Activities in Family	Laccase / p-diphenol:oxygen oxidoreductase / ferroxidase (EC 1.10.3.2); ; ferroxidase (EC 1.10.3.-); Laccase-like multicopper oxidase (EC 1.10.3.-)
Note	The characterized AA1 enzymes are multicopper oxidases that use diphenols and related substances as donors with oxygen as the acceptor. The AA1 family is currently divided into 3 subfamilies including laccases, ferroxidases and laccase-like multicopper oxidases.
Statistics	GenBank accession (6141); Uniprot accession (79); PDB accession (89); 3D entries (25); cryst (0)

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Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
HYE68_001730		Fusarium pseudograminearum Class2-1C	QPC70978.1
HYE68_003075		Fusarium pseudograminearum Class2-1C	QPC72323.1			3
HYE68_003512		Fusarium pseudograminearum Class2-1C	QPC72760.1			3
laccase		Fusarium solani MAS2	AGT80114.1			3
laccase		Fusarium solani MAS2	AHD26939.1			3
laccase 4 (Lcc4)		Fusarium solani X701	AHZ65139.1			3
laccase 3 (Lcc3)		Fusarium solani X701	AHZ65140.1			2
laccase 2 (Lcc2)		Fusarium solani X701	AHZ65141.1			3
laccase 1 (Lcc1)		Fusarium solani X701	AHZ65142.1			2
LCI18_013550		Fusarium solani-melongenae CRI 24-3	UPL02616.1			3
LCI18_012397		Fusarium solani-melongenae CRI 24-3	UPL01463.1			3
LCI18_014111		Fusarium solani-melongenae CRI 24-3	UPL03177.1
LCI18_013308		Fusarium solani-melongenae CRI 24-3	UPL02374.1
LCI18_010976		Fusarium solani-melongenae CRI 24-3	UPL00042.1
LCI18_012717		Fusarium solani-melongenae CRI 24-3	UPL01783.1			2
LCI18_002608		Fusarium solani-melongenae CRI 24-3	UPK91673.1
LCI18_010772		Fusarium solani-melongenae CRI 24-3	UPK99837.1
LCI18_006678		Fusarium solani-melongenae CRI 24-3	UPK95743.1			3
LCI18_000498		Fusarium solani-melongenae CRI 24-3	UPK89563.1			3
LCI18_006435		Fusarium solani-melongenae CRI 24-3	UPK95500.1			3
LCI18_011392		Fusarium solani-melongenae CRI 24-3	UPL00458.1
LCI18_000194		Fusarium solani-melongenae CRI 24-3	UPK89259.1			2
LCI18_013647 (fragment)		Fusarium solani-melongenae CRI 24-3	UPL02713.1			2
LCI18_008411		Fusarium solani-melongenae CRI 24-3	UPK97476.1			3
FVRRES_00253		Fusarium venenatum A3/5	CEI63741.1			3
FVRRES_06499		Fusarium venenatum A3/5	CEI62063.1
FVRRES_03852 (fragment)		Fusarium venenatum A3/5	CEI67340.1
FVRRES_02721		Fusarium venenatum A3/5	CEI66209.1
FVRRES_13565		Fusarium venenatum A3/5	CEI41409.1			3
FVRRES_13070		Fusarium venenatum A3/5	CEI40379.1			3
FVRRES_02719		Fusarium venenatum A3/5	CEI66207.1
FVRRES_04202		Fusarium venenatum A3/5	CEI67690.1			3
FVRRES_12638		Fusarium venenatum A3/5	CEI39947.1
FVRRES_09128		Fusarium venenatum A3/5	CEI69051.1			2
FVRRES_10878		Fusarium venenatum A3/5	CEI70801.1			3
FVRRES_02528		Fusarium venenatum A3/5	CEI66016.1			2
FVRRES_06498		Fusarium venenatum A3/5	CEI62062.1
Probable 3-oxoacyl- (Q8y0j2) (fragment)		Ganoderma boninense	VWO97713.1
AA_TRNA_LIGASE_II domain-containing protein (I1s216) (fragment)		Ganoderma boninense	VWO98855.1
Probable 3-oxoacyl- (Q8y0j2) (fragment)		Ganoderma boninense	VWP00117.1			1
Protein kinase domain-containing protein, partial (I1rtc2) (fragment)		Ganoderma boninense	VWP01816.1			1
Probable 3-oxoacyl- (Q8y0j2) (fragment)		Ganoderma boninense	VWO97716.1
Chitinase, partial (O59928) (fragment)		Ganoderma boninense	VWP00472.1			2
Tetraspanin (Q8j0e2)		Ganoderma boninense	VWO98767.1			1
Uncharacterized protein (Q1ha66) (fragment)		Ganoderma boninense	VWO98460.1			1
Uncharacterized protein (I1rp25)		Ganoderma boninense	VWP02110.1			1
Response regulatory domain-containing protein, partial (G4n7y2)		Ganoderma boninense	VWP01815.1			1
Laccase (Putative laccase) (J7mf98) (fragment)		Ganoderma boninense	VWO94029.1
Multicopper oxidase (E3q7g1) (fragment)		Ganoderma boninense	VWO94449.1			1
