Glycoside Hydrolase Family 97

Activities in Familyglucoamylase (EC 3.2.1.3); α-glucosidase (EC 3.2.1.20); α-galactosidase (EC 3.2.1.22)
Mechanism inverting and retain
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu for inverting members; Asp for retaining members
Catalytic Proton DonorGlu
NoteCreated based on a paper by Hughes et al. (2003) Oral Microbiol Immunol. 18:309-312 (PMID: 12930523); *Mechanistic and structural elucidation by Gloster et al. (2008) Chem. Biol., Oct 8 (PMID:18848471); the inverting a-glucosidases (EC 3.2.1.20) could be renamed glucoamylases (EC 3.2.1.3 according to Kitamura et al. (2008) J. Biol. Chem., Nov 3 (PMID:18981178)
External resourcesCAZypedia;
Statistics GenBank accession (1008); Uniprot accession (166); PDB accession (12); 3D entries (3); cryst (0)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 TL08_06870   Actinoalloteichus hymeniacidonis HPA177(T) (=DSM 45092(T)) AOS62196.1    
 AFR_28485   Actinoplanes friuliensis DSM 7358 AGZ43958.1    
 AFR_31770   Actinoplanes friuliensis DSM 7358 AGZ44614.1    
 L083_6201   Actinoplanes sp. N902-109 AGL19711.1    
 Amuc_1420   Akkermansia muciniphila ATCC BAA-835 ACD05243.1 B2UKX0  
 A4V05_02610   Akkermansia muciniphila YL44 ANU60415.1
ASB36057.1
   
 APS56_09820   Algibacter alginicilyticus HZ22 ALJ05397.1    
 APS56_06105   Algibacter alginicilyticus HZ22 ALJ04726.1    
 AO498_15685   Algoriphagus sp. M8-2 AMQ57895.1    
 AO498_05945   Algoriphagus sp. M8-2 AMQ55946.1    
 Alfi_1079   Alistipes finegoldii DSM 17242 AFL77433.1    
 Alfi_1931   Alistipes finegoldii DSM 17242 AFL78247.1    
 Alfi_0419   Alistipes finegoldii DSM 17242 AFL76815.1    
 Alfi_1673   Alistipes finegoldii DSM 17242 AFL78004.1    
 Alfi_2463   Alistipes finegoldii DSM 17242 AFL78734.1    
 Alfi_2092 (probable fragment)   Alistipes finegoldii DSM 17242 AFL78392.1    
 AL1_00490   Alistipes shahii WAL 8301 CBK62784.1 D4IIM6  
 AL1_13810   Alistipes shahii WAL 8301 CBK63835.1 D4ILM3  
 AL1_16660   Alistipes shahii WAL 8301 CBK64059.1 D4IM97  
 AL1_27120   Alistipes shahii WAL 8301 CBK64867.1 D4IPK5  
 CDL62_05640   Alkalitalea saponilacus DSM 24412 ASB48659.1    
 CDL62_12350   Alkalitalea saponilacus DSM 24412 ASB51153.1    
 CDL62_06155   Alkalitalea saponilacus DSM 24412 ASB48748.1    
 CDL62_06290   Alkalitalea saponilacus DSM 24412 ASB51079.1    
 CDL62_06315   Alkalitalea saponilacus DSM 24412 ASB51081.1    
 SAMN04489726_2253   Allokutzneria albata DSM 44149 SDM56136.1    
 SAMN04489726_7485   Allokutzneria albata DSM 44149 SDN62893.1    
 AM2010_211   Altererythrobacter marensis KCTC 22370 AKM06300.1    
 A6F65_00514   Altererythrobacter namhicola JCM 16345 ANU06838.1    
 MASE_13365   Alteromonas macleodii ATCC 27126 AFS38183.1    
 ACZ81_13990   Alteromonas macleodii HOT1A3 AMN12589.1    
 AMBLS11_13320   Alteromonas macleodii str. Black Sea 11 AFT79235.1    
 AMEC673_13675   Alteromonas macleodii str. English Channel 673 AFT75421.1    
 BM527_15145   Alteromonas sp. Mex14 APD88255.1    
 B737_0853 (MalZ)   Amycolatopsis mediterranei RB AGT81517.1    
 RAM_04360   Amycolatopsis mediterranei S699 AEK39364.1
AFO74388.1
   
 AMED_0854 (MalZ)   Amycolatopsis mediterranei U32 ADJ42674.1 D8I273  
 SAMN00777080_2897   Aquiflexum balticum DSM 16537 SMD44277.1    
 A9P82_05620   Arachidicoccus sp. BS20 ANI88812.1    
 A9P82_14250   Arachidicoccus sp. BS20 ANI90348.1    
 Astex_0006   Asticcacaulis excentricus CB 48 ADU11710.1 C5SHW3  
 Astex_2590   Asticcacaulis excentricus CB 48 ADU14235.1 C5SKS4  
 Astex_3626   Asticcacaulis excentricus CB 48 ADU15254.1 C5SMW1  
 ACG10_20575   Azotobacter chroococcum B3 ASL28452.1    
 Achr_40150   Azotobacter chroococcum NCIMB 8003 AJE23400.1    
 AvCA_51780   Azotobacter vinelandii CA AGK15757.1    
 AvCA6_51780   Azotobacter vinelandii CA6 AGK22431.1    
 Avin_51780   Azotobacter vinelandii DJ ATCC BAA-1303 ACO81253.1 C1DMH6  
 BRDCF_05750   Bacteroidales bacterium CF AGX08161.1
AGY53752.1
   
