Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (5159); Uniprot accession (686); PDB accession (146); 3D entries (19); cryst (0)
All (4922) Archaea (1) Bacteria (4488) Eukaryota (393) Viruses (34) unclassified (6) Structure (19) Characterized (96)
| 1 | ... | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | ... | 46 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CNX73_03735   Helicobacter pylori AVH12002.1    
 hp2017_0567   Helicobacter pylori 2017 ADZ49660.1    
 hp2018_0569   Helicobacter pylori 2018 ADZ51263.1    
 lipid A Kdo hydrolase (KdhA;HP0580;HP_0580) 3.2.1.- Helicobacter pylori 26695 AAD07646.1
NP_207375.1
   
 C694_02990   Helicobacter pylori 26695 AFV41799.1    
 SE87_03000   Helicobacter pylori 26695-1 AJF08862.1    
 SE88_03000   Helicobacter pylori 26695-1MET AJF10403.1    
 C2840_03015   Helicobacter pylori 26695-dR AUV77764.1    
 C2843_03010   Helicobacter pylori 26695-dRdM1dM2 AUV76274.1    
 C2842_03015   Helicobacter pylori 26695-dRdM2 AUV79273.1    
 OA23_03865   Helicobacter pylori 29CaP ALM79357.1    
 HMPREF4655_21021   Helicobacter pylori 35A ADU41116.1 D6UJN0  
 BXP18_03735   Helicobacter pylori 7.13_1 AVG85439.1    
 BXP19_03730   Helicobacter pylori 7.13_2 AVG84000.1    
 BXP20_03765   Helicobacter pylori 7.13_3 AVG82582.1    
 BXP08_03740   Helicobacter pylori 7.13_D1a AVH00239.1    
 BXP09_03725   Helicobacter pylori 7.13_D1b AVH01687.1    
 BXP10_03730   Helicobacter pylori 7.13_D1c AVH03145.1    
 BXP11_03735   Helicobacter pylori 7.13_D2a AVH04591.1    
 BXP13_03740   Helicobacter pylori 7.13_D2b AVH06072.1    
 BXP14_03740   Helicobacter pylori 7.13_D2c AVH07555.1    
 BXP15_03735   Helicobacter pylori 7.13_D3a AVH09036.1    
 BXP16_03735   Helicobacter pylori 7.13_D3b AVH10519.1    
 BXP21_03740   Helicobacter pylori 7.13_R1a AVG86924.1    
 BXP22_03735   Helicobacter pylori 7.13_R1b AVG88407.1    
 BXP23_03735   Helicobacter pylori 7.13_R1c AVG89891.1    
 BXP02_03740   Helicobacter pylori 7.13_R2a AVG91374.1    
 BXP03_03735   Helicobacter pylori 7.13_R2b AVG92857.1    
 BXP04_03730   Helicobacter pylori 7.13_R2c AVG94345.1    
 BXP05_03735   Helicobacter pylori 7.13_R3a AVG95825.1    
 BXP06_03740   Helicobacter pylori 7.13_R3b AVG97312.1    
 BXP07_03735   Helicobacter pylori 7.13_R3c AVG98797.1    
 APV63_03795   Helicobacter pylori 7C ALM80811.1    
 HMPREF0462_0836   Helicobacter pylori 83 AEE70441.1    
 hp908_0587   Helicobacter pylori 908 ADN79715.1 E1S885  
 HPAKL117_02740   Helicobacter pylori Aklavik117 AFX90961.1    
 HPAKL86_01960   Helicobacter pylori Aklavik86 AFX89409.1    
 HPATCC43504_00776   Helicobacter pylori ATCC 43504 BBI22711.1    
 AA973_03695   Helicobacter pylori ausabrJ05 ANH46952.1    
 BXP01_03735   Helicobacter pylori B128_1 AVG73637.1    
 BXP12_03725   Helicobacter pylori B128_2 AVG79687.1    
 BXP17_03730   Helicobacter pylori B128_3 AVG81157.1    
 HPB8_776   Helicobacter pylori B8 CBI66333.1 D7FDR2  
 U063_0885   Helicobacter pylori BM012A AHA88231.1    
 EG66_04700   Helicobacter pylori BM012B AHZ28421.1    
 U064_0889   Helicobacter pylori BM012S AHA89804.1    
