Glycoside Hydrolase Family 74

Activities in Familyendoglucanase (EC 3.2.1.4); oligoxyloglucan reducing end-specific cellobiohydrolase (EC 3.2.1.150); xyloglucanase (EC 3.2.1.151)
Mechanism Inverting
3D Structure Status7-fold β-propeller
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorAsp (experimental)
External resourcesCAZypedia;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (408); Uniprot accession (70); PDB accession (12); 3D entries (8); cryst (1)
All (370) Bacteria (346) Eukaryota (21) unclassified (3) Structure (8 - 1 cryst) Characterized (17)
| 1 | 2 | 3 | 4 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 avicelase (AviIII;AcGH74;Acel_0618) (Cel74A) 3.2.1.- Acidothermus cellulolyticus 11B ABK52391.1
ACE14916.1
ACE14917.1
ACE14920.1
ACS09146.1
ACS09147.1
ACS09150.1
A0LSI1 4LGN[A]
 AHOG_16935   Actinoalloteichus hoggarensis DSM 45943 ASO21013.1    
 TL08_15525   Actinoalloteichus hymeniacidonis HPA177(T) (=DSM 45092(T)) AOS63914.1    
 UA74_18915   Actinoalloteichus sp. ADI127-7 APU15811.1    
 UA75_19405   Actinoalloteichus sp. GBA129-24 APU21871.1    
 SAMN04489716_3664   Actinoplanes derwentensis DSM 43941 SDT40981.1    
 AFR_18920   Actinoplanes friuliensis DSM 7358 AGZ42058.1    
 L083_5389   Actinoplanes sp. N902-109 AGL18899.1    
 ACPL_2582   Actinoplanes sp. SE50/110 AEV83477.1
SLL99278.1
   
 Amir_1791   Actinosynnema mirum DSM 43827 ACU35739.1 C6WCX2  
 CNX65_08935   Actinosynnema pretiosum X47 ATE53401.1    
 B737_8369   Amycolatopsis mediterranei RB AGT89030.1    
 B737_5117   Amycolatopsis mediterranei RB AGT85781.1    
 RAM_26385   Amycolatopsis mediterranei S699 AEK43754.1
AFO78653.1
   
