Glycoside Hydrolase Family 97

Activities in Familyα-glucosidase (EC 3.2.1.20);
α-galactosidase (EC 3.2.1.22);
[inverting] glucoamylase (EC 3.2.1.3);
Glucodextranase (EC 3.2.1.70);
[retaining] β-L-arabinopyranosidase / β-L-arabinosidase (EC 3.2.1.88);
Mechanism Inverting and retaining a
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu for inverting members; Asp for retaining members
Catalytic Proton DonorGlu
NoteCreated based on a paper by Hughes et al. (2003) Oral Microbiol Immunol. 18:309-312 (PMID: 12930523); *Mechanistic and structural elucidation by Gloster et al. (2008) Chem. Biol., Oct 8 (PMID:18848471); the inverting a-glucosidases (EC 3.2.1.20) could be renamed glucoamylases (EC 3.2.1.3 according to Kitamura et al. (2008) J. Biol. Chem., Nov 3 (PMID:18981178)
External resourcesCAZypedia;
Statistics GenBank accession (5778); Uniprot accession (13); PDB accession (16); 3D entries (5); cryst (0)
Bacteria
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 α-glucosidase (BT0683) 3.2.1.20 pubmed
Bacteroides thetaiotaomicron VPI-5482 AAO75790.1
NP_809596.1
Q8A9Y2  
 α-galactosidase (BtGH97b; BT1871; BT_1871) 3.2.1.22 pubmed
Bacteroides thetaiotaomicron VPI-5482 AAO76978.1
NP_810784.1
Q8A6L0 3A24[A,B]
5E1Q[A,B]
 α-galactosidase (BT3294; BT_3294) 3.2.1.22 pubmed
Bacteroides thetaiotaomicron VPI-5482 AAO78400.1
NP_812206.1
Q8A2L1  
 α-mannan α-galactosidase (BT2620) 3.2.1.22 pubmed
Bacteroides thetaiotaomicron VPI-5482 AAO77727.1
NP_811533.1
Q8A4H9  
 α-galactosidase (BT3664) 3.2.1.22 pubmed
Bacteroides thetaiotaomicron VPI-5482 AAO78769.1
NP_812575.1
Q8A1J7  
 bifunctional β-L-arabinopyranosidase/α-D-galactosidase (BT3661) 3.2.1.22
3.2.1.88
pubmed
pubmed
Bacteroides thetaiotaomicron VPI-5482 AAO78766.1
NP_812572.1
Q8A1K0 5XFM[A,B,C,D]
 α-glucosidase / glucoamylase (SusB; BtGH97a; BT3703; BT_3703) 3.2.1.3 pubmed
Bacteroides thetaiotaomicron VPI-5482 AAO78808.1
AAC44671.1
NP_812614.1
G8JZS4
P71094
2D73[A,B]
2JKA[A,B]
2JKE[A,B]
2JKP[A,B]
2ZQ0[A,B]
3WFA[A,B]
 dextran exo-α-1,6-glucosidase (FjGH97A; Fjoh_4429) 3.2.1.70 pubmed
Flavobacterium johnsoniae UW101 ABQ07433.1 A5FBI0 8WG0[A,B,C,D]
8WG1[A,B,C,D]
8WG2[A,B,C,D]
 dextran exo-α-1,6-glucosidase (PspAG97A) (Ag97A) 3.2.1.70 pubmed
Pseudoalteromonas sp. K8 AMB20699.1 A0A0Y0DFX2 5HQ4[A]
5HQA[A]
5HQB[A]
5HQC[A]
 α-glucosidase (SusB;Aglu;BFO_2272) 3.2.1.20 pubmed
Tannerella forsythia 92A2 AEW20125.1
AAO33827.1
G8UJE0
Q84FT4
 
 retaining α-galactosidase (CapGH97) 3.2.1.22 pubmed
uncultured Bacteroidaceae bacterium UMW87591.1    
unclassified
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 α-galactosidase (Agas2) 3.2.1.22 pubmed
insect gut metagenome ARK08558.1 A0A1W6DZM5  
Top


Last update: 2024-05-29 © Copyright 1998-2024
AFMB - CNRS - Université d'Aix-Marseille