Glycoside Hydrolase Family 5 / Subf 46

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (175); Uniprot accession (12);
| 1 | 2 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 ACP_0988   Acidobacterium capsulatum ATCC 51196 ACO32108.1 C1F3J6   46
 ADH66_17150   Acutalibacter muris KB18 ASB42229.1     46
 Arad_4741   Agrobacterium radiobacter K84 ACM28380.1 B9JE34   46
 CDL62_05055   Alkalitalea saponilacus DSM 24412 ASB48549.1     46
 D6B99_03885 (fragment)   Arachidicoccus sp. KIS59-12 AYD49272.1     46
 BcellWH2_02558   Bacteroides cellulosilyticus WH2 ALJ59797.1     46
 Bache_0610   Bacteroides helcogenes P 36-108 ADV42635.1     46
 Bcav_4045   Beutenbergia cavernae DSM 12333 ACQ82286.1 C5C5E6   46
 CFK41_16325   Brachybacterium ginsengisoli DCY80 ATG56168.1     46
 JL11_05075   Brevundimonas sp. DS20 ALJ07781.1     46
 Cabys_2449   Caldithrix abyssi DSM 13497 LF13 APF19198.1     46
 CJA_2760 (Cel5G)   Cellvibrio japonicus Ueda107 ACE83242.1 B3PBJ3   46
 CBR65_11870   Cellvibrio sp. PSBB006 ARU28067.1     46
 COR50_17055   Chitinophaga caeni ATL48734.1     46
 Cpin_4149   Chitinophaga pinensis DSM 2588 ACU61608.1 C7PFA3   46
 Cpin_2580   Chitinophaga pinensis DSM 2588 ACU60063.1 C7PIX9   46
 CK934_22000   Chitinophaga sp. MD30 ASZ13439.1     46
 EGY05_12240   Chryseobacterium arthrosphaerae FDAARGOS_519 AYZ12643.1     46
 EG339_20490   Chryseobacterium bernardetii G0229 AZB26793.1     46
 EG351_06320   Chryseobacterium bernardetii H4638 AZB33268.1     46
 OK18_20175   Chryseobacterium gallinarum DSM 27622 AKK74617.1     46
 A0O34_17070   Chryseobacterium glaciei IHBB 10212 ANF52123.1     46
 NCTC11432_01654   Chryseobacterium gleum NCTC11432 VEE06458.1     46
 CEQ15_09855   Chryseobacterium indologenes FDAARGOS_337 ASE61769.1     46
 CRN76_10110   Chryseobacterium indologenes FDAARGOS_379 ATN05726.1     46
 EGY07_06710   Chryseobacterium indologenes FDAARGOS_510 AYZ35284.1     46
 EGX91_13630   Chryseobacterium indologenes FDAARGOS_537 AYY85516.1     46
 EG352_06150   Chryseobacterium indologenes H5559 AZB17376.1     46
 EG358_15405   Chryseobacterium indoltheticum ATCC 27950 AZA75067.1     46
 EG340_18585   Chryseobacterium indoltheticum G0211 AZA62902.1     46
 EG341_12090   Chryseobacterium lactis G0197 AZB04639.1     46
 EG342_21210   Chryseobacterium lactis KC_1864 AZA84251.1     46
 EG343_04620   Chryseobacterium nakagawai G0041 AZA89958.1     46
 NCTC13529_03476   Chryseobacterium nakagawai NCTC13529 VEH21378.1     46
 CJF12_01940   Chryseobacterium piperi ATCC BAA-1782 ASW73170.1     46
 EG349_00405   Chryseobacterium shandongense G0207 AZA85364.1     46
 EG350_08435   Chryseobacterium shandongense G0239 AZA57207.1     46
 EG353_18875   Chryseobacterium shandongense H5143 AZA97470.1     46
 EG344_19875   Chryseobacterium sp. G0162 AZB10931.1     46
 EG348_21040   Chryseobacterium sp. G0201 AZA55300.1     46
 glycoside hydrolase family 5 protein (Gh5)   Chryseobacterium sp. HT1 ANQ80467.1     46
 ATE47_09160   Chryseobacterium sp. IHB B 17019 ALR30684.1     46
 CHSO_3141 (Cel5G)   Chryseobacterium sp. StRB126 BAP32178.1     46
 CEY12_06845   Chryseobacterium sp. T16E-39 ASK29842.1     46
 D4L85_27735   Chryseolinea sp. KIS68-18 AYB34140.1     46
 EAV92_02530   Cohnella sp. 18JY8-7 AYQ71557.1     46
 EAV92_13780   Cohnella sp. 18JY8-7 AYQ73553.1     46
 FH5T_05835   Draconibacterium orientale FH5 AHW59284.1     46
