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Glycoside Hydrolase Family 5

Activities in Family[retaining] arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-);
β-1,3-mannanase (EC 3.2.1.-);
β-rutinosidase /α-L-rhamnose-(1,6)-β-D-glucosidase (EC 3.2.1.-);
Glucomannan-specific endo-β-1,4-glucanase (EC 3.2.1.-);
Mannan exo-β-1,4-mannosidase (EC 3.2.1.-);
Steryl β-glucosidase (EC 3.2.1.104);
Endoglycosylceramidase (EC 3.2.1.123);
Chitosanase (EC 3.2.1.132);
β-D-galactofuranosidase (EC 3.2.1.146);
β-primeverosidase (EC 3.2.1.149);
Oligoxyloglucan reducing-end-specific cellobiohydrolase (EC 3.2.1.150);
Xyloglucan-specific endo-β-1,4-glucanase / endo-xyloglucanase (EC 3.2.1.151);
Endo-β-1,6-galactanase (EC 3.2.1.164);
Hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168);
β-glucosidase (EC 3.2.1.21);
β-galactosidase (EC 3.2.1.23);
β-mannosidase (EC 3.2.1.25);
Xylan β-1,4-xylosidase (EC 3.2.1.37);
Endo-β-1,3-glucanase / laminarinase (EC 3.2.1.39);
Endo-β-1,4-glucanase (EC 3.2.1.4);
β-glucosylceramidase (EC 3.2.1.45);
β-galactosylceramidase (EC 3.2.1.46);
β-N-acetylhexosaminidase (EC 3.2.1.52);
α-L-arabinofuranosidase (EC 3.2.1.55);
Exo-β-1,3-glucanase (EC 3.2.1.58);
Endo-β-1,3(4)-glucanase / lichenase-laminarinase (EC 3.2.1.6);
Lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73);
Exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74);
Endo-β-1,6-glucanase (EC 3.2.1.75);
Endo-β-1,4-mannanase (EC 3.2.1.78);
Endo-β-1,4-xylanase (EC 3.2.1.8);
Cellobiohydrolase (EC 3.2.1.91);
Mechanism Retaining e
ClanGH-A
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (31227); Uniprot accession (673); PDB accession (296); 3D entries (110); cryst (0)
Summary
Download GH5 (44486) Taxonomic display Structure (110) Characterized (624)
| 1 | ... | 184 | 185 | 186 | 187 | 188 | 189 | 190 | 191 | 192 | ... | 198 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 1643   Wallemia ichthyophaga EXF-994 (Walic1)       9
 2220   Wallemia ichthyophaga EXF-994 (Walic1)       12
 2395   Wallemia ichthyophaga EXF-994 (Walic1)      
 176   Wallemia ichthyophaga EXF-994 (Walic1)       12
 520   Wallemia ichthyophaga EXF-994 (Walic1)       9
 3913   Wallemia ichthyophaga EXF-994 (Walic1)       9
 3291   Wallemia ichthyophaga EXF-994 (Walic1)       50
 3193   Wallemia ichthyophaga EXF-994 (Walic1)       50
 1404   Wallemia ichthyophaga EXF-994 (Walic1)       9
 43243   Wallemia sebi v1 (Walse1)       12
 50317   Wallemia sebi v1 (Walse1)       9
 36342   Wallemia sebi v1 (Walse1)       12
 32390   Wallemia sebi v1 (Walse1)       9
 69973   Wallemia sebi v1 (Walse1)       9
 34039   Wallemia sebi v1 (Walse1)       9
 61596   Wallemia sebi v1 (Walse1)       50
 59673   Wallemia sebi v1 (Walse1)      
