Activities in Family	Oligoxyloglucan reducing-end-specific cellobiohydrolase (EC 3.2.1.150); Xyloglucan-specific endo-β-1,4-glucanase / endo-xyloglucanase (EC 3.2.1.151); Endo-β-1,4-glucanase (EC 3.2.1.4);
Mechanism	Inverting e
3D Structure Status	7-fold β-propeller
Catalytic Nucleophile/Base	Asp (experimental)
Catalytic Proton Donor	Asp (experimental)
External resources	CAZypedia;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (1567); Uniprot accession (35); PDB accession (19); 3D entries (12); cryst (0)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
RO1_07700		Roseburia intestinalis XB6B4	CBL11475.1
H8S51_012125		Roseburia rectibacter NSJ-69	UMY99052.1
exo-xyloglucanase 74A (Ccel_1207) (Xgh74A)	3.2.1.151	Ruminiclostridium cellulolyticum H10	ACL75564.1	B8I0I9
EHE19_003140		Ruminiclostridium herbifermentans MA18	QNU67529.1
P0092_16090		Ruminiclostridium papyrosolvens DSM 2782	WES33271.1
endo-xyloglucanase (Rumal_0030)	3.2.1.151	Ruminococcus albus 7 = DSM 20455	ADU20593.1	E0L8C0 E6UB52
endo-xyloglucanase (Rumal_2744)	3.2.1.151	Ruminococcus albus 7 = DSM 20455	ADU23213.1	E0L621 E6UHD5
RBI_I01949		Ruminococcus bicirculans (ex Wegman et al. 2014) 80/3	CCO05647.1
RBI_II00142		Ruminococcus bicirculans (ex Wegman et al. 2014) 80/3	CCO05916.1
RUM_03220		Ruminococcus champanellensis 18P13 = JCM 17042	CBL16561.1
xyloglucanase (GH74A;RUM_02790) (Xeg74A)	3.2.1.151	Ruminococcus champanellensis 18P13 = JCM 17042	CBL16522.1	D4LA77
GCM10017745_71120		Saccharothrix mutabilis subsp. capreolus JCM 4248	BFE53685.1
IOD16_08895		Saccharothrix sp. 6-C	QQQ78551.1
L3Q67_29625		Saccharothrix sp. AJ9571	UJW29381.1
EKG83_11690		Saccharothrix syringae NRRL B-16468	QFZ18055.1
SAMD00079811_68890		Scytonema sp. HK-05 NIES-2130	BAY49260.1
LS482_07290		Sinomicrobium kalidii HD2P242	UGU17672.1
L2B55_14510 (fragment)		Solitalea lacus S2-8	UKJ06737.1
O7623_11060		Solwaraspora sp. WMMD791	WFE29683.1
O7621_26205		Solwaraspora sp. WMMD937	WFE21299.1
SAMIE_1032090		Sphingobium amiense DSM 16289	BBD99708.1
C1T17_07235		Sphingobium sp. SCG-1	AUW60143.1
H3V42_13635		Sphingobium yanoikuyae A3	QNG48473.1
EBF16_10060		Sphingobium yanoikuyae SJTF8	AYO77207.1
PBT88_15355		Sphingomonas abietis PAMB00755	WBO21545.1
NEF64_12370		Sphingomonas aerolata PDD-32b-11	USQ99237.1
NEF64_08845		Sphingomonas aerolata PDD-32b-11	USR01891.1
H3Z74_12325 (fragment)		Sphingomonas alpina S8-3T	QNQ11994.1
G4G27_11120 (fragment)		Sphingomonas alpina So64.6b	QNA86927.1
LZK98_10300		Sphingomonas cannabina DM2-R-LB4	UIJ47296.1
M1K48_08370		Sphingomonas glaciei S8-45	UUR06971.1
M1K48_08360		Sphingomonas glaciei S8-45	UUR06969.1
V6R86_05100		Sphingomonas kaistensis MA4R	WWM70074.1
V6R86_05120		Sphingomonas kaistensis MA4R	WWM70078.1
LHA26_00645		Sphingomonas morindae NBD5	USI73021.1
G7077_09685 (fragment)		Sphingomonas piscis HDW15B	QIK79127.1
G7077_09690		Sphingomonas piscis HDW15B	QIK79128.1
H9L12_00235		Sphingomonas rhizophila KACC 19189	QNN66106.1
DM450_21105		Sphingomonas sp. IC081	QDK35254.1
M8312_03235		Sphingomonas sp. KRR8	URD61544.1
E5673_04505		Sphingomonas sp. PAMC26645	QCB41573.1
OIM94_09640		Sphingomonas sp. R1	UYY75802.1
OKW76_04375		Sphingomonas sp. S1-29	UZK70288.1
LZ586_04400		Sphingomonas sp. S2-65	UYY59331.1
MC45_12315 (fragment)		Sphingomonas taxi ATCC 55669	AIT08203.1
SKP52_11655		Sphingopyxis fribergensis Kp5.2	AJA09228.1