 BRDCF_07720   Bacteroidales bacterium CF AGX08548.1
AGY54140.1
   
 CGC64_05280   Bacteroides caccae ATCC 43185 ASM67810.1    
 CGC64_02445   Bacteroides caccae ATCC 43185 ASM64931.1    
 CGC64_12475   Bacteroides caccae ATCC 43185 ASM66687.1    
 CGC64_17265   Bacteroides caccae ATCC 43185 ASW16374.1    
 A4V03_04345   Bacteroides caecimuris I48 ANU56900.1    
 A4V03_14920   Bacteroides caecimuris I48 ANU59870.1    
 A4V03_00195   Bacteroides caecimuris I48 ANU56184.1    
 A4V03_05630   Bacteroides caecimuris I48 ANU57107.1    
 A4V03_00435   Bacteroides caecimuris I48 ANU59602.1    
 A4V03_14930   Bacteroides caecimuris I48 ANU58697.1    
 A4V03_14780   Bacteroides caecimuris I48 ANU58672.1    
 A4V03_01745   Bacteroides caecimuris I48 ANU56448.1    
 BcellWH2_02840   Bacteroides cellulosilyticus WH2 ALJ60079.1    
 BcellWH2_04836   Bacteroides cellulosilyticus WH2 ALJ62045.1    
 BcellWH2_01208   Bacteroides cellulosilyticus WH2 ALJ58470.1    
 BcellWH2_03180   Bacteroides cellulosilyticus WH2 ALJ60417.1    
 BcellWH2_02703   Bacteroides cellulosilyticus WH2 ALJ59942.1    
 BcellWH2_02844   Bacteroides cellulosilyticus WH2 ALJ60083.1    
 BcellWH2_04359   Bacteroides cellulosilyticus WH2 ALJ61576.1    
 BcellWH2_02435   Bacteroides cellulosilyticus WH2 ALJ59674.1    
 BcellWH2_01209   Bacteroides cellulosilyticus WH2 ALJ58471.1    
 BcellWH2_04493   Bacteroides cellulosilyticus WH2 ALJ61709.1    
 BcellWH2_04264   Bacteroides cellulosilyticus WH2 ALJ61481.1    
 BcellWH2_01651   Bacteroides cellulosilyticus WH2 ALJ58904.1    
 BcellWH2_02002   Bacteroides cellulosilyticus WH2 ALJ59247.1    
 BcellWH2_04823   Bacteroides cellulosilyticus WH2 ALJ62032.1    
 BcellWH2_05314   Bacteroides cellulosilyticus WH2 ALJ62516.1    
 ABI39_05915   Bacteroides dorei CL03T12C01 AND19026.1    
 ABI39_00570   Bacteroides dorei CL03T12C01 AND18133.1    
 ABI39_03470   Bacteroides dorei CL03T12C01 AND18607.1    
 ABI39_04435   Bacteroides dorei CL03T12C01 AND18771.1    
 ABI39_06580   Bacteroides dorei CL03T12C01 AND19139.1    
 ABI39_00700   Bacteroides dorei CL03T12C01 AND21694.1    
 ABI39_00725   Bacteroides dorei CL03T12C01 AND18159.1    
 ABI39_03280   Bacteroides dorei CL03T12C01 AND18575.1    
 EL88_22475   Bacteroides dorei isolate HS1_L1_B_010 AII65747.1    
 EL88_16390   Bacteroides dorei isolate HS1_L1_B_010 AII64637.1    
 EL88_01705   Bacteroides dorei isolate HS1_L1_B_010 AII61976.1    
 EL88_24865   Bacteroides dorei isolate HS1_L1_B_010 AII66187.1    
 EL88_23030   Bacteroides dorei isolate HS1_L1_B_010 AII65847.1    
 EL88_24165   Bacteroides dorei isolate HS1_L1_B_010 AII66056.1    
 GV66_00615   Bacteroides dorei isolate HS1_L3_B_079 AII66307.1    
 GV66_03285   Bacteroides dorei isolate HS1_L3_B_079 AII66800.1    
 GV66_00755   Bacteroides dorei isolate HS1_L3_B_079 AII66333.1    
 GV66_06115   Bacteroides dorei isolate HS1_L3_B_079 AII67306.1    
 GV66_04495   Bacteroides dorei isolate HS1_L3_B_079 AII67018.1    
 GV66_00780   Bacteroides dorei isolate HS1_L3_B_079 AII66338.1    
 GV66_03515   Bacteroides dorei isolate HS1_L3_B_079 AII66841.1    
 GV66_06820   Bacteroides dorei isolate HS1_L3_B_079 AII67435.1    
 IY41_00580   Bacteroides dorei isolate HS2_L_2_B_045b ALA72156.1    
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