Glycoside Hydrolase Family 6

Activities in Familyendoglucanase (EC 3.2.1.4); cellobiohydrolase (EC 3.2.1.91)
Mechanism Inverting
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorAsp (experimental)
Noteformerly known as cellulase family B. The cellobiohydrolases of this family are widely believed to act processively from the non-reducing ends of cellulose chains to generate cellobiose.
External resourcesCAZypedia; HOMSTRAD; MEGAZYME; PRINTS; PROSITE;
Statistics GenBank accession (1333); Uniprot accession (242); PDB accession (52); 3D entries (13); cryst (0)
All (1241) Bacteria (1051) Eukaryota (187) unclassified (3) Structure (13) Characterized (66)
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Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 B9S66_22680   Streptomyces sp. SM17 AWL34808.1    
 B9S66_21020   Streptomyces sp. SM17 AWL34502.1    
 B9S64_00355   Streptomyces sp. SM18 AWL36738.1    
 B9S64_11215   Streptomyces sp. SM18 AWL38618.1    
 exo 1,4-beta glucanase (Exo14)   Streptomyces sp. TBG-MR17 AVX33663.1    
 SAMN05216371_0488   Streptomyces sp. TLI_053 SDS72578.1    
 SAMN05216371_5082   Streptomyces sp. TLI_053 SDT76023.1    
 BSL84_23150   Streptomyces sp. TN58 APU42241.1    
 TK78_09300   Streptomyces sp. Tue 6075 Tue6075 APS19134.1    
 TK78_22555   Streptomyces sp. Tue 6075 Tue6075 APS21393.1    
 TK78_29895   Streptomyces sp. Tue 6075 Tue6075 APS22683.1    
 C5L38_04490   Streptomyces sp. WAC00288 AVH94410.1    
 C4B68_25425   Streptomyces sp. XZHG99 AVH58554.1    
 C4B68_33615   Streptomyces sp. XZHG99 AVH59891.1    
 DDQ41_11315   Streptomyces spongiicola HNM0071 AWK09415.1    
 DDQ41_07750   Streptomyces spongiicola HNM0071 AWK08831.1    
 SVEN_6713   Streptomyces venezuelae ATCC 10712 CCA59999.1    
 SVEN_6595 (fragment)   Streptomyces venezuelae ATCC 10712 CCA59881.1    
 SVEN_6712   Streptomyces venezuelae ATCC 10712 CCA59998.1    
 SVEN_5064+SVEN_5063   Streptomyces venezuelae ATCC 10712 CCA58349.1
CCA58350.1
   
 BN2537_3231   Streptomyces venezuelae ATCC 15439 CUM37133.1    
 BN2537_10939   Streptomyces venezuelae ATCC 15439 CUM40987.1    
 BN2537_5745   Streptomyces venezuelae ATCC 15439 CUM38390.1    
 BN2537_15925   Streptomyces venezuelae ATCC 15439 CUM43480.1    
 BN2537_15927   Streptomyces venezuelae ATCC 15439 CUM43481.1    
 AQF52_5510   Streptomyces venezuelae ATCC 15439 ALO11104.1    
 AQF52_0673   Streptomyces venezuelae ATCC 15439 ALO06270.1    
 AQF52_6683   Streptomyces venezuelae ATCC 15439 ALO12276.1    
 AQF52_3044   Streptomyces venezuelae ATCC 15439 ALO08638.1    
 AQF52_0674   Streptomyces venezuelae ATCC 15439 ALO06271.1    
 SVTN_36755   Streptomyces vietnamensis GIM4.0001 AJF69026.1    
 SVTN_32835   Streptomyces vietnamensis GIM4.0001 AJF68425.1    
 SVTN_36760   Streptomyces vietnamensis GIM4.0001 AJF69027.1    
 B1H20_00285   Streptomyces violaceoruber S21 ARF59988.1    
 B1H20_25425   Streptomyces violaceoruber S21 ARF64351.1    
 Strvi_1875   Streptomyces violaceusniger Tu 4113 AEM81610.1    
 Strvi_6722   Streptomyces violaceusniger Tu 4113 AEM86102.1    
 Strvi_8132   Streptomyces violaceusniger Tu 4113 AEM87455.1    
 Strvi_8233   Streptomyces violaceusniger Tu 4113 AEM87553.1    
 Strvi_8932   Streptomyces violaceusniger Tu 4113 AEM88233.1    
 Strvi_2397   Streptomyces violaceusniger Tu 4113 AEM82121.1    
 SXIM_43350   Streptomyces xiamenensis 318 AKG45719.1    
 SXIM_39640   Streptomyces xiamenensis 318 AKG45348.1    
 SXIM_39610   Streptomyces xiamenensis 318 AKG45345.1    
 SXIM_47450   Streptomyces xiamenensis 318 AKG46129.1    
 cellobiohydrolase (Cbh) (fragment)   Streptomyces xylophagus KX6 ADK32332.1 E2GJC5  
 Sros_3907   Streptosporangium roseum DSM 43021 ACZ86824.1 D2AUW2  
 Sros_6407   Streptosporangium roseum DSM 43021 ACZ89121.1 D2B0B5  
 Sros_6890   Streptosporangium roseum DSM 43021 ACZ89593.1 D2B768  
 TERTU_2895 (CelA)   Teredinibacter turnerae T7901 ACR12145.1 C5BNA9  
 TERTU_3996   Teredinibacter turnerae T7901 ACR14000.1 C5BTS3  
 TERTU_2898   Teredinibacter turnerae T7901 ACR12723.1 C5BNB1  
 bifunctional β-1,4-endoglucanase / cellobiohydrolase (CelAB) 3.2.1.4
3.2.1.91
Teredinibacter turnerae T7901 ABS72374.1 A9Q634  
 RPIT_07825   Tessaracoccus flavus RP1T AQP44725.1    
 BKM78_08455   Tessaracoccus sp. T2.5-30 AQX15944.1    
 cellulase (Cel6A)   Thermoactinospora rubra YIM 77501 ALR99813.1    
 endo-1,4-beta glucanase E2   Thermobifida alba AHK119 BBA57843.1    
 cellobiohydrolase 6B / exoglucanase (E3;Ex;Tfu_0620) (Cel6B) 3.2.1.91 Thermobifida fusca YX AAA62211.1
AAF75786.1
AAZ54658.1
ABH87632.1
Q47SA9
Q60029
Q9KH72
4AVN[A]
4AVO[A]
4B4F[A,B]
4B4H[A,B]
 endo-β-1,4-glucanase (E2;CelB;Tfu_1074) (Cel6A) 3.2.1.4 Thermobifida fusca YX AAC06388.1
AAE59940.1
AAZ55112.1
P26222
Q47R05
1TML[A]
2BOD[X]
2BOE[X]
2BOF[X]
2BOG[X]
3RU8[X]
 endoglucanase (ThCel6A) (alkali-stable) (Cel6A) 3.2.1.4 Thermobifida halotolerans YIM 90462T AHN09982.1    
 endo-β-1,4-glucanase A (CelA) 3.2.1.4 Thermobispora bispora / Microbispora bispora   P26414  
 Tbis_2830   Thermobispora bispora DSM 43833 ADG89529.1 D6Y6N8  
 Tbis_2656   Thermobispora bispora DSM 43833 ADG89357.1 D6Y5G2  
 Tcur_1738   Thermomonospora curvata DSM 43183 ACY97312.1 D1AC46  
 glycosyl hydrolase family 6 domain-containing protein, partial (fragment)   uncultured Alteromonadaceae bacterium AIF91561.1    
 endoglucanase mgCel6A (mgCel6A) 3.2.1.4 uncultured bacterium     6FAO[A]
 exo-glucanase (Exo) (fragment)   uncultured bacterium AEI54553.1    
 cellulase (Cel6H) (partial) (Cel6H) 3.2.1.4 uncultured bacterium AEK21789.1
AEK21789.2
   
