| Known Activities | α-glucosidase (EC 3.2.1.20); α-galactosidase (EC 3.2.1.22) |
|---|---|
| Mechanism | inverting and retain |
| 3D Structure Status | ( β / α ) 8 |
| Catalytic Nucleophile/Base | Glu for inverting members; Asp for retaining members |
| Catalytic Proton Donor | Glu |
| Note | Created based on a paper by Hughes et al. (2003) Oral Microbiol Immunol. 18:309-312 (PMID: 12930523); *Mechanistic and structural elucidation by Gloster et al. (2008) Chem. Biol., Oct 8 (PMID:18848471); the inverting a-glucosidases (EC 3.2.1.20) could be renamed glucoamylases (EC 3.2.1.3 according to Kitamura et al. (2008) J. Biol. Chem., Nov 3 (PMID:18981178) |
| External resources | CAZypedia; |
| Statistics | GenBank accession (132); Uniprot accession (63); PDB accession (6); 3D entries (2); cryst (0) |
| Bacteria | ||||||
| Protein Name | EC# | Organism | GenBank | Uniprot | PDB/3D | |
| α-glucosidase (SusB;BtGH97a;BT3703;BT_3703) | 3.2.1.20 | Bacteroides thetaiotaomicron VPI-5482 | AAC44671.1 AAO78808.1 NP_812614.1 |
P71094 | 2D73[A,B] 2JKA[A,B] 2JKE[A,B] 2JKP[A,B] 2ZQ0[A,B] |
|
| α-galactosidase (BtGH97b;BT1871;BT_1871) | 3.2.1.22 | Bacteroides thetaiotaomicron VPI-5482 | AAO76978.1 NP_810784.1 |
3A24[A,B] | ||
| α-glucosidase (SusB) | 3.2.1.20 | Tannerella forsythia ATCC 43037 | AAO33827.1 | Q84FT4 | ||
Experimental characterization exclusively covers enzyme activities at present. If you are aware of any missing experimental characterization that should be mentioned here, we encourage you to send your comment and support of the experimental evidence, including an electronic copy or appropriate link to the support material (i.e., article(s), thesis, database, etc), to cazy@afmb.univ-mrs.fr.