GlycosylTransferase Family 8

Activities in Familylipopolysaccharide α-1,3-galactosyltransferase (EC 2.4.1.44); UDP-Glc: (glucosyl)lipopolysaccharide α-1,2-glucosyltransferase (EC 2.4.1.-); lipopolysaccharide glucosyltransferase 1 (EC 2.4.1.58); glycogenin glucosyltransferase (EC 2.4.1.186); inositol 1-α-galactosyltransferase (galactinol synthase) (EC 2.4.1.123); homogalacturonan α-1,4-galacturonosyltransferase (EC 2.4.1.43); UDP-GlcA: xylan α-glucuronyltransferase (EC 2.4.1.-); UDP-Gal:glucoside α-1,3-galactosyltransferase (EC 2.4.1.-)
Mechanism Retaining
3D Structure StatusGT-A
NoteDistant similarity to family GT24; The animal LARGE bifunctional glycosyltransferases are made of two domains. The N-terminal domain, which adds a-1,3-Xyl residues, belongs to family GT8 while the C-terminal domain, which adds b-1,3-GlcA residues, belongs to family GT49.
External resourcesGlymap; HOMSTRAD;
Commercial Enzyme Provider(s)CHEMILY;
Statistics GenBank accession (13759); Uniprot accession (1210); PDB accession (45); 3D entries (10); cryst (0)
All (12162) Archaea (9) Bacteria (10293) Eukaryota (1683) Viruses (174) unclassified (3) Structure (10) Characterized (53)
| 1 | 2 |
Viruses
Protein Name EC#OrganismGenBank UniprotPDB/3D
 p13 (fragment)   Leucania separata nucleopolyhedrovirus BAA19093.1    
 p13   Mamestra brassicae multiple nucleopolyhedrovirus AIL25146.1    
 Mb_orf68   Mamestra brassicae multiple nucleopolyhedrovirus CHb1 AFP95787.1    
 MabrNPVgp067 (P13)   Mamestra brassicae multiple nucleopolyhedrovirus K1 AFL64918.1    
 ORF 76   Mamestra configurata nucleopolyhedrovirus A AAQ11095.1
AAM09184.1
NP_613159.1
Q8QLF8  
 p13   Mamestra configurata nucleopolyhedrovirus A QEE79963.1    
 p13-like protein (P13)   Mamestra configurata nucleopolyhedrovirus B AAM95062.1
NP_689250.1
Q8JM77  
 LCMAC103_03460   Marseillevirus LCMAC103 QBK87002.1    
 Mg258   Megavirus chiliensis AEQ32783.1    
 CE11_00263 (fragment)   Megavirus courdo11 AFX92293.1    
 CE11_00264 (fragment)   Megavirus courdo11 AFX92294.1    
 c7_R283 (fragment)   Megavirus courdo7 AEX61349.1    
 c7_R284 (fragment)   Megavirus courdo7 AEX61350.1    
 LBA_00245   Megavirus lba AGD92165.1    
 mvi_241   Megavirus vitis AVL93601.1    
 ORF   Mimivirus Bombay AMZ03151.1    
 LCMiAC02_01770   Mimivirus LCMiAC02 QBK89084.1    
 ORF   Mimivirus sp. SH AZL89968.1    
 P13   Mocis sp. granulovirus AKR17416.1    
 glt_00760   Moumouvirus goulette AGF85565.1    
 mv_L897 (fragment)   Moumouvirus Monve AEX63099.1    
 mv_L896 (fragment)   Moumouvirus Monve AEX63098.1    
 P13   Mythimna unipuncta granulovirus AQQ80309.1    
 P13   Mythimna unipuncta nucleopolyhedrovirus #7 AUV65332.1    
 P13   Mythimna unipuncta nucleopolyhedrovirus KY310 AXU41550.1    
 ORF   Niemeyer virus ALR84330.1    
 ORF   Niemeyer virus ALR84416.1    
 P13   Operophtera brumata nucleopolyhedrovirus AUA60324.1    
 P13   Ophiusa disjungens nucleopolyhedrovirus OdMNPV-SCAU ACI43906.1 B6E2B6  
 PACV_108   Pacmanvirus A23 SIP85824.1    
 pesp091   Peridroma alphabaculovirus AIE47818.1    
 P13   Perigonia lusca single nucleopolyhedrovirus AKN80665.1    
 PhopGV042   Phthorimaea operculella granulovirus AAM70240.1
ANY57431.1
NP_663207.1
QBH65877.1
QBH66007.1
QBH66137.1
QBH66267.1
QBH66397.1
QBH66527.1
QBH66657.1
QBH66787.1
QBH66917.1
QBH67046.1
QBH67176.1
Q8JS17  
 PhopGVgp042 (P13)   Phthorimaea operculella granulovirus QBH67306.1    
 PrGVORF38 / Pirα-GV_ORF038 (P13)   Pieris rapae granulovirus ACZ63524.1
ADO85464.1
AGS18801.1
D2J4K5  
 LCPAC001_02030   Pithovirus LCPAC001 QBK89690.1    
 LCPAC403_02980   Pithovirus LCPAC403 QBK93164.1    
 LCPAC404_01100   Pithovirus LCPAC404 QBK93406.1    
 P13   Plodia interpunctella granulovirus APO13923.1    
 PxGV-Morf36 protein   Plutella xylostella granulovirus AMQ35882.1    
 PxGV-Torf36 protein   Plutella xylostella granulovirus AMQ35999.1    
 PxGV-Korf36 protein   Plutella xylostella granulovirus AMQ35765.1    
 PxGV-Corf36 protein   Plutella xylostella granulovirus AMQ35648.1    
 PlxyGVORF36 protein (Plxygv036)   Plutella xylostella granulovirus ANY57555.1    
 ORF36   Plutella xylostella granulovirus K1 AAG27334.1
NP_068255.1
Q9DVZ6  
 ORF   Powai lake megavirus ANB50379.1    
 P13 (Orf41)   Pseudalatia unipuncta granulovirus Hawaiin ACH69391.1 B6S6R0  
 P13 (Orf-99)   Pseudoplusia includens SNPV IE AJD80789.1    
 ORF (fragment)   Samba virus AHJ40331.2    
 R730   Samba virus AHJ40331.1    
 ORF   Saudi moumouvirus AQN68077.1    
 P13   Spodoptera eridania nucleopolyhedrovirus AXU41657.1    
 P13   Spodoptera exempta nucleopolyhedrovirus 244.1 QAT90339.1    
 SENV_ORF47 (P13)   Spodoptera exigua multiple nucleopolyhedrovirus AYN45007.1    
 ORF56   Spodoptera exigua multiple nucleopolyhedrovirus AAF33586.1
NP_037816.1
Q9J879  
 HTSEG24_054   Spodoptera exigua multiple nucleopolyhedrovirus CDG72808.1
CDG72397.1
CDG72960.1
CDG73097.1
CDG73235.1
   
