Glycoside Hydrolase Family 74

Activities in Familyendoglucanase (EC 3.2.1.4); oligoxyloglucan reducing end-specific cellobiohydrolase (EC 3.2.1.150); xyloglucanase (EC 3.2.1.151)
Mechanism Inverting
3D Structure Status7-fold β-propeller
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorAsp (experimental)
External resourcesCAZypedia;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (448); Uniprot accession (70); PDB accession (12); 3D entries (8); cryst (1)
All (410) Bacteria (385) Eukaryota (22) unclassified (3) Structure (8 - 1 cryst) Characterized (17)
| 1 | 2 | 3 | 4 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 RO1_07700   Roseburia intestinalis XB6B4 CBL11475.1 D4KVT5  
 AD2_00863   Ruminiclostridium thermocellum AD2 ALX07858.1    
 Cthe_1398 (XghA) (Xgh74A)   Ruminiclostridium thermocellum ATCC 27405 ABN52629.1 A3DFA0  
 Clo1313_0851   Ruminiclostridium thermocellum DSM 1313 ADU73920.1    
 LQRI_0862   Ruminiclostridium thermocellum DSM 2360 LQRI ANV75603.1    
 β-1,4-xyloglucan hydrolase / xyloglucanase (XghA) (Xgh74A) 3.2.1.151 Ruminiclostridium thermocellum F7/YS CAE51306.1 Q70DK5 2CN2[A,B,C,D]
2CN3[A,B]
 Rumal_0030   Ruminococcus albus 7 = DSM 20455 ADU20593.1 E0L8C0  
 Rumal_2744   Ruminococcus albus 7 = DSM 20455 ADU23213.1 E0L621  
 RBI_I01949   Ruminococcus bicirculans 80/3 CCO05647.1    
 RBI_II00142   Ruminococcus bicirculans 80/3 CCO05916.1    
 RUM_03220   Ruminococcus champanellensis 18P13 = JCM 17042 CBL16561.1 D4LAB6  
 xyloglucanase (GH74A;RUM_02790) (Xeg74A) 3.2.1.151 Ruminococcus champanellensis 18P13 = JCM 17042 CBL16522.1 D4LA77  
 SAMD00079811_68890   Scytonema sp. HK-05 NIES-2130 BAY49260.1    
 C1T17_07235   Sphingobium sp. SCG-1 AUW60143.1    
 MC45_12315 (fragment)   Sphingomonas taxi ATCC 55669 AIT08203.1    
 SKP52_11655   Sphingopyxis fribergensis Kp5.2 AJA09228.1    
 AOA14_16345   Sphingopyxis terrae NBRC 15098 203-1 AMU96175.1    
 Spith_0372   Spirochaeta thermophila DSM 6578 AEJ60657.1    
 BIZ42_16815   Stenotrophomonas sp. LM091 AOX63703.1    
 SAM23877_6249   Streptomyces ambofaciens ATCC 23877 AKZ59294.1    
 SAM40697_5606   Streptomyces ambofaciens DSM 40697 ANB09562.1    
 BV401_35970   Streptomyces autolyticus CGMCC0516 AQA16720.1    
 processive endoxyloglucanase (SaGH74A;SAV1856;SAV_1856) 3.2.1.151 Streptomyces avermitilis MA-4680 = NBRC 14893 BAC69567.1
NP_823032.1
   
 endoxyloglucanase (SaGH74B;SAV2574;SAV_2574) 3.2.1.151 Streptomyces avermitilis MA-4680 = NBRC 14893 BAC70285.1
NP_823750.1
   
