Glycoside Hydrolase Family 5 / Subf 46

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (126); Uniprot accession (12);
| 1 | 2 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 ACP_0988   Acidobacterium capsulatum ATCC 51196 ACO32108.1 C1F3J6   46
 ADH66_17150   Acutalibacter muris KB18 ASB42229.1     46
 Arad_4741   Agrobacterium radiobacter K84 ACM28380.1 B9JE34   46
 CDL62_05055   Alkalitalea saponilacus DSM 24412 ASB48549.1     46
 BcellWH2_02558   Bacteroides cellulosilyticus WH2 ALJ59797.1     46
 Bache_0610   Bacteroides helcogenes P 36-108 ADV42635.1     46
 Bcav_4045   Beutenbergia cavernae DSM 12333 ACQ82286.1 C5C5E6   46
 JL11_05075   Brevundimonas sp. DS20 ALJ07781.1     46
 Cabys_2449   Caldithrix abyssi DSM 13497 LF13 APF19198.1     46
 CJA_2760 (Cel5G)   Cellvibrio japonicus Ueda107 ACE83242.1 B3PBJ3   46
 CBR65_11870   Cellvibrio sp. PSBB006 ARU28067.1     46
 Cpin_4149   Chitinophaga pinensis DSM 2588 ACU61608.1 C7PFA3   46
 Cpin_2580   Chitinophaga pinensis DSM 2588 ACU60063.1 C7PIX9   46
 CK934_22000   Chitinophaga sp. MD30 ASZ13439.1     46
 OK18_20175   Chryseobacterium gallinarum DSM 27622 AKK74617.1     46
 CEQ15_09855   Chryseobacterium indologenes FDAARGOS_337 ASE61769.1     46
 CJF12_01940   Chryseobacterium piperi ATCC BAA-1782 ASW73170.1     46
 glycoside hydrolase family 5 protein (Gh5)   Chryseobacterium sp. HT1 ANQ80467.1     46
 ATE47_09160   Chryseobacterium sp. IHB B 17019 ALR30684.1     46
 A0O34_17070   Chryseobacterium sp. IHBB 10212 ANF52123.1     46
 CHSO_3141 (Cel5G)   Chryseobacterium sp. StRB126 BAP32178.1     46
 CEY12_06845   Chryseobacterium sp. T16E-39 ASK29842.1     46
 FH5T_05835   Draconibacterium orientale FH5 AHW59284.1     46
 FH5T_15835   Draconibacterium orientale FH5 AHW60616.1     46
 FH5T_15850   Draconibacterium orientale FH5 AHW60619.1     46
 Echvi_1856   Echinicola vietnamensis DSM 17526 AGA78111.1     46
 BBD28_15770   Elizabethkingia anophelis 0422 AQW92006.1     46
 BBD31_17685   Elizabethkingia anophelis 3375 AQW99617.1     46
 EAAG1_003395   Elizabethkingia anophelis Ag1 ATC38950.1     46
 CMV40_03395   Elizabethkingia anophelis AR4-6 ATC46307.1     46
 CMV41_03395   Elizabethkingia anophelis AR6-8 ATC42631.1     46
 A2T72_05995   Elizabethkingia anophelis CSID_3000521207 AMX51043.1     46
 A2T74_05995   Elizabethkingia anophelis CSID_3015183678 AMR40947.1     46
 A2T59_05995   Elizabethkingia anophelis CSID_3015183681 AMX54434.1     46
 A4C56_05995   Elizabethkingia anophelis CSID_3015183684 AMX47582.1     46
 AYC66_15190   Elizabethkingia anophelis E6809 AQX51947.1     46
 AYC67_14480   Elizabethkingia anophelis F3543 AQX90158.1     46
 A6J37_13020   Elizabethkingia anophelis FDAARGOS_198 ASV79474.1     46
 M876_09195   Elizabethkingia anophelis FMS-007 AKH94743.1     46
 BD94_2438   Elizabethkingia anophelis NUHP1 AIL46213.1     46
 BAZ09_003395   Elizabethkingia anophelis R26 ATC35311.1     46
 BBD32_18635   Elizabethkingia endophytica F3201 AQX03335.1     46
 BBD30_14625   Elizabethkingia endophytica JM-87 AQW95321.1     46
 AYC65_05830   Elizabethkingia genomosp. 3 str. G0146 AQX84552.1     46
 BBD34_01270   Elizabethkingia genomosp. 4 str. G4123 AQX07360.1     46
 VO54_00280   Elizabethkingia miricola BM10 AJW61769.1     46
 FAES_0276 (CelC)   Fibrella aestuarina BUZ 2 CCG98290.1     46
