Glycoside Hydrolase Family 6

Activities in Familyendoglucanase (EC 3.2.1.4); cellobiohydrolase (EC 3.2.1.91)
Mechanism Inverting
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorAsp (experimental)
Noteformerly known as cellulase family B. The cellobiohydrolases of this family are widely believed to act processively from the non-reducing ends of cellulose chains to generate cellobiose.
External resourcesCAZypedia; HOMSTRAD; MEGAZYME; PRINTS; PROSITE;
Statistics GenBank accession (1243); Uniprot accession (242); PDB accession (50); 3D entries (12); cryst (1)
All (1154) Bacteria (967) Eukaryota (184) unclassified (3) Structure (12 - 1 cryst) Characterized (65)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 AA958_29910   Streptomyces sp. CNQ-509 AKH85741.1    
 AA958_06310   Streptomyces sp. CNQ-509 AKH81882.1    
 AA958_25040   Streptomyces sp. CNQ-509 AKH84931.1    
 AA958_00570 (fragment)   Streptomyces sp. CNQ-509 AKH80907.1    
 AA958_18545   Streptomyces sp. CNQ-509 AKH83873.1    
 SFR_2260   Streptomyces sp. FR-008 ALM38875.1    
 SFR_2761   Streptomyces sp. FR-008 ALM39376.1    
 SFR_1902   Streptomyces sp. FR-008 ALM38517.1    
 endo-1,4-glucanase A 3.2.1.4 Streptomyces sp. KSM-9 AAA26713.1
AAA26776.1
AAE59941.1
CAA43330.1
P13933  
 exoglucanase (CbhII) 3.2.1.91 Streptomyces sp. M23 BAB83928.1 Q8VLR1  
 CFP59_05026 (CelB)   Streptomyces sp. M56 AUA12873.1    
 CFP59_07059 (Cena_4)   Streptomyces sp. M56 AUA14877.1    
 CFP59_05679 (Cena_3)   Streptomyces sp. M56 AUA13516.1    
 CFP59_03130 (CasA)   Streptomyces sp. M56 AUA11020.1    
 CFP59_05775 (CbhA)   Streptomyces sp. M56 AUA13609.1    
 CFP59_09085 (Cela1)   Streptomyces sp. M56 AUA16893.1    
 CFP59_02601 (Cena_1)   Streptomyces sp. M56 AUA10502.1    
 STRMOE7_14780   Streptomyces sp. MOE7 ARH91356.1    
 F750_0531   Streptomyces sp. PAMC 26508 AGJ53042.1    
 F750_6288   Streptomyces sp. PAMC 26508 AGJ58714.1    
 QR97_19600   Streptomyces sp. PBH53 AKN71712.1    
 QR97_13990   Streptomyces sp. PBH53 AKN70775.1    
 QR97_19605   Streptomyces sp. PBH53 AKN71713.1    
 A4E84_33660   Streptomyces sp. S10(2016) AMW14007.1    
 A4E84_27615   Streptomyces sp. S10(2016) AMW12928.1    
 A4E84_07140   Streptomyces sp. S10(2016) AMW09289.1    
 A4E84_15000   Streptomyces sp. S10(2016) AMW10699.1    
 A4E84_03405   Streptomyces sp. S10(2016) AMW08638.1    
 A6E92_08400   Streptomyces sp. S8 ARI52196.1    
 A6E92_20900   Streptomyces sp. S8 ARI54362.1    
 A6E92_00820   Streptomyces sp. S8 ARI50837.1    
 A6E92_09975   Streptomyces sp. S8 ARI52474.1    
 A8713_26655   Streptomyces sp. SAT1 ANH94322.1    
 A8713_11380   Streptomyces sp. SAT1 ANH91701.1    
 CAG99_06960   Streptomyces sp. SCSIO 03032 ARQ68630.1    
 CAG99_05630   Streptomyces sp. SCSIO 03032 ARQ68398.1    
 CAG99_05115   Streptomyces sp. SCSIO 03032 ARQ68307.1    
 CAG99_03365   Streptomyces sp. SCSIO 03032 ARQ68000.1    
 CAG99_06935   Streptomyces sp. SCSIO 03032 ARQ68625.1    
 exo-cellulase (SACTE_0237)   Streptomyces sp. SirexAA-E AEN08184.1    
 SAMN05216371_0488   Streptomyces sp. TLI_053 SDS72578.1    
 SAMN05216371_5082   Streptomyces sp. TLI_053 SDT76023.1    
 BSL84_23150   Streptomyces sp. TN58 APU42241.1    
 TK78_09300   Streptomyces sp. Tue 6075 Tue6075 APS19134.1    
 TK78_22555   Streptomyces sp. Tue 6075 Tue6075 APS21393.1    
 TK78_29895   Streptomyces sp. Tue 6075 Tue6075 APS22683.1    
 SVEN_6713   Streptomyces venezuelae ATCC 10712 CCA59999.1    
 SVEN_6595 (fragment)   Streptomyces venezuelae ATCC 10712 CCA59881.1    
 SVEN_6712   Streptomyces venezuelae ATCC 10712 CCA59998.1    
 SVEN_5064+SVEN_5063   Streptomyces venezuelae ATCC 10712 CCA58349.1
CCA58350.1
   
