Mechanism	Inverting e
Clan	GH-I
3D Structure Status	lysozyme fold
Catalytic Nucleophile/Base	Not known
Catalytic Proton Donor	Glu
External resources	CAZypedia; PRINTS;
Statistics	GenBank accession (29914); Uniprot accession (25); PDB accession (686); 3D entries (17); cryst (1)

Bacteria
Protein Name	EC#	Reference	Organism	GenBank	Uniprot	PDB/3D
muramidase (SpmX; EM6_0389)	3.2.1.17	pubmed	Asticcacaulis excentricus M6	BBF79816.1	A0A3G9FZN7	6H9D[A,B,C]
muramidase (SpmX; CC2173)	3.2.1.17	pubmed	Caulobacter vibrioides CB15	AAK24144.1 NP_420976.1	Q9A6C1
lysozyme (DLP12;b0555;EO53_15490)	3.2.1.17	pubmed	Escherichia coli str. K-12 substr. MG1655	AIZ92304.1 AAB40751.1 AAC73656.1 ALI41640.1 AMC97790.1 AUG15343.1 AVI55088.1 AYG20320.1	P78285	4ZPU[A,B,C,D]
peptidoglycan endo-β-1,4-N-acetylmuramidase (PSPA7_0693)	3.2.1.17	pubmed	Pseudomonas paraeruginosa PA7	ABR86835.1	A6UZ53
Eukaryota
Protein Name	EC#	Reference	Organism	GenBank	Uniprot	PDB/3D
muramidase	3.2.1.17	pubmed	Chaetomium sp. ZY287	WJZ50381.1
muramidase	3.2.1.17	pubmed	Geomyces auratus	WJZ50384.1
muramidase	3.2.1.17	pubmed	Ilyonectria rufa	WJZ50385.1
muramidase	3.2.1.17	pubmed	Metarhizium sp. XZ2431	WJZ50383.1
muramidase	3.2.1.17	pubmed	Mortierella sp. ZY002	WJZ50382.1
muramidase	3.2.1.17	pubmed	Thermochaetoides thermophila	WJZ50378.1
muramidase	3.2.1.17	pubmed	Trichoderma harzianum	WJZ50379.1
muramidase	3.2.1.17	pubmed	Trichophaea minuta	WJZ50380.1
muramidase (TsCWBD-GH24)	3.2.1.17	pubmed	Trichophaea saccata CBS804.70	WJZ50377.1	A0AA82WPD1	8B2S[A,B]
Viruses
Protein Name	EC#	Reference	Organism	GenBank	Uniprot	PDB/3D
endolysin	3.2.1.17	pubmed	Acinetobacter phage AbTZA1	AZU98615.1	A0A3T0IGR7	8APP[A,B,C,D]
peptidoglycan endo-β-1,4-N-acetylmuramidase (Era103g49)	3.2.1.17	pubmed	Erwinia phage Era103	ABM63439.1	A2I817
lysozyme	3.2.1.17	pubmed	Erwinia phage phi-Ea1h	CAC17007.1	Q9FZS7
lysozyme (ECTP15_02508;RrrD)	3.2.1.17	pubmed	Escherichia coli O157 typing phage 15	AKE47249.1	A0A0F6R9G3	7M5I[A,B]
lysozyme	3.2.1.17	pubmed	Lactococcus phage phi-vML3	CAA34300.1	P13003 P62693
lysozyme (P22Lyso)	3.2.1.17	pubmed	Lederbergvirus P22 ATCC 19585-B1	AAA32266.1 AAA88340.1 AAF75040.1 AAM81442.1 BAF80780.1 DAA01040.1 NP_059622.1	A8CGF4 P09963 P09963	2ANV[A,B] 2ANX[A,B]
