Activities in Family	Exo-β-1,4-glucuronan lyase (EC 4.2.2.-); Exo-hyaluronate lyase (EC 4.2.2.-); Hyaluronate lyase (EC 4.2.2.1); Xanthan lyase (EC 4.2.2.12); Chondroitinase B (EC 4.2.2.19); Poly(β-mannuronate) lyase / M-specific alginate lyase (EC 4.2.2.3); Chondroitin AC lyase (EC 4.2.2.5); Heparin lyase / heparin lyase I (EC 4.2.2.7);
Mechanism	b-elimination
3D Structure Status	( α / α ) 6 toroid + anti-parallel β-sheet
Commercial Enzyme Provider(s)	MEGAZYME; PROZOMIX;
Statistics	GenBank accession (4733); Uniprot accession (30); PDB accession (54); 3D entries (13); cryst (1)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
G8766_02905		Lactococcus garvieae Bacchus	UKS68184.1
LG21E68_13630		Lactococcus garvieae L21-68	BDW51688.1
J0J32_06820		Lactococcus garvieae LG728	QSQ97791.1
LGMS210922A_13650		Lactococcus garvieae MS210922A	BDM76420.1
LLID5_10250		Lactococcus lactis ID-5	BDH83740.1
BFR49_10895 (fragment)		Lactococcus lactis subsp. lactis WFLU12	ASX25169.1
BFR49_10900 (fragment)		Lactococcus lactis subsp. lactis WFLU12	ASX25170.1
lgb_01413		Lactococcus petauri B1726	UQU60648.1
QR692_08015		Lactococcus petauri GB97	WJE12111.1
LMK05_09080		Lactococcus petauri LG26	USI64984.1
LMK04_08020		Lactococcus petauri LG4	USI67429.1
J0J33_09670		Lactococcus sp. LG1267	QSR03993.1
JZX84_07750		Lactococcus sp. LG592	QSR10303.1
NCTC4824_01130		Lederbergia lenta NCTC4824	SQI53825.1
NCTC4824_01128		Lederbergia lenta NCTC4824	SQI53822.1
NCTC4824_03984		Lederbergia lenta NCTC4824	SQI63227.1
SAMN04515683_3564		Leifsonia sp. 157MF	SDK47213.1
SAMN04515690_0582		Leifsonia sp. 197AMF	SDH07438.1
SAMN04515680_3029		Leifsonia sp. 21MFCrub1.1	SEB07332.1
SAMN04515684_3201		Leifsonia sp. 466MF	SDJ32702.1
SAMN04515685_3546		Leifsonia sp. 467MF	SEN56312.1
SAMN04515686_1386		Leifsonia sp. 509MF	SDN53793.1
SAMN04515691_3435		Leifsonia sp. 98AMF	SFM73036.1
HF024_19050		Leifsonia sp. PS1209	QJA00392.1
IT072_18960		Leifsonia sp. ZF2019	UAJ79255.1
PQO03_08425		Lentisphaera profundi SAORIC-696	WDE95739.1			2
PQO03_18540		Lentisphaera profundi SAORIC-696	WDE97827.1
PQO03_05560		Lentisphaera profundi SAORIC-696	WDE97416.1			2
LJT99_09360		Lentisphaerae bacterium WC36	UDQ96701.1
LJT99_14470		Lentisphaerae bacterium WC36	UDQ97647.1
LJT99_07475		Lentisphaerae bacterium WC36	UDQ99370.1
SMSP2_01425 (Chonabc_2)		Limihaloglobus sulfuriphilus SM-Chi-D1	AQQ71061.1			2
SMSP2_01417 (Chonabc_1)		Limihaloglobus sulfuriphilus SM-Chi-D1	AQQ71053.1			2
OTR81_05830		Listeria newyorkensis CMB191063	WAO22789.1
OTR81_07225		Listeria newyorkensis CMB191063	WAO23051.1
UE46_15580		Listeria weihenstephanensis WS 4560	AQY52297.1
UE46_14495		Listeria weihenstephanensis WS 4560	AQY52590.1
KDY119_02305 (HysA)		Luteimicrobium xylanilyticum HY-24	QFU98786.1
VV02_06880		Luteipulveratus mongoliensis MN07-A0370	AKU15639.1
KBB96_12730		Luteolibacter ambystomatis 32A	QUE49735.1
KBB96_20245 (fragment)		Luteolibacter ambystomatis 32A	QUE51172.1
llg_20350		Luteolibacter sp. LG18	BCU77320.1
llg_21840		Luteolibacter sp. LG18	BCU77469.1
GM418_02630		Maribellus comscasis WC007	QGY42584.1
GM418_02650		Maribellus comscasis WC007	QGY42588.1
