Activities in Family	[protein]-3-O-(GlcNAc)-L-Ser/Thr β-N-acetylglucosaminidase (EC 3.2.1.169); Hyaluronidase / hyaluronoglucosaminidase (EC 3.2.1.35); β-N-acetylhexosaminidase (EC 3.2.1.52);
Mechanism	Retaining e
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	carbonyl oxygen of C-2 acetamido group of substrate
Catalytic Proton Donor	Asp
Note	Mechanism shown in Macauley et al. (2005) JBC 280:25313-25322
External resources	CAZypedia;
Commercial Enzyme Provider(s)	PROZOMIX;
Statistics	GenBank accession (3338); Uniprot accession (25); PDB accession (78); 3D entries (10); cryst (0)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
PZB75_08575		Streptomyces sp. AM 4-1-1	WEH33431.1
RPQ07_32575		Streptomyces sp. AM2-3-1	WNO76060.1
RPQ07_24250		Streptomyces sp. AM2-3-1	WNO74527.1
RPQ02_35605		Streptomyces sp. AM8-1-1	WNO68765.1
RPQ02_14165		Streptomyces sp. AM8-1-1	WNO64870.1
CVT30_40320		Streptomyces sp. AMCC400023	UJV45261.1
RI578_34645		Streptomyces sp. BB1-1-1	WND39118.1
K2224_01055		Streptomyces sp. BHT-5-2	QZL06549.1
K2224_36400		Streptomyces sp. BHT-5-2	QZL08556.1
OIM89_10960		Streptomyces sp. BI87	UYX94224.1
OIM89_21130		Streptomyces sp. BI87	UYX96069.1
WAB15_15190		Streptomyces sp. BP-8	WXK81532.1
WAB15_32380		Streptomyces sp. BP-8	WXK80331.1
QIY60_18480		Streptomyces sp. BPTC-684	WHM38700.1
JIX56_40350		Streptomyces sp. CA-210063	UUU35607.1
JHY03_21890		Streptomyces sp. CA-256286	QTA32045.1
N7925_24490		Streptomyces sp. CA-278952	WDG31258.1
HYC88_24295		Streptomyces sp. CB00271	QNQ36481.1
C2142_11665		Streptomyces sp. CB01881	AUY49489.1
HXS80_24710		Streptomyces sp. CB04723	QLG36520.1
NI25_36120		Streptomyces sp. CCM_MD2014	AIV38295.1
ABE83_24825		Streptomyces sp. CFMR 7	ALC29914.1
RJD14_07765		Streptomyces sp. CGMCC 4.1456	WNF62492.1
VJ737_09255		Streptomyces sp. CGMCC 4.1772	WRT97856.1
VJ737_27440		Streptomyces sp. CGMCC 4.1772	WRU01181.1
PET44_11680		Streptomyces sp. CGMCC 4.1796	WBY20234.1
SJH97_11170		Streptomyces sp. CL7	WPP29861.1
CXR04_05305		Streptomyces sp. CMB-StM0423	AUH39737.1
CXR04_24860		Streptomyces sp. CMB-StM0423	AUH42975.1
AA958_09820		Streptomyces sp. CNQ-509	AKH82480.1
AA958_28465		Streptomyces sp. CNQ-509	AKH85523.1
NNW99_07260		Streptomyces sp. CRCS-T-1	UUA12952.1
NNW99_24970		Streptomyces sp. CRCS-T-1	UUA16197.1
NNW98_25085		Streptomyces sp. CRLD-Y-1	UUA08592.1
NNW98_07260		Streptomyces sp. CRLD-Y-1	UUA05326.1
V8690_14550		Streptomyces sp. DG1A-41	WWT95576.1
V8690_33370		Streptomyces sp. DG1A-41	WWT98778.1
WID27_26105		Streptomyces sp. f41	WYH78654.1
WJM95_10845		Streptomyces sp. f51	WYH82904.1
B1K54_13385		Streptomyces sp. fd1-xmd	AQT72538.1
KK483_32690		Streptomyces sp. FIT100	UUN31577.1
KK483_11395		Streptomyces sp. FIT100	UUN26943.1
SFR_5038		Streptomyces sp. FR-008	ALM41653.1
