| Known Activities | endoglucanase (EC 3.2.1.4); cellobiohydrolase (EC 3.2.1.91) |
|---|---|
| Mechanism | Inverting |
| Catalytic Nucleophile/Base | Asp (experimental) |
| Catalytic Proton Donor | Asp (experimental) |
| Note | formerly known as cellulase family B. The cellobiohydrolases of this family are widely believed to act processively from the non-reducing ends of cellulose chains to generate cellobiose. |
| External resources | HOMSTRAD; InterPro; PFAM; PRINTS; PROSITE; |
| Statistics | GenBank accession (279); Uniprot accession (135); PDB accession (32); 3D entries (6); cryst (0) |
| Bacteria | ||||||
| Protein Name | EC# | Organism | GenBank | Uniprot | PDB/3D | |
| endoglucanase (CelA;Rv0062;MTV030.05) (Cel6) | 3.2.1.4 | Mycobacterium tuberculosis H37Rv | CAA16243.1 CAE55238.1 NP_214576.1 |
1UOZ[A] 1UP0[A] 1UP2[A] 1UP3[A] |
||
| endo-β-1,4-glucanase (E2;CelB;Tfu_1074) (Cel6A) | 3.2.1.4 | Thermobifida fusca YX | AAC06388.1 AAE59940.1 AAZ55112.1 |
P26222.2 Q47R05 |
1TML[A] 2BOD[X] 2BOE[X] 2BOF[X] 2BOG[X] |
|
| Eukaryota | ||||||
| Protein Name | EC# | Organism | GenBank | Uniprot | PDB/3D | |
| cellobiohydrolase (CcCel6C) (Cel6C) | 3.2.1.91 | Coprinopsis cinerea 5338 | BAH08704.1 | 3A64[A] 3A9A[A] 3A9B[A] 3ABX[A] |
||
| cellobiohydrolase (CBHII) (Cel6A) | 3.2.1.91 | Humicola insolens | Q9C1S9 | 1BVW[A] 1GZ1[A] 1OC5[A] 1OC6[A] 1OC7[A] 1OCB[A,B] 1OCJ[A] 1OCN[A] 2BVW[A] |
||
| endo-1,4-glucanase B (EG VI) (Cel6B) | 3.2.1.4 | Humicola insolens | Q7SIG5 | 1DYS[A] | ||
| cellobiohydrolase II (CBHII;Cbh2;CBH-II) (Cel6A) | 3.2.1.91 | Hypocrea jecorina QM9414 | AAA34210.1 AAA72922.1 AAE59936.1 AAG39980.1 AAR60513.1 CAR96032.1 CAR96033.1 CAV28333.1 |
P07987.1 Q9HEY8 |
1CB2[A,B] 1HGW[A,B] 1HGY[A,B] 1LG8 1LLX 1QJW[A,B] 1QK0[A,B] 1QK2[A,B] 3CBH[A] |
|