| Activities in Family | Laccase / p-diphenol:oxygen oxidoreductase / ferroxidase (EC 1.10.3.2); ; ferroxidase (EC 1.10.3.-); Laccase-like multicopper oxidase (EC 1.10.3.-) |
|---|---|
| Note | The characterized AA1 enzymes are multicopper oxidases that use diphenols and related substances as donors with oxygen as the acceptor. The AA1 family is currently divided into 3 subfamilies including laccases, ferroxidases and laccase-like multicopper oxidases. |
| Statistics | GenBank accession (4072); Uniprot accession (207); PDB accession (61); 3D entries (22); cryst (0) |
| < | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 32 | > | ||||||
| Eukaryota | ||||||
| Protein Name | EC# | Organism | GenBank | Uniprot | PDB/3D | Subf |
| 0_8531_01 (fragment) | Abies alba | AFB33028.1 AFB33029.1 |
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| secreted protein | Achlya hypogyna ATCC 48635 | AIG56331.1 | ||||
| secreted protein | Achlya hypogyna ATCC 48635 | AIG56347.1 | 2 | |||
| laccase-3 (Lac3) | Actinidia deliciosa | ASL06590.1 | ||||
| laccase-3 variant 2 (Lac3) | Actinidia deliciosa | ASL06592.1 | ||||
| laccase-7 (Lac7) | Actinidia deliciosa | ASL06593.1 | ||||
| laccase 2, partial (fragment) | Aethina tumida | ANW72130.1 | ||||
| laccase (Lcc2) | Agaricus bisporus D649 | AAA17035.1 | Q12542 | 1 | ||
| laccase (Lcc1) | Agaricus bisporus D649 | AAC18877.1 | Q12541 | 1 | ||
| Lcc3 | Agaricus bisporus var. bisporus H97 | ACE73659.1 | 1 | |||
| Lcc2 | Agaricus bisporus var. bisporus H97 | ACZ06558.1 | 1 | |||
| Lcc5 | Agaricus bisporus var. bisporus U1-7 | ACU52699.1 | 1 | |||
| Lcc6 (fragment) | Agaricus bisporus var. bisporus U1-7 | ACZ57763.1 | ||||
| Lcc4 | Agaricus bisporus var. bisporus U1-7 / ATCC 96326 | ACR19861.1 | 1 | |||
| ORF | Agaricus bisporus var. eurotetrasporus ATCC MYA-2386 | ADF45670.1 | 1 | |||
| ORF (fragment) | Agaricus bisporus var. eurotetrasporus ATCC MYA-2386 | AFJ24332.1 | 1 | |||
| ORF | Agaricus bisporus var. eurotetrasporus Bs423 | ADA82243.1 | 1 | |||
| laccase, partial (fragment) | Agaricus blazei U2/4 | AMB72860.1 | 1 | |||
| laccase 1a / lacasse 1b (Lac1A;Lac1B) | Agaricus brasiliensis | BAO09156.1 BAO09157.1 |
1 | |||
| laccase 2a (Lac2A) | Agaricus brasiliensis | BAO09158.1 | 1 | |||
| laccase 2b (Lac2B) | Agaricus brasiliensis | BAO09159.1 | 1 | |||
| laccase 3 (Lac3) | Agaricus brasiliensis | BAO09160.1 | 1 | |||
| laccase 4 (Lac4) | Agaricus brasiliensis | BAO09161.1 | 1 | |||
| multicopper oxidase related protein (McorP) | Anopheles gambiae G3 | AHZ13216.1 | ||||
| laccase 2 (Lac2) | Anopheles sinensis LS-WX | ARG47519.1 | ||||
| laccase 2 (Lac2) | Antheraea pernyi Shenhuang No.2 | AII19522.1 | ||||
| laccase A | Antrodiella faginea | ALE66817.1 | 5DAO[A] 5EHF[A] |
1 | ||
| laccase B | Antrodiella faginea | ALE66818.1 | 1 | |||
| laccase C | Antrodiella faginea | ALE66819.1 | 1 | |||
| laccase C, partial (fragment) | Antrodiella pallasii | AWC08471.1 | 1 | |||
| laccase F, partial (fragment) | Antrodiella pallasii | AWC08474.1 | 1 | |||