KNJ79_12150		Sphingopyxis indica MC4	WOF41982.1
AOA14_16345		Sphingopyxis terrae subsp. terrae NBRC 15098 203-1	AMU96175.1
HBA51_09185		Sphingopyxis terrae subsp. terrae YC-JH3	QXF12307.1
ETR14_04585		Sphingosinicella sp. BN140058	QAY79713.1
ETR14_13900		Sphingosinicella sp. BN140058	QAY79903.1
G5C33_10785		Sphingosinithalassobacter tenebrarum zrk23	QIG81901.1
Spith_0372		Spirochaeta thermophila DSM 6578	AEJ60657.1
POS15_09730		Stenotrophomonas sp. BIO128-Bstrain	WIA63470.1
BIZ42_16815		Stenotrophomonas sp. LM091	AOX63703.1
GXP74_17780		Streptacidiphilus sp. P02-A3a	QMU69818.1
EKD16_01545		Streptomonospora litoralis M2	QBI52126.1
DMT42_31565		Streptomyces actuosus ATCC 25421	AWT46391.1
K1J60_12430		Streptomyces akebiae MG28	QYX77223.1
K1J60_07355		Streptomyces akebiae MG28	QYX76350.1
CP975_02965		Streptomyces alboniger ATCC 12461	QEV16598.1
H9W91_31025		Streptomyces alfalfae XN-04	QUI34790.1
SAM23877_6249		Streptomyces ambofaciens ATCC 23877	AKZ59294.1
SAM40697_5606		Streptomyces ambofaciens DSM 40697	ANB09562.1
HCX60_28305		Streptomyces antibioticus DSM 41481	QIT46948.1
QR300_09210		Streptomyces antimycoticus FIM95-F1	WJE02092.1
HKX69_05260		Streptomyces argyrophyllae Jing01	QJS09000.1
G9272_36360		Streptomyces asoensis H2S5	QJT05105.1
G9272_32670		Streptomyces asoensis H2S5	QJT04466.1
CD934_08635		Streptomyces asterosporus DSM 41452	QDI68745.1
CD934_04285		Streptomyces asterosporus DSM 41452	QDI67974.1
endo-xyloglucanase (SatGH74)	3.2.1.151	Streptomyces atroolivaceus	WP_033303664.1
O1Q96_32735		Streptomyces aurantiacus Qhu-M197	WAU84037.1
O1Q96_35670		Streptomyces aurantiacus Qhu-M197	WAU84567.1
BV401_35970		Streptomyces autolyticus CGMCC0516	AQA16720.1
processive endoxyloglucanase (SaGH74A;SAV1856;SAV_1856)	3.2.1.151	Streptomyces avermitilis MA-4680 = NBRC 14893	BAC69567.1 NP_823032.1	Q82M04
endoxyloglucanase (SaGH74B;SAV2574;SAV_2574)	3.2.1.151	Streptomyces avermitilis MA-4680 = NBRC 14893	BAC70285.1 NP_823750.1	Q82K30
SAVMC3_22110 (fragment)		Streptomyces avermitilis MC3	BBJ49582.1
SAVMC3_30060		Streptomyces avermitilis MC3	BBJ50377.1
SBI_02512		Streptomyces bingchenggensis BCW-1	ADI05633.1
SBI_09975 (short fragment)		Streptomyces bingchenggensis BCW-1	ADI13093.1
EJC51_34575		Streptomyces brunneus CR22	AZP20751.1
EJC51_38240		Streptomyces brunneus CR22	AZP21411.1
EJC51_44640		Streptomyces brunneus CR22	AZP22547.1
EJC51_26025		Streptomyces brunneus CR22	AZP19221.1
IHE65_06885		Streptomyces caniscabiei ID-03-3A	WEO22892.1
IHE65_20935		Streptomyces caniscabiei ID-03-3A	WEO25452.1
IHE65_11855		Streptomyces caniscabiei ID-03-3A	WEO23813.1
OG925_24125		Streptomyces canus NBC_01585	WSD87199.1
OG925_10890		Streptomyces canus NBC_01585	WSD84761.1
OG925_15730		Streptomyces canus NBC_01585	WSD85655.1
N0X72_03410		Streptomyces carpaticus SCPM-O-B-9993	UWM48133.1
PYS65_05125		Streptomyces sp. HUAS 5	WGD39570.1
NRO40_10370		Streptomyces changanensis HL-66	UUS34776.1
NRO40_01525		Streptomyces changanensis HL-66	UUS29644.1
CP983_12290		Streptomyces chartreusis ATCC 14922	QEV67376.1
CP983_07825		Streptomyces chartreusis ATCC 14922	QEV66589.1
HUT05_13765		Streptomyces chartreusis NA02069	QKZ18333.1
HUT05_09130		Streptomyces chartreusis NA02069	QKZ17496.1
STRCI_005886		Streptomyces cinnabarinus DSM 40467	WAZ24466.1
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