Laccase-2 (EC (Benzenediol:oxygen oxidoreductase 2) (Diphenol oxidase 2) (Urishiol oxidase 2) (Q96wm9) (fragment)		Ganoderma boninense	VWO94451.1			1
Multicopper oxidase (E3q7g1)		Ganoderma boninense	VWO94184.1			1
Calcium dependent mitochondrial carrier protein (G4nci6)		Ganoderma boninense	VWO94552.1			1
Multicopper oxidase, partial (E3q7g1) (fragment)		Ganoderma boninense	VWO97008.1
Laccase-2 (EC (Benzenediol:oxygen oxidoreductase 2) (Diphenol oxidase 2) (Urishiol oxidase 2), partial (Q96wm9) (fragment)		Ganoderma boninense	VWO96453.1			1
Laccase-2 (EC (Benzenediol:oxygen oxidoreductase 2) (Diphenol oxidase 2) (Urishiol oxidase 2) (Q96wm9) (fragment)		Ganoderma boninense	VWO96452.1			1
laccase GbLac_U90667		Ganoderma boninense	QOW95915.1			1
laccase GbLac_U30636		Ganoderma boninense	QOW95913.1			1
laccase GbLac_U36023		Ganoderma boninense	QOW95914.1			1
laccase (Lac1)		Ganoderma fornicatum 0814	ABK59827.1			1
laccase (Lac1)		Ganoderma fornicatum 0814	ABK59826.1			1
laccase		Ganoderma lucidum	AAR82930.1 AAR82934.1			1
Lac2 (fragment)		Ganoderma lucidum	CAD12768.1			1
laccase (GlLac1)	1.10.3.2	Ganoderma lucidum 7071-9	AAG17009.2 ACN38062.1	Q9HG17		1
laccase (Lcc1;Glac15)	1.10.3.2	Ganoderma lucidum CGMCC5.0026	AHA83584.1	V9PQZ7		1
laccase, partial (Lcc5)		Ganoderma lucidum CGMCC5.0026	AHA83588.1			1
laccase, partial (Lcc15)		Ganoderma lucidum CGMCC5.0026	AHA83598.1			2
laccase, partial (Lcc3)		Ganoderma lucidum CGMCC5.0026	AHA83586.1			1
laccase, partial (Lcc10)		Ganoderma lucidum CGMCC5.0026	AHA83593.1			1
laccase, partial (Lcc2)		Ganoderma lucidum CGMCC5.0026	AHA83585.1			1
laccase, partial (Lcc4)		Ganoderma lucidum CGMCC5.0026	AHA83587.1			1
laccase, partial (Lcc11)		Ganoderma lucidum CGMCC5.0026	AHA83594.1			1
laccase, partial (Lcc6) (fragment)		Ganoderma lucidum CGMCC5.0026	AHA83589.1			1
laccase, partial (Lcc7) (fragment)		Ganoderma lucidum CGMCC5.0026	AHA83590.1			1
laccase, partial (Lcc8) (fragment)		Ganoderma lucidum CGMCC5.0026	AHA83591.1			1
laccase, partial (Lcc9)		Ganoderma lucidum CGMCC5.0026	AHA83592.1			1
laccase, partial (Lcc12) (fragment)		Ganoderma lucidum CGMCC5.0026	AHA83595.1			1
laccase, partial (Lcc13) (fragment)		Ganoderma lucidum CGMCC5.0026	AHA83596.1			1
laccase, partial (Lcc14)		Ganoderma lucidum CGMCC5.0026	AHA83597.1
laccase		Ganoderma lucidum RCK2011	AFY52524.1			1
laccase (Lac4)		Ganoderma lucidum RZ	ABK59823.1			1
laccase (Lac4)		Ganoderma lucidum RZ	ABK59822.1			1
Lac3 (fragment)		Ganoderma lucidum RZ	ABK59821.1			1
Lac1 (fragment)		Ganoderma lucidum RZ	ABK59818.1			1
Lac2 (fragment)		Ganoderma lucidum RZ	ABK59820.1			1
laccase	1.10.3.2	Ganoderma lucidum TR6	ACR24357.1	C5HL41		1
laccase (fragment)		Ganoderma sp. BAFC2488	AAR04343.1			1
laccase 2 (fragment)		Ganoderma sp. BS-1	AAR04342.1			1
laccase 1 (fragment)		Ganoderma sp. BS-1	AAR04341.1			1
laccase		Ganoderma sp. En3	ADK55594.1			1
laccase (fragment)		Ganoderma sp. kk-02 KK-2003	CAE52290.2			1
laccase enzyme, partial (fragment)		Ganoderma sp. UH-A	SJL35391.1 SJL35392.1 SJL35393.1
laccase enzyme, partial (fragment)		Ganoderma sp. UH-B	SJL35394.1 SJL35395.1 SJL35396.1 SJL35397.1
laccase enzyme, partial (fragment)		Ganoderma sp. UH-C	SJL35398.1 SJL35399.1 SJL35400.1
laccase enzyme, partial (fragment)		Ganoderma sp. UH-D	SJL35401.1
laccase enzyme, partial (fragment)		Ganoderma sp. UH-F	SJL35403.1 SJL35404.1
laccase enzyme, partial (fragment)		Ganoderma sp. UH-G	SJL35405.1 SJL35406.1
laccase enzyme, partial (fragment)		Ganoderma sp. UH-H	SJL35407.1 SJL35408.1
laccase enzyme, partial (fragment)		Ganoderma sp. UH-I	SJL35409.1
laccase enzyme, partial (fragment)		Ganoderma sp. UH-J	SJX72066.1			1
laccase enzyme, partial (fragment)		Ganoderma sp. UH-J	SJX72065.1			1
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