Glycoside Hydrolase Family 3

Activities in Familyβ-glucosidase (EC 3.2.1.21); xylan 1,4-β-xylosidase (EC 3.2.1.37); β-glucosylceramidase (EC 3.2.1.45); β-N-acetylhexosaminidase (EC 3.2.1.52); α-L-arabinofuranosidase (EC 3.2.1.55); glucan 1,4-β-glucosidase (EC 3.2.1.74); isoprimeverose-producing oligoxyloglucan hydrolase (EC 3.2.1.120); coniferin β-glucosidase (EC 3.2.1.126); exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-); β-1,2-glucosidase (EC 3.2.1.-); β-1,3-glucosidase (EC 3.2.1.-); xyloglucan-specific exo-β-1,4-glucanase / exo-xyloglucanase (EC 3.2.1.155); stevioside-β-1,2-glucosidase (EC 3.2.1.-); lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73); protodioscin 26-O-β-D-glucosidase (EC 3.2.1.186); β-glucuronidase (EC 3.2.1.31); avenacinase (EC 3.2.1.-); tomatinase β-1,2-glucosidase (EC 3.2.1.-)
Mechanism Retaining
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that some enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (48397); Uniprot accession (325); PDB accession (181); 3D entries (54); cryst (4)
| 1 | 2 | 3 | 4 |
Eukaryota
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 β-glucosidase 2 (Bgl; BGL-2; BGL2) (fragment) 3.2.1.21 pubmed
Talaromyces amestolkiae CIB AKK32386.1    
 β-glucosidase 3 (BGL-3; BGL3; Bgl) (fragment) 3.2.1.21 pubmed
Talaromyces amestolkiae CIB AKK32385.1    
 β-glucosidase 3A (TCE0_039f12945) (Bgl3A) 3.2.1.21 pubmed
Talaromyces cellulolyticus Y-94 GAM40530.1 A0A6N4SLD2  
 β-glucosidase (Bgl3) (Bgl3A) 3.2.1.21 pubmed
Talaromyces funiculosus NCL1 AFU91382.1 K4KB38  
 β-xylosidase (Bxy3A) 3.2.1.37 pubmed
Talaromyces pinophilus CF-2612 / FERM BP-5826 BAK96214.1 G3XFU3  
 β-xylosidase (Xyl2;XYL2) 3.2.1.37 pubmed
Talaromyces purpureogenus ATCC MYA-38 AKH40279.1 A0A0F7KMN1  
 β-glucosidase (Bgl3;Bgl) 3.2.1.21 pubmed
Talaromyces purpureogenus KJS506 (KACC 93053P) ACV87737.1 C9E9M9  
 β-glucosidase (Bgl2;BGLII;Bg2;BGII) 3.2.1.21 pubmed
Thermoascus aurantiacus IFO 9748 AAY33982.1
AAY33983.1
Q4U4W7  
 β-glucosidase (Bgl1;Bg1;TaBgl1) 3.2.1.21 pubmed
Thermoascus aurantiacus IFO 9748 AAZ95587.1
AAZ95588.1
Q0ZUL0  
 β-glucosidase (Bgl) 3.2.1.21 pubmed
Thermochaetoides thermophila CT2 ABR57325.2
ABI63598.1
ABR57325.1
A6YRT4
Q09IZ3
6SZ6[A]
 β-glucosidase (MYCTH_80304) 3.2.1.21 pubmed
Thermothelomyces thermophilus ATCC 42464 AEO58175.1 G2QCQ3  
 β-glucosidase (MtBgl3a;MYCTH_66804) (Bgl3A) 3.2.1.21 pubmed
Thermothelomyces thermophilus ATCC 42464 AEO58343.1 G2QDN2  
 β-glucosidase (TkBgl3A) (Bgl3A) 3.2.1.21 doi
Trichoderma koningiopsis FCD3-1 AIB10099.1 A0A060DHV5  
