Activities in Sub Family	Endo-β-1,4-glucanase (EC 3.2.1.4); Endo-β-1,6-glucanase (EC 3.2.1.75);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resources	CAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (1); Uniprot accession (1);

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
J2O02_01200		Elizabethkingia anophelis 277-17	UTG65199.1			46
GJV56_01200		Elizabethkingia anophelis 296-96	QGN21318.1			46
J2O09_01220		Elizabethkingia anophelis 313-22	UTG61614.1			46
BBD31_17685		Elizabethkingia anophelis 3375	AQW99617.1			46
J2N97_01205		Elizabethkingia anophelis 343-63	UTG57967.1			46
J2O05_01200		Elizabethkingia anophelis 344-1	UTG54212.1			46
J2O06_01205		Elizabethkingia anophelis 346-66	UTG50451.1			46
J2N98_01205		Elizabethkingia anophelis 346-72	UTG46710.1			46
J2N96_01205		Elizabethkingia anophelis 347-10	UTG42964.1			46
J2O07_01205		Elizabethkingia anophelis 347-50	UTG39041.1			46
J2N95_01205		Elizabethkingia anophelis 347-96	UTG34243.1			46
J2O10_01205		Elizabethkingia anophelis 348-50	UTG30502.1			46
J2O00_01205		Elizabethkingia anophelis 349-83	UTG26760.1			46
J2O11_01205		Elizabethkingia anophelis 351-72	UTG23016.1			46
J2O01_01205		Elizabethkingia anophelis 354-72	UTG19272.1			46
J2O12_01205		Elizabethkingia anophelis 354-87	UTG15542.1			46
J2N92_01205		Elizabethkingia anophelis 355-58	UTG11828.1			46
J2N99_01205		Elizabethkingia anophelis 356-17	UTG08086.1			46
J2O03_01205		Elizabethkingia anophelis 362-2	UTG04343.1			46
J2O04_01200		Elizabethkingia anophelis 367-19	UTG00593.1			46
EAAG1_003395		Elizabethkingia anophelis Ag1	ATC38950.1			46
CMV40_03395		Elizabethkingia anophelis AR4-6	ATC46307.1			46
CMV41_03395		Elizabethkingia anophelis AR6-8	ATC42631.1			46
EZBTHKR_0033		Elizabethkingia anophelis As1	KMU65265.1			46
QFB79_01235		Elizabethkingia anophelis AWYL_1	WGL69994.1			46
N7E57_01220		Elizabethkingia anophelis C08	UXM67863.1			46
A2T72_05995		Elizabethkingia anophelis CSID_3000521207	AMX51043.1			46
A2T74_05995		Elizabethkingia anophelis CSID_3015183678	AMR40947.1			46
A2T59_05995		Elizabethkingia anophelis CSID_3015183681	AMX54434.1			46
A4C56_05995		Elizabethkingia anophelis CSID_3015183684	AMX47582.1			46
AYC66_15190		Elizabethkingia anophelis E6809	AQX51947.1			46
EAVNNN508_00246		Elizabethkingia anophelis EAV_NNN508	CAI9677181.1			46
EAVNVB490_00247		Elizabethkingia anophelis EAV_NVB490	CAI9672888.1			46
EAVNVH72_00293		Elizabethkingia anophelis EAV_NVH72	CAI9677344.1			46
EAVVTKC53_00217		Elizabethkingia anophelis EAV_VTKC53	CAI9677121.1			46
BBD32_18635		Elizabethkingia anophelis F3201	AQX03335.1			46
AYC67_14480		Elizabethkingia anophelis F3543	AQX90158.1			46
AL491_12035		Elizabethkingia anophelis FDAARGOS_132	AVF48757.1			46
AL492_14445		Elizabethkingia anophelis FDAARGOS_134	AVF52752.1			46
A6J37_13020		Elizabethkingia anophelis FDAARGOS_198	ASV79474.1			46
M876_09195		Elizabethkingia anophelis FMS-007	AKH94743.1			46
BBD30_14625		Elizabethkingia anophelis JM-87	AQW95321.1			46
JUNP353_0224		Elizabethkingia anophelis JUNP 353	BBQ05653.1			46
KJX92_18540		Elizabethkingia anophelis MSU001	MCQ0432859.1			46
BD94_2438		Elizabethkingia anophelis NUHP1	AIL46213.1			46
glycosyl hydrolase family 5		Elizabethkingia anophelis OSUVM2	PKR36775.1			46
BAZ09_003395		Elizabethkingia anophelis R26	ATC35311.1			46