DGI_2110		Megalodesulfovibrio gigas DSM 1382 = ATCC 19364	AGW13874.1
NCTC10147_01234 (HylB)		Mesomycoplasma conjunctivae NCTC10147	VEU67094.1
K8L98_24575		Metabacillus dongyingensis BY2G20	UAL52281.1
QLQ22_24795		Metabacillus sp. CT-WN-B3	WHZ57817.1
QUC20_10665		Microbacterium arborescens SSF12	WJM14740.1
NFX31_16015		Microbacterium azadirachtae CNUC13	UXW85688.1
LXM64_13715		Microbacterium binotii Au-Mic3	UIN30185.1
HCR76_14735		Microbacterium chengjingii HY60	QPZ38034.1			2
FVO59_03415		Microbacterium esteraromaticum B24	QMU96360.1
FVO59_04000		Microbacterium esteraromaticum B24	QMU96463.1
FVO59_06070		Microbacterium esteraromaticum B24	QMU96836.1
PTQ19_12450		Microbacterium esteraromaticum DEHP-1	WDH78317.1
PTQ19_00485		Microbacterium esteraromaticum DEHP-1	WDH78953.1
HW566_14110		Microbacterium oleivorans I46	QLD12808.1
P6897_11035		Microbacterium sp. BDGP8	WHE35229.1
LQ938_01530		Microbacterium sp. cx-55	UGB35505.1
MNR00_16720		Microbacterium sp. H1-D42	UNK70775.1
MNR00_02150		Microbacterium sp. H1-D42	UNK71278.1			2
glycosaminoglycan lyase		Microbacterium sp. H14	QGL52623.1
L2X99_17195		Microbacterium sp. KUDC0406	UJP10061.1
L2X99_09660		Microbacterium sp. KUDC0406	UJP08781.1
PGB26_09015		Microbacterium sp. nov. GSS16	WCD91821.1			2
KV396_07850		Microbacterium sp. SSW1-36	UPL14390.1
xanthan lyase (AB663_001102)	4.2.2.12	Microbacterium sp. XT11	ALX66168.1
MTES_2849		Microbacterium testaceum StLB037	BAJ75813.1
FOE78_16715		Microlunatus elymi KUDC0627	QDP97345.1
SAMN04489812_4258		Microlunatus soli DSM 21800	SDT13119.1
QU516_11140		Moellerella wisconsensis NX2019MW	WJW81194.1			2
QU516_11145		Moellerella wisconsensis NX2019MW	WJW81195.1			2
QU516_01525		Moellerella wisconsensis NX2019MW	WJW82169.1
MNY70_11930		Moellerella wisconsensis W1	UNH38186.1			2
MNY70_11925		Moellerella wisconsensis W1	UNH38185.1			2
MNY70_01545		Moellerella wisconsensis W1	UNH39195.1
MNY68_11620		Moellerella wisconsensis W17-3	UNH23464.1			2
MNY68_11625		Moellerella wisconsensis W17-3	UNH23465.1			2
MNY68_01520		Moellerella wisconsensis W17-3	UNH24471.1
MNY64_11855		Moellerella wisconsensis W18-2	UNH26544.1			2
MNY64_01620		Moellerella wisconsensis W18-2	UNH27575.1
MNY64_11860		Moellerella wisconsensis W18-2	UNH26545.1			2
MNY72_11430		Moellerella wisconsensis W51	UNH29961.1			2
MNY72_11425		Moellerella wisconsensis W51	UNH29960.1			2
MNY72_01595		Moellerella wisconsensis W51	UNH31049.1
MNY66_01525		Moellerella wisconsensis W65	UNH42717.1
MNY66_11580		Moellerella wisconsensis W65	UNH41681.1			2
MNY66_11575		Moellerella wisconsensis W65	UNH41680.1			2
HQ865_05340		Mucilaginibacter mali G2-14	QKJ29199.1
HQ865_11825		Mucilaginibacter mali G2-14	QKJ30415.1
HQ865_05360		Mucilaginibacter mali G2-14	QKJ29203.1
MCRO_0392		Mycoplasma crocodyli MP145	ADE19838.1
MFE_04780		Mycoplasmopsis fermentans JER	ADN69073.1
MfeM64YM_0614		Mycoplasmopsis fermentans M64	ADV34612.1
NCTC10117_01915		Mycoplasmopsis fermentans NCTC10117	VEU63916.1
MBIO_0039		Mycoplasmopsis fermentans PG18	BAH69304.1
NCTC10183_00193		Mycoplasmopsis gallinacea NCTC10183	VEU58436.1
GOQ20_04330		Mycoplasmopsis gallinacea Peacock20181011	QIW62608.1
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