 60653   Wallemia sebi v1 (Walse1)       50
 470014   Westerdykella ornata CBS 379.55 (Wesor1)      
 489071   Westerdykella ornata CBS 379.55 (Wesor1)       12
 60640   Westerdykella ornata CBS 379.55 (Wesor1)       4
 461577   Westerdykella ornata CBS 379.55 (Wesor1)       7
 372634   Westerdykella ornata CBS 379.55 (Wesor1)       9
 81617   Westerdykella ornata CBS 379.55 (Wesor1)       5
 413313   Westerdykella ornata CBS 379.55 (Wesor1)       16
 494640   Westerdykella ornata CBS 379.55 (Wesor1)       7
 381774   Westerdykella ornata CBS 379.55 (Wesor1)       11
 419002   Westerdykella ornata CBS 379.55 (Wesor1)       16
 412299   Westerdykella ornata CBS 379.55 (Wesor1)       5
 435267   Westerdykella ornata CBS 379.55 (Wesor1)       9
 500124   Westerdykella ornata CBS 379.55 (Wesor1)       9
 540592   Whalleya microplaca YMJ1829 v1.0 (Whamic1)       12
 84587   Whalleya microplaca YMJ1829 v1.0 (Whamic1)       7
 450757   Whalleya microplaca YMJ1829 v1.0 (Whamic1)      
 529595   Whalleya microplaca YMJ1829 v1.0 (Whamic1)       24
 519130   Whalleya microplaca YMJ1829 v1.0 (Whamic1)       15
 357762   Whalleya microplaca YMJ1829 v1.0 (Whamic1)       15
 546752   Whalleya microplaca YMJ1829 v1.0 (Whamic1)       5
 552318   Whalleya microplaca YMJ1829 v1.0 (Whamic1)       7
 21809   Whalleya microplaca YMJ1829 v1.0 (Whamic1)       11
 517725   Whalleya microplaca YMJ1829 v1.0 (Whamic1)       16
 526628   Whalleya microplaca YMJ1829 v1.0 (Whamic1)       16
 499432   Whalleya microplaca YMJ1829 v1.0 (Whamic1)       4
 549368   Whalleya microplaca YMJ1829 v1.0 (Whamic1)       9
 552636   Whalleya microplaca YMJ1829 v1.0 (Whamic1)       15
 578148   Whalleya microplaca YMJ1829 v1.0 (Whamic1)       16
 388285   Whalleya microplaca YMJ1829 v1.0 (Whamic1)       5
 360930   Whalleya microplaca YMJ1829 v1.0 (Whamic1)       5
 exo-β-1,3-glucanase   Wickerhamomyces anomalus ARX76274.1     9
 exo-β-1,3-glucanase (Exg1;PaEXG1;WaEXG1)   Wickerhamomyces anomalus CAA05243.1     9
 exo-1,3-β-glucanase (Exg2;PaEXG2)   Wickerhamomyces anomalus AGC67022.1     9
 exo-β-1,3-glucanase (Exg1)   Wickerhamomyces anomalus AS F17.12 CDF77670.1     9
 exo-β-1,3-glucanase (Exg2)   Wickerhamomyces anomalus AS F17.12 CDF77671.1     9
 exo-β-1,3-glucanase (Exg2)   Wickerhamomyces anomalus AS1 CDH93665.1     9
 exo-β-1,3-glucanase (Exg2;WaEXG2)   Wickerhamomyces anomalus BCA15 AFK33204.1     9
 exo-β-1,3-glucanase (Exg1;WaEXG1) (fragment)   Wickerhamomyces anomalus BCA15 AFK33201.1     9
 exo-β-1,3-glucanase (Exg1;WaEXG1)   Wickerhamomyces anomalus BCU24 AFK33202.1     9
 exo-β-1,3-glucanase (Exg2;WaEXG2)   Wickerhamomyces anomalus BCU24 AFK33205.1     9
 exo-β-1,3-glucanase (Exg1;WaEXG1)   Wickerhamomyces anomalus BS91 AFK33200.1     9
