ohnuma T et al. (2008) J. Biol. Chem. 283:5178-87 (PMID: 18083709)]. CBM50 modules are also found in a multitude of other enzymes targeting the petidoglycan such as peptidases and amidases. These enzymes are not reported in the list below.
NoteAlso known as LysM domains
External resourcesCAZypedia;
Statistics GenBank accession (121103); Uniprot accession (16); PDB accession (39); 3D entries (28); cryst (0)
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Viruses
Protein Name EC#OrganismGenBank UniprotPDB/3D
 EauM23_00028   Exiguobacterium phage vB_EauM-23 QBL97921.1    
 immuto136C_236   Flavobacterium phage vB_FspM_immuto_13-6C QQO92392.1    
 uvFWCGRAMDCOMC403_019   Freshwater phage uvFW-CGR-AMD-COM-C403 ANH49283.1    
 N-acetylmuramoyl-L-alanine amidase   Gaunavirus SRT01hs QHJ75885.1    
 cell wall-binding protein   Geobacillus phage GR1 UDY80672.1    
 N-acetylmuramoyl-L-alanine amidase   Geobacillus phage GR1 UDY80750.1    
 N-acetylmuramoyl-L-alanine amidase   Geobacillus phage GR1 UDY80750.1    
 endolysin   Geobacillus phage TP-84 AQY55126.1    
 endolysin   Geobacillus phage TP-84 AQY55126.1    
 endolysin   Geobacillus phage TP-84 AQY55126.1    
 PK21_gp28   Geobacillus phage vB_GthS_PK2.1 UYL93864.1    
 PK21_gp28   Geobacillus phage vB_GthS_PK2.1 UYL93864.1    
 PK52_gp19   Geobacillus phage vB_GthS_PK5.2 UYL94146.1    
 PK52_gp19   Geobacillus phage vB_GthS_PK5.2 UYL94146.1    
 VOLT_14   Glutamicibacter phage Voltaire CAH1191492.1    
 NJHLHPIG_00126   Klebsiella phage 020009 CAD5240614.1    
 NBNDMPCG_00023   Klebsiella phage 020009 CAD5240470.1    
 IPGJFKPH_00017 (XkdP)   Klebsiella phage 020009 CAD5241135.1    
 KBDEFBCI_00123   Klebsiella phage 020009 CAD5240761.1    
 conserved uncharacterised protein   Klebsiella phage 05F01 BBK09227.1    
 OJNDCHOG_01460   Klebsiella phage 150040 UXD79556.1    
 ayl_00222   Klebsiella phage AYL WKN59805.1    
 IANJMKHF_00458   Klebsiella phage CPRSA UQJ95363.1    
 ALHIDCOG_00424   Klebsiella phage CPRSB UQJ95811.1    
 iPHageKPN11i_00195   Klebsiella phage iPHaGe-KPN-11i WOL25537.1    
 iPHageKPN12i_00105   Klebsiella phage iPHaGe-KPN-12i WOL25174.1    
 K751_00066   Klebsiella phage K751 UPW36072.1    
 KOX11_77   Klebsiella phage KMI10 QEG10760.1    
 KOX8_85   Klebsiella phage KMI7 QEG10251.1    
 KOX10_86   Klebsiella phage KMI9 QEG10517.1    
 OOGAAMIP_00156   Klebsiella phage Kp11 WPJ20913.1    
 PMMJPKLI_00136   Klebsiella phage KP13MC5-1 UYL05676.1    
 EKPIEFBL_00084   Klebsiella phage KP15 CAD5241418.1    
 GCLPFEGH_00147   Klebsiella phage KP15 CAD5242177.1    
 POFPNCPI_00068   Klebsiella phage KP15 CAD5241425.1    
 INMBNBLA_00231 (XkdP)   Klebsiella phage KP15 CAD5242828.1    
 EHPPICDA_00272   Klebsiella phage KP15 CAD5243115.1    
 FPLNFCPP_00155   Klebsiella phage KP1LMA WVX87149.1    
 KP27_024   Klebsiella phage KP27 AEX26500.1    
 PLAPEKGO_00071   Klebsiella phage KP6 WVX98370.1    
 ORF   Klebsiella phage KpF2 WMX18227.1    
 phKl35c1_85   Klebsiella phage Kpn35c1 UJP30712.1    
 KPN8_183   Klebsiella phage KPN8 UVD41974.1    