SFR_2645		Streptomyces sp. FR-008	ALM39260.1
Q7C01_32350		Streptomyces sp. FXY-T5	WMD08784.1
KNZ81_11150		Streptomyces sp. G11C(2021)	UUD68160.1
KNZ81_21505		Streptomyces sp. G11C(2021)	UUD69998.1
NUT86_14805		Streptomyces sp. G7(2002)	WDT55233.1
B591_21462		Streptomyces sp. GBA 94-10 4N24	ESP97450.1
B591_11160		Streptomyces sp. GBA 94-10 4N24	ESQ00272.1
GR131_08765		Streptomyces sp. GF20	QHC15522.1
GR131_19595		Streptomyces sp. GF20	QHC17468.1
KQY30_23870		Streptomyces sp. GMY02	QXE36798.1
C1703_13125		Streptomyces sp. Go-475	AXE85948.1
LUX31_21945		Streptomyces sp. GQFP	UIX32483.1
GR130_30360		Streptomyces sp. GS7	QHC27259.1
GR130_05990		Streptomyces sp. GS7	QHC26716.1
GR130_28650		Streptomyces sp. GS7	QHC24752.1
KRR37_09715		Streptomyces sp. HNA39	UQA34003.1
LUV23_17310		Streptomyces sp. HNM0561	UHH23470.1
LUV23_04920		Streptomyces sp. HNM0561	UHH15754.1
MQE23_29165		Streptomyces sp. HP-A2021	UOB12875.1
M1P56_04370		Streptomyces sp. HU2014	UQI49206.1
N8I87_28230		Streptomyces sp. HUAS 15-9	UXY30055.1
QRN89_11960		Streptomyces sp. HUAS CB01	WJY50467.1
R2D22_24355		Streptomyces sp. HUAS YS2	WOX24340.1
R2D22_00655		Streptomyces sp. HUAS YS2	WOX19987.1
DRB96_14525		Streptomyces sp. ICC1	AWZ13327.1
DRB89_37545		Streptomyces sp. ICC4	AWZ10833.1
G7Z12_07325		Streptomyces sp. ID38640	QIK05874.1
G7Z12_24585		Streptomyces sp. ID38640	QIK08726.1
F1D59_23225		Streptomyces sp. INR7	QNE27306.1
RLT58_01640		Streptomyces sp. ITFR-16	WNI20696.1
RLT58_23955		Streptomyces sp. ITFR-16	WNI24756.1
RLT57_08240		Streptomyces sp. ITFR-21	WNI15515.1
RLT59_26285		Streptomyces sp. ITFR-6	WNI31902.1
G7Z13_12155		Streptomyces sp. JB150	QIJ62708.1
PPN52_12250		Streptomyces sp. JCM 35825	WCL85307.1
NOO62_14230		Streptomyces sp. Je 1-369	WAL95547.1
SLV14_005261		Streptomyces sp. Je 1-4	UYB42396.1
SLV14_001621		Streptomyces sp. Je 1-4	UYB39162.1
NEH83_11210		Streptomyces sp. JUS-F4	WKN14728.1
R9806_25295		Streptomyces sp. KN37	WPO73705.1
Lon26		Streptomyces sp. KUSC_F05	QUJ09173.1
DKB27_25115		Streptomyces sp. KY2	QNF57719.1
DKB27_22365		Streptomyces sp. KY2	QNF57272.1
STKY70_5268		Streptomyces sp. KY70	CAD5985499.1
STKY75_2335		Streptomyces sp. KY75	CAD5948891.1
RKE32_23655		Streptomyces sp. Li-HN-5-13	WNW40304.1
LRS74_22790		Streptomyces sp. LX-29	WFB11786.1
H3V39_10140		Streptomyces sp. M54	QSS94990.1
CFP59_05968 (Nagj_1)		Streptomyces sp. M56	AUA13798.1
CFP59_08289 (Nagj_2)		Streptomyces sp. M56	AUA16099.1
M444_12985		Streptomyces sp. Mg1	AKL66173.1
STRMOE7_14050		Streptomyces sp. MOE7	ARH95271.1
LUW75_16865		Streptomyces sp. MRC013	URM91366.1
KGS77_23655		Streptomyces sp. MST-110588	UNO44155.1
I3F59_008830		Streptomyces sp. MUM 178J	WRQ79458.1
P8A18_10290		Streptomyces sp. Mut1	WLQ33812.1
P8A18_32395		Streptomyces sp. Mut1	WLQ37856.1
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