Activities in Family	[copper-containing] dihydrogeodin oxidase (EC 1.10.3.-); Laccase / p-diphenol:oxygen oxidoreductase (EC 1.10.3.2);
Note	The characterized AA1 enzymes are multicopper oxidases that use diphenols and related substances as donors with oxygen as the acceptor. The AA1 family is currently divided into 3 subfamilies including laccases, ferroxidases and laccase-like multicopper oxidases.
Statistics	GenBank accession (8043); Uniprot accession (80); PDB accession (91); 3D entries (27); cryst (0)

Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Resolution (Å)	Subf
laccase A		Antrodiella faginea	ALE66817.1		5DAO[A] 1.75 5EHF[A] 1.75	1
laccase (McoG;An08g08450)		Aspergillus niger CBS 513.88	CAK40046.1	A2QS62	5LM8[A] 1.70 5LWW[A] 2.65 5LWX[A] 1.49	3
Laccase		Aspergillus oryzae			6H5Y[B] 2.30 6H5Y[A] 2.30	1
laccase		basidiomycete PM1 PM1(CECT 2971)	CAA78144.1	Q12571	5ANH[A,B,C] 2.49	1
laccase (Lac;BaLac)		Botrytis aclada DSMZ 62081	AFC76164.1	H8ZRU2	3SQR[A] 1.67 3V9E[A] 1.70 4X4K[A] 2.30	3
laccase 2 (Lac2;T2D)		Cerrena caperata	AGE13770.1		4JHU[A] 1.89 4JHV[A] 1.60	1
laccase 7		Cerrena sp. RSD1			5Z1X[B] 1.38 5Z22[A] 1.50 5Z1X[A] 1.38	1
laccase 1 (Lcc1)		Coprinopsis cinerea A3387	AAD30964.1	Q9Y780	1A65[A] 2.23 1HFU[A] 1.68	1
laccase (Lac1)		Coriolopsis gallica SAH-12	ABD93940.1 ABD93941.1	Q1W6B1	4A2D[A] 2.30 4A2E[A] 1.80 4A2F[A] 1.90 4A2G[A] 1.80 4A2H[A] 2.30 5A7E[A] 1.50	1
laccase (Lcc4)		Lentinus sp. WR2	AIT51846.1	A0A0F6NTZ1	3X1B[A,B] 1.80	1
laccase (Lcc1) (fragment)		Lentinus tigrinus	AAX07469.1		2QT6[A,B] 1.50	1
laccase (Lac1)		Melanocarpus albomyces	CAE00180.1	Q70KY3	1GW0[A,B] 2.4 2IH8[A,B] 2.00 2IH9[A,B] 2.00 2Q9O[A,B] 1.30 3DKH[A,B] 2.40 3FU7[A,B] 1.67 3FU8[A,B] 1.80 3FU9[A,B] 2.00	3
laccase BP76		Neocapritermes taracua	ALQ52760.1		8R7I[A]
laccase		Rigidoporus microporus	CAE81289.1	Q6H9H7	1V10[A] 1.7	1
multicopper oxidase (Fet3)		Saccharomyces cerevisiae	AAA64929.1		1ZPU[A,B,C,D,E,F] 2.80	2
laccase 2		Steccherinum murashkinskyi	AFI41889.1	I1VE66	5E9N[A] 0.95 5MEJ[A] 1.50 5MEW[A] 1.35 5MHU[A] 1.35 5MHV[A] 1.35 5MHW[A] 1.35 5MHX[A] 1.35 5MHY[A] 1.35 5MHZ[A] 1.35 5MI1[A] 1.35 5MI2[A] 1.35 5MIA[A] 1.35 5MIB[A] 1.35 5MIC[A] 1.35 5MID[A] 1.35 5MIE[A] 1.35 5MIG[A] 1.35 6RGH[A] 1.08 6RGP[A] 0.97 6RHH[A] 0.97 6RHI[A] 1.01 6RHO[A] 1.07 6RHP[A] 1.60 6RHR[A] 1.06 6RHU[A] 0.96 6RHX[A] 0.96 6RI0[A] 1.00 6RI2[A] 1.09 6RI4[A] 1.08 6RI6[A] 0.93 6RI8[A] 0.95 6RII[A] 0.97 6RIK[A] 1.20 6RIL[A] 1.34	1
blue laccase		Steccherinum ochraceum			3T6V[B,C] 2.00 3T6W[A,B,C] 2.15 3T6X[A,B,C] 2.15 3T6Z[A,B,C] 2.15 3T71[A,B,C] 2.15 3T6V[A] 2.00	1
laccase (MYCTH_2063133;Lmco1)		Thermothelomyces thermophilus ATCC 42464	G2QFD0.1		7ZN6[A] 1.90
laccase (Lcc1; MYCTH_51627)		Thermothelomyces thermophilus ATCC 42464	XP_003663741.1	G2QG31	6F5K[A] 1.62	3
laccase (Lcc1;TaLcc1)		Thielavia arenaria	333361328	F6N9E7	3PPS[A,B,C,D] 2.50	3
laccase (Lcc1)		Trametes coccinea M85-2	BAB69775.1 BAB69776.1	Q96TR6 Q96VA5	5NQ8[A] 2.00	1
laccase (Lac)		Trametes hirsuta	ACC43989.1 AAL89554.2		3FPX[A] 1.80 3PXL[A] 1.20 3V9C[A] 2.00	1
laccase A		Trametes hirsuta	AIZ72721.1		5LDU[A] 2.30	1
laccase		Trametes sanguinea BRFM 902	ACZ37083.1	D7F485	5NQ7[A] 2.75	1
laccase I (LccI;Lcc2)		Trametes versicolor 52J	AAA86659.1 AAC49828.1	Q12718	1GYC[A] 1.9	1
laccase B (Lac1)		Trametes versicolor ATCC 32745	AAL07440.1	Q96UT7	1KYA[A,B,C,D] 2.40	1
unknown (fragment)		Zea mays B73	ACF79418.1	B4FBC5	6KLG[A] 2.10 6KLI[A] 1.80 6KLJ[A] 2.00
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