Carbohydrate-Binding Module Family 50

Activities in FamilyModules of approx. 50 residues found attached to various enzymes from families GH18, GH19, GH23, GH24, GH25 and GH73, i.e. enzymes cleaving either chitin or peptidoglycan. Binding to chitopentaose demonstrated in the case of Pteris ryukyuensis chitinase A [Ohnuma T et al. (2008) J. Biol. Chem. 283:5178-87 (PMID: 18083709)]. CBM50 modules are also found in a multitude of other enzymes targeting the petidoglycan such as peptidases and amidases. These enzymes are not reported in the list below.
NoteAlso known as LysM domains
External resourcesCAZypedia;
Statistics GenBank accession (121103); Uniprot accession (16); PDB accession (39); 3D entries (28); cryst (0)
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Viruses
Protein Name EC#OrganismGenBank UniprotPDB/3D
 LysM domain protein   Bacteriophage sp. QHJ77125.1    
 LysM domain protein   Bacteriophage sp. QHJ75994.1    
 ORF   Bacteriophage sp. QHJ77966.1    
 ORF   Bacteriophage sp. QHJ77966.1    
 ORF   Bacteriophage sp. QHJ78298.1    
 LysM domain protein   Bacteriophage sp. QHJ85541.1    
 ORF   Bacteriophage sp. QHJ76532.1    
 ORF   Bacteriophage sp. QHJ84846.1    
 ORF   Bacteriophage sp. QHJ77589.1    
 LysM domain protein   Bacteriophage sp. QHJ84983.1    
 ORF   Bacteriophage sp. QHJ78355.1    
 ORF   Bacteriophage sp. QHJ78355.1    
 ORF   Bacteriophage sp. QHJ84859.1    
 ORF   Bacteriophage sp. QHJ78311.1    
 ORF   Bacteriophage sp. QHJ77112.1    
 ORF   Bacteriophage sp. QHJ82951.1    
 2016_scaffold57_00015   Bacteriophage sp. AFB75734.1    
 2210_scaffold709_00019   Bacteriophage sp. AFB76124.1    
 ORF   Bacteriophage sp. UYL88506.1    
 lysozyme (B103_15)   Beecentumtrevirus B103 CAA67646.1
NP_690649.1
   