Lys	3.2.1.17	pubmed	Muvirus mu	AAF01099.1 NP_050626.1	Q9T1X2
lysozyme (LysA;Liz;Gp17)	3.2.1.17	pubmed	Punavirus P1	AAD20630.1 AAQ13989.1 AAQ14097.1 CAA61013.1	Q37875 Q71TF3	1XJT[A] 1XJU[A,B]
endolysin 68 (Lys68)	3.2.1.17	pubmed	Salmonella phage phi68	AHY18890.1	A0A023VTC7
endolysin (LysSP1)	3.2.1.17	pubmed	Salmonella phage SLMP1	QXP00517.1	A0A8F5VS41
tail-associated lysozyme (Gp5)	3.2.1.17	pubmed	Tequatrovirus T4	AAD42482.1 CAA33749.1 NP_049757.1 QPI17370.1	A0A7S9SVH6 D9IEH9 P16009	1K28[A] 1PDL[A,B,C] 1WTH[A] 2Z6B[A]
lysozyme E (T4L;T4p123)	3.2.1.17	pubmed	Tequatrovirus T4	AAD42568.1 CAA28212.1 NP_049736.1	D9IEF7 D9IEF7 P00720	102L[A] 103L[A] 104L[A,B] 107L[A] 108L[A] 109L[A] 110L[A] 111L[A] 112L[A] 113L[A] 114L[A] 115L[A] 118L[A] 119L[A] 120L[A] 122L[A] 123L[A] 125L[A] 126L[A] 127L[A] 128L[A] 129L[A] 130L[A] 131L[A] 137L[A,B] 138L[A] 139L[A] 140L[A] 141L[A] 142L[A] 143L[A] 144L[A] 145L[A] 146L[A] 147L[A] 148L[E] 149L[A] 150L[A,B,C,D] 151L[A] 152L[A] 155L[A] 156L[A] 157L[A] 158L[A] 159L[A] 160L[A] 161L[A] 162L[A] 163L[A] 164L[A] 165L[A] 166L[A] 167L[A,B] 168L[A,B,C,D,E] 169L[A,B,C,D,E] 170L[A] 171L[A] 172L[A] 173L[A] 174L[A,B] 175L[A,B] 176L[A,B] 177L[A] 178L[A] 179L[A] 180L[A] 181L[A] 182L[A] 183L[A] 184L[A] 185L[A] 186L[A] 187L[A] 188L[A] 189L[A] 190L[A] 191L[A] 192L[A] 195L[A] 196L[A] 197L[A] 198L[A] 199L[A] 1B6I[A] 1C60[A] 1C61[A] 1C62[A] 1C63[A] 1C64[A] 1C65[A] 1C66[A] 1C67[A] 1C68[A] 1C69[A] 1C6A[A] 1C6B[A] 1C6C[A] 1C6D[A] 1C6E[A] 1C6F[A] 1C6G[A] 1C6H[A] 1C6I[A] 1C6J[A] 1C6K[A] 1C6L[A] 1C6M[A] 1C6N[A] 1C6P[A] 1C6Q[A] 1C6T[A] 1CTW[A] 1CU0[A] 1CU2[A] 1CU3[A] 1CU5[A] 1CU6[A] 1CUP[A] 1CUQ[A] 1CV0[A] 1CV1[A] 1CV3[A] 1CV4[A] 1CV5[A] 1CV6[A] 1CVK[A] 1CX6[A] 1CX7[A] 1D2W[A] 1D2Y[A] 1D3F[A] 1D3J[A] 1D3M[A] 1D3N[A] 1D9W[A] 1DYA[A] 1DYB[A] 1DYC[A] 1DYD[A] 1DYE[A] 1DYF[A] 1DYG[A] 1EPY[A] 1G06[A] 1G07[A] 1G0G[A] 1G0J[A] 1G0K[A] 1G0L[A] 1G0M[A] 1G0P[A] 1G0Q[A] 1JOZ[A] 1JQU[A,B,C,D] 1JTM[A] 1JTN[A,B] 1KNI[A] 1KS3[A] 1KW5[A] 1KW7[A] 1KY0[A] 1KY1[A] 1L00[A] 1L01[A] 1L02[A] 1L03[A] 1L04[A] 1L05[A] 1L06[A] 1L07[A] 1L08[A] 1L09[A] 