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Polysaccharide Lyase Family 8

Activities in FamilyExo-β-1,4-glucuronan lyase (EC 4.2.2.-);
Exo-hyaluronate lyase (EC 4.2.2.-);
Hyaluronate lyase (EC 4.2.2.1);
Xanthan lyase (EC 4.2.2.12);
Chondroitinase B (EC 4.2.2.19);
Poly(β-mannuronate) lyase / M-specific alginate lyase (EC 4.2.2.3);
Chondroitin AC lyase (EC 4.2.2.5);
Heparin lyase / heparin lyase I (EC 4.2.2.7);
Mechanism b-elimination
3D Structure Status( α / α ) 6 toroid + anti-parallel β-sheet
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (4807); Uniprot accession (30); PDB accession (54); 3D entries (13); cryst (1)
Summary
Download PL8 (5166) Taxonomic display Structure (13 - 1 cryst) Characterized (33)
| 1 | ... | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | ... | 47 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 HW566_14110   Microbacterium oleivorans I46 QLD12808.1    
 P6897_11035   Microbacterium sp. BDGP8 WHE35229.1    
 LQ938_01530   Microbacterium sp. cx-55 UGB35505.1    
 MNR00_16720   Microbacterium sp. H1-D42 UNK70775.1    
 MNR00_02150   Microbacterium sp. H1-D42 UNK71278.1     2
 glycosaminoglycan lyase   Microbacterium sp. H14 QGL52623.1    
 L2X99_17195   Microbacterium sp. KUDC0406 UJP10061.1    
 L2X99_09660   Microbacterium sp. KUDC0406 UJP08781.1    
 PGB26_09015   Microbacterium sp. nov. GSS16 WCD91821.1     2
 KV396_07850   Microbacterium sp. SSW1-36 UPL14390.1    
 xanthan lyase (AB663_001102) 4.2.2.12 Microbacterium sp. XT11 ALX66168.1    
 MTES_2849   Microbacterium testaceum StLB037 BAJ75813.1    
 FOE78_16715   Microlunatus elymi KUDC0627 QDP97345.1    
 SAMN04489812_4258   Microlunatus soli DSM 21800 SDT13119.1    
 QU516_11140   Moellerella wisconsensis NX2019MW WJW81194.1     2
 QU516_11145   Moellerella wisconsensis NX2019MW WJW81195.1     2
 QU516_01525   Moellerella wisconsensis NX2019MW WJW82169.1    
 MNY70_11930   Moellerella wisconsensis W1 UNH38186.1     2
 MNY70_11925   Moellerella wisconsensis W1 UNH38185.1     2
 MNY70_01545   Moellerella wisconsensis W1 UNH39195.1    
 MNY68_11620   Moellerella wisconsensis W17-3 UNH23464.1     2
 MNY68_11625   Moellerella wisconsensis W17-3 UNH23465.1     2
 MNY68_01520   Moellerella wisconsensis W17-3 UNH24471.1    
 MNY64_11855   Moellerella wisconsensis W18-2 UNH26544.1     2
 MNY64_01620   Moellerella wisconsensis W18-2 UNH27575.1    
 MNY64_11860   Moellerella wisconsensis W18-2 UNH26545.1     2
 MNY72_11430   Moellerella wisconsensis W51 UNH29961.1     2
 MNY72_11425   Moellerella wisconsensis W51 UNH29960.1     2
 MNY72_01595   Moellerella wisconsensis W51 UNH31049.1    
 MNY66_01525   Moellerella wisconsensis W65 UNH42717.1    
 MNY66_11580   Moellerella wisconsensis W65 UNH41681.1     2
 MNY66_11575   Moellerella wisconsensis W65 UNH41680.1     2
 HQ865_05340   Mucilaginibacter mali G2-14 QKJ29199.1    
 HQ865_11825   Mucilaginibacter mali G2-14 QKJ30415.1    
 HQ865_05360   Mucilaginibacter mali G2-14 QKJ29203.1    
 MCRO_0392   Mycoplasma crocodyli MP145 ADE19838.1    
 MFE_04780   Mycoplasmopsis fermentans JER ADN69073.1    
 MfeM64YM_0614   Mycoplasmopsis fermentans M64 ADV34612.1    
 NCTC10117_01915   Mycoplasmopsis fermentans NCTC10117 VEU63916.1    
 MBIO_0039   Mycoplasmopsis fermentans PG18 BAH69304.1    
 NCTC10183_00193   Mycoplasmopsis gallinacea NCTC10183 VEU58436.1    
 GOQ20_04330   Mycoplasmopsis gallinacea Peacock20181011 QIW62608.1    
 BLA55_00250   Mycoplasmopsis pullorum B359_6 APJ38126.1    
 hyaluronate lyase (BniHL)   Neobacillus niacini F8 BAO57293.1    
 QNH29_23550   Neobacillus sp. DY30 WHX99532.1    