 β-xylosidase (Bxl1; TrXyl3A) (Xyl3A) 3.2.1.37 pubmed
Trichoderma reesei CAA93248.1
CAW52645.1
CBC23920.1
Q92458 5A7M[A,B]
5AE6[A,B]
 β-glucosidase (HjCel3B) (Cel3B) 3.2.1.21 pubmed
Trichoderma reesei QM6A AAP57755.1
ABE16061.1
Q7Z9M5  
 β-glucosidase 1 (Bgl1;Bgl-1;TrBGL1;HjCel3A) (Cel3A) 3.2.1.21 pubmed
Trichoderma reesei QM9414 AAA18473.1 Q12715 3ZYZ[A]
3ZZ1[A]
4I8D[A,B]
 β-glucosidase I (Bgl1;BGL1;VbglI) 3.2.1.21 pubmed
Trichoderma viride AS 3.3711 ACS93768.1 C6GGC9  
 β-glucosidase 3.2.1.21 pubmed
Tropaeolum majus CAA07070.1 O82074  
 β-glucosidase (Bgl1) 3.2.1.21 pubmed
Uromyces viciae-fabae CAE01320.1 Q70KQ7  
 β-glucosidase (UeBgl3A) (Bgl3A) 3.2.1.21 pubmed
Ustilago esculenta NBRC 9887 BAK61808.1 F8WRJ0  
 UM04032.1 (Umay-Bgl101) 3.2.1.21 pubmed
Ustilago maydis 521 EAK85129.1    
 β-glucosidase (Bgl;BGL-II) 3.2.1.21 pubmed
Volvariella volvacea V14 AAG59831.1 Q9C3Z9  
 β-glucosidase 3.2.1.21 pubmed
Wickerhamomyces anomalus VAR. ACETAETHERIUS CAA26662.1 P06835  
 β-glucosidase (Exg1) 3.2.1.21 pubmed
Zea mays AAF79936.1
CAC21961.1
Q9LLB8  
 β-xylosidase 3.2.1.37 doi
Zea mays BZ3 CAW52613.1
ACL54109.1
CAW96523.1
CAW96686.1
CAX01900.1
CAX07254.1
CBC23853.1
CBD30890.1
B8A1R0  
unclassified
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 β-glucosidase (JMB19063) 3.2.1.21 pubmed
compost metagenome     3U48[B]
3U4A[A,B]
3U48[A]
 broad-specificity β-glucosidase/β-xylosidase (GlyA1) (partial) 3.2.1.21
3.2.1.37
pubmed
pubmed
metagenome     5K6M[A]
5K6N[A]
5K6O[A]
5K6L[A]
 β-glucosidase (Unglu135B12;TY-135-138) 3.2.1.21 pubmed
uncultured microorganism AFX98011.1 K7YKQ9  
 β-glucosidase (UmCel3G) 3.2.1.21 pubmed
uncultured microorganism ABU68675.1 A7Y421  
 β-xylosidase (G06-24) 3.2.1.37 pubmed
uncultured organism ACY24766.1 D8VMY1  
 β-glucanase 3.2.1.- pubmed
uncultured organism ADD62001.1 D9ZF97  
 SARM_0077 / 0_03232 / TW-71 (fragment; probable frameshift) 3.2.1.73 pubmed
uncultured organism ADX05759.1 E9NSR4  
 CelEx-SF301 3.2.1.21 doi
uncultured organism AGK74984.1 N0CJ17  
 c53_8 3.2.1.37 pubmed
uncultured organism AGU11176.1 T1W912  
 β-glucosidase (c84_2) 3.2.1.21
3.2.1.37
pubmed
pubmed
uncultured organism AGU12029.1 T1WBZ1  
 β-xylosidase / xylanase E2 3.2.1.37 pubmed
unidentified AEF56854.1    
 β-glucosidase A3 3.2.1.21 pubmed
unidentified AEF56853.1    
 β-glucosidase (UmCelC7;Cb1) 3.2.1.21 pubmed
unidentified microorganism ABX76049.1 A9UGW5  
 β-glucosidase (UmCelS19;Sb1) 3.2.1.21 pubmed
unidentified microorganism ABX76051.1 A9UID4  
Top


Last update: 2022-07-07 © Copyright 1998-2022
AFMB - CNRS - Université d'Aix-Marseille