 VTSEOX4_054   Spodoptera exigua multiple nucleopolyhedrovirus CDG72671.1
CDG72534.1
   
 p13   Spodoptera frugiperda granulovirus AXS01055.1    
 p13   Spodoptera frugiperda granulovirus AJK91697.1    
 P13 protein   Spodoptera frugiperda multiple nucleopolyhedrovirus AIW01467.1    
 Sf56   Spodoptera frugiperda multiple nucleopolyhedrovirus ADV91288.1
AFH59007.1
   
 p13   Spodoptera frugiperda multiple nucleopolyhedrovirus 3AP2 ABM45766.1 A1YJ46  
 P13 protein   Spodoptera littoralis nucleopolyhedrovirus AYU75283.1    
 SlsnVgp094   Spodoptera littoralis nucleopolyhedrovirus AGE89949.1    
 SlGVgp038   Spodoptera litura granulovirus ABQ51981.1 A5IZP0  
 P13 protein   Spodoptera litura nucleopolyhedrovirus G2 AAL01781.1
AAG31691.1
NP_258367.1
Q9E7P3  
 P13 (Orf60)   Spodoptera litura nucleopolyhedrovirus II ACI47429.1 B7SVT7  
 Terrestrivirus2_224   Terrestrivirus sp. AYV75716.1    
 TetV_644   Tetraselmis virus 1 AUF82726.1    
 p13   Trichoplusia ni granulovirus AOW41374.1    
 p13   Trichoplusia ni single nucleopolyhedrovirus QBI90321.1    
 orf97   Trichoplusia ni single nucleopolyhedrovirus AAZ67467.1 Q461W9  
 glycosyltransferase   Tupanvirus deep ocean AUL80027.1    
 XecnGVgp043 (Orf43)   Xestia c-nigrum granulovirus AAF05157.1
NP_059191.1
Q9PZ00  
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