| laccase B, partial (fragment) | Antrodiella pallasii | AWC08470.1 | 1 | |||
| laccase E, partial (fragment) | Antrodiella pallasii | AWC08473.1 | 1 | |||
| laccase G, partial (fragment) | Antrodiella pallasii | AWC08476.1 | 1 | |||
| laccase A, partial (fragment) | Antrodiella pallasii | AWC08469.1 | 1 | |||
| laccase H, partial (fragment) | Antrodiella pallasii | AWC08475.1 | 1 | |||
| laccase D, partial (fragment) | Antrodiella pallasii | AWC08472.1 | 1 | |||
| ACCB10298 | Apis cerana | AEY60851.1 | ||||
| laccase-type phenoloxidase 3 | Apostichopus japonicus | ASM47932.1 | ||||
| laccase-type phenoloxidase 2 | Apostichopus japonicus | ASM47931.1 | ||||
| laccase-type phenoloxidase | Apostichopus japonicus | AGR83982.1 | ||||
| ORF (fragment) | Arabidopsis lyrata subsp. lyrata | AFR65246.1 AFR65249.1 AFR65252.1 AFR65253.1 AFR65255.1 AFR65256.1 AFR65261.1 AFR65262.1 AFR65266.1 AFR65275.1 AFR65276.1 |
||||
| ORF (fragment) | Arabidopsis lyrata subsp. lyrata | AFR65269.1 | ||||
| ORF (fragment) | Arabidopsis lyrata subsp. lyrata | AFR65274.1 | ||||
| ORF (fragment) | Arabidopsis lyrata subsp. lyrata | AFR65373.1 AFR65341.1 AFR65363.1 AFR65365.1 AFR65367.1 AFR65371.1 |
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| ORF (fragment) | Arabidopsis lyrata subsp. lyrata | AFR65342.1 | ||||
| Laccase (fragment) | Arabidopsis lyrata subsp. lyrata | AFR65245.1 AFR65267.1 AFR65268.1 AFR65273.1 |
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| Laccase (fragment) | Arabidopsis lyrata subsp. lyrata | AFR65250.1 AFR65254.1 AFR65270.1 |
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| Laccase (fragment) | Arabidopsis lyrata subsp. lyrata | AFR65258.1 AFR65259.1 AFR65260.1 |
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| Laccase (fragment) | Arabidopsis lyrata subsp. lyrata | AFR65248.1 AFR65264.1 AFR65358.1 |
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| Laccase (fragment) | Arabidopsis lyrata subsp. lyrata | AFR65343.1 AFR65345.1 AFR65346.1 AFR65347.1 AFR65348.1 AFR65349.1 AFR65351.1 AFR65355.1 AFR65357.1 AFR65359.1 AFR65364.1 AFR65366.1 AFR65368.1 AFR65369.1 AFR65370.1 AFR65372.1 AFR65374.1 AFR65375.1 AFR65376.1 AFR65377.1 AFR65378.1 AFR65379.1 |
||||
| ORF (fragment) | Arabidopsis lyrata subsp. lyrata | AFR65247.1 AFR65251.1 AFR65257.1 AFR65263.1 AFR65265.1 AFR65271.1 AFR65272.1 AFR65344.1 AFR65350.1 AFR65352.1 AFR65353.1 AFR65354.1 AFR65356.1 AFR65360.1 AFR65361.1 AFR65362.1 AFR65380.1 |
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| ORF (fragment) | Arabidopsis lyrata subsp. petraea | AFR65187.1 AFR65188.1 AFR65189.1 AFR65191.1 AFR65192.1 AFR65193.1 AFR65194.1 AFR65195.1 AFR65196.1 AFR65197.1 AFR65199.1 AFR65200.1 AFR65201.1 AFR65202.1 AFR65203.1 AFR65204.1 AFR65205.1 AFR65206.1 AFR65207.1 AFR65208.1 AFR65209.1 AFR65213.1 AFR65214.1 AFR65215.1 AFR65216.1 |
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| ORF (fragment) | Arabidopsis lyrata subsp. petraea | AFR65190.1 AFR65212.1 AFR65222.1 AFR65224.1 AFR65228.1 AFR65232.1 AFR65236.1 AFR65244.1 AFR65395.1 AFR65397.1 AFR65403.1 AFR65404.1 AFR65405.1 AFR65406.1 AFR65428.1 AFR65430.1 AFR65459.1 AFR65460.1 AFR65463.1 AFR65464.1 AFR65465.1 AFR65466.1 AFR65467.1 AFR65468.1 AFR65469.1 AFR65470.1 AFR65471.1 AFR65472.1 AFR65473.1 AFR65477.1 |
