| Activities in Family | β-glucosidase (EC 3.2.1.21); xylan 1,4-β-xylosidase (EC 3.2.1.37); β-glucosylceramidase (EC 3.2.1.45); β-N-acetylhexosaminidase (EC 3.2.1.52); α-L-arabinofuranosidase (EC 3.2.1.55); glucan 1,4-β-glucosidase (EC 3.2.1.74); isoprimeverose-producing oligoxyloglucan hydrolase (EC 3.2.1.120); coniferin β-glucosidase (EC 3.2.1.126); exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-); β-1,2-glucosidase (EC 3.2.1.-); β-1,3-glucosidase (EC 3.2.1.-); xyloglucan-specific exo-β-1,4-glucanase / exo-xyloglucanase (EC 3.2.1.155); stevioside-β-1,2-glucosidase (EC 3.2.1.-); lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73); protodioscin 26-O-β-D-glucosidase (EC 3.2.1.186); β-glucuronidase (EC 3.2.1.31); avenacinase (EC 3.2.1.-); tomatinase β-1,2-glucosidase (EC 3.2.1.-) |
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| Mechanism | Retaining |
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| 3D Structure Status | ( β / α ) 8 barrel |
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| Catalytic Nucleophile/Base | Asp (experimental); |
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| Catalytic Proton Donor | Glu for hydrolases (experimental); histidine for phosphorylases (experimental) |
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| Note | A recent paper by Macdonald et al. (PMID=25533455) has shown that some enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases. |
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| External resources | CAZypedia; HOMSTRAD; PRINTS; PROSITE; |
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| Commercial Enzyme Provider(s) | MEGAZYME; PROZOMIX ; |
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| Statistics | GenBank accession (48397); Uniprot accession (325); PDB accession (181); 3D entries (54); cryst (4) |
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