Activities in Sub Family	Endo-β-1,4-glucanase (EC 3.2.1.4); Endo-β-1,6-glucanase (EC 3.2.1.75);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resources	CAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (1); Uniprot accession (1);

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
EML492_17285		Rhizobium rhizogenes A4	QUE79745.1			46
G6L54_015870		Rhizobium rhizogenes C16/80	WEO64532.1			46
G6M87_19690		Rhizobium rhizogenes CA75/95	QTG07798.1			46
Arad_4741		Rhizobium rhizogenes K84	ACM28380.1			46
F3X89_15940		Rhizobium rhizogenes LBA9402	QRM39954.1			46
CKA34_25570		Rhizobium sp. 11515TR	ASW09303.1			46
J5284_22315		Rhizobium sp. AB2/73	QYA15725.1			46
I8E17_24835		Rhizobium sp. AB2/73	UEQ83408.1			46
CCGE531_23885		Rhizobium sp. CCGE531	AYG69098.1			46
CCGE532_23390		Rhizobium sp. CCGE532	AYG75478.1			46
RTCIAT899_PC03740		Rhizobium tropici CIAT 899	AGB74548.1			46
DCC35_05320		Roseivirga pacifica 9dcg1	QCK14204.1			46
Sde_2993 (Gly5K)		Saccharophagus degradans 2-40	ABD82250.1			46
QFX18_05715		Saccharophagus degradans FZY0027	WGO99558.1			46
Sked_05710		Sanguibacter keddieii DSM 10542	ACZ20531.1			46
RJT10_13990		Segatella copri H-2379	WOF93553.1			46
RJT00_15085		Segatella copri H-2446	MDV3114661.1			46
RJT04_15190		Segatella copri H-2477	WOG31701.1			46
RJT05_14475		Segatella copri H-2489	WOF87325.1			46
RJT12_13670		Segatella copri H-2497	WOF96462.1			46
RJT09_07915		Segatella copri H-2632	MDV3106391.1			46
AW14_05765		Siansivirga zeaxanthinifaciens CC-SAMT-1	AJR03226.1			46
M5M_06645		Simiduia agarivorans SA1 = DSM 21679	AFU98524.1			46
Solca_1074		Solitalea canadensis DSM 3403	AFD06181.1			46
CA265_17250		Sphingobacteriaceae bacterium GW460-11-11-14-LB5	ARS41306.1			46
H8M03_11665		Sphingomonas sabuli sand1-3	QNM84110.1			46
O3305_13020		Sphingomonas sp. NIBR02145 NIBR 02145	WHU01132.1			46
SKP52_11255		Sphingopyxis fribergensis Kp5.2	AJA09151.1			46
KNJ79_08635		Sphingopyxis indica MC4	WOF44928.1			46
LH19_06705		Sphingopyxis macrogoltabida 203	ALJ12552.1			46
ATM17_13100		Sphingopyxis macrogoltabida 203N	AMU89974.1			46
AN936_06815		Sphingopyxis macrogoltabida EY-1	ALH80084.1			46
L7H23_04010		Sphingopyxis sp. BSN-002	UKK85287.1			46
EEB18_001105		Sphingopyxis sp. OPL5	QNO27624.1			46
E5675_09165		Sphingopyxis sp. PAMC25046	QCB54589.1			46
BWQ93_03660		Sphingopyxis sp. QXT-31	APZ97684.1			46
KEC45_11845		Sphingopyxis sp. USTB-05	USI75472.1			46
G3545_13020		Starkeya sp. ORNL1	QJP14480.1			46
BW730_17420		Tessaracoccus aquimaris NSG39	AQP49010.1			46
E2K93_08190		Thalassotalea sp. HSM 43	QBY04371.1			46
BgGlu1-1GH5		uncultured bacterium	AGN70391.1			46
ORF (fragment)		uncultured bacterium Ad_091_F22_contig1	AIF25943.1			46
ORF (fragment)		uncultured bacterium Ad_095_K16_contig2	AIF25967.1			46
ORF		uncultured bacterium contig00103(2014)	AIA99600.1			46
ORF		uncultured bacterium contig00110(2014)	AIA99611.1			46
glycoside hydrolase family 5 subfamily GH5_46 protein		uncultured Prevotella sp.	URH23947.1			46
SPPYR_1367		uncultured Sphingopyxis sp. isolate UC10	SBV32487.1			46
J4031_11030		Xylanibacter ruminicola KHP1	QVJ80218.1			46
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