||||
| ORF (fragment) | Arabidopsis lyrata subsp. petraea | AFR65198.1 AFR65210.1 AFR65211.1 |
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| ORF (fragment) | Arabidopsis lyrata subsp. petraea | AFR65230.1 AFR65234.1 |
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| ORF (fragment) | Arabidopsis lyrata subsp. petraea | AFR65277.1 AFR65278.1 AFR65279.1 AFR65280.1 AFR65283.1 AFR65284.1 AFR65285.1 AFR65287.1 AFR65288.1 AFR65289.1 AFR65291.1 AFR65293.1 AFR65295.1 AFR65297.1 AFR65299.1 AFR65300.1 AFR65301.1 AFR65303.1 AFR65305.1 AFR65306.1 AFR65307.1 |
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| ORF (fragment) | Arabidopsis lyrata subsp. petraea | AFR65281.1 AFR65282.1 AFR65286.1 AFR65290.1 AFR65292.1 AFR65294.1 AFR65296.1 AFR65298.1 AFR65302.1 AFR65304.1 AFR65308.1 |
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| ORF (fragment) | Arabidopsis lyrata subsp. petraea | AFR65312.1 AFR65314.1 |
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| ORF (fragment) | Arabidopsis lyrata subsp. petraea | AFR65318.1 AFR65320.1 AFR65322.1 AFR65328.1 AFR65334.1 AFR65336.1 |
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| ORF (fragment) | Arabidopsis lyrata subsp. petraea | AFR65381.1 AFR65383.1 AFR65389.1 AFR65393.1 |
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| ORF (fragment) | Arabidopsis lyrata subsp. petraea | AFR65382.1 | ||||
| ORF (fragment) | Arabidopsis lyrata subsp. petraea | AFR65384.1 | ||||
| Laccase (fragment) | Arabidopsis lyrata subsp. petraea | AFR65407.1 | ||||
| ORF (fragment) | Arabidopsis lyrata subsp. petraea | AFR65411.1 | ||||
| ORF (fragment) | Arabidopsis lyrata subsp. petraea | AFR65385.1 AFR65390.1 AFR65391.1 AFR65392.1 AFR65409.1 AFR65410.1 AFR65412.1 AFR65413.1 |
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| Laccase (fragment) | Arabidopsis lyrata subsp. petraea | AFR65415.1 AFR65416.1 AFR65420.1 |
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| ORF (fragment) | Arabidopsis lyrata subsp. petraea | AFR65419.1 | ||||
| ORF (fragment) | Arabidopsis lyrata subsp. petraea | AFR65330.1 AFR65332.1 AFR65338.1 AFR65421.1 AFR65423.1 AFR65424.1 AFR65425.1 AFR65431.1 AFR65433.1 AFR65437.1 AFR65439.1 AFR65440.1 AFR65441.1 AFR65445.1 AFR65446.1 AFR65447.1 AFR65448.1 AFR65449.1 AFR65450.1 AFR65451.1 AFR65452.1 AFR65453.1 AFR65454.1 AFR65455.1 AFR65456.1 AFR65462.1 AFR65474.1 AFR65478.1 |
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| Laccase (fragment) | Arabidopsis lyrata subsp. petraea | AFR65394.1 AFR65398.1 AFR65401.1 |
