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Glycoside Hydrolase Family 5 / Subf 25

Activities in Sub FamilyEndo-β-1,4-glucanase (EC 3.2.1.4);
Endo-β-1,4-mannanase (EC 3.2.1.78);
Endo-β-1,4-xylanase (EC 3.2.1.8);
Mechanism Retaining e
ClanGH-A
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (507); Uniprot accession (15); PDB accession (24); 3D entries (6); cryst (0)
Summary
Download GH5_25 (494) Taxonomic display Structure (6) Characterized (17)
| 1 | 2 | 3 | 4 | 5 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 AD2_02267   Acetivibrio thermocellus AD2 ALX09255.1     25
 bifunctional endo-β-1,4-glucanase / β-1,4-xylanase H (CelH;EgH;CtCelH;CtCel5E;Cthe_1472) (Lic26A;Cel5E) 3.2.1.4
3.2.1.8		 Acetivibrio thermocellus ATCC 27405 ABN52701.1
CCF82162.1		 H6SHY4
P16218		 4U3A[A,B]
4U5I[A,B]
4U5K[A,B]
5BYW[A,B,C,D,E] 		25
 Clo1313_2234   Acetivibrio thermocellus DSM 1313 ADU75267.1     25
 LQRI_2266   Acetivibrio thermocellus DSM 2360 LQRI ANV77007.1     25
 N1236_11705   Acetivibrio thermocellus M3 UWV46229.1     25
 endo-β-1,4-glucanase / β-1,3:1,4-glucanase H (CelH) (Lic26A;Cel5E) 3.2.1.4 Acetivibrio thermocellus NCIB 10682 AAA23225.1 H6SHY4
P16218		   25
 LQZ07_10230   Agarivorans sp. B2Z047 UQN44814.1     25
 OAG1_25940   Agarivorans sp. OAG1 BEU03794.1     25
 M0C34_12550   Agarivorans sp. TSD2052 UPW17078.1     25
 CA12_01410 (CelH)   Alienimonas californiensis CA12 QDT14073.1     25
 CDL62_01845   Alkalitalea saponilacus DSM 24412 ASB47982.1     25
 A4R43_02425   Amycolatopsis albispora WP1 AXB48222.1     25
 QRY02_10245   Amycolatopsis sp. DG1A-15b WIX90781.1     25
 ANT_18750   Anaerolinea thermophila UNI-1 BAJ63901.1     25
 ETAA8_27380 (CelH)   Anatilimnocola aggregata ETA_A8 QDU27649.1     25
 SAMN00777080_1515   Aquiflexum balticum DSM 16537 SMD42944.1     25
 G9X62_02975   Aquirufa lenticrescens 9H-EGSE UAJ13563.1     25
 FF099_13545   Aquisalinus flavus D11M-2 UNE48998.1     25
 OJF2_06410 (CelH)   Aquisphaera giovannonii OJF2 QEH32172.1     25
 DJ013_21585   Arcticibacterium luteifluviistationis SM1504 AWW00634.1     25
 Astex_2497   Asticcacaulis excentricus CB 48 ADU14148.1     25
 EM6_2485   Asticcacaulis excentricus M6 BBF81876.1     25
 LH365_15780   Asticcacaulis sp. AND118 UDF04861.1     25
 ATDW_24600   Asticcacaulis sp. DW145 BEV11964.1     25
 Q1W73_10525   Asticcacaulis sp. ZE23SCel15 WKL56134.1     25
 Cel5A   bacterium enrichment culture QCW05828.1     25
 NQ510_03685   Bacteroides uniformis ATCC 8492 UWO08064.1     25
 INE84_01438   Bacteroides uniformis CL06T06C18 QUT61766.1     25
 I6G58_01170   Bacteroides uniformis FDAARGOS_901 QQA30263.1     25
 QWU49_03685   Bacteroides uniformis JCM5828 WNG10214.1     25
 BaraCB756_17455   Bradyrhizobium arachidis CB756 UFW52675.1     25
 WN72_18180   Bradyrhizobium arachidis CCBAU 051107 QOZ68026.1     25
 QA635_11105   Bradyrhizobium australafricanum 5G1B WFU34904.1     25
 QA633_16465   Bradyrhizobium barranii CC1502 WFT98498.1     25
 J4G48_0018330   Bradyrhizobium barranii subsp. apii 38S5 UPT99869.1     25
 J4G43_019160   Bradyrhizobium barranii subsp. barranii 144S4 UEM16146.1     25
 QA636_10215   Bradyrhizobium brasilense CB627 WFU65857.1     25
 BcanWSM471_00740   Bradyrhizobium canariense WSM471 UFW41776.1     25
 BcanWU425_00535   Bradyrhizobium canariense WU425 UFW72290.1     25
 LPJ38_19365   Bradyrhizobium daqingense CCBAU 15774 UFS85856.1     25
 Bdiaspc4_17400   Bradyrhizobium diazoefficiens 110spc4 QBP22163.1     25
 HUW42_29450   Bradyrhizobium diazoefficiens 113-2 QLD44847.1     25
 HAU57_15490   Bradyrhizobium diazoefficiens 172S4 QIO92914.1     25
 JJB99_24990   Bradyrhizobium diazoefficiens 38_8 QQO12682.1     25
 BdzoCB1809_16880   Bradyrhizobium diazoefficiens CB1809 UFW61195.1     25
