Activities in Sub Family	Endo-β-1,4-glucanase (EC 3.2.1.4); Lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73); Exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resources	CAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (59); Uniprot accession (38); PDB accession (16); 3D entries (4); cryst (0)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
NUG21_18390		Xanthomonas sp. CFBP 8445	UYC11694.1			1
XSP_000637		Xanthomonas sp. CPBF 367	CAD1787546.1			1
XSP_000638		Xanthomonas sp. CPBF 426	CAD1787553.1			1
endo-β-1,4-glucanase	3.2.1.4	Xanthomonas sp. EC102	ACU30064.1	C7FFK1		1
HEP73_03831		Xanthomonas sp. GW	QNH22883.1			1
LMG31885_08220 (EngxcA)		Xanthomonas sp. LMG 31885	CAD7725239.1 CAD7725243.1			1
LMG31886_07280 (EngxcA)		Xanthomonas sp. LMG 31886 GBBC 2199	CAD7725061.1			1
LMG31887_07380 (EngxcA)		Xanthomonas sp. LMG 31887 GBBC 2202	CAD7720797.1			1
DGN21_03190		Xanthomonas sp. MLO165	QWM98446.1			1
HEP75_03753		Xanthomonas sp. SI	QNH14284.1			1
HEP74_03687		Xanthomonas sp. SS	QNH18515.1			1
IG630_03145		Xanthomonas sp. WG16 gxlp16	QOX03551.1			1
G4Q83_17390		Xanthomonas theicola CFBP 4691	QNH26160.1			1
LZE81_02060		Xanthomonas translucens B1FA	UII60829.1			1
LV507_02070		Xanthomonas translucens B8GF	UII64549.1			1
KCU57_17780		Xanthomonas translucens CFBP 8304	UKE50500.1			1
MO327_17680		Xanthomonas translucens CIX162	WLA11972.1			1
MO328_18015		Xanthomonas translucens CIX207	WLA08218.1			1
MO329_17785		Xanthomonas translucens CIX282	WLA04419.1			1
MO330_17965		Xanthomonas translucens CIX303	WLA00662.1			1
MO326_17355		Xanthomonas translucens CIX40	WLA15653.1			1
E4A48_14900		Xanthomonas translucens pv. cerealis 01	QDI05930.1			1
KHA79_17430		Xanthomonas translucens pv. cerealis CFBP 2541	UKE49100.1			1
KM563_17935		Xanthomonas translucens pv. graminis ART-Xtg2	WIH11931.1			1
KM433_01680		Xanthomonas translucens pv. graminis ART-Xtg29	WIH16265.1			1
KM579_20065		Xanthomonas translucens pv. graminis ART-Xtg9	WIH08601.1			1
KFS84_00615		Xanthomonas translucens pv. graminis LMG 726	UKE54534.1			1
KHF85_17810		Xanthomonas translucens pv. graminis NCPPB 3711	WIH07005.1			1
KFS86_02045		Xanthomonas translucens pv. hordei UPB458	UKE58564.1			1
KFS83_02045		Xanthomonas translucens pv. hordei UPB947	WIH01571.1			1
KM547_17385		Xanthomonas translucens pv. phlei LMG 730	UKE65415.1			1
K8O61_17300		Xanthomonas translucens pv. pistacia ICMP 16317	UKE69174.1			1
KM539_03035		Xanthomonas translucens pv. poae LMG 728	UKE63870.1			1
KAF26_17385		Xanthomonas translucens pv. secalis CFBP 2539	UKE43147.1			1
KBQ49_13435		Xanthomonas translucens pv. translucens CIX43	UNT98055.1			1
KBV71_15810		Xanthomonas translucens pv. translucens CIX95	UNU10664.1			1
RMA73_13825		Xanthomonas translucens pv. translucens CO236	WNJ25950.1			1
BN444_01265 (EngxcA)		Xanthomonas translucens pv. translucens DSM 18974	SCB06361.1			1
ISN30_04965		Xanthomonas translucens pv. translucens Km7	QSQ31203.1			1
ISN31_13945		Xanthomonas translucens pv. translucens Km8	QSQ32983.1			1
ISN32_16075		Xanthomonas translucens pv. translucens Km9	QSQ37301.1			1
ISN33_04455		Xanthomonas translucens pv. translucens XtKm33	QSQ42451.1			1
ISN34_04190		Xanthomonas translucens pv. translucens XtKm34	QSQ46098.1			1
WDV90_17670		Xanthomonas translucens pv. undulosa ARGTr 7-1	WXF83157.1			1
KCU58_17670		Xanthomonas translucens pv. undulosa CFBP 2055	UKE39438.1			1
RMA82_08680		Xanthomonas translucens pv. undulosa CO237	WNJ32418.1			1
F0H32_17990		Xanthomonas translucens pv. undulosa LW16	QEO28484.1			1
LTC53_17775		Xanthomonas translucens pv. undulosa MAI5034	UJB14769.1			1
