Glycoside Hydrolase Family 97

Activities in Familyα-glucosidase (EC 3.2.1.20);
α-galactosidase (EC 3.2.1.22);
[inverting] glucoamylase (EC 3.2.1.3);
[retaining] β-L-arabinopyranosidase / β-L-arabinosidase (EC 3.2.1.88);
Mechanism Inverting and retaining a
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu for inverting members; Asp for retaining members
Catalytic Proton DonorGlu
NoteCreated based on a paper by Hughes et al. (2003) Oral Microbiol Immunol. 18:309-312 (PMID: 12930523); *Mechanistic and structural elucidation by Gloster et al. (2008) Chem. Biol., Oct 8 (PMID:18848471); the inverting a-glucosidases (EC 3.2.1.20) could be renamed glucoamylases (EC 3.2.1.3 according to Kitamura et al. (2008) J. Biol. Chem., Nov 3 (PMID:18981178)
External resourcesCAZypedia;
Statistics GenBank accession (5703); Uniprot accession (11); PDB accession (13); 3D entries (4); cryst (0)
| 1 | ... | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | ... | 56 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 KQP69_07920   Bacteroides thetaiotaomicron VPI-2808B UYV02177.1    
 KQP69_14500   Bacteroides thetaiotaomicron VPI-2808B UYU98839.1    
 KQP69_01400   Bacteroides thetaiotaomicron VPI-2808B UYV00938.1    
 KQP69_21795   Bacteroides thetaiotaomicron VPI-2808B UYV00209.1    
 KQP69_05570   Bacteroides thetaiotaomicron VPI-2808B UYV01736.1    
 KQP69_14265   Bacteroides thetaiotaomicron VPI-2808B UYU98794.1    
 KQP69_07900   Bacteroides thetaiotaomicron VPI-2808B UYV02173.1    
 KQP69_21590   Bacteroides thetaiotaomicron VPI-2808B UYV00169.1    
 KQP69_15125   Bacteroides thetaiotaomicron VPI-2808B UYU98954.1    
 KQP56_05380   Bacteroides thetaiotaomicron VPI-3164 UYU96930.1    
 KQP56_16515   Bacteroides thetaiotaomicron VPI-3164 UYU94229.1    
 KQP56_11065   Bacteroides thetaiotaomicron VPI-3164 UYU97994.1    
 KQP56_12420   Bacteroides thetaiotaomicron VPI-3164 UYU98242.1    
 KQP56_23485   Bacteroides thetaiotaomicron VPI-3164 UYU95553.1    
 KQP56_06855   Bacteroides thetaiotaomicron VPI-3164 UYU97215.1    
 KQP56_15905   Bacteroides thetaiotaomicron VPI-3164 UYU94117.1    
 KQP56_06665   Bacteroides thetaiotaomicron VPI-3164 UYU97177.1    
 KQP56_06870   Bacteroides thetaiotaomicron VPI-3164 UYU97218.1    
 KQP74_14535   Bacteroides thetaiotaomicron VPI-3443 UYU89169.1    
 KQP74_04460   Bacteroides thetaiotaomicron VPI-3443 UYU91895.1    
 KQP74_12665   Bacteroides thetaiotaomicron VPI-3443 UYU88815.1    
 KQP74_22210   Bacteroides thetaiotaomicron VPI-3443 UYU90602.1    
 KQP74_06960   Bacteroides thetaiotaomicron VPI-3443 UYU92362.1    
 KQP74_14330   Bacteroides thetaiotaomicron VPI-3443 UYU89128.1    
 KQP74_01835   Bacteroides thetaiotaomicron VPI-3443 UYU91400.1    
 KQP74_21655   Bacteroides thetaiotaomicron VPI-3443 UYU90503.1    