 lysozyme (B103_15)   Beecentumtrevirus B103 CAA67646.1
NP_690649.1
   
 peptidoglycan hydrolase (15)   Beecentumtrevirus Nf ACH57083.1    
 peptidoglycan hydrolase (15)   Beecentumtrevirus Nf ACH57083.1    
 BIBE0010001c01_00040   Bifidobacterium phage BigBern1 QIG78226.1    
 BIBE0010001c01_00040   Bifidobacterium phage BigBern1 QIG78226.1    
 BLBA0010001c01_00013   Bifidobacterium phage BlindBasel1 QIG78090.1    
 BLBA0010001c01_00013   Bifidobacterium phage BlindBasel1 QIG78090.1    
 BRUR0010001c01_00007   Bifidobacterium phage BlindUri1 QIG78038.1    
 BRUR0010001c01_00007   Bifidobacterium phage BlindUri1 QIG78038.1    
 PBI_I3_102   Bixzunavirus I3 QWT30376.1    
 ABOUO_22   Brevibacillus phage Abouo AGR47462.1    
 DAVIES_22   Brevibacillus phage Davies AGR47554.1    
 JIMMER1_24   Brevibacillus phage Jimmer1 AGR47269.1    
 JIMMER2_24   Brevibacillus phage Jimmer2 AGR47166.1    
 OSIRIS_27   Brevibacillus phage Osiris ALA07366.1    
 POWDER_27   Brevibacillus phage Powder ALA48037.1    
 PBI_CANTARE_25   Brevibacterium phage Cantare AYQ99245.1    
 lysin   Butyrivibrio phage Idris QHJ73842.1    
 ORF   Butyrivibrio virus Arian QHJ73661.1    
 secreted Lys-M/SCP-PR1 domain protein   Butyrivibrio virus Arian QHJ73619.1    
 ORF   Butyrivibrio virus Bo-Finn QHJ73726.1    
 secreted Lys-M/SCP-PR1 domain protein   Butyrivibrio virus Bo-Finn QHJ73685.1    
 secreted Lys-M/SCP-PR1 domain protein   Butyrivibrio virus Ysbryn QHJ73892.1    
 ORF   Butyrivibrio virus Ysbryn QHJ73933.1    
 ORF   Citrobacter phage IME-CF2 AKR16017.1    
 CPT_Margaery23   Citrobacter phage Margaery ALF01712.1    
 CPT_Maroon_020   Citrobacter phage Maroon AYJ72884.1    
 CPTMiller_0020   Citrobacter phage Miller AIK67956.1    
 ABCD_0021   Citrobacter phage vB_CfrM_CfP1 ANS06110.1    
 LysM   Clostridioides phage CD1801 QVW56620.1    
 LysM   Clostridioides phage CD2301 QVW56662.1    
 JD033_33   Clostridioides phage JD033 QIW86812.1    
 phiC2p21   Clostridioides phage phiC2 ABE99484.1    
 LysM   Clostridioides phage phiCD08011 QVW56690.1    
 portal protein   Clostridioides phage phiCD418 QVW56739.1    
 Semix9P1_phi16   Clostridioides phage phiSemix9P1 ARB07059.1    
 tail length tape measure protein   Clostridium phage Amboise WAK79315.1    
 CDKM15_23   Clostridium phage CDKM15 ANT45166.1    
 CDHM9_18   Clostridium phage CDKM9 ANT45086.1    
 JD032_40   Clostridium phage JD032 QBJ05085.1    
 XkdP protein   Clostridium phage phi CD119 AAX53480.1    
 PHICD48101_20015   Clostridium phage phiCD481-1 CEK40586.1    
 PHICD505_20018   Clostridium phage phiCD505 CEK40643.1    
 PHICD506_20015   Clostridium phage phiCD506 CEK40716.1    
 putatice cell wall hydrolase/LysM protein (Phicdhm11_gp14)   Clostridium phage phiCDHM11 CDL68831.1    
 puative cell wall hydrolase/LysM protein (Phicdhm13_gp14)   Clostridium phage phiCDHM13 CDL65297.1    
 ORF   Clostridium phage phiCDHM14 CDU85301.1    
 ORF   Clostridium phage phiCDHM19 CDW17204.1    
 phiCT453A_47   Clostridium phage phiCT453A AJA42537.1    
 phiCT9441A_60   Clostridium phage phiCT9441A AJA42672.1    
 PHIMMP01_20023   Clostridium phage phiMMP01 CEK40777.1    
 phiMMP02_gp19   Clostridium phage phiMMP02 AFO72080.1    
 PHIMMP03_20023   Clostridium phage phiMMP03 CEK40858.1    
 phiMMP04_gp14   Clostridium phage phiMMP04 AFO72151.1    
 tail protein   Clostridium phage Saumur WAK79555.1    
 endolysin   Clostridium phage Saumur WAK79598.1    
 endolysin   Clostridium phage Saumur WAK79539.1    
 endolysin   Clostridium phage Saumur WAK79539.1    
 endolysin   Clostridium phage Saumur WAK79539.1    
 ORF   Cronobacter phage Dev_CS701 UPW35446.1    
 AKFOPBLP_00020   Cronobacter phage JC03 QVW27242.1    
 EHEKIMEA_00085   Cronobacter phage LPCS28 UNY46968.1    
 BANACH_94   Cronobacter phage vB_CsaD_Banach UGO54477.1    
 GAP161_018   Cronobacter phage vB_CsaM_GAP161 AFC22125.1    
 GAP32_180   Cronobacter phage vB_CsaM_GAP32 GAP-32 AFC21630.1    
 INVICTA_72   Cronobacter phage vB_CsaM_Invicta UGV22842.1    
 B_021   Cronobacter phage vB_CsaM_leB AOG16147.1    
 E_020   Cronobacter phage vB_CsaM_leE AON97029.1    
 N_020   Cronobacter phage vB_CsaM_leN AOG16426.1    
 G_22 (22)   Donellivirus gee AEO93293.1    
 G_185 (185)   Donellivirus gee AEO93445.1    
 G_185 (185)   Donellivirus gee AEO93445.1    
 G_185 (185)   Donellivirus gee AEO93445.1    
 G_23 (23)   Donellivirus gee AEO93294.1    
 LE23_35   Eggerthella phage LE2-3 QXJ36637.1    
 EBPL_00026   Enterobacter phage EBPL QJI53069.1    
 ECF1_0093   Enterobacter phage EC-F1 URP86045.1    
 ECF2_0091   Enterobacter phage EC-F2 URP86319.1    
 ECW1_0093   Enterobacter phage EC-W1 URP85489.1    
 ECW2_0093   Enterobacter phage EC-W2 URP85771.1    
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