 cellulase (Lc-CelB) 3.2.1.4 uncultured bacterium AHL27895.1    
 cellulase (Lc-CelJ) 3.2.1.4 uncultured bacterium AHL27903.1    
 chitinase   uncultured bacterium AZ_40 AKA59481.1    
 ORF   uncultured bacterium Contigcl_10-cl AHF25546.1    
 VAB18032_14255   Verrucosispora maris AB-18-032 AEB43963.1    
 VAB18032_29366   Verrucosispora maris AB-18-032 AEB46944.1    
 VASRM7_464   Verrucosispora sp. MS100047 AIS85704.1    
 BSQ33_03140   Vibrio gazogenes ATCC 43942 ASA54818.1    
 XALc_0484   Xanthomonas albilineans GPE PC73 CBA15018.1    
 AAW18_17430   Xanthomonas campestris pv. campestris 17 ALE70068.1    
 AAW18_15590   Xanthomonas campestris pv. campestris 17 ALE69751.1    
 AEA01_04955   Xanthomonas campestris pv. campestris 4013 AKS19350.1    
 AEA01_03090   Xanthomonas campestris pv. campestris 4013 AKS19024.1    
 AEA00_03060   Xanthomonas campestris pv. campestris ICMP 21080 AKS14997.1    
 AEA00_04910 (fragment)   Xanthomonas campestris pv. campestris ICMP 21080 AKS15321.1    
 XC_0626   Xanthomonas campestris pv. campestris str. 8004 AAY47706.1 Q4UZ17  
 XC_1005   Xanthomonas campestris pv. campestris str. 8004 AAY48079.1 Q4UXZ4  
 XCC3160   Xanthomonas campestris pv. campestris str. ATCC 33913 AAM42430.1
NP_638506.1
Q8P622  
 XCC3534   Xanthomonas campestris pv. campestris str. ATCC 33913 AAM42804.1
NP_638880.1
Q8P514  
 xcc-b100_0661   Xanthomonas campestris pv. campestris str. B100 CAP50000.1 Q8P514  
 xcc-b100_1018   Xanthomonas campestris pv. campestris str. B100 CAP50366.1    
 XCR_3498   Xanthomonas campestris pv. raphani 756C AEL08359.1    
 CKU38_00642   Xanthomonas citri pv. fuscans FX01 ATB57191.1    
 A9D66_17785   Xanthomonas citri pv. glycines str. 12-2 ARV24394.1    
 BHE84_07050   Xanthomonas citri pv. glycines str. 8ra AOY64814.1    
 XcfCFBP6167P_10405   Xanthomonas citri pv. phaseoli var. fuscans CFBP6167 ATS88656.1    
 XcfCFBP6992P_05255   Xanthomonas citri pv. phaseoli var. fuscans CFBP6992 ATS50368.1    
 XcfCFBP6994P_13980   Xanthomonas citri pv. phaseoli var. fuscans CFBP6994R ATS56103.1    
 XcfCFBP6996P_11750   Xanthomonas citri pv. phaseoli var. fuscans CFBP6996R ATS59881.1    
 XcvCFBP7112P_03250   Xanthomonas citri pv. vignicola CFBP7112 ASK95409.1    
 AXO1947_17555   Xanthomonas oryzae pv. oryzae AXO1947 ALS96036.1    
 C0L90_02955   Xanthomonas oryzae pv. oryzae BAI3 AVU01668.1    
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