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| Laccase (fragment) | Arabidopsis lyrata subsp. petraea | AFR65217.1 AFR65218.1 AFR65219.1 AFR65220.1 AFR65221.1 AFR65223.1 AFR65225.1 AFR65226.1 AFR65227.1 AFR65229.1 AFR65231.1 AFR65233.1 AFR65235.1 AFR65237.1 AFR65238.1 AFR65239.1 AFR65240.1 AFR65241.1 AFR65242.1 AFR65243.1 AFR65309.1 AFR65310.1 AFR65311.1 AFR65313.1 AFR65315.1 AFR65316.1 AFR65317.1 AFR65319.1 AFR65321.1 AFR65323.1 AFR65324.1 AFR65325.1 AFR65326.1 AFR65327.1 AFR65329.1 AFR65331.1 AFR65333.1 AFR65335.1 AFR65337.1 AFR65339.1 AFR65340.1 AFR65386.1 AFR65387.1 AFR65388.1 AFR65396.1 AFR65399.1 AFR65400.1 AFR65402.1 AFR65414.1 AFR65418.1 AFR65422.1 AFR65426.1 AFR65427.1 AFR65429.1 AFR65432.1 AFR65434.1 AFR65435.1 AFR65436.1 AFR65438.1 AFR65442.1 AFR65443.1 AFR65444.1 AFR65457.1 AFR65458.1 AFR65461.1 AFR65475.1 AFR65476.1 |
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| Laccase (fragment) | Arabidopsis lyrata subsp. petraea | AFR65408.1 AFR65417.1 |
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| laccase, partial (LcC) (fragment) | Arthopyrenia sp. CBMAI 1330 | AJZ68867.1 | 3 | |||
| EGX46921.1 | Arthrobotrys oligospora ATCC 24927 | 2 | ||||
| EGX44960.1 | Arthrobotrys oligospora ATCC 24927 | |||||
| EGX52908.1 | Arthrobotrys oligospora ATCC 24927 | |||||
| laccase, partial (fragment) | Aspergillus flavus NG85 | AIT97143.2 | ||||
| ferroxidase (FetC) | Aspergillus fumigatus | AAT84595.1 | 2 | |||
| pigment biosynthesis protein brown 1 (Abr1) (partial) | Aspergillus fumigatus IHEM 9860 | ACJ13061.1 | 2 | |||
| pigment biosynthesis protein brown 1 (Abr1) | Aspergillus fumigatus NCPF 7760 | AHA42448.1 | ||||
| pigment biosynthesis protein brown 1 (Abr1) | Aspergillus fumigatus UA 110325149 | AHA42447.1 | ||||
| lac c protein, partial (fragment) | Aspergillus nidulans | AWI47683.1 | 3 | |||
| lac b protein, partial (fragment) | Aspergillus nidulans | AWI47682.1 | 3 | |||
| lac d protein, partial (fragment) | Aspergillus nidulans | AWI47684.1 | ||||
| AN9170.2 | Aspergillus nidulans FGSC A4 | EAA61461.1 | C8VK20 | 3 | ||
| AN5397.2 | Aspergillus nidulans FGSC A4 | EAA62557.1 | C8VGM6 | 3 | ||
| An01g00860 (McoN) (probable frameshift) | Aspergillus niger CBS 513.88 | CAK43464.1 | 3 | |||
| An01g08960 (McoH) | Aspergillus niger CBS 513.88 | CAK37140.1 XP_001389317.1 |
A2Q9S8 | 2 | ||
| An15g05520 (McoK) | Aspergillus niger CBS 513.88 | CAK97337.1 | 2 | |||
| An11g03580 (McoD) | Aspergillus niger CBS 513.88 | CAK48347.1 | A2QW24 | 3 | ||
| An16g02020 (McoM) | Aspergillus niger CBS 513.88 | CAL00426.1 XP_001397515.1 |
A2R723 | 3 | ||
| An18g02690 (McoI) | Aspergillus niger CBS 513.88 | CAK48652.1 XP_001398728.1 |
A2RAC6 | 3 | ||
| laccase (McoG;An08g08450) | 1.10.3.2 | Aspergillus niger CBS 513.88 | CAK40046.1 | A2QS62 | 5LM8[A] 5LWW[A] 5LWX[A] |
3 |
| An12g05810 (McoJ) | Aspergillus niger CBS 513.88 | CAK46289.1 XP_001395646.1 |
A2QZQ7 | 3 | ||
| An05g02340 (McoF) | Aspergillus niger CBS 513.88 | CAK44895.1 XP_001390802.1 |
A2QL29 | 3 | ||
| An01g14010 (McoA) | Aspergillus niger CBS 513.88 | CAK37405.1 | ||||
| An01g13660 (McoB;yA) | Aspergillus niger CBS 513.88 | CAK37372.1 | ||||
| An03g03750 (McoC) | Aspergillus niger CBS 513.88 | CAK47814.1 | ||||
| An01g11120 (McoE) | Aspergillus niger CBS 513.88 | CAK44017.1 | ||||
| An14g05370 (BrnA) | Aspergillus niger CBS 513.88 | CAK42098.1 | 2 | |||
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