 FAES_0277   Fibrella aestuarina BUZ 2 CCG98291.1     46
 SY85_09695   Flavisolibacter sp. LCS9 ANE53403.1     46
 SAMN03097699_2068   Flavobacteriaceae bacterium MAR_2010_188 SDB54986.1     46
 BB050_01048   Flavobacterium johnsoniae GSE09 AOC94183.1     46
 ALW18_03685   Flavobacterium psychrophilum Z1 AOE51692.1     46
 AMR72_03685   Flavobacterium psychrophilum Z2 ALM48071.1     46
 FORMA_08490   Formosa sp. Hel3_A1_48 AOR26020.1     46
 SAMN04488552_1342   Gramella sp. MAR_2010_102 SDR87160.1     46
 AciX8_0146   Granulicella mallensis MP5ACTX8 AEU34504.1     46
 AciX9_3975   Granulicella tundricola MP5ACTX9 ADW71249.1     46
 N008_15060   Hymenobacter sp. APR13 AII53292.1     46
 Hsw_1830   Hymenobacter swuensis DY53 AHJ97425.1     46
 Hsw_1831   Hymenobacter swuensis DY53 AHJ97426.1     46
 Hsw_4192   Hymenobacter swuensis DY53 AHJ99787.1     46
 IALB_2593   Ignavibacterium album JCM 16511 AFH50296.1     46
 IALB_2578   Ignavibacterium album JCM 16511 AFH50281.1     46
 SAMN04488563_5662   Jiangella alkaliphila DSM 45079 SDU77913.1     46
 SAMN04515683_3596   Leifsonia sp. 157MF SDK48195.1     46
 SAMN04515690_0614   Leifsonia sp. 197AMF SDH08119.1     46
 SAMN04515684_3169   Leifsonia sp. 466MF SDJ31820.1     46
 SAMN04515685_3578   Leifsonia sp. 467MF SEN57010.1     46
 SAMN04515686_1354   Leifsonia sp. 509MF SDN53108.1     46
 SAMN04515691_3403   Leifsonia sp. 98AMF SFM71868.1     46
 LC55x_4851   Lysobacter capsici 55 ALN88099.1     46
 CNO08_21910   Lysobacter capsici KNU-14 ATE74793.1     46
 GLE_3663   Lysobacter enzymogenes C3 ALN59007.1     46
 LEN_1451   Lysobacter enzymogenes M497-1 BAV96938.1     46
 LG3211_3660   Lysobacter gummosus 3.2.11 ALN92602.1     46
 MGMSR_3774   Magnetospirillum gryphiswaldense MSR-1 v2 CDL00989.1     46
 ALGA_0479   Marinifilaceae bacterium SPP2 BAX78872.1     46
 ALGA_4293   Marinifilaceae bacterium SPP2 BAX82583.1     46
 Mag101_05415   Microbulbifer agarilyticus GP101 AQQ67143.1     46
 MgSA37_00352   Mucilaginibacter gotjawali SA3-7 BAU52202.1     46
 SAMN05216490_1453   Mucilaginibacter mallensis MP1X4 SDS60303.1     46
 MuYL_0314   Mucilaginibacter sp. BJC16-A31 ASU32217.1     46
 A0256_04480   Mucilaginibacter sp. PAMC 26640 AMR34426.1     46
 Niako_6173   Niastella koreensis GR20-10 AEW02398.1     46
 Niako_6809   Niastella koreensis GR20-10 AEW03032.1     46
 SAMN05444173_0353   Opitutus sp. GAS368 SDR67812.1     46
 SAMN05444162_2941   Paenibacillaceae bacterium GAS479 SDT04871.1     46
 A3958_11995   Paenibacillus glucanolyticus 5162 ANA80645.1     46
 BBD41_11975   Paenibacillus ihbetae IHBB 9852 ANY73244.1     46
 R50912_23455   Paenibacillus sp. FSL R5-0912 AIQ42679.1     46
 R70723_16015   Paenibacillus sp. FSL R7-0273 AIQ47223.1     46
 R70331_15430   Paenibacillus sp. FSL R7-0331 AIQ52770.1     46
 Pjdr2_5185   Paenibacillus sp. JDR-2 ACT03796.1 C6D1U2   46
 CIC07_13665   Paenibacillus sp. RUD330 ASS67066.1     46
 GYMC10_0533   Paenibacillus sp. Y412MC10 ACX62836.1 D3EBM3   46
 Palpr_0244   Paludibacter propionicigenes WB4 ADQ78406.1 E4T125   46
 BFS30_02595   Pedobacter steynii DX4 AOM80596.1     46
 SAMN04487762_0491   Polaribacter sp. Hel1_33_78 SDT90904.1     46
 LPB03_04965 (fragment)   Polaribacter vadi LPB0003 AOW19003.1     46
 PKOR_00465 (fragment)   Pontibacter korlensis X14-1T AKD01895.1     46
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