 RZR06_15925   Bradyrhizobium diazoefficiens CNPSo 10 WRJ01595.1     25
 T7685_15910   Bradyrhizobium diazoefficiens CNPSo 104 WRJ09842.1     25
 T8J92_15905   Bradyrhizobium diazoefficiens CNPSo 105 WRJ18112.1     25
 T7377_15920   Bradyrhizobium diazoefficiens CNPSo 106 WRJ26377.1     25
 T7326_15905   Bradyrhizobium diazoefficiens CNPSo 107 WRJ34627.1     25
 T7585_15910   Bradyrhizobium diazoefficiens CNPSo 108 WRJ42967.1     25
 T7939_15915   Bradyrhizobium diazoefficiens CNPSo 109 WRJ51240.1     25
 T8I15_15905   Bradyrhizobium diazoefficiens CNPSo 110 WRJ59579.1     25
 T7740_15905   Bradyrhizobium diazoefficiens CPAC 7 WRJ68083.1     25
 F07S3_38020   Bradyrhizobium diazoefficiens F07S3 BBZ93969.1     25
 H12S4_38730   Bradyrhizobium diazoefficiens H12S4 BCA02969.1     25
 BDHF08_35660   Bradyrhizobium diazoefficiens HF08 BCA11719.1     25
 BDHH15_35470   Bradyrhizobium diazoefficiens HH15 BCA20332.1     25
 QIH76_25130   Bradyrhizobium diazoefficiens K01E-Bd WLC13433.1     25
 QIH77_30395   Bradyrhizobium diazoefficiens K09F-Bd WLA71184.1     25
 QIH78_17925   Bradyrhizobium diazoefficiens N03B-Bd WLB41597.1     25
 NK6_7446   Bradyrhizobium diazoefficiens NK6 BAR60597.1     25
 QNN01_17345   Bradyrhizobium diazoefficiens S13E-Bd WLA69351.1     25
 QIH81_13320   Bradyrhizobium diazoefficiens S14C-Bd WLA59607.1     25
 AAV28_13865   Bradyrhizobium diazoefficiens USDA 110 AND88774.1     25
 blr3367   Bradyrhizobium diazoefficiens USDA 110 NP_770007.1
BAC48632.1		     25
 BD122_29925   Bradyrhizobium diazoefficiens USDA 122 APO54584.1     25
 JEY62_26750   Bradyrhizobium diazoefficiens USDA 122-Bd UQD87282.1     25
 XF1B_36230   Bradyrhizobium diazoefficiens XF1 BCE20942.1     25
 XF10B_35100 (fragment)   Bradyrhizobium diazoefficiens XF10 BCE90712.1     25
 XF11B_35430   Bradyrhizobium diazoefficiens XF11 BCE99522.1     25
 XF12B_35470   Bradyrhizobium diazoefficiens XF12 BCF08174.1     25
 XF13B_35230   Bradyrhizobium diazoefficiens XF13 BCF16832.1     25
 XF14B_36080   Bradyrhizobium diazoefficiens XF14 BCF25656.1     25
 XF15B_35610   Bradyrhizobium diazoefficiens XF15 BCF34490.1     25
 XF16B_34030   Bradyrhizobium diazoefficiens XF16 BCF42913.1     25
 XF17B_35380   Bradyrhizobium diazoefficiens XF17 BCF51900.1     25
 XF18B_35250   Bradyrhizobium diazoefficiens XF18 BCF60577.1     25
 XF19B_34080   Bradyrhizobium diazoefficiens XF19 BCF69055.1     25
 XF2B_35290   Bradyrhizobium diazoefficiens XF2 BCE29760.1     25
 XF3B_35340   Bradyrhizobium diazoefficiens XF3 BCE38503.1     25
 XF4B_35380   Bradyrhizobium diazoefficiens XF4 BCE47189.1     25
 XF5B_35680   Bradyrhizobium diazoefficiens XF5 BCE56056.1     25
 XF6B_35900   Bradyrhizobium diazoefficiens XF6 BCE64791.1     25
 DI395_18890   Bradyrhizobium diazoefficiens XF7 AWO90345.1     25
 DI395_18890   Bradyrhizobium diazoefficiens XF7 AWO90345.2     25
 XF8B_34810   Bradyrhizobium diazoefficiens XF8 BCE73370.1     25
 XF9B_35220   Bradyrhizobium diazoefficiens XF9 BCE82101.1     25
 QIH80_09990   Bradyrhizobium elkanii K02K-Be WLA50462.1     25
 QNJ80_08440   Bradyrhizobium elkanii K03D-Be WLB02001.1     25
 QIH83_34005   Bradyrhizobium elkanii K03I-Be WLB79304.1     25
 QNJ95_12430   Bradyrhizobium elkanii K07G-Be WLA42209.1     25
 QNJ96_33400   Bradyrhizobium elkanii S05J-Be WLA89895.1     25
 QNJ99_38860   Bradyrhizobium elkanii S15H-Be WLA81275.1     25
 QIH87_12550   Bradyrhizobium elkanii USDA 31-Be WLB11866.1     25
 BE61_31710   Bradyrhizobium elkanii USDA 61 BBB97737.1     25
 JEY66_11335   Bradyrhizobium elkanii USDA 76 UQD83338.1     25
 QIH86_36290   Bradyrhizobium elkanii USDA 94 WLC06389.1     25
 IC762_07520   Bradyrhizobium genosp. L BDV5419 QPF86139.1     25
 BjapCC829_14925   Bradyrhizobium japonicum CC829 UFW89738.1     25
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