Glycoside Hydrolase Family 97

Activities in Familyα-glucosidase (EC;
α-galactosidase (EC;
[inverting] glucoamylase (EC;
[retaining] β-L-arabinopyranosidase / β-L-arabinosidase (EC;
Mechanism Inverting and retaining a
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu for inverting members; Asp for retaining members
Catalytic Proton DonorGlu
NoteCreated based on a paper by Hughes et al. (2003) Oral Microbiol Immunol. 18:309-312 (PMID: 12930523); *Mechanistic and structural elucidation by Gloster et al. (2008) Chem. Biol., Oct 8 (PMID:18848471); the inverting a-glucosidases (EC could be renamed glucoamylases (EC according to Kitamura et al. (2008) J. Biol. Chem., Nov 3 (PMID:18981178)
External resourcesCAZypedia;
Statistics GenBank accession (5639); Uniprot accession (11); PDB accession (13); 3D entries (4); cryst (0)

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