JQC76_01750		Elizabethkingia anophelis SEA01	QRI50250.1			46
EIY88_01195		Elizabethkingia anophelis SUE	QNV07981.1			46
QTN78_03400		Elizabethkingia anophelis Ytc	WJK00789.1			46
I6H88_16430		Elizabethkingia bruuniana FDAARGOS_1031	QQN58003.1			46
AYC65_05830		Elizabethkingia bruuniana G0146	AQX84552.1			46
U2S95_01200		Elizabethkingia miricola 2023CK-01286	WQM38884.1			46
VO54_00280		Elizabethkingia miricola BM10	AJW61769.1			46
CQS02_06605		Elizabethkingia miricola EM798-26	ATL43004.1			46
FE632_01255		Elizabethkingia miricola FL160902	QHQ85504.1			46
M9H57_01255		Elizabethkingia miricola HJS0526	WNG65409.1			46
QFB80_01255		Elizabethkingia miricola MEYL_1	WGL73681.1			46
LYZ41_01255		Elizabethkingia miricola Mir-N11	UIO96721.1			46
P0M31_01265		Elizabethkingia miricola NW-2-4	WER13508.1			46
FCS00_19005		Elizabethkingia sp. 2-6	QCO48349.1			46
JCR23_01235		Elizabethkingia sp. M8	QQM27132.1			46
BBD34_01270		Elizabethkingia ursingii G4123	AQX07360.1			46
KI430_00440		Epilithonimonas zeae ZM18	UQB68948.1			46
FAES_0276 (CelC)		Fibrella aestuarina BUZ 2	CCG98290.1			46
FAES_0277		Fibrella aestuarina BUZ 2	CCG98291.1			46
KM029_23325		Flammeovirga kamogawensis YS10	QWG09542.1			46
KM029_09835		Flammeovirga kamogawensis YS10	QWG05683.1			46
KM029_19170		Flammeovirga kamogawensis YS10	QWG09803.1			46
EI427_22605		Flammeovirga pectinis L12M1	AZQ65014.1			46
EI427_00815		Flammeovirga pectinis L12M1	AZQ60802.1			46
R9C00_17625		Flammeovirgaceae bacterium SG7u.111	WPO33524.1			46
SY85_09695		Flavisolibacter tropicus LCS9	ANE53403.1			46
GKR88_09000		Flavobacteriaceae bacterium isolate MH-Pat-all_autometa_1-8	QMU64410.1			46
SAMN03097699_2068		Flavobacteriaceae bacterium MAR_2010_188	SDB54986.1			46
HYN59_05905		Flavobacterium album HYN0059	AWH84681.1			46
HYN59_10320		Flavobacterium album HYN0059	AWH85488.1			46
FUA48_12530		Flavobacterium alkalisoli XS-5	QEE50374.1			46
LLY39_07380		Flavobacterium anhuiense T4	URM38359.1			46
M0M57_09550		Flavobacterium azooxidireducens IGB 4-14	UPQ77875.1			46
TRV642_1599		Flavobacterium collinsii TRV642	CAI2766547.1			46
J0383_08060		Flavobacterium endoglycinae BB8	QSW90754.1			46
M0M44_08065		Flavobacterium humidisoli MMS21-Er5	UPZ17295.1			46
BB050_01048		Flavobacterium johnsoniae GSE09	AOC94183.1			46
HYN48_06180		Flavobacterium magnum HYN0048	AWA29700.1			46
E1750_12245		Flavobacterium nackdongense GS13	QBN19535.1			46
HYN49_06485		Flavobacterium pallidum HYN0049	AWI25569.1			46
NLJ00_08260		Flavobacterium panici BSSL-CR3	UUF16101.1			46
Q1W71_20090		Flavobacterium pectinovorum ZE23VCel01	WKL47251.1			46
NLG42_07530		Flavobacterium plurextorum RSG-18	UUW10654.1			46
ALW18_03685		Flavobacterium psychrophilum Z1	AOE51692.1			46
AMR72_03685		Flavobacterium psychrophilum Z2	ALM48071.1			46
EAG11_20370		Flavobacterium sp. 140616W15	AYN06246.1			46
M4I44_07695		Flavobacterium sp. B183	URC14258.1			46
K5V07_07555		Flavobacterium sp. CHNK8	QZK90359.1			46
HAV12_021135		Flavobacterium sp. CLA17	QSB26835.1			46
LNP23_07695		Flavobacterium sp. F-323	UFH44095.1			46
LNP22_07635		Flavobacterium sp. F-70	UFH40138.1			46
MKO97_06595		Flavobacterium sp. HJ-32-4	UMY67041.1			46
QWY17_09775		Flavobacterium sp. JSWR-1	WLS81695.1			46
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