F0H33_17780		Xanthomonas translucens pv. undulosa P3	QEN94972.1			1
ISN37_15800		Xanthomonas translucens pv. undulosa XtFa1	QSQ55858.1			1
ISN35_03365		Xanthomonas translucens pv. undulosa XtKm12	QSQ49701.1			1
ISN36_15430		Xanthomonas translucens pv. undulosa XtKm15	QSQ54667.1			1
ISN38_12325		Xanthomonas translucens pv. undulosa XtLr8	QSQ62078.1			1
FD63_17340		Xanthomonas translucens pv. undulosa Xtu 4699	AKK69117.1			1
MZO50_05560		Xanthomonas translucens pv. undulosa Xtu-UPB513	UPU49897.1			1
NX81_003230		Xanthomonas vasicola NCPPB 1060	AZR21532.1			1
NX08_003085		Xanthomonas vasicola NCPPB 902	AZR33624.1			1
NX80_018250		Xanthomonas vasicola pv. arecae NCPPB 2649	AZR28079.1			1
KWO_003210		Xanthomonas vasicola pv. musacearum NCPPB 4379	AZR29698.1			1
C7V42_03285		Xanthomonas vasicola pv. vasculorum SAM119	AVQ05795.1			1
CXP37_03290		Xanthomonas vasicola pv. vasculorum Xv1601	AZM69994.1			1
BJD12_15870		Xanthomonas vesicatoria ATCC 35937 LMG 911	APP76455.1			1
BI313_18810		Xanthomonas vesicatoria LM159	APO96357.1			1
XFC3_10855		Xylella fastidiosa 3124	ALQ97780.1			1
endoglucanase (XF0818)	3.2.1.4	Xylella fastidiosa 9a5c	AAF83628.1 NP_298108.1	Q9PF60		1
F7G16_10590		Xylella fastidiosa ATCC 35879	QIS26545.1			1
RO838_10460		Xylella fastidiosa CFBP8478	WNY21156.1			1
RO839_10440		Xylella fastidiosa CO33	WNY18868.1			1
XFFB_11575		Xylella fastidiosa Fb7	ALR09719.1			1
XFHB_11215		Xylella fastidiosa Hib4	ALR07320.1			1
PT012_10020		Xylella fastidiosa ICMP 8740	WDF06772.1			1
OY18_11145		Xylella fastidiosa J1a12	ALR02657.1			1
XfasM23_1953		Xylella fastidiosa M23	ACB93352.1			1
P303_00585		Xylella fastidiosa MUL0034	AIC13500.1			1
XFPR_10465		Xylella fastidiosa Pr8x	ALR04981.1			1
BCV75_09730		Xylella fastidiosa Salento-1	AVI21393.1			1
BC375_09795		Xylella fastidiosa Salento-2	AVI23428.1			1
FG899_10410		Xylella fastidiosa subsp. fastidiosa Bakersfield-1	QID15759.1			1
IUD21_09935		Xylella fastidiosa subsp. fastidiosa Bakersfield-11	QPC08418.1			1
IUD22_09830		Xylella fastidiosa subsp. fastidiosa Bakersfield-13	QPC06257.1			1
IUD25_09830		Xylella fastidiosa subsp. fastidiosa Bakersfield-14	QPC04110.1			1
IUD20_09955		Xylella fastidiosa subsp. fastidiosa Bakersfield-8	QPC10602.1			1
OK117_10775		Xylella fastidiosa subsp. fastidiosa CFBP8073	WCF28096.1			1
XFLM_03715		Xylella fastidiosa subsp. fastidiosa GB514	ADN62717.1			1
XFGV230_09640		Xylella fastidiosa subsp. fastidiosa GV230	QNH30391.1			1
D1605_009910		Xylella fastidiosa subsp. fastidiosa IVIA5235	QMT64655.1			1
LZ758_10690		Xylella fastidiosa subsp. morus Riv11	UIT43207.1			1
IUD23_06255		Xylella fastidiosa subsp. morus Riv16	UIN26940.1			1
LZ757_10665		Xylella fastidiosa subsp. morus Riv19	UIT36474.1			1
LZ755_10695		Xylella fastidiosa subsp. morus Riv25	UIT38764.1			1
KBP49_09430		Xylella fastidiosa subsp. multiplex AlmaEM3	QTX27749.1			1
KBP48_09855		Xylella fastidiosa subsp. multiplex BB08-1	QTX29751.1			1
LOK86_06880		Xylella fastidiosa subsp. multiplex CFBP8432	WDN61542.1			1
HKJ31_10060		Xylella fastidiosa subsp. multiplex Fillmore	QJP49065.1			1
DVT08_010200		Xylella fastidiosa subsp. multiplex IVIA5901	QMT66830.1			1
HKJ32_10940		Xylella fastidiosa subsp. multiplex LM10	QJP56840.1			1
LZ754_10375		Xylella fastidiosa subsp. multiplex Oak 35874	UIT47548.1			1
HKJ33_10670		Xylella fastidiosa subsp. multiplex RH1	QJP51265.1			1
IUD19_09545		Xylella fastidiosa subsp. multiplex Riv5	QPC02011.1			1
O4444_09865		Xylella fastidiosa subsp. pauca ALM4	WGZ31787.1			1
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