Glycoside Hydrolase Family 6

Activities in Familyendoglucanase (EC 3.2.1.4); cellobiohydrolase (EC 3.2.1.91)
Mechanism Inverting
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorAsp (experimental)
Noteformerly known as cellulase family B. The cellobiohydrolases of this family are widely believed to act processively from the non-reducing ends of cellulose chains to generate cellobiose.
External resourcesCAZypedia; HOMSTRAD; MEGAZYME; PRINTS; PROSITE;
Statistics GenBank accession (1427); Uniprot accession (242); PDB accession (52); 3D entries (13); cryst (0)
All (1338) Bacteria (1148) Eukaryota (187) unclassified (3) Structure (13) Characterized (66)
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Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 SAV557 (GuxA1)   Streptomyces avermitilis MA-4680 = NBRC 14893 BAC68267.1
NP_821732.1
Q82QF2  
 SAV6896 (CelA5)   Streptomyces avermitilis MA-4680 = NBRC 14893 BAC74607.1
NP_828072.1
   
 SAV5217   Streptomyces avermitilis MA-4680 = NBRC 14893 BAC72929.1
NP_826394.1
   
 SBI_09967   Streptomyces bingchenggensis BCW-1 ADI13085.1 D7CF69  
 SBI_08394 (Nang8)   Streptomyces bingchenggensis BCW-1 ADI11512.1 D7BSL5  
 SBI_03541   Streptomyces bingchenggensis BCW-1 ADI06662.1 D7CCE3  
 SBI_05888   Streptomyces bingchenggensis BCW-1 ADI09008.1 D7CGA4  
 SBI_06715   Streptomyces bingchenggensis BCW-1 ADI09835.1 D7BXT7  
 SBI_06899 (Guxa2)   Streptomyces bingchenggensis BCW-1 ADI10019.1 D7C1F4  
 SBI_02971   Streptomyces bingchenggensis BCW-1 ADI06092.1 D7C4P1  
 SBI_09968 (fragment)   Streptomyces bingchenggensis BCW-1 ADI13086.1 D7CF70  
 SCAT_0072   Streptomyces cattleya NRRL 8057 = DSM 46488 CCB72810.1    
 SCAT_0255 (NanG)   Streptomyces cattleya NRRL 8057 = DSM 46488 CCB72993.1    
 SCAT_1903   Streptomyces cattleya NRRL 8057 = DSM 46488 CCB74622.1    
 SCATT_00750   Streptomyces cattleya NRRL 8057 = DSM 46488 AEW92446.1    
 CVT27_10720   Streptomyces cavourensis 1AS2a ATY95895.1    
 CVT27_32065   Streptomyces cavourensis 1AS2a ATY99635.1    
 CVT27_24170   Streptomyces cavourensis 1AS2a ATY98211.1    
 CVT27_22520   Streptomyces cavourensis 1AS2a ATY97915.1    
 DTW94_24360   Streptomyces cavourensis TJ430 AXI74049.1    
 DTW94_32195   Streptomyces cavourensis TJ430 AXI75461.1    
 DTW94_22630   Streptomyces cavourensis TJ430 AXI73744.1    
 ORF   Streptomyces citricolor NBRC 13005 BAV57078.1    
 D1794_19205   Streptomyces clavuligerus F1D-5 AXU14668.1    
 BB341_18385   Streptomyces clavuligerus F613-1 ANW20041.1    
 SCO6548 (SC5C7.33)   Streptomyces coelicolor A3(2) CAA20645.1
NP_630629.1
O86730  
 SCO2838 (SCE20.12c)   Streptomyces coelicolor A3(2) CAB65568.1
NP_627067.1
Q9RDB3  
 SCO1451 (SCL6.08c)   Streptomyces coelicolor A3(2) CAB76873.1
NP_625732.1
Q9L108  
 B446_30105   Streptomyces collinus Tu 365 AGS72825.1    
 TU94_27800   Streptomyces cyaneogriseus subsp. noncyanogenus NMWT 1 AJP04699.1    
 TU94_29260   Streptomyces cyaneogriseus subsp. noncyanogenus NMWT 1 AJP04932.1    
 BN159_1886 (Guxa2)   Streptomyces davaonensis JCM 4913 CCK26265.1    
 BN159_2998   Streptomyces davaonensis JCM 4913 CCK27377.1    
 BN159_5433   Streptomyces davaonensis JCM 4913 CCK29812.1    
 BN159_7136 (CasA)   Streptomyces davaonensis JCM 4913 CCK31515.1    
 C4B68_25425   Streptomyces dengpaensis XZHG99 AVH58554.1    
 C4B68_33615   Streptomyces dengpaensis XZHG99 AVH59891.1    
 KY5_5533c   Streptomyces formicae KY5 ATL30551.1    
 KY5_2990c   Streptomyces formicae KY5 ATL28008.1    
 KY5_1935c   Streptomyces formicae KY5 ATL26953.1    
 SFUL_971   Streptomyces fulvissimus DSM 40593 AGK75951.1    
 SFUL_2432   Streptomyces fulvissimus DSM 40593 AGK77382.1    
 SFUL_4876   Streptomyces fulvissimus DSM 40593 AGK79772.1    
 SFUL_5209   Streptomyces fulvissimus DSM 40593 AGK80102.1    