 KQP74_14520   Bacteroides thetaiotaomicron VPI-3443 UYU89166.1    
 KQP74_05695   Bacteroides thetaiotaomicron VPI-3443 UYU92125.1    
 KQP74_02910   Bacteroides thetaiotaomicron VPI-3443 UYU91602.1    
 BT4581   Bacteroides thetaiotaomicron VPI-5482 AAO79686.1
NP_813492.1
   
 α-glucosidase (BT0683) 3.2.1.20 Bacteroides thetaiotaomicron VPI-5482 AAO75790.1
NP_809596.1
Q8A9Y2  
 BT0132   Bacteroides thetaiotaomicron VPI-5482 AAO75239.1
NP_809045.1
   
 α-galactosidase (BtGH97b; BT1871; BT_1871) 3.2.1.22 Bacteroides thetaiotaomicron VPI-5482 AAO76978.1
NP_810784.1
Q8A6L0 3A24[A,B]
5E1Q[A,B]
 α-galactosidase (BT3294; BT_3294) 3.2.1.22 Bacteroides thetaiotaomicron VPI-5482 AAO78400.1
NP_812206.1
Q8A2L1  
 α-mannan α-galactosidase (BT2620) 3.2.1.22 Bacteroides thetaiotaomicron VPI-5482 AAO77727.1
NP_811533.1
Q8A4H9  
 BT3163   Bacteroides thetaiotaomicron VPI-5482 AAO78269.1
NP_812075.1
   
 α-galactosidase (BT3664) 3.2.1.22 Bacteroides thetaiotaomicron VPI-5482 AAO78769.1
NP_812575.1
Q8A1J7  
 bifunctional β-L-arabinopyranosidase/α-D-galactosidase (BT3661) 3.2.1.22
3.2.1.88
Bacteroides thetaiotaomicron VPI-5482 AAO78766.1
NP_812572.1
Q8A1K0 5XFM[A,B,C,D]
 α-glucosidase / glucoamylase (SusB; BtGH97a; BT3703; BT_3703) 3.2.1.3 Bacteroides thetaiotaomicron VPI-5482 AAO78808.1
AAC44671.1
NP_812614.1
G8JZS4
P71094
2D73[A,B]
2JKA[A,B]
2JKE[A,B]
2JKP[A,B]
2ZQ0[A,B]
3WFA[A,B]
 KP721_17120   Bacteroides thetaiotaomicron VPI-5482A UYU84913.1    
 KP721_15675   Bacteroides thetaiotaomicron VPI-5482A UYU84639.1    
 KP721_18120   Bacteroides thetaiotaomicron VPI-5482A UYU85096.1    
 KP721_05830   Bacteroides thetaiotaomicron VPI-5482A UYU87304.1    
 KP721_00475   Bacteroides thetaiotaomicron VPI-5482A UYU86304.1    
 KP721_05850   Bacteroides thetaiotaomicron VPI-5482A UYU87307.1    
 KP721_14415   Bacteroides thetaiotaomicron VPI-5482A UYU84401.1    
 KP721_13480   Bacteroides thetaiotaomicron VPI-5482A UYU84221.1    
 KP721_05645   Bacteroides thetaiotaomicron VPI-5482A UYU87267.1    
 KP721_08470   Bacteroides thetaiotaomicron VPI-5482A UYU87806.1    
 KQP77_06105   Bacteroides thetaiotaomicron VPI-BT7853 UYU82712.1    
 KQP77_18275   Bacteroides thetaiotaomicron VPI-BT7853 UYU80410.1    
 KQP77_13705   Bacteroides thetaiotaomicron VPI-BT7853 UYU79544.1    
 KQP77_15040   Bacteroides thetaiotaomicron VPI-BT7853 UYU79799.1    
 KQP77_03745   Bacteroides thetaiotaomicron VPI-BT7853 UYU82269.1    
 KQP77_06085   Bacteroides thetaiotaomicron VPI-BT7853 UYU82708.1    
 KQP77_04840   Bacteroides thetaiotaomicron VPI-BT7853 UYU82476.1    
 KQP77_15665   Bacteroides thetaiotaomicron VPI-BT7853 UYU79915.1    
 KQP77_19905   Bacteroides thetaiotaomicron VPI-BT7853 UYU80718.1    
 KQP77_03725   Bacteroides thetaiotaomicron VPI-BT7853 UYU82266.1    
 KQP77_03540   Bacteroides thetaiotaomicron VPI-BT7853 UYU82229.1    