 ORF   Klebsiella phage Kp_GWPR59 WAW44495.1    
 CPT_Magnus_121   Klebsiella phage Magnus QEG08000.1    
 CPT_Matisse18   Klebsiella phage Matisse AKU44322.1    
 CPT_May_115   Klebsiella phage May AUG88029.1    
 CPT_Menlow_121   Klebsiella phage Menlow AUG87822.1    
 CPT_Miro18   Klebsiella phage Miro AKU44602.1    
 PKP2_75   Klebsiella phage P-KP2 QIW86127.1    
 GHCGIGKI_00790   Klebsiella phage P01 WOZ56607.1    
 ORF   Klebsiella phage P60_7 WNA08990.1    
 ORF   Klebsiella phage phiKp_1 BEH83605.1    
 ORF   Klebsiella phage phiKp_10 BEH85271.1    
 ORF   Klebsiella phage phiKp_11 BEH85686.1    
 ORF   Klebsiella phage phiKp_12 BEH85972.1    
 ORF   Klebsiella phage phiKp_13 BEH86157.1    
 ORF   Klebsiella phage phiKp_15 BEH86391.1    
 ORF   Klebsiella phage phiKp_16 BEH86695.1    
 ORF   Klebsiella phage phiKp_17 BEH86969.1    
 ORF   Klebsiella phage phiKp_18 BEH87243.1    
 ORF   Klebsiella phage phiKp_19 BEH87487.1    
 ORF   Klebsiella phage phiKp_20 BEH87879.1    
 ORF   Klebsiella phage phiKp_23 BEH88952.1    
 ORF   Klebsiella phage phiKp_26 BEH89189.1    
 ORF   Klebsiella phage phiKp_3 BEH83726.1    
 ORF   Klebsiella phage phiKp_4 BEH84121.1    
 ORF   Klebsiella phage phiKp_5 BEH84398.1    
 ORF   Klebsiella phage phiKp_8 BEH84881.1    
 ORF   Klebsiella phage phiKp_9 BEH84966.1    
 phiKPNS3_00026   Klebsiella phage phi_KPN_S3 WDQ26293.1    
 Phage protein   Klebsiella phage PMBT1 SCO64595.1    
 KEKKGBKC_00193   Klebsiella phage pR7_1 UZO33462.1    
 2DI_00200   Klebsiella phage PSKm2DI UUG67081.1    
 4DII_00201   Klebsiella phage PSKm4DII UUG67352.1    
 PWKp5_00055   Klebsiella phage PWKp5 UJD04798.1    
 R21_98   Klebsiella phage R2_1 WKC55267.1    
 R41_104   Klebsiella phage R4_1 WKC55552.1    
 R61_238   Klebsiella phage R6_1 WKC55129.1    
 FADJDIKG_00264 (XkdP)   Klebsiella phage vB_KoM-MeTiny CAD6025573.1    
 K41P2_LOCUS196   Klebsiella phage vB_Ko_K41P2 CAK6607478.1    
 peptidoglycan biding protein   Klebsiella phage vB_KpnM-VAC66 QYC51141.1    
 ONPBNFGJ_00032   Klebsiella phage vB_KpnM_05F CAA7537520.1    
 kps110_184   Klebsiella phage vB_KpnM_KpS110 AUV59300.1    
 vBKpnMM1_gp18c   Klebsiella phage vB_KpnM_M1 QQO91417.1    
 peptidoglycan binding protein   Klebsiella phage vB_KpnM_VAC13 QWY13729.1    
 MDA2066_orf202   Klebsiella phage vB_KpnS_MDA2066 WJJ58883.1    
 ORF   Klebsiella virus UPM 2146 QGF20725.1    
 ORF   Lacticaseibacillus phage C4.1 WBM89667.1    
 ORF   Lacticaseibacillus phage P7.1 WBM89758.1    
 ORF   Lacticaseibacillus phage P7.1 WBM89758.1    
 ORF   Lacticaseibacillus phage R10.1 WBF77170.1    
 ORF   Lacticaseibacillus phage R23.9 WBF77234.1    
 ORF   Lacticaseibacillus phage R24.1 WBF77306.1    
 ORF   Lacticaseibacillus phage R26.26 WBF77478.1    
 ORF   Lacticaseibacillus phage R29.1 WBF77516.1    
 ORF   Lacticaseibacillus phage R29.1 WBF77516.1    
 ORF   Lacticaseibacillus phage R3.1 WBM89837.1    
 ORF   Lacticaseibacillus phage R3.1 WBM89837.1    
 ORF   Lacticaseibacillus phage R9.1 WBM89963.1    
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