Activities in Family	Laccase / p-diphenol:oxygen oxidoreductase / ferroxidase (EC 1.10.3.2); ; ferroxidase (EC 1.10.3.-); Laccase-like multicopper oxidase (EC 1.10.3.-)
Note	The characterized AA1 enzymes are multicopper oxidases that use diphenols and related substances as donors with oxygen as the acceptor. The AA1 family is currently divided into 3 subfamilies including laccases, ferroxidases and laccase-like multicopper oxidases.
Statistics	GenBank accession (6872); Uniprot accession (79); PDB accession (89); 3D entries (25); cryst (0)

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Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
laccase 4 allele B (Lcc4B)		Lentinula edodes L54-A	AGO04560.1			1
laccase 5 (Lcc5)	1.10.3.2	Lentinula edodes L54-A	AGO04561.1	R9WU11		1
laccase 7 (Lcc7)	1.10.3.2	Lentinula edodes L54-A	AGO04562.1	R9WS76		1
laccase 8 (Lcc8)		Lentinula edodes L54-A	AGO04563.1			1
laccase 10 (Lcc10)		Lentinula edodes L54-A	AGO04565.1			2
laccase 11 (Lcc11)		Lentinula edodes L54-A	AGO04566.1
laccase 3 (Lcc3)		Lentinula edodes L54-A	AGO04558.1			1
laccase lcc6 (Lcc6)		Lentinula edodes SR-1	BAJ12090.1			1
laccase lcc5 (Lcc5)		Lentinula edodes SR-1	BAJ12091.1			1
laccase 1 (Lac1)		Lentinus sajor-caju	CAD45377.1			1
laccase 4 (Lac4)		Lentinus sajor-caju	CAD45380.1			1
laccase 2 (Lac2)		Lentinus sajor-caju	CAD45378.1			1
laccase 5 (Lac5)		Lentinus sajor-caju	CAD45381.1			1
laccase 3 (Lac3)		Lentinus sajor-caju	CAD45379.1			1
laccase 4 (Lac4)		Lentinus sajor-caju P32-1	AAG27436.1			1
Lac1 (fragment)		Lentinus sajor-caju P32-1	AAG27433.1
Lac2 (fragment)		Lentinus sajor-caju P32-1	AAG27434.1
laccase (Lcc3;Lcc-3)	1.10.3.2	Lentinus sp. WR2	ACZ82339.1	I3NL60		1
laccase (Lcc4)	1.10.3.2	Lentinus sp. WR2	AIT51846.1	A0A0F6NTZ1	3X1B[A,B]	1
laccase (Lcc1) (fragment)		Lentinus tigrinus	AAX07469.1		2QT6[A,B]	1
laccase (Lac2) (fragment)		Lentinus tigrinus CBS 577.79	CAL91950.1			1
Lac2 (fragment)		Lentinus tigrinus CBS 577.79	CAL91948.1			1
Lac1 (fragment)		Lentinus tigrinus CBS 577.79	CAL91947.1			1
laccase H		Lenzites betulinus	AYR00606.1			1
laccase F		Lenzites betulinus	AYR00604.1			1
laccase G		Lenzites betulinus	AYR00605.1			1
laccase D		Lenzites betulinus	AYR00603.1			1
laccase B		Lenzites betulinus	AYR00602.1			1
laccase A		Lenzites betulinus	AYR00601.1			1
laccase (fragment)		Lenzites betulinus	AFQ90522.1			1
LSINAPIS_LOCUS15327 (fragment)		Leptidea sinapis	VUZ05915.1
LSINAPIS_LOCUS14348 (fragment)		Leptidea sinapis	VUZ04686.1
laccase 2		Leptinotarsa decemlineata	WCN84858.1
Lac1, partial (fragment)		Leptosphaerulina sp. LVN6	AID53021.1			3
Lac2, partial (fragment)		Leptosphaerulina sp. LVN6	AID53022.1
Lac4, partial (fragment)		Leptosphaerulina sp. LVN6	AID53024.1			3
Lac3, partial (fragment)		Leptosphaerulina sp. LVN6	AID53023.1			3
laccase (Lcc5)		Leucoagaricus gongylophorus Ae322	AFV15789.1			1
laccase (Lcc1)		Leucoagaricus gongylophorus Ae322	AFV15785.1			1
laccase (Lcc2)		Leucoagaricus gongylophorus Ae322	AFV15786.1			1
laccase (Lcc3)		Leucoagaricus gongylophorus Ae322	AFV15787.1			1
laccase (Lcc6)		Leucoagaricus gongylophorus Ae322	AFV15790.1			1
laccase (Lcc7)		Leucoagaricus gongylophorus Ae322	AFV15791.1			1
laccase (Lcc8)		Leucoagaricus gongylophorus Ae322	AFV15792.1			1
laccase (Lcc9)		Leucoagaricus gongylophorus Ae322	AFV15793.1			2