 KQP72_24540   Bacteroides thetaiotaomicron VPI-BT8702 UYU76190.1    
 KQP72_06455   Bacteroides thetaiotaomicron VPI-BT8702 UYU77701.1    
 KQP72_10045   Bacteroides thetaiotaomicron VPI-BT8702 UYU78381.1    
 KQP72_06575   Bacteroides thetaiotaomicron VPI-BT8702 UYU77724.1    
 KQP72_20620   Bacteroides thetaiotaomicron VPI-BT8702 UYU75447.1    
 KQP72_21930   Bacteroides thetaiotaomicron VPI-BT8702 UYU75694.1    
 KQP72_22140   Bacteroides thetaiotaomicron VPI-BT8702 UYU75736.1    
 KQP72_21945   Bacteroides thetaiotaomicron VPI-BT8702 UYU75697.1    
 KQP72_25200   Bacteroides thetaiotaomicron VPI-BT8702 UYU76312.1    
 KQP72_23025   Bacteroides thetaiotaomicron VPI-BT8702 UYU75907.1    
 KQP59_16995   Bacteroides thetaiotaomicron VPI-BTDOT2 UYU69968.1    
 KQP59_17180   Bacteroides thetaiotaomicron VPI-BTDOT2 UYU70005.1    
 KQP59_18830   Bacteroides thetaiotaomicron VPI-BTDOT2 UYU70314.1    
 KQP59_15455   Bacteroides thetaiotaomicron VPI-BTDOT2 UYU69682.1    
 KQP59_19510   Bacteroides thetaiotaomicron VPI-BTDOT2 UYU70444.1    
 KQP59_16230   Bacteroides thetaiotaomicron VPI-BTDOT2 UYU69823.1    
 KQP59_23385   Bacteroides thetaiotaomicron VPI-BTDOT2 UYU71169.1    
 KQP59_17150   Bacteroides thetaiotaomicron VPI-BTDOT2 UYU69999.1    
 KQP59_21995   Bacteroides thetaiotaomicron VPI-BTDOT2 UYU70916.1    
 KQP59_01500   Bacteroides thetaiotaomicron VPI-BTDOT2 UYU71816.1    
 KQP59_11680   Bacteroides thetaiotaomicron VPI-BTDOT2 UYU73729.1    
 KQP59_12400   Bacteroides thetaiotaomicron VPI-BTDOT2 UYU73859.1    
 KQP59_14155   Bacteroides thetaiotaomicron VPI-BTDOT2 UYU74082.1    
 KQP68_05250   Bacteroides thetaiotaomicron WAL8669 UYU67691.1    
 KQP68_13375   Bacteroides thetaiotaomicron WAL8669 UYU64577.1    
 KQP68_04865   Bacteroides thetaiotaomicron WAL8669 UYU67617.1    
 KQP68_13260   Bacteroides thetaiotaomicron WAL8669 UYU64559.1    
 KQP68_11715   Bacteroides thetaiotaomicron WAL8669 UYU68883.1    
 KQP68_05055   Bacteroides thetaiotaomicron WAL8669 UYU67652.1    
 KQP68_21120   Bacteroides thetaiotaomicron WAL8669 UYU66043.1    
 KQP68_19125   Bacteroides thetaiotaomicron WAL8669 UYU65671.1    
 KQP68_19795   Bacteroides thetaiotaomicron WAL8669 UYU65792.1    
 KQP68_05265   Bacteroides thetaiotaomicron WAL8669 UYU67694.1    
 KQP65_15555   Bacteroides thetaiotaomicron WAL8713 UYU59856.1    
 KQP65_14920   Bacteroides thetaiotaomicron WAL8713 UYU59744.1    
 KQP65_24725   Bacteroides thetaiotaomicron WAL8713 UYU61582.1    
 KQP65_15715   Bacteroides thetaiotaomicron WAL8713 UYU59887.1    
 KQP65_12990   Bacteroides thetaiotaomicron WAL8713 UYU64237.1    
 KQP65_00625   Bacteroides thetaiotaomicron WAL8713 UYU61919.1    
 KQP65_18890   Bacteroides thetaiotaomicron WAL8713 UYU60485.1    
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