 AMES_8368   Amycolatopsis mediterranei S699 AFO81901.1
AEK47190.1
   
 AMED_5179   Amycolatopsis mediterranei U32 ADJ46942.1 D8I1L1  
 AMED_8497   Amycolatopsis mediterranei U32 ADJ50193.1 D8HJB6  
 Astex_1379   Asticcacaulis excentricus CB 48 ADU13049.1 C5SMT3  
 AXW83_18510   Bosea sp. PAMC 26642 AMJ63794.1    
 SAMN05444169_5174   Bradyrhizobium erythrophlei GAS242 SHG99641.1    
 SAMN05444169_5168   Bradyrhizobium erythrophlei GAS242 SHG99512.1    
 A4249_02030   Brevundimonas sp. GW460-12-10-14-LB2 ANC52564.1    
 BamMC406_4813   Burkholderia ambifaria MC40-6 ACB67266.1 B1YYN0  
 BCCH1_00860   Burkholderia contaminans CH-1 BBA37676.1    
 NL30_17635   Burkholderia contaminans MS14 AKM41778.1    
 WI95_29870   Burkholderia lata FL-1-2-30-S1-D0 AOL08033.1    
 Athe_1860   Caldicellulosiruptor bescii DSM 6725 ACM60948.1 B9MKU0  
 Calkr_0017   Caldicellulosiruptor kristjanssonii I77R1B ADQ39606.1 E4S5E5  
 Calkro_0861   Caldicellulosiruptor kronotskyensis 2002 ADQ45737.1 E4SDC8  
 Calla_0015   Caldicellulosiruptor lactoaceticus 6A AEM72711.1    
 Calla_2311   Caldicellulosiruptor lactoaceticus 6A AEM74844.1    
 COB47_1664   Caldicellulosiruptor obsidiansis OB47 ADL42945.1 D9TFH5  
 Csac_1085 (fragment)   Caldicellulosiruptor saccharolyticus DSM 8903 ABP66699.1 A4XIG4  
 ORF5   Caldicellulosiruptor sp. Tok7B.1 AAK06388.1
AAK06391.1
Q9AQH0  
 NIES22_50990 (XghA)   Calothrix brevissima NIES-22 BAY64998.1    
 NIES267_03280   Calothrix parasitica NIES-267 BAY80863.1    
 NIES267_20470   Calothrix parasitica NIES-267 BAY82565.1    
 NIES2100_48060   Calothrix sp. NIES-2100 BAY25007.1    
 NIES3974_11410 (XghA)   Calothrix sp. NIES-3974 BAZ04502.1    
 NIES4071_99540 (Xgha_2)   Calothrix sp. NIES-4071 BAZ18072.1    
 NIES4101_69480 (Xgha_2)   Calothrix sp. NIES-4101 BAZ40986.1    
 NIES4101_20300 (Xgha_1)   Calothrix sp. NIES-4101 BAZ36127.1    
 NIES4105_99470 (Xgha_2)   Calothrix sp. NIES-4105 BAZ64217.1    
 Cal6303_0525   Calothrix sp. PCC 6303 AFY99599.1    
 Cal7507_0494   Calothrix sp. PCC 7507 AFY30989.1    
 Cal7507_2262   Calothrix sp. PCC 7507 AFY32698.1    
 Caci_6682   Catenulispora acidiphila DSM 44928 ACU75528.1 C7Q035  
 Celf_1913   Cellulomonas fimi ATCC 484 AEE46043.1    
 Celgi_3134   Cellulomonas gilvus ATCC 13127 AEI13625.1    
 CBP52_13515   Cellulomonas sp. PSBB021 ASR55945.1    
 CJA_2477 (Gly74A)   Cellvibrio japonicus Ueda107 ACE84745.1 B3PKK9 5FKQ[A,B]
5FKR[A]
5FKS[A]
5FKT[A,B]
 CAC0919   Clostridium acetobutylicum ATCC 824 AAK78895.1
NP_347555.1
Q97KK0  
 SMB_G0936   Clostridium acetobutylicum DSM 1731 AEI31501.1    
 CEA_G0931   Clostridium acetobutylicum EA 2018 ADZ19970.1    
 CM240_3328 (XghA) (partial)   Clostridium bornimense M2/40 CDM70445.1    
 Ccel_1207   [Clostridium] cellulolyticum H10 ACL75564.1 B8I0I9  
 sialidase (SiaA)   Clostridium cellulovorans BAV13158.1    
 Clocel_3459   Clostridium cellulovorans 743B ADL53137.1 D9SVS6  
 Clocl_0906   [Clostridium] clariflavum DSM 19732 AEV67584.1    
 Clole_2677   Clostridium lentocellum DSM 5427 ADZ84378.1    
 Clole_3660   Clostridium lentocellum DSM 5427 ADZ85343.1    
 Cspa_c18560   Clostridium saccharoperbutylacetonicum N1-4(HMT) AGF55626.1    
 CLSAP_17870   Clostridium saccharoperbutylacetonicum N1-504 AQR94478.1    
 Clo1100_2840   Clostridium sp. BNL1100 AEY66994.1    
 CAter282_2329   Collimonas arenae Ter282 AMP10077.1    
 CFU_2655 (CelA)   Collimonas fungivorans Ter331 AEK62482.1    
 CFter6_0469   Collimonas fungivorans Ter6 AMO93200.1    
 CFter6_3378   Collimonas fungivorans Ter6 AMO96012.1    
 CPter291_0340 (fragment)   Collimonas pratensis Ter291 AMP12630.1    
 CPter91_0344 (fragment)   Collimonas pratensis Ter91 AMP02743.1    
 A9D14_16965 (fragment)   Croceicoccus marinus E4A9 ARU18183.1    
 CYFUS_003582   Cystobacter fuscus DSM 52655 ATB38151.1    
 CHU_1155   Cytophaga hutchinsonii ATCC 33406 ABG58430.1 Q11VY6  
 ATSB10_09970   Dyella thiooxydans ATSB10 AND68451.1    
 EUS_21560   [Eubacterium] siraeum 70/3 CBK97166.1 D4JVP7  
 ES1_03020   [Eubacterium] siraeum V10Sc8a CBL33465.1 D4MI82  
 Fisuc_2317 / FSU_2866   Fibrobacter succinogenes subsp. succinogenes S85 ACX75903.1
ADL25499.1
C9RKV5  
 OP10G_2497   Fimbriimonas ginsengisoli Gsoil 348 AIE85865.1    
 D770_26360   Flammeovirgaceae bacterium 311 AHM63515.1    
 NIES3275_40310   Fremyella diplosiphon NIES-3275 BAY92000.1    
 GEI7407_0960   Geitlerinema sp. PCC 7407 AFY65458.1    
 GEI7407_2044   Geitlerinema sp. PCC 7407 AFY66524.1    
 GKIL_4000   Gloeobacter kilaueensis JS1 AGY60246.1    
 YC6258_03526   Gynuella sunshinyii YC6258 AJQ95562.1    
 Haur_2138   Herpetosiphon aurantiacus DSM 785 ABX04778.1 A9AWC8  
 I598_1172   Isoptericola dokdonensis DS-3 ANC30739.1    
 BN2497_4323   Janthinobacterium sp. CG23_2 CUI20386.1    
 Jden_0731   Jonesia denitrificans DSM 20603 ACV08395.1 C7R1S7  
 CEP80_01510   Jonesia denitrificans FDAARGOS_301 ASE07956.1    
 xyloglucanase (Xeg) 3.2.1.151 Jonesia DSM 14140 CAD58415.1    
 B6264_25475   Kitasatospora aureofaciens DM-1 ARF81801.1    
 Kfla_1830   Kribbella flavida DSM 17836 ADB30924.1 D2PPG2  
 LG3211_1831 (XghA)   Lysobacter gummosus 3.2.11 ALN90802.1    
 MOC_3752   Methylobacterium oryzae CBMB20 AIQ91507.1    
 MCBMB27_02741   Methylobacterium phyllosphaerae CBMB27 APT32032.1    
 A3224_13305   Microbulbifer thermotolerans DAU221 AMX03421.1    
 Mic7113_1864   Microcoleus sp. PCC 7113 AFZ17720.1    
 Mic7113_4135   Microcoleus sp. PCC 7113 AFZ19837.1    
 GA0070611_3076   Micromonospora auratinigra DSM 44815 SBT45569.1    
 GA0070614_1777   Micromonospora coxensis DSM 45161 SCG49361.1    
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