Glycoside Hydrolase Family 5 / Subf 46

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (131); Uniprot accession (12);
| 1 | 2 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 CPT03_01320   Pedobacter ginsengisoli T01R-27 ATP55196.1     46
 BFS30_02595   Pedobacter steynii DX4 AOM80596.1     46
 SAMN04487762_0491   Polaribacter sp. Hel1_33_78 SDT90904.1     46
 LPB03_04965 (fragment)   Polaribacter vadi LPB0003 AOW19003.1     46
 PKOR_00465 (fragment)   Pontibacter korlensis X14-1T AKD01895.1     46
 Pedsa_2638   Pseudopedobacter saltans DSM 12145 ADY53180.1     46
 Pedsa_3079   Pseudopedobacter saltans DSM 12145 ADY53618.1     46
 WQ53_07680   Pseudoxanthomonas suwonensis J1 AKC86660.1     46
 CKA34_25570   Rhizobium sp. 10195 ASW09303.1     46
 RTCIAT899_PC03740   Rhizobium tropici CIAT 899 AGB74548.1     46
 A4V00_11245   Ruminiclostridium sp. KB18 ANU54540.1     46
 Sde_2993 (Gly5K)   Saccharophagus degradans 2-40 ABD82250.1 Q21GC9   46
 Sked_05710   Sanguibacter keddieii DSM 10542 ACZ20531.1 D1BAI0   46
 AW14_05765   Siansivirga zeaxanthinifaciens CC-SAMT-1 AJR03226.1     46
 M5M_06645   Simiduia agarivorans SA1 = DSM 21679 AFU98524.1     46
 Solca_1074   Solitalea canadensis DSM 3403 AFD06181.1     46
 CA265_17250   Sphingobacteriaceae bacterium GW460-11-11-14-LB5 ARS41306.1     46
 SKP52_11255   Sphingopyxis fribergensis Kp5.2 AJA09151.1     46
 LH19_06705   Sphingopyxis macrogoltabida 203 ALJ12552.1     46
 ATM17_13100   Sphingopyxis macrogoltabida 203N AMU89974.1     46
 AN936_06815   Sphingopyxis macrogoltabida EY-1 ALH80084.1     46
 BWQ93_03660   Sphingopyxis sp. QXT-31 APZ97684.1     46
 Snov_0472   Starkeya novella DSM 506 ADH87805.1 D7A387   46
 BW730_17420   Tessaracoccus sp. NSG39 AQP49010.1     46
 BgGlu1-1GH5   uncultured bacterium AGN70391.1     46
 ORF (fragment)   uncultured bacterium Ad_091_F22_contig1 AIF25943.1     46
 ORF (fragment)   uncultured bacterium Ad_095_K16_contig2 AIF25967.1     46
 ORF   uncultured bacterium contig00103(2014) AIA99600.1     46
 ORF   uncultured bacterium contig00110(2014) AIA99611.1     46
 SPPYR_1367   uncultured Sphingopyxis sp. SBV32487.1     46
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