 AA976_03095 (fragment)   Helicobacter pylori CC33C ANH45375.1    
 C2841_03005   Helicobacter pylori dRdM1 AUV74778.1    
 C2844_03010   Helicobacter pylori dRdM2addM2 AUZ23793.1    
 EE66_03520   Helicobacter pylori DU15 ANH44778.1    
 HPELS_03670   Helicobacter pylori ELS37 AFF20280.1    
 HPF13_0814   Helicobacter pylori F13 BAW36479.1    
 HPF16_0779   Helicobacter pylori F16 BAJ55376.1    
 neuraminidase   Helicobacter pylori F17 BAW37675.1    
 neuraminidase   Helicobacter pylori F18 BAW39310.1    
 HPF20_0472   Helicobacter pylori F20 BAW42278.1    
 HPF209_0787   Helicobacter pylori F209 BAW41071.1    
 HPF21_0681   Helicobacter pylori F21 BAW47082.1    
 HPF210_0828   Helicobacter pylori F210 BAW44147.1    
 HPF211_0796   Helicobacter pylori F211 BAW45679.1    
 HPF23_0470   Helicobacter pylori F23 BAW48401.1    
 HPF24_0792   Helicobacter pylori F24 BAW50232.1    
 HPF28_0583   Helicobacter pylori F28 BAW51533.1    
 HPF30_0747   Helicobacter pylori F30 BAJ56844.1    
 HPF32_0555   Helicobacter pylori F32 BAJ58137.1    
 neuraminidase   Helicobacter pylori F38 BAW53325.1    
 neuraminidase   Helicobacter pylori F51 BAW54597.1    
 HPF55_0591   Helicobacter pylori F55 BAW56180.1    
 HPF57_0605   Helicobacter pylori F57 BAJ59679.1    
 neuraminidase   Helicobacter pylori F63 BAW57973.1    
 HPF67_0813   Helicobacter pylori F67 BAW59541.1    
 neuraminidase   Helicobacter pylori F70 BAW61065.1    
 HPF72_0588   Helicobacter pylori F72 BAW62437.1    
 HPF75_0803   Helicobacter pylori F75 BAW64215.1    
 HPF78_0824   Helicobacter pylori F78 BAW65830.1    
 HPF90_0586   Helicobacter pylori F90 BAW67199.1    
 HPF94_0673   Helicobacter pylori F94 BAW68832.1    
 CEP77_08210   Helicobacter pylori FDAARGOS_298 AVV97570.1    
 CEP79_06305   Helicobacter pylori FDAARGOS_300 AVL49141.1    
 CGC32_03455   Helicobacter pylori G272 ASM63712.1    
 HPGAM_02985 (fragment)   Helicobacter pylori Gambia94/24 ADU81437.1    
 DZC36_03460   Helicobacter pylori GD63 AYJ08411.1    
 CYK58_03425   Helicobacter pylori H-137 AZP94634.1    
 OI67_02945   Helicobacter pylori Hp238 AJD65570.1    
 D8X56_03065   Helicobacter pylori HP42K AZL52125.1    
 C1I82_02895   Helicobacter pylori Hp_TH2099 AYQ44996.1    
 HPB14_03790   Helicobacter pylori HUP-B14 AFI07457.1    
 HPIN_03975 (fragment)   Helicobacter pylori India7 ADU80023.1    
 EG65_04135   Helicobacter pylori J166 AHZ25469.1    
 YH61_02150   Helicobacter pylori J99 AKE81484.1    
 AA977_02635   Helicobacter pylori K26A1 ANH48116.1    
 AA971_03670   Helicobacter pylori L7 ANH42562.1    
 HPLT_02885 (fragment)   Helicobacter pylori Lithuania75 ADU83003.1    
 neuraminidase   Helicobacter pylori MKF10 BAW70499.1    
 neuraminidase   Helicobacter pylori MKF3 BAW71840.1    
 neuraminidase   Helicobacter pylori MKF8 BAW73578.1    
 HPMKM1_0586   Helicobacter pylori MKM1 BAW74903.1    
 HPMKM5_0804   Helicobacter pylori MKM5 BAW76640.1    
 HPMKM6_0579   Helicobacter pylori MKM6 BAW77961.1    
 NCTC11637_00801 (fragment)   Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 SQJ04891.1    
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