Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (6599); Uniprot accession (681); PDB accession (152); 3D entries (21); cryst (0)
All (6360) Archaea (1) Bacteria (5882) Eukaryota (433) Viruses (38) unclassified (6) Structure (21) Characterized (97)
| 1 | ... | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | ... | 60 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 Dd586_3498   Dickeya zeae Ech586 ACZ78328.1 D2BWH5  
 Dd586_4080   Dickeya zeae Ech586 ACZ78906.1 D2BZN4  
 C1O30_17610   Dickeya zeae MS2 AUQ26749.1    
 C1O30_20680   Dickeya zeae MS2 AUQ27312.1    
 FNV33_08675   Dolosigranulum pigrum 83VPs-KB5 QDO92420.1    
 FNV33_08675   Dolosigranulum pigrum 83VPs-KB5 QDO92420.1    
 FNV33_02275   Dolosigranulum pigrum 83VPs-KB5 QDO90937.1    
 B5772_08380   Dolosigranulum pigrum KPL1914 QJS96926.1    
 B5772_02165   Dolosigranulum pigrum KPL1914 QJS95822.1    
 B8A41_03985   Dolosigranulum pigrum KPL1934_CDC4709-98 QJS97803.1    
 B8A41_08245   Dolosigranulum pigrum KPL1934_CDC4709-98 QJS98584.1    
 FH5T_01145   Draconibacterium orientale FH5 AHW58654.1    
 FH5T_13900   Draconibacterium orientale FH5 AHW60355.1    
 HH213_26560   Duganella sp. AF9R3 QJD93332.1    
 FDZ78_06670 (fragment)   Duncaniella sp. B8 QCP72278.1    
 E7745_02940 (fragment)   Duncaniella sp. C9 QCD38586.1    
 Dfer_2148   Dyadobacter fermentans DSM 18053 ACT93371.1 C6VYL6  
 Dfer_2863   Dyadobacter fermentans DSM 18053 ACT94078.1 C6W4H7  
 Dfer_3020   Dyadobacter fermentans DSM 18053 ACT94235.1 C6W5L7  
 G7050_15395   Dysgonomonas sp. HDW5A QIK61146.1    
 G7050_15120   Dysgonomonas sp. HDW5A QIK61096.1    
 G7051_15890   Dysgonomonas sp. HDW5B QIK55749.1    
 FKX85_16345   Echinicola sp. LN3S3 QDH80524.1    
 FKX85_07945   Echinicola sp. LN3S3 QDH78971.1    
 FKX85_02160   Echinicola sp. LN3S3 QDH81455.1    
 DN752_14255   Echinicola strongylocentroti MEBiC08714 AWW31195.1    
 DN752_04810   Echinicola strongylocentroti MEBiC08714 AWW29506.1    
 neuraminidase   Echinicola vietnamensis DSM 17526 AGA76790.1    
 Echvi_1665   Echinicola vietnamensis DSM 17526 AGA77930.1    
 Echvi_4341   Echinicola vietnamensis DSM 17526 AGA80527.1    
 GWR55_01240   Edaphobacter sp. 12200R-103 QHS50523.1    
 GWR55_08550   Edaphobacter sp. 12200R-103 QHS51785.1    
 GWR55_18095   Edaphobacter sp. 12200R-103 QHS53406.1    
 ETEE_3198 (fragment)   Edwardsiella anguillarum ET080813 AIJ09625.1    
 A9798_10455   Edwardsiella hoshinae ATCC 35051 AOV98594.1    
 ETAC_05915   Edwardsiella piscicida C07-087 AGH73308.1    
 GT752_16980   Edwardsiella piscicida CK41 QHR96911.1    
 BXA22_01835   Edwardsiella piscicida ETW41 ARD17174.1    
 EVK84_01165   Edwardsiella piscicida MS-18-199 QBB14338.1    
 A9797_06095   Edwardsiella piscicida S11-285 AOP42629.1    
 sialidase NanA   Edwardsiella tarda E01-21 BAV69399.1    
 NanA sialidase   Edwardsiella tarda E22 BAX03532.1    
 NanA sialidase   Edwardsiella tarda E381 BAV59436.1    
 ETAE_1245   Edwardsiella tarda EIB202 ACY84088.1 D0ZFQ6  
 ORF   Edwardsiella tarda ET-1 BAU80413.1    
 ETAF_1161   Edwardsiella tarda FL6-60 ADM41276.1 E0T4S6  
 sialidase (NanA)   Edwardsiella tarda FPC 498 BAP91033.1    
 NanA sialidase   Edwardsiella tarda NUF806 BAV59437.1    
 NanA sialidase   Edwardsiella tarda SU138 BAX36558.1    