laccase (Lcc4) (fragment)		Leucoagaricus gongylophorus Ae322	AFV15788.1			1
laccase, partial (Lcc1) (fragment)		Leucocoprinus sp. Cyp.lon.C#012_180507	AFV15795.1			1
laccase (Lcc1)		Leucocoprinus sp. Tra.sp1.C#004_270408	AFV15794.1			1
ls5930a1_00020		Leucosporidium scottii	CRX78957.1			2
LRAMOSA05050		Lichtheimia ramosa	CDS12866.1			2
LRAMOSA04726		Lichtheimia ramosa	CDS12532.1
LRAMOSA06733		Lichtheimia ramosa	CDS03778.1			2
LRAMOSA08713		Lichtheimia ramosa	CDS06185.1
LRAMOSA02612		Lichtheimia ramosa	CDS09935.1			2
LRAMOSA09079		Lichtheimia ramosa	CDS06551.1
LRAMOSA01210		Lichtheimia ramosa	CDS07261.1
laccase (Lac1)		Lignosus rhinocerotis	AXY79772.1			1
laccase (Lac4)		Lignosus rhinocerotis	AYO51536.1			1
ORF		Linum usitatissimum	AFN53658.1
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50277.1			3
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50278.1			3
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50279.1			3
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50280.1			3
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50281.1			3
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50282.1			3
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50283.1			3
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50284.1			2
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50285.1			3
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50286.1			2
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50287.1			3
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50288.1			3
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50289.1			3
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50290.1			3
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50291.1			3
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50292.1			2
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50293.1			3
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50294.1			2
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50295.1			3
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50296.1			3
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50297.1			3
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50298.1			3
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50299.1			3
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50300.1			3
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50301.1			2
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50302.1			3
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50303.1			3
Laccase (fragment)		Lophodermium sp. ZY-2014	AIJ50304.1			3
laccase		Macrotermes barneyi	AFD33366.1
MARU1_000723		Malassezia arunalokei CBS 13387	WFD14717.1			2
MARU1_001233		Malassezia arunalokei CBS 13387	WFD15217.1
MARU1_001232 (fragment)		Malassezia arunalokei CBS 13387	WFD15216.1
MBRA1_003680 (fragment)		Malassezia brasiliensis CBS 14135	WFC97013.1			2
MCAP1_003382		Malassezia caprae CBS 10434	WFD21125.1			2
MCAP1_003606		Malassezia caprae CBS 10434	WFD21344.1
MCAP1_003606		Malassezia caprae CBS 10434	WFD21344.1
MCAP1_002479		Malassezia caprae CBS 10434	WFD20235.1			2
MCUN1_003176		Malassezia cuniculi CBS 11721	WFD36297.1
MCUN1_000991 (fragment)		Malassezia cuniculi CBS 11721	WFD34155.1
MEQU1_002927		Malassezia equina CBS 12830	WFD24230.1			2
MEQU1_003520		Malassezia equina CBS 12830	WFD24815.1
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