 BN2537_3231   Streptomyces venezuelae ATCC 15439 CUM37133.1    
 BN2537_10939   Streptomyces venezuelae ATCC 15439 CUM40987.1    
 BN2537_5745   Streptomyces venezuelae ATCC 15439 CUM38390.1    
 BN2537_15925   Streptomyces venezuelae ATCC 15439 CUM43480.1    
 BN2537_15927   Streptomyces venezuelae ATCC 15439 CUM43481.1    
 AQF52_5510   Streptomyces venezuelae ATCC 15439 ALO11104.1    
 AQF52_0673   Streptomyces venezuelae ATCC 15439 ALO06270.1    
 AQF52_6683   Streptomyces venezuelae ATCC 15439 ALO12276.1    
 AQF52_3044   Streptomyces venezuelae ATCC 15439 ALO08638.1    
 AQF52_0674   Streptomyces venezuelae ATCC 15439 ALO06271.1    
 SVTN_36755   Streptomyces vietnamensis GIM4.0001 AJF69026.1    
 SVTN_32835   Streptomyces vietnamensis GIM4.0001 AJF68425.1    
 SVTN_36760   Streptomyces vietnamensis GIM4.0001 AJF69027.1    
 B1H20_00285   Streptomyces violaceoruber S21 ARF59988.1    
 B1H20_25425   Streptomyces violaceoruber S21 ARF64351.1    
 Strvi_1875   Streptomyces violaceusniger Tu 4113 AEM81610.1    
 Strvi_6722   Streptomyces violaceusniger Tu 4113 AEM86102.1    
 Strvi_8132   Streptomyces violaceusniger Tu 4113 AEM87455.1    
 Strvi_8233   Streptomyces violaceusniger Tu 4113 AEM87553.1    
 Strvi_8932   Streptomyces violaceusniger Tu 4113 AEM88233.1    
 Strvi_2397   Streptomyces violaceusniger Tu 4113 AEM82121.1    
 SXIM_43350   Streptomyces xiamenensis 318 AKG45719.1    
 SXIM_39640   Streptomyces xiamenensis 318 AKG45348.1    
 SXIM_39610   Streptomyces xiamenensis 318 AKG45345.1    
 SXIM_47450   Streptomyces xiamenensis 318 AKG46129.1    
 cellobiohydrolase (Cbh) (fragment)   Streptomyces xylophagus KX6 ADK32332.1 E2GJC5  
 Sros_3907   Streptosporangium roseum DSM 43021 ACZ86824.1 D2AUW2  
 Sros_6407   Streptosporangium roseum DSM 43021 ACZ89121.1 D2B0B5  
 Sros_6890   Streptosporangium roseum DSM 43021 ACZ89593.1 D2B768  
 TERTU_2895 (CelA)   Teredinibacter turnerae T7901 ACR12145.1 C5BNA9  
 TERTU_3996   Teredinibacter turnerae T7901 ACR14000.1 C5BTS3  
 TERTU_2898   Teredinibacter turnerae T7901 ACR12723.1 C5BNB1  
 bifunctional β-1,4-endoglucanase / cellobiohydrolase (CelAB) 3.2.1.4
3.2.1.91
Teredinibacter turnerae T7901 ABS72374.1 A9Q634  
 RPIT_07825   Tessaracoccus flavus RP1T AQP44725.1    
 BKM78_08455   Tessaracoccus sp. T2.5-30 AQX15944.1    
 cellulase (Cel6A)   Thermoactinospora rubra YIM 77501 ALR99813.1    
 endo-1,4-beta glucanase E2   Thermobifida alba AHK119 BBA57843.1    
 cellobiohydrolase 6B / exoglucanase (E3;Ex;Tfu_0620) (Cel6B) 3.2.1.91 Thermobifida fusca YX AAA62211.1
AAF75786.1
AAZ54658.1
ABH87632.1
Q47SA9
Q60029
Q9KH72
4AVN[A]
4AVO[A]
4B4F[A,B]
4B4H[A,B]
 endo-β-1,4-glucanase (E2;CelB;Tfu_1074) (Cel6A) 3.2.1.4 Thermobifida fusca YX AAC06388.1
AAE59940.1
AAZ55112.1
P26222
Q47R05
1TML[A]
2BOD[X]
2BOE[X]
2BOF[X]
2BOG[X]
3RU8[X]
 endoglucanase (ThCel6A) (alkali-stable) (Cel6A) 3.2.1.4 Thermobifida halotolerans YIM 90462T AHN09982.1    
 endo-β-1,4-glucanase A (CelA) 3.2.1.4 Thermobispora bispora / Microbispora bispora   P26414  
 Tbis_2830   Thermobispora bispora DSM 43833 ADG89529.1 D6Y6N8  
 Tbis_2656   Thermobispora bispora DSM 43833 ADG89357.1 D6Y5G2  
 Tcur_1738   Thermomonospora curvata DSM 43183 ACY97312.1 D1AC46  
 glycosyl hydrolase family 6 domain-containing protein, partial (fragment)   uncultured Alteromonadaceae bacterium AIF91561.1    
 exo-glucanase (Exo) (fragment)   uncultured bacterium AEI54553.1    
 cellulase (Cel6H) (partial) (Cel6H) 3.2.1.4 uncultured bacterium AEK21789.1    
 cellulase (Lc-CelB) 3.2.1.4 uncultured bacterium AHL27895.1    
 cellulase (Lc-CelJ) 3.2.1.4 uncultured bacterium AHL27903.1    
 chitinase   uncultured bacterium AZ_40 AKA59481.1    
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