 FH5T_15835   Draconibacterium orientale FH5 AHW60616.1     46
 FH5T_15850   Draconibacterium orientale FH5 AHW60619.1     46
 Echvi_1856   Echinicola vietnamensis DSM 17526 AGA78111.1     46
 BBD28_15770   Elizabethkingia anophelis 0422 AQW92006.1     46
 BBD31_17685   Elizabethkingia anophelis 3375 AQW99617.1     46
 EAAG1_003395   Elizabethkingia anophelis Ag1 ATC38950.1     46
 CMV40_03395   Elizabethkingia anophelis AR4-6 ATC46307.1     46
 CMV41_03395   Elizabethkingia anophelis AR6-8 ATC42631.1     46
 A2T72_05995   Elizabethkingia anophelis CSID_3000521207 AMX51043.1     46
 A2T74_05995   Elizabethkingia anophelis CSID_3015183678 AMR40947.1     46
 A2T59_05995   Elizabethkingia anophelis CSID_3015183681 AMX54434.1     46
 A4C56_05995   Elizabethkingia anophelis CSID_3015183684 AMX47582.1     46
 AYC66_15190   Elizabethkingia anophelis E6809 AQX51947.1     46
 AYC67_14480   Elizabethkingia anophelis F3543 AQX90158.1     46
 AL491_12035   Elizabethkingia anophelis FDAARGOS_132 AVF48757.1     46
 AL492_14445   Elizabethkingia anophelis FDAARGOS_134 AVF52752.1     46
 A6J37_13020   Elizabethkingia anophelis FDAARGOS_198 ASV79474.1     46
 M876_09195   Elizabethkingia anophelis FMS-007 AKH94743.1     46
 BD94_2438   Elizabethkingia anophelis NUHP1 AIL46213.1     46
 BAZ09_003395   Elizabethkingia anophelis R26 ATC35311.1     46
 AYC65_05830   Elizabethkingia bruuniana G0146 AQX84552.1     46
 BBD32_18635   Elizabethkingia endophytica F3201 AQX03335.1     46
 BBD30_14625   Elizabethkingia endophytica JM-87 AQW95321.1     46
 VO54_00280   Elizabethkingia miricola BM10 AJW61769.1     46
 CQS02_06605   Elizabethkingia miricola EM798-26 ATL43004.1     46
 BBD34_01270   Elizabethkingia ursingii G4123 AQX07360.1     46
 FAES_0276 (CelC)   Fibrella aestuarina BUZ 2 CCG98290.1     46
 FAES_0277   Fibrella aestuarina BUZ 2 CCG98291.1     46
 EI427_22605   Flammeovirga sp. L12M1 AZQ65014.1     46
 EI427_00815   Flammeovirga sp. L12M1 AZQ60802.1     46
 SY85_09695   Flavisolibacter tropicus LCS9 ANE53403.1     46
 SAMN03097699_2068   Flavobacteriaceae bacterium MAR_2010_188 SDB54986.1     46
 HYN59_05905   Flavobacterium album HYN0059 AWH84681.1     46
 HYN59_10320   Flavobacterium album HYN0059 AWH85488.1     46
 BB050_01048   Flavobacterium johnsoniae GSE09 AOC94183.1     46
 HYN48_06180   Flavobacterium magnum HYN0048 AWA29700.1     46
 HYN49_06485   Flavobacterium pallidum HYN0049 AWI25569.1     46
 ALW18_03685   Flavobacterium psychrophilum Z1 AOE51692.1     46
 AMR72_03685   Flavobacterium psychrophilum Z2 ALM48071.1     46
 EAG11_20370   Flavobacterium sp. 140616W15 AYN06246.1     46
 FORMA_08490   Formosa sp. Hel3_A1_48 AOR26020.1     46
 SAMN04488552_1342   Gramella sp. MAR_2010_102 SDR87160.1     46
 C7S20_04770   Gramella sp. SH35 AVR44631.1     46
 AciX8_0146   Granulicella mallensis MP5ACTX8 AEU34504.1     46
 AciX9_3975   Granulicella tundricola MP5ACTX9 ADW71249.1     46
 A4V00_11245   Hungateiclostridiaceae bacterium KB18 ANU54540.1     46
 N008_15060   Hymenobacter sp. APR13 AII53292.1     46
 Hsw_1830   Hymenobacter swuensis DY53 AHJ97425.1     46
 Hsw_1831   Hymenobacter swuensis DY53 AHJ97426.1     46
 Hsw_4192   Hymenobacter swuensis DY53 AHJ99787.1     46
 IALB_2593   Ignavibacterium album JCM 16511 AFH50296.1     46
 IALB_2578   Ignavibacterium album JCM 16511 AFH50281.1     46
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