1L0J[A] 1L0K[A] 1L10[A] 1L11[A] 1L12[A] 1L13[A] 1L15[A] 1L16[A] 1L17[A] 1L18[A] 1L19[A] 1L20[A] 1L21[A] 1L22[A] 1L23[A] 1L24[A] 1L25[A] 1L26[A] 1L27[A] 1L28[A] 1L29[A] 1L30[A] 1L31[A] 1L32[A] 1L33[A] 1L34[A] 1L35[A] 1L36[A] 1L37[A] 1L38[A] 1L39[A] 1L40[A] 1L41[A] 1L42[A] 1L43[A] 1L44[A] 1L45[A] 1L46[A] 1L47[A] 1L48[A] 1L49[A] 1L50[A] 1L51[A] 1L52[A] 1L53[A] 1L54[A] 1L55[A] 1L56[A] 1L57[A] 1L58[A] 1L59[A] 1L60[A] 1L61[A] 1L62[A] 1L63[A] 1L64[A] 1L65[A] 1L66[A] 1L67[A] 1L68[A] 1L69[A] 1L70[A] 1L71[A] 1L72[A] 1L73[A] 1L74[A] 1L75[A] 1L76[A] 1L77[A] 1L79[A] 1L80[A] 1L81[A] 1L82[A] 1L83[A] 1L84[A] 1L85[A] 1L86[A] 1L87[A] 1L88[A] 1L89[A] 1L90[A] 1L91[A] 1L92[A] 1L93[A] 1L94[A] 1L95[A] 1L96[A] 1L97[A,B] 1L98[A] 1L99[A] 1LGU[A] 1LGW[A] 1LGX[A] 1LI2[A] 1LI3[A] 1LI6[A] 1LLH[A] 1LPY[A] 1LW9[A] 1LWG[A] 1LWK[A] 1LYD[A] 1LYE[A] 1LYF[A] 1LYG[A] 1LYH[A] 1LYI[A] 1LYJ[A] 1NHB[A] 1OV5[A] 1OV7[A] 1OVH[A] 1OVJ[A] 1OVK[A] 1OWY[A] 1OWZ[A] 1P2L[A] 1P2R[A] 1P37[A] 1P46[A] 1P56[A] 1P5C[A,B,C,D] 1P64[A] 1P6Y[A] 1P7S[A] 1QS5[A] 1QS9[A] 1QSB[A] 1QSQ[A] 1QT3[A] 1QT4[A] 1QT5[A] 1QT6[A] 1QT7[A] 1QT8[A] 1QTB[A] 1QTC[A] 1QTD[A] 1QTH[A,B] 1QTV[A] 1QTZ[A] 1QUD[A] 1QUG[A] 1QUH[A] 1QUO[A] 1SWY[A] 1SWZ[A] 1SX2[A] 1SX7[A] 1T6H[A] 1T8A[A] 1T97[A,B] 1TLA[A] 1XEP[A] 1ZUR[A] 1ZWN[A] 1ZYT[A] 200L[A] 201L[A,B] 205L[A] 206L[A] 209L[A] 210L[A] 211L[A] 212L[A] 213L[A] 214L[A] 215L[A] 216L[A,B] 217L[A] 218L[A] 219L[A] 220L[A] 221L[A] 222L[A] 223L[A] 224L[A] 225L[A] 226L[A] 227L[A] 228L[A] 229L[A] 230L[A] 231L[A] 232L[A] 233L[A] 234L[A] 235L[A] 236L[A] 237L[A] 238L[A] 239L[A] 240L[A] 241L[A] 242L[A] 243L[A] 244L[A] 245L[A] 246L[A] 247L[A] 248L[A] 249L[A] 250L[A] 251L[A] 252L[A] 253L[A] 254L[A] 255L[A] 256L[A] 257L[A] 258L[A] 259L[A] 260L[A] 261L[A] 262L[A,B] 2A4T[A] 2B6T[A] 2B6W[A] 2B6X[A] 2B6Y[A] 2B6Z[A] 2B70[A] 2B72[A] 2B73[A] 2B74[A] 2B75[A] 2B7W[A,B,C,D] 2B7X[A,B,C,D] 2CUU[A] 2F2Q[A] 2F32[A] 2F47[A] 2HUK[A] 2HUL[A] 2HUM[A,B] 2IGC[A] 2L78[A] 2LC9[A] 2LCB[A] 2LZM[A] 2NTG[A] 2NTH[A] 2NZB[A] 2NZK[A] 2NZN[A] 2O4W[A] 2O79[A] 2OE4[X] 2OE7[X] 2OE9[X] 2OEA[X] 2OTY[X] 2OTZ[X] 2OU0[X] 2OU8[A] 2OU9[A] 2Q9D[A] 2Q9E[A,B,C] 2QAR[C,F] 2QB0[B,D] 2RAY[X] 2RAZ[X] 2RB0[X] 