 NanA sialidase   Edwardsiella tarda SU226 BAX03533.1    
 sialidase (NanA) 3.2.1.18 Edwardsiella tarda TX01 AFP73415.1    
 EVD20_04340   Elizabethkingia bruuniana ATCC 33958 QDZ62216.1    
 BBD33_05820   Elizabethkingia meningoseptica G4076 AQX04795.1    
 BBD35_07650   Elizabethkingia meningoseptica G4120 AQX12256.1    
 B5G46_05815   Elizabethkingia meningoseptica KC1913 AQX46837.1    
 EVD19_14095   Elizabethkingia meningoseptica KC1913 QDZ61267.1    
 NCTC10016_01251 (Neda_2)   Elizabethkingia meningoseptica NCTC10016 SQG06338.1    
 FE632_03085   Elizabethkingia miricola FL160902 QHQ85835.1    
 FGE20_10510   Elizabethkingia sp. JS20170427COW QCX54140.1    
 Emtol_2335   Emticicia oligotrophica DSM 17448 AFK03472.1    
 neuraminidase   Emticicia oligotrophica DSM 17448 AFK05157.1    
 neuraminidase   Emticicia oligotrophica DSM 17448 AFK05192.1    
 EZMO1_1737 (fragment)   Endozoicomonas montiporae CL-33 AMO55886.1    
 EZMO1_1736 (fragment)   Endozoicomonas montiporae CL-33 AMO55885.1    
 FA04_32600   Ensifer adhaerens Casida A ANK77378.1    
 DQW09_34285   Ensifer adhaerens Corn53 QHG74793.1    
 OV14_b0333   Ensifer adhaerens OV14 AHK46900.1    
 SJ05684_c15290   Ensifer sojae CCBAU 05684 ASY62971.1    
 AB190_04710   Enterobacter asburiae CAV1043 AKK99904.1
AZL61628.1
   
 A0R60_0918   Enterobacter asburiae ENIPBJ-CG1 AMX05225.1    
 Entas_2142   Enterobacter asburiae LF7a AEN64876.1    
 FY206_12365   Enterobacter chengduensis WCHECl-C4 = WCHECh050004 QEL36164.1    
 GJ694_12010   Enterobacter cloacae CBG15936 QGN42878.1    
 E7739_15145   Enterobacter cloacae Effluent_2 QCC97247.1    
 E7735_15450   Enterobacter cloacae Effluent_3 QCC92246.1    
 E7729_09470   Enterobacter cloacae Effluent_4 QCD10819.1    
 EC036_21440   Enterobacter cloacae GGT036 AIV29791.1    
 BFJ73_10280   Enterobacter cloacae isolate SBP-8 AOE95581.1    
 BJM06_02266   Enterobacter cloacae M12X01451 ASQ18057.1    
 FGL54_02045   Enterobacter cloacae NH77 QCZ37336.1    
 B2J95_12170   Enterobacter cloacae Res2010EC27 AVL18757.1    
 ECL_02001   Enterobacter cloacae subsp. cloacae ATCC 13047 ADF61553.1 D5C8V6  
 A3UG_11160   Enterobacter cloacae subsp. dissolvens SDM AFM59966.1    
 GBN88_15985   Enterobacter roggenkampii WCHER090065 QFQ84211.1    
 FR762_00460   Enterobacter sp. E76 QFH68329.1    
 FR762_18730   Enterobacter sp. E76 QFH71628.1    
 AKI40_3003   Enterobacter sp. FY-07 AMO49388.1    
 CRX67_10380   Enterobacteriaceae bacterium A-F18 QIH63490.1    
 C2U51_16240   Enterobacteriaceae bacterium ENNIH1 AUV02432.1    
 C2U51_09030   Enterobacteriaceae bacterium ENNIH1 AUV01143.1    
 C2U52_22480   Enterobacteriaceae bacterium ENNIH2 AUV08826.1    
 C2U55_19795   Enterobacteriaceae bacterium ENNIH3 AUU91156.1    
 neuraminidase   Enterobacteriaceae bacterium strain FGI 57 AGB78182.1    
 FOC47_10705   Enterocloster clostridioformis FDAARGOS_739 QIX90982.1    
 EH197_06870   Enterococcus avium 352 QCQ11920.1    
 AUF16_05065   Enterococcus avium FDAARGOS_184 AYQ24055.1    
 GFU50_17885   Enterococcus casseliflavus EC291 QGN31358.1    
 NCTC12421_02418 (NanB)   Enterococcus cecorum NCTC12421 SQE57351.1    
 neuraminidase   Enterococcus durans BDGP3 ASV96651.1    
 FS851_11315   Enterococcus durans VREdu QED60981.1    
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