Activities in Sub Family	Endo-β-1,4-glucanase (EC 3.2.1.4); Endo-β-1,6-glucanase (EC 3.2.1.75);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resources	CAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (1); Uniprot accession (1);

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
MUU74_11580		Chryseobacterium daecheongense F23	UOU97134.1			46
PFY10_05830		Chryseobacterium daecheongense PL22-22A	WBV57960.1			46
ODZ84_04605		Chryseobacterium sp. MMS21-Ot14	UZT98857.1			46
OK18_20175		Chryseobacterium gallinarum DSM 27622	AKK74617.1			46
FOB44_02445		Chryseobacterium gallinarum FDAARGOS_636	QIY89581.1			46
PE065_00565		Chryseobacterium gambrini DMF-6	WBX97759.1			46
CRDW_09430		Chryseobacterium gambrini DW100	BEV03569.1			46
PFY09_04630		Chryseobacterium gambrini PL22-1A	WBV53604.1			46
A0O34_17070		Chryseobacterium glaciei IHBB 10212	ANF52123.1			46
DDI74_06345		Chryseobacterium gleum 110146	QBJ85894.1			46
NCTC12078_01138		Chryseobacterium gleum 3012STDY6944375	VFB03149.1			46
I6I60_12245		Chryseobacterium gleum FDAARGOS_1103	QQY34488.1			46
NCTC11432_01654		Chryseobacterium gleum NCTC11432	VEE06458.1			46
NCTC11409_01205		Chryseobacterium indologenes 3012STDY6981895	VFA41206.1			46
JHW31_05905		Chryseobacterium indologenes 3125	QQQ72256.1			46
LJF28_11480		Chryseobacterium indologenes 742	UDQ52055.1			46
H3Z85_21690		Chryseobacterium indologenes DSM 16777	QPQ51787.1			46
PYS58_05820		Chryseobacterium indologenes Ery-6B	WET50647.1			46
CEQ15_09855		Chryseobacterium indologenes FDAARGOS_337	ASE61769.1			46
CRN76_10110		Chryseobacterium indologenes FDAARGOS_379	ATN05726.1			46
EGY07_06710		Chryseobacterium indologenes FDAARGOS_510	AYZ35284.1			46
EGX91_13630		Chryseobacterium indologenes FDAARGOS_537	AYY85516.1			46
FOB56_14700		Chryseobacterium indologenes FDAARGOS_648	QIX82414.1			46
EG352_06150		Chryseobacterium indologenes H5559	AZB17376.1			46
EU348_10310		Chryseobacterium indologenes StR 01	QBA21570.1			46
EG358_15405		Chryseobacterium indoltheticum ATCC 27950	AZA75067.1			46
EG340_18585		Chryseobacterium indoltheticum G0211	AZA62902.1			46
JJL46_19290		Chryseobacterium indoltheticum POL15	QQQ28187.1			46
EG341_12090		Chryseobacterium lactis G0197	AZB04639.1			46
EG342_21210		Chryseobacterium lactis KC_1864	AZA84251.1			46
EG343_04620		Chryseobacterium nakagawai G0041	AZA89958.1			46
NCTC13529_03476		Chryseobacterium nakagawai NCTC13529	VEH21378.1			46
M0D58_04825		Chryseobacterium nepalense AC3	UPQ76877.1			46
N0B40_03615		Chryseobacterium oranimense 33-M-3	UWX61370.1			46
CJF12_01940		Chryseobacterium piperi ATCC BAA-1782	ASW73170.1			46
KB553_06020		Chryseobacterium rhizoplanae XL97	UCA61085.1			46
EG349_00405		Chryseobacterium shandongense G0207	AZA85364.1			46
EG350_08435		Chryseobacterium shandongense G0239	AZA57207.1			46
EG353_18875		Chryseobacterium shandongense H5143	AZA97470.1			46
PGH12_05345		Chryseobacterium sp. CY350	WBZ96575.1			46
KYG33_06490		Chryseobacterium sp. D764	QXU50682.1			46
I6I61_04055		Chryseobacterium sp. FDAARGOS 1104	QQV03520.1			46
EG344_19875		Chryseobacterium sp. G0162	AZB10931.1			46
EG348_21040		Chryseobacterium sp. G0201	AZA55300.1			46
SFA27_08465		Chryseobacterium sp. HR92	WPO92719.1			46
glycoside hydrolase family 5 protein (Gh5)		Chryseobacterium sp. HT1	ANQ80467.1			46
