Glycoside Hydrolase Family 97

Known Activitiesα-glucosidase (EC 3.2.1.20); α-galactosidase (EC 3.2.1.22)
Mechanism inverting and retain
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu for inverting members; Asp for retaining members
Catalytic Proton DonorGlu
NoteCreated based on a paper by Hughes et al. (2003) Oral Microbiol Immunol. 18:309-312 (PMID: 12930523); *Mechanistic and structural elucidation by Gloster et al. (2008) Chem. Biol., Oct 8 (PMID:18848471); the inverting a-glucosidases (EC 3.2.1.20) could be renamed glucoamylases (EC 3.2.1.3 according to Kitamura et al. (2008) J. Biol. Chem., Nov 3 (PMID:18981178)
External resourcesCAZypedia;
Statistics GenBank accession (251); Uniprot accession (146); PDB accession (6); 3D entries (2); cryst (0)
Bacteria
Protein Name EC#OrganismGenBankUniprotPDB/3D
 α-galactosidase (BtGH97b;BT1871;BT_1871) 3.2.1.22 Bacteroides thetaiotaomicron VPI-5482 AAO76978.1
NP_810784.1
  3A24[A,B]
 α-glucosidase (SusB;BtGH97a;BT3703;BT_3703) 3.2.1.20 Bacteroides thetaiotaomicron VPI-5482 AAC44671.1
AAO78808.1
NP_812614.1
P71094 2D73[A,B]
2JKA[A,B]
2JKE[A,B]
2JKP[A,B]
2ZQ0[A,B]




Last update: 2012-01-31 © Copyright 1998-2012
AFMB - CNRS - Universités Aix-Marseille I & II