2RB1[X] 2RB2[X] 2RBN[A] 2RBO[A] 2RBP[A] 2RBQ[A] 2RBR[A] 2RBS[A] 2RH1[A] 3C7W[A] 3C7Y[A] 3C7Z[A] 3C80[A] 3C81[A] 3C82[A] 3C83[A] 3C8Q[A] 3C8R[A] 3C8S[A] 3CDO[A,B,C,D] 3CDQ[A] 3CDR[A] 3CDT[A] 3CDV[A] 3D4S[A] 3DKE[X] 3DMV[A] 3DMX[A] 3DMZ[A] 3DN0[A] 3DN1[A] 3DN2[A] 3DN3[A] 3DN4[A] 3DN6[A] 3DN8[A] 3DNA[A] 3EML[A] 3F8V[A] 3F9L[A] 3FA0[A] 3FAD[A] 3FI5[A,B,C,D] 3G3V[A] 3G3W[A] 3G3X[A] 3GUI[A] 3GUJ[A] 3GUK[A,B] 3GUL[A,B] 3GUM[A,B] 3GUN[A,B] 3GUO[A,B] 3GUP[A,B] 3HH3[A] 3HH4[A] 3HH5[A] 3HH6[A] 3HT6[A] 3HT7[A] 3HT8[A] 3HT9[A] 3HTB[A] 3HTD[A] 3HTF[A] 3HTG[A] 3HU8[A] 3HU9[A] 3HUA[A] 3HUK[A] 3HUQ[A] 3HWL[A] 3JR6[A,B,C,D] 3K2R[A] 3L2X[A] 3L64[A] 3LZM[A] 3NY8[A] 3ODU[A,B] 3OE0[A] 3OE6[A] 3OE8[A,B,C] 3OE9[A,B] 3P0G[A] 3PBL[A,B] 3PDS[A] 3QAK[A] 3RUN[A] 3RZE[A] 3SB5[A,B,C,D] 3SB6[A,B] 3SB7[A,B] 3SB8[A,B,C] 3SB9[A,B] 3SBA[A,B,C,D,E,F] 3SBB[C] 3UON[A] 3V2W[A] 3V2Y[A] 3VW7[A] 4ARJ[A,B] 4DAJ[A,B,C,D] 4DJH[A,B] 4DKL[A] 4E97[A,B] 4EJ4[A] 4EKP[A,B] 4EKQ[A,B] 4EKR[A,B] 4EKS[A,B] 4EPI[A] 4EXM[A,B,C,D] 4GBR[B] 4GRV[A] 4HTT[A,B] 4I7J[A,B] 4I7K[A,B] 4I7L[A,B] 4I7M[A,B] 4I7N[A,B] 4I7O[A,B] 4I7P[A,B] 4I7Q[A,B] 4I7R[A,B] 4I7S[A,B] 4I7T[A,B] 4IAP[A,B] 4K5Y[A,B,C] 4LDE[A] 4LDL[A] 4LDO[A] 4LZM[A] 4N9N[A,B] 4OO9[A] 4PHU[A] 4PJZ[A] 4PK0[A] 4PLA[A] 4QKX[A] 4RWS[A] 4S0W[A,B] 4U14[A] 4U15[A,B] 4U16[A,B] 4W51[A] 4W52[A] 4W53[A] 4W54[A] 4W55[A] 4W56[A] 4W57[A] 4W58[A] 4W59[A] 4W8F[A,B] 4WTV[A,B] 4XEE[A] 4XES[A] 4YC4[A] 4YX7[C,F] 4YXA[C,F] 4YXC[A] 5CXV[A] 5D5A[A] 5D5B[A] 5DGY[A,B,C,D] 5DSG[A,B] 5EE7[A] 5EUT[A] 5EWX[A,B] 5G27[A] 5I0N[A] 5I14[A,B] 5JDT[A] 5JGN[A] 5JGR[A] 5JGU[A] 5JGV[A] 5JGX[A] 5JGZ[A] 5JWS[A] 5JWT[A] 5KGR[A] 5KHZ[A] 5KI1[A] 5KI2[A] 5KI3[A] 5KI8[A] 5KIG[A] 5KII[A] 5KIM[A] 5KIO[A] 5LWO[A] 5LZM[A] 5NDD[A] 5NDZ[A] 5V7D[A] 5V7E[A] 5V7F[A] 5V83[A] 5V86[A] 5V88[A] 5VEW[A,B] 5VEX[A,B] 5VNQ[A] 5VNR[A] 5XEZ[A,B] 5XF1[A,B] 5XPE[A] 5XPF[A] 6LZM[A] 6PGY[A] 6U0B[A] 6U0C[A] 6U0E[A] 6U0F[A] 6V51[A] 7DWS[A,B,C] 7LOA[A] 7LOB[A] 7LOC[A] 7LOD[A] 7LOE[A] 7LOF[A] 7LOJ[A] 7LX6[A] 7LX7[A] 7LX8[A] 7LX9[A] 7LZM[A]
lysozyme (Lys411)	3.2.1.17	pubmed	Xanthomonas phage Xo411	ABD72265.1 ABK00175.1	A1BPG9 A5H1N1
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