 SBI_02512   Streptomyces bingchenggensis BCW-1 ADI05633.1 D7BYS4  
 SBI_09975 (short fragment)   Streptomyces bingchenggensis BCW-1 ADI13093.1 D7CF77  
 xyloglucan-specific endo-β-1,4-glucanase (SCO6545) 3.2.1.151 Streptomyces coelicolor A3(2) CAA20642.1
NP_630626.1
O86727  
 TU94_23985   Streptomyces cyaneogriseus subsp. noncyanogenus NMWT 1 AJP04078.1    
 TU94_27790   Streptomyces cyaneogriseus subsp. noncyanogenus NMWT 1 AJP04697.1    
 BN159_1888 (Xeg74)   Streptomyces davaonensis JCM 4913 CCK26267.1    
 BN159_3333   Streptomyces davaonensis JCM 4913 CCK27712.1    
 SGLAU_24475   Streptomyces glaucescens GLA.O AIS00837.1    
 SGLAU_27575 (Xeg74)   Streptomyces glaucescens GLA.O AIS01453.1    
 SHJG_7497   Streptomyces hygroscopicus subsp. jinggangensis 5008 AEY92764.1    
 SHJGH_7257   Streptomyces hygroscopicus subsp. jinggangensis TL01 AGF66919.1    
 SHL15_6374   Streptomyces hygroscopicus subsp. limoneus KCTC 1717 ALO97410.1    
 SHXM_02550   Streptomyces hygroscopicus XM201 AQW49087.1    
 ABB07_10545   Streptomyces incarnatus NRRL 8089 AKJ10441.1    
 SIRAN2237   Streptomyces iranensis CDR05273.1    
 Sle_12360   Streptomyces leeuwenhoekii C34 (= DSM 42122 = NRRL B-24963) CQR60698.1    
 Sle_19940   Streptomyces leeuwenhoekii C34 (= DSM 42122 = NRRL B-24963) CQR61455.1    
 SLINC_0652   Streptomyces lincolnensis NRRL 2936 ANS62876.1    
 SLINC_6104   Streptomyces lincolnensis NRRL 2936 ANS68328.1    
 SLINC_4524   Streptomyces lincolnensis NRRL 2936 ANS66748.1    
 SLINC_6965   Streptomyces lincolnensis NRRL 2936 ANS69189.1    
 SLIV_05700 (Xeg74)   Streptomyces lividans TK24 AIJ12155.1    
 SMALA_6401   Streptomyces malaysiensis DSM 4137 ATL86629.1    
 SNOD_27125   Streptomyces nodosus ATCC 14899 AJE43290.1    
 B1H29_06335   Streptomyces pactum ACT12 AQS66595.1    
 B1H29_10285   Streptomyces pactum ACT12 AQS67263.1    
 Sfla_0768   Streptomyces pratensis ATCC 33331 ADW02230.1 C9NF58  
 Sfla_5707   Streptomyces pratensis ATCC 33331 ADW07099.1 C9NK37  
 SPRI_6747   Streptomyces pristinaespiralis HCCB 10218 ALC25053.1    
 SPRI_1936   Streptomyces pristinaespiralis HCCB 10218 ALC20242.1    
 M271_10845   Streptomyces rapamycinicus NRRL 5491 AGP53770.1    
 TUE45_06390   Streptomyces reticuli CUW31642.1    
 TUE45_07138   Streptomyces reticuli CUW32389.1    
 TUE45_06392   Streptomyces reticuli CUW31644.1    
 A4G23_00138   Streptomyces rubrolavendulae MJM4426 AOT57352.1    
 SCAB_17021   Streptomyces scabiei 87.22 CBG68834.1 C9ZEQ1  
 SCAB_25591   Streptomyces scabiei 87.22 CBG69665.1 C9Z273  
 SCAB_43081   Streptomyces scabiei 87.22 CBG71378.1 C9Z5M3  
 CGL27_37920   Streptomyces sp. 11-1-2 ASR00580.1    
 SAMN05428941_6615   Streptomyces sp. 2114.2 SDT79105.1    
 SAMN05444521_1742   Streptomyces sp. 3214.6 SHH75378.1    
 SAMN05444521_4284   Streptomyces sp. 3214.6 SHI13200.1    
 SAMN05444521_2494   Streptomyces sp. 3214.6 SHH90159.1    
 ASR50_29355   Streptomyces sp. 4F ALV53117.1    
 C2142_19045   Streptomyces sp. CB01881 AUY50695.1    
 NI25_05675   Streptomyces sp. CCM_MD2014 AIV33080.1    
 AS200_10480   Streptomyces sp. CdTB01 ALV32417.1    
 AA958_12255 (fragment)   Streptomyces sp. CNQ-509 AKH82879.1    
 B1K54_27340   Streptomyces sp. fd1-xmd AQT74869.1    
 CFP59_02213   Streptomyces sp. M56 AUA10116.1    
 C6376_01020   Streptomyces sp. P3 AVV40214.1    
 C6376_43635   Streptomyces sp. P3 AVV47194.1    
 C6376_33430   Streptomyces sp. P3 AVV45536.1    
 F750_6092   Streptomyces sp. PAMC 26508 AGJ58519.1    
 F750_0883   Streptomyces sp. PAMC 26508 AGJ53394.1    
 QR97_23545   Streptomyces sp. PBH53 AKN72348.1    
 QR97_23535   Streptomyces sp. PBH53 AKN72346.1    
 QR97_14000   Streptomyces sp. PBH53 AKN70777.1    
 QR97_26710 (fragment)   Streptomyces sp. PBH53 AKN72870.1    
 A4E84_33650   Streptomyces sp. S10(2016) AMW14005.1    
 A4E84_29040   Streptomyces sp. S10(2016) AMW13186.1    
 CAG99_25100   Streptomyces sp. SCSIO 03032 ARQ72631.1    
 SACTE_0562   Streptomyces sp. SirexAA-E AEN08502.1   5JWZ[A,B]
 B9S64_01665   Streptomyces sp. SM18 AWL36969.1    
 SVEN_2582   Streptomyces venezuelae ATCC 10712 CCA55868.1    
 SVEN_6747   Streptomyces venezuelae ATCC 10712 CCA60033.1    
 BN2537_11007   Streptomyces venezuelae ATCC 15439 CUM41021.1    
 AQF52_3012   Streptomyces venezuelae ATCC 15439 ALO08606.1    
 SVTN_34290   Streptomyces vietnamensis GIM4.0001 AJF68658.1    
 Strvi_2933   Streptomyces violaceusniger Tu 4113 AEM82630.1    
 SXIM_04340   Streptomyces xiamenensis 318 AKG41818.1    
 Sros_2492   Streptosporangium roseum DSM 43021 ACZ85468.1 D2B2Y8  
 TERTU_3347   Teredinibacter turnerae T7901 ACR14174.1 C5BQL1  
 xyloglucanase (Tfu_1612) (Xeg74) 3.2.1.151 Thermobifida fusca YX AAZ55647.1
ZP_00056977.1
Q47PH2 1WWO[nd]
 Tbis_1219   Thermobispora bispora DSM 43833 ADG87940.1 D6Y8P3  
 endo-β-1,4-glucanase (TM0305) (Cel74) 3.2.1.4 Thermotoga maritima MSB8 AAD35393.1
AGL49229.1
AHD17931.1
AKE28106.1
NP_228117.1
Q9WYE1  
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