 SFUL_6931   Streptomyces fulvissimus DSM 40593 AGK81808.1    
 SGLAU_26660 (Guxa1)   Streptomyces glaucescens GLA.O AIS01270.1    
 SGLAU_12910   Streptomyces glaucescens GLA.O AIR98574.1    
 SGLAU_27585   Streptomyces glaucescens GLA.O AIS01455.1    
 WQO_24880   Streptomyces globisporus C-1027 ALU96272.1    
 WQO_05035   Streptomyces globisporus C-1027 ALU92764.1    
 WQO_12040   Streptomyces globisporus C-1027 ALU94015.1    
 WQO_23220   Streptomyces globisporus C-1027 ALU95973.1    
 DIJ69_08780   Streptomyces globisporus TFH56 AWL86036.1    
 DIJ69_29320   Streptomyces globisporus TFH56 AWL89477.1    
 DIJ69_22205   Streptomyces globisporus TFH56 AWL88273.1    
 DIJ69_10510   Streptomyces globisporus TFH56 AWL86335.1    
 DIJ69_33460   Streptomyces globisporus TFH56 AWL90724.1    
 C0216_15270   Streptomyces globosus LZH-48 AXE24642.1    
 C0216_05850   Streptomyces globosus LZH-48 AXE23039.1    
 AVL59_41890   Streptomyces griseochromogenes ATCC 14511 ANP55281.1    
 AVL59_33710   Streptomyces griseochromogenes ATCC 14511 ANP53859.1    
 AVL59_32560   Streptomyces griseochromogenes ATCC 14511 ANP56934.1    
 SGR_2125   Streptomyces griseus subsp. griseus NBRC 13350 BAG18954.1 B1W065  
 SGR_2445   Streptomyces griseus subsp. griseus NBRC 13350 BAG19274.1 B1W2B0  
 SGR_4702   Streptomyces griseus subsp. griseus NBRC 13350 BAG21531.1 B1VW20  
 SGR_6928   Streptomyces griseus subsp. griseus NBRC 13350 BAG23757.1 B1VPK7  
 endo-β-1,4-glucanase A (CelA1;Cel1;CMCASE I) 3.2.1.4 Streptomyces halstedii JM8 CAA78145.1 P33682  
 SHJG_1118   Streptomyces hygroscopicus subsp. jinggangensis 5008 AEY86395.1    
 SHJG_1119   Streptomyces hygroscopicus subsp. jinggangensis 5008 AEY86396.1    
 SHJG_7500   Streptomyces hygroscopicus subsp. jinggangensis 5008 AEY92767.1    
 SHJGH_0954   Streptomyces hygroscopicus subsp. jinggangensis TL01 AGF60620.1    
 SHJGH_0953   Streptomyces hygroscopicus subsp. jinggangensis TL01 AGF60619.1    
 SHJGH_7260   Streptomyces hygroscopicus subsp. jinggangensis TL01 AGF66922.1    
 SHL15_6377   Streptomyces hygroscopicus subsp. limoneus KCTC 1717 ALO97413.1    
 SHL15_8997   Streptomyces hygroscopicus subsp. limoneus KCTC 1717 ALO99917.1    
 SHL15_8996   Streptomyces hygroscopicus subsp. limoneus KCTC 1717 ALO99916.1    
 SHXM_07617   Streptomyces hygroscopicus XM201 AQW54154.1    
 SHXM_04454   Streptomyces hygroscopicus XM201 AQW50991.1    
 SHXM_04551   Streptomyces hygroscopicus XM201 AQW51088.1    
 SHXM_03184   Streptomyces hygroscopicus XM201 AQW49721.1    
 SHXM_00177   Streptomyces hygroscopicus XM201 AQW46714.1    
 SHXM_05208   Streptomyces hygroscopicus XM201 AQW51745.1    
 SHXM_07086   Streptomyces hygroscopicus XM201 AQW53623.1    
 ABB07_23745   Streptomyces incarnatus NRRL 8089 AKJ12938.1    
 SIRAN5392   Streptomyces iranensis CDR08745.1    
 SIRAN3158   Streptomyces iranensis CDR06248.1    
 SIRAN2693   Streptomyces iranensis CDR05759.1    
 SIRAN6118   Streptomyces iranensis CDR09509.1    
 SIRAN6225   Streptomyces iranensis CDR09619.1    
 SIRAN7699   Streptomyces iranensis CDR12571.1    
 D0C37_10485   Streptomyces koyangensis VK-A60T AXQ54989.1    
 D0C37_08670   Streptomyces koyangensis VK-A60T AXQ54664.1    
 D0C37_12820   Streptomyces koyangensis VK-A60T AXQ58946.1    
 SLA_5292   Streptomyces laurentii ATCC 31255 BAU86173.1    
 SLA_0108   Streptomyces laurentii ATCC 31255 BAU81063.1    
 Sle_12340   Streptomyces leeuwenhoekii C34 (= DSM 42122 = NRRL B-24963) CQR60696.1    
 Sle_09940   Streptomyces leeuwenhoekii C34 (= DSM 42122 = NRRL B-24963) CQR60457.1    
 SLCG_1630   Streptomyces lincolnensis LC-G AXG52785.1    
 SLCG_6955   Streptomyces lincolnensis LC-G AXG58110.1    
 SLCG_6723   Streptomyces lincolnensis LC-G AXG57878.1    
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