 A8C56_12645   Niabella ginsenosidivorans BS26 ANH81716.1    
 A8C56_05425   Niabella ginsenosidivorans BS26 ANH80504.1     2
 NIASO_15730   Niabella soli DSM 19437 AHF16211.1     2
 NIASO_08255   Niabella soli DSM 19437 AHF15153.1    
 heparinase (Hep) 4.2.2.7 Niallia circulans BAB91369.1 Q8KKH9   2
 HLK66_10555   Niallia circulans GN03 QJX62049.1    
 C2I06_04330   Niallia circulans PK3_109 AYV66165.1    
 C2H98_05220   Niallia circulans PK3_138 AYV71019.1    
 C2I17_01805   Niallia circulans PK3_15 UQZ73390.1    
 Niako_2983   Niastella koreensis GR20-10 AEV99313.1     3
 Nocox_38355 (Xly2)   Nonomuraea coxensis DSM 45129 QYC45221.1    
 Nocox_19595 (Xly1)   Nonomuraea coxensis DSM 45129 QYC41528.1    
 Nocox_41810 (Xly4)   Nonomuraea coxensis DSM 45129 QYC45903.1    
 OIE67_23030   Nonomuraea fuscirosea NBC 01801 WSA57382.1    
 OIE67_46880   Nonomuraea fuscirosea NBC 01801 WSA51496.1    
 OIE67_54920   Nonomuraea fuscirosea NBC 01801 WSA52986.1    
 OIE67_52615   Nonomuraea fuscirosea NBC 01801 WSA58589.1    
 BN4615_P3407   Nonomuraea gerenzanensis ATCC 39727 SBO93891.1    
 BN4615_P10725   Nonomuraea gerenzanensis ATCC 39727 SBP01209.1    
 BN4615_P9424   Nonomuraea gerenzanensis ATCC 39727 SBO99908.1    
 BN4615_P494   Nonomuraea gerenzanensis ATCC 39727 SBO90980.1    
 BN4615_P10280   Nonomuraea gerenzanensis ATCC 39727 SBP00764.1    
 LCN96_45090   Nonomuraea gerenzanensis L70 UBU11425.1    
 LCN96_51760   Nonomuraea gerenzanensis L70 UBU12653.1    
 LCN96_55380   Nonomuraea gerenzanensis L70 UBU13325.1    
 LCN96_49450   Nonomuraea gerenzanensis L70 UBU12233.1    
 LCN96_14075   Nonomuraea gerenzanensis L70 UBU16088.1    
 GBF35_40595   Nonomuraea nitratireducens WYY166 QFY12040.1    
 GBF35_50865   Nonomuraea nitratireducens WYY166 QFY13761.1    
 GBF35_46940   Nonomuraea nitratireducens WYY166 QFY13107.1    
 GBF35_46880   Nonomuraea nitratireducens WYY166 QFY13095.1    
 WBK31_13770   Nonomuraea sp. N2-4H WXK67505.1    
 WBK31_10845   Nonomuraea sp. N2-4H WXK66969.1    
 Oter_4325   Opitutus terrae PB90-1 ACB77597.1    
 MT999_06620   Ornithobacterium rhinotracheale 97 UOH64884.1     2
 MT999_09395   Ornithobacterium rhinotracheale 97 UOH65401.1     2
 MT999_09400   Ornithobacterium rhinotracheale 97 UOH65402.1     3
 MT993_05000   Ornithobacterium rhinotracheale A171 UOH64575.1     3
 MT993_07790   Ornithobacterium rhinotracheale A171 UOH62910.1     2
 MT993_05005   Ornithobacterium rhinotracheale A171 UOH64576.1     2
 Ornrh_0807   Ornithobacterium rhinotracheale DSM 15997 AFL97003.1     2
 Ornrh_0305   Ornithobacterium rhinotracheale DSM 15997 AFL96523.1     2
 Ornrh_0808   Ornithobacterium rhinotracheale DSM 15997 AFL97004.1     3
 EQP59_06600   Ornithobacterium rhinotracheale FARPER-174b QAR31025.1     2
 NV236_04380   Ornithobacterium rhinotracheale IRI-Sh UVD88098.1     3
 NV236_01570   Ornithobacterium rhinotracheale IRI-Sh UVD87573.1     2
 NV236_04375   Ornithobacterium rhinotracheale IRI-Sh UVD88097.1     2
 MT996_05980   Ornithobacterium rhinotracheale K223 UOH76777.1     2
 MT996_01510   Ornithobacterium rhinotracheale K223 UOH78161.1     2
 MT996_01505   Ornithobacterium rhinotracheale K223 UOH78160.1     3
 Q785_04595   Ornithobacterium rhinotracheale ORT-UMN 88 AIP99140.1     2
 Q785_01660   Ornithobacterium rhinotracheale ORT-UMN 88 AIQ00290.1     2
 Q785_04600   Ornithobacterium rhinotracheale ORT-UMN 88 AIP99141.1     3
 chondroitin AC lyase (partial) 4.2.2.1
4.2.2.5		 Paenarthrobacter aurescens   P84141 1RWA[A]
1RWC[A]
1RWF[A]
1RWG[A]
1RWH[A]
1RW9[A]
 AAur_3068   Paenarthrobacter aurescens TC1 ABM09726.1    
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