Glycoside Hydrolase Family 5 / Subf 25

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (135); Uniprot accession (23); PDB accession (16); 3D entries (3); cryst (0)
| 1 | 2 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 ORF (fragment)   uncultured bacterium ADV57620.1     25
 ORF (fragment)   uncultured bacterium ADV57621.1     25
 ORF (fragment)   uncultured bacterium ADV57622.1     25
 ORF (fragment)   uncultured bacterium ADV57625.1     25
 ORF (fragment)   uncultured bacterium ADV57626.1     25
 ORF (fragment)   uncultured bacterium ADV57628.1     25
 ORF (fragment)   uncultured bacterium ADV57629.1     25
 ORF (fragment)   uncultured bacterium ADV57631.1     25
 ORF (fragment)   uncultured bacterium ADV57633.1     25
 ORF   uncultured bacterium BAO65808.1     25
 endoglucanase (CellMM5.1;Cell5.1_3) 3.2.1.4 uncultured bacterium AID57617.1     25
 ORF   uncultured bacterium A2_10 AEW47942.1     25
 B1_GH5   uncultured bacterium B1_8 AEW47944.1     25
 B2_GH5   uncultured bacterium B2_18 AEW47949.1     25
 ORF   uncultured bacterium G2_7 AEW47966.1     25
 H2_GH5   uncultured bacterium H2_7 AEW47975.1     25
 endoglucanase   uncultured Dictyoglomus sp. ARO76321.1     25
 IMCC26134_05880   Verrucomicrobia bacterium IMCC26134 AKC82422.1     25
 SAMN05444156_2102   Verrucomicrobiaceae bacterium GAS474 SDU12473.1     25
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