ATE47_09160		Chryseobacterium sp. IHB B 17019	ALR30684.1			46
SD427_07765		Chryseobacterium sp. JJR-5R	WPO84219.1			46
CHRYMOREF3P_1051		Chryseobacterium sp. JV274 F3_Prior	CAD0219378.1			46
PQ459_08305		Chryseobacterium sp. KACC 21268	WDF48466.1			46
K0U91_12540		Chryseobacterium sp. LJ668	QYK15880.1			46
KIK00_06935		Chryseobacterium sp. MA9	UTX49983.1			46
LF887_14455		Chryseobacterium sp. MEBOG06	UKB82207.1			46
LF886_10455		Chryseobacterium sp. MEBOG07	UKB81386.1			46
KBP46_00440		Chryseobacterium sp. PCH239	QWT86389.1			46
RHP76_06185		Chryseobacterium sp. SG20098	WNI38065.1			46
CHSO_3141 (Cel5G)		Chryseobacterium sp. StRB126	BAP32178.1			46
CEY12_06845		Chryseobacterium sp. T16E-39	ASK29842.1			46
PZ898_06255		Chryseobacterium sp. WX	WFB69018.1			46
MKS83_04685		Chryseobacterium sp. Y16C	UMQ42988.1			46
KKI44_05290		Chryseobacterium sp. ZHDP1	QWA39625.1			46
LNP04_04475		Chryseobacterium turcicum C-17	UFH32981.1			46
D4L85_27735		Chryseolinea soli KIS68-18	AYB34140.1			46
N7277_01275		Cloacibacterium sp. TD35	WDT68263.1			46
KCTCHS21_48100		Cohnella abietis HS21	BBI35411.1			46
KCTCHS21_13840		Cohnella abietis HS21	BBI31985.1			46
FPL14_20780		Cohnella cholangitidis 1605-214	QMV43339.1			46
HH215_14470		Cohnella herbarum MFER-1	QJD88155.1			46
EAV92_02530		Cohnella sp. 18JY8-7	AYQ71557.1			46
EAV92_13780		Cohnella sp. 18JY8-7	AYQ73553.1			46
J4772_23425		Cohnella sp. LGH	QTH40524.1			46
COUCH_05755		Couchioplanes caeruleus TL65	UQU65820.1			46
KY500_04535		Cryobacterium sp. PAMC25264	QYF74469.1			46
Dfulv_13145		Dactylosporangium fulvum NRRL B-16292	UWP85117.1			46
FH5T_05835		Draconibacterium orientale FH5	AHW59284.1			46
FH5T_15835		Draconibacterium orientale FH5	AHW60616.1			46
FH5T_15850		Draconibacterium orientale FH5	AHW60619.1			46
DCPSUM001_29920		Dysgonomonas capnocytophagoides SMU001	BES62748.1			46
G7050_05325		Dysgonomonas sp. HDW5A	QIK59288.1			46
G7050_12915		Dysgonomonas sp. HDW5A	QIK60683.1			46
G7051_05585		Dysgonomonas sp. HDW5B	QIK53840.1			46
G7051_13280		Dysgonomonas sp. HDW5B	QIK55261.1			46
FKX85_09040		Echinicola soli LN3S3	QDH79168.1			46
Echvi_1856		Echinicola vietnamensis DSM 17526	AGA78111.1			46
GWR55_16085		Edaphobacter sp. 12200R-103	QHS53067.1			46
BBD28_15770		Elizabethkingia anophelis 0422	AQW92006.1			46
KUF65_01160		Elizabethkingia anophelis 090-MNO-R	UKZ00996.1			46
J2O08_01140		Elizabethkingia anophelis 2-14	UTF93340.1			46
J2N93_01200		Elizabethkingia anophelis 2-62	UTF89722.1			46
J2N94_01235		Elizabethkingia anophelis 2-8	UTF96936.1			46
KUF66_01220 (fragment)		Elizabethkingia anophelis 2002C02-176	UKY84843.1			46
KUF63_01160		Elizabethkingia anophelis 2002N07-090	UKY86886.1			46
KUF67_01220 (fragment)		Elizabethkingia anophelis 2008N07-201	UKY95471.1			46
KUF64_01245		Elizabethkingia anophelis 2008S01-229	UKY90372.1			46
PF435_01310		Elizabethkingia anophelis 2022CK-00262	WBS71503.1			46
Q8W09_01255		Elizabethkingia anophelis 2023CK-00282	WLJ07385.1			46
U2S78_01255		Elizabethkingia anophelis 2023CK-00934	WQI07864.1			46
KUF68_01245		Elizabethkingia anophelis 229-MNO-R	UKY97541.1			46
J2O02_01200		Elizabethkingia anophelis 277-17	UTG65199.1			46
GJV56_01200		Elizabethkingia anophelis 296-96	QGN21318.1			46
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