 exo-β-1,3-glucanase (Exg2;WaEXG2)   Wickerhamomyces anomalus BS91 AFK33203.1     9
 exo-1,3-β-glucanase, partial (Exg2) (fragment)   Wickerhamomyces anomalus Cf20 QKG01944.1     9
 exo-1,3-β-glucanase, partial (Exg1) (fragment)   Wickerhamomyces anomalus Cf20 QKG01943.1     9
 exo-β-1,3-glucanase (Exg2;PaEXG2;WaEXG2) 3.2.1.58 Wickerhamomyces anomalus K / NCYC 432 CAA11018.1 O93983   9
 WAN_9541   Wickerhamomyces anomalus NRRL Y-366 AEZ66638.1     9
 WAN_6658   Wickerhamomyces anomalus NRRL Y-366 AEZ66635.1     9
 WAN_362   Wickerhamomyces anomalus NRRL Y-366 AEZ66636.1     9
 WAN_2708   Wickerhamomyces anomalus NRRL Y-366 AEZ66637.1     9
 WAN_5696   Wickerhamomyces anomalus NRRL Y-366 AEZ66639.1     49
 WAN_7786   Wickerhamomyces anomalus NRRL Y-366 AEZ66642.1     49
 WAN_7517   Wickerhamomyces anomalus NRRL Y-366 AEZ66640.1     12
 WAN_7540   Wickerhamomyces anomalus NRRL Y-366 AEZ66641.1     12
 exo-1,3-β-glucanase (Exg1;PaEXG1)   Wickerhamomyces anomalus WRL-076 AGC67021.1     9
 exo-β-1,3-glucanase (Exg2;PaEXG2;WaEXG2)   Wickerhamomyces anomalus YF07b ABK40520.1     9
 542060   Wilcoxina mikolae CBS 423.85 (Wilmi1)       12
 561075   Wilcoxina mikolae CBS 423.85 (Wilmi1)       15
 552262   Wilcoxina mikolae CBS 423.85 (Wilmi1)       49
 562907   Wilcoxina mikolae CBS 423.85 (Wilmi1)       9
 542612   Wilcoxina mikolae CBS 423.85 (Wilmi1)       9
 656299   Wilcoxina mikolae CBS 423.85 (Wilmi1)       12
 591758   Wilcoxina mikolae CBS 423.85 (Wilmi1)       22
 exo-β-1,3-glucanase (Exg1;WsExg1) 3.2.1.58 Williopsis saturnus WC91-2 ACP74152.2
ACP74152.1		 C3VMY4   9
 147868   Wolfiporia cocos MD-104 SS10 (Wolco1)       7
 141870   Wolfiporia cocos MD-104 SS10 (Wolco1)       5
 112799   Wolfiporia cocos MD-104 SS10 (Wolco1)       5
 135575   Wolfiporia cocos MD-104 SS10 (Wolco1)       9
 130689   Wolfiporia cocos MD-104 SS10 (Wolco1)       50
 136068   Wolfiporia cocos MD-104 SS10 (Wolco1)       9
 136320   Wolfiporia cocos MD-104 SS10 (Wolco1)       12
 137547   Wolfiporia cocos MD-104 SS10 (Wolco1)       9
 72878   Wolfiporia cocos MD-104 SS10 (Wolco1)       9
 26252   Wolfiporia cocos MD-104 SS10 (Wolco1)       7
 26848   Wolfiporia cocos MD-104 SS10 (Wolco1)       15
 139561   Wolfiporia cocos MD-104 SS10 (Wolco1)       22
 106510   Wolfiporia cocos MD-104 SS10 (Wolco1)       22
 79891   Wolfiporia cocos MD-104 SS10 (Wolco1)       50
 140075   Wolfiporia cocos MD-104 SS10 (Wolco1)       9
 140649   Wolfiporia cocos MD-104 SS10 (Wolco1)       12
 129676   Wolfiporia cocos MD-104 SS10 (Wolco1)       31
 144596   Wolfiporia cocos MD-104 SS10 (Wolco1)       31
 glycoside hydrolase   Xanthophyllomyces dendrorhous CDZ97258.1     12
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