| Activities in Family | [retaining] arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); β-1,3-mannanase (EC 3.2.1.-); β-rutinosidase /α-L-rhamnose-(1,6)-β-D-glucosidase (EC 3.2.1.-); Glucomannan-specific endo-β-1,4-glucanase (EC 3.2.1.-); Mannan exo-β-1,4-mannosidase (EC 3.2.1.-); Steryl β-glucosidase (EC 3.2.1.104); Endoglycosylceramidase (EC 3.2.1.123); Chitosanase (EC 3.2.1.132); β-D-galactofuranosidase (EC 3.2.1.146); β-primeverosidase (EC 3.2.1.149); Oligoxyloglucan reducing-end-specific cellobiohydrolase (EC 3.2.1.150); Xyloglucan-specific endo-β-1,4-glucanase / endo-xyloglucanase (EC 3.2.1.151); Endo-β-1,6-galactanase (EC 3.2.1.164); Hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-glucosidase (EC 3.2.1.21); β-galactosidase (EC 3.2.1.23); β-mannosidase (EC 3.2.1.25); Xylan β-1,4-xylosidase (EC 3.2.1.37); Endo-β-1,3-glucanase / laminarinase (EC 3.2.1.39); Endo-β-1,4-glucanase (EC 3.2.1.4); β-glucosylceramidase (EC 3.2.1.45); β-galactosylceramidase (EC 3.2.1.46); β-N-acetylhexosaminidase (EC 3.2.1.52); α-L-arabinofuranosidase (EC 3.2.1.55); Exo-β-1,3-glucanase (EC 3.2.1.58); Endo-β-1,3(4)-glucanase / lichenase-laminarinase (EC 3.2.1.6); Lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73); Exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); Endo-β-1,6-glucanase (EC 3.2.1.75); Endo-β-1,4-mannanase (EC 3.2.1.78); Endo-β-1,4-xylanase (EC 3.2.1.8); Cellobiohydrolase (EC 3.2.1.91); |
|---|---|
| Mechanism | Retaining e |
| Clan | GH-A |
| 3D Structure Status | ( β / α ) 8 barrel |
| Catalytic Nucleophile/Base | Glu (experimental) |
| Catalytic Proton Donor | Glu (experimental) |
| Note | Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189). |
| External resources | CAZypedia; HOMSTRAD; PROSITE; |
| Commercial Enzyme Provider(s) | MEGAZYME; NZYTech; PROZOMIX; |
| Statistics | GenBank accession (31227); Uniprot accession (673); PDB accession (296); 3D entries (110); cryst (0) |
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| Bacteria | |||||||
| Protein Name | EC# | Organism | GenBank | Uniprot | PDB/3D | Subf | |
| endo-1,4-β-glucanase, partial (EgL) (fragment) | Ralstonia solanacearum NIM2T1 | ARS25022.1 | 5 | ||||
| endo-1,4-β-glucanase, partial (EgL) (fragment) | Ralstonia solanacearum NIM3T1 | ARS25017.1 | 5 | ||||
| endoglucanase (fragment) | Ralstonia solanacearum NPB16F | ABO86749.1 | 5 | ||||
| endoglucanase (fragment) | Ralstonia solanacearum NPB4G | ABO86757.1 | 5 | ||||
| endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum NPEB1 | BBD82081.1 | 5 | ||||
| endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum NPEB2 | BBD82082.1 | 5 | ||||
| endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum NPEB3 | BBD82083.1 | 5 | ||||
| endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum NPEB4 | BBD82084.1 | 5 | ||||
| endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum NPEB5 | BBD82085.1 | 5 | ||||
| endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum NPEB6 | BBD82086.1 | 5 | ||||
| endoglucanase, partial (fragment) | Ralstonia solanacearum NS-KP1 | AHC71996.1 | 5 | ||||
| endoglucanase, partial (fragment) | Ralstonia solanacearum NS-N1 | AHN13873.1 | 5 | ||||
| endoglucanase, partial (fragment) | Ralstonia solanacearum NS-PD1 | AHN13874.1 | 5 | ||||
| endoglucanase, partial (fragment) | Ralstonia solanacearum NS-PD2 | AHN13875.1 | 5 | ||||
| endoglucanase, partial (fragment) | Ralstonia solanacearum NS-S1 | AHC71994.1 | 5 | ||||
| endoglucanase, partial (fragment) | Ralstonia solanacearum NS-S2 | AHC71995.1 | 5 | ||||
| endoglucanase precursor, partial (fragment) | Ralstonia solanacearum Nt-Nx-04-1 | AGJ52309.1 | 5 | ||||
| endoglucanase precursor, partial (fragment) | Ralstonia solanacearum Nt-Nx-04-4 | AGJ52310.1 | 5 | ||||
| endoglucanase precursor, partial (fragment) | Ralstonia solanacearum Nt-Nx-04-5 | AGJ52311.1 | 5 | ||||
| endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum NTA2 | BBD82078.1 | 5 | ||||
| endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum NTA4 | BBD82079.1 | 5 | ||||
| endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum NTA6 | BBD82080.1 | 5 | ||||
| endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum NTC1 | BBD82087.1 | 5 | ||||
| endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum NTC2 | BBD82088.1 | 5 | ||||
| endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum NTC4 | BBD82089.1 | 5 | ||||
| endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum NTC5 | BBD82090.1 | 5 | ||||
| endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum NTC6 | BBD81918.1 | 5 | ||||
| endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum NTC7 | BBD82091.1 | 5 | ||||
| endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum NTC8 | BBD82092.1 | 5 | ||||
| endo-1,4-β-glucanase, partial (EgL) (fragment) | Ralstonia solanacearum O1 | ARS24952.1 | 5 | ||||
| endoglucanase (Egl) (fragment) | Ralstonia solanacearum O2 | ACT20649.1 | 5 | ||||
| endoglucanase (Egl) (fragment) | Ralstonia solanacearum O3 | ACT20605.1 | 5 | ||||
| RSOE_00550 | Ralstonia solanacearum OE1-1 | APC65920.2 | 5 | ||||
| endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum orp-11 | ALJ03564.1 | 5 | ||||
| endo-1,4-β-glucanase, partial (EgL) (fragment) | Ralstonia solanacearum OUAT1 | ARS25024.1 | 5 | ||||
| endoglucanase precursor, partial (fragment) | Ralstonia solanacearum OzT67 | ASJ82144.1 | 5 | ||||
| endoglucanase precursor, partial (EgL) (fragment) | Ralstonia solanacearum P | AVH78212.1 | 5 | ||||
| endo-1,4-β-glucanase, partial (EgL) (fragment) | Ralstonia solanacearum P1 | ARS24901.1 | 5 | ||||
| endoglucanase (fragment) | Ralstonia solanacearum P3-332 | AAS46786.1 | 5 | ||||
| endo-1,4-β-glucanase, partial (EgL) (fragment) | Ralstonia solanacearum P6 | ARS24913.1 | 5 | ||||
| endoglucanase (fragment) | Ralstonia solanacearum P67 | AAS46780.1 | 5 | ||||
| endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum P816 | AVX33659.1 | 5 | ||||
| endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum P822 | AVX33660.1 | 5 | ||||
| endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum P824 | AVX33661.1 | 5 | ||||
| RSP824_18400 | Ralstonia solanacearum P824 | AYA48453.1 | 5 | ||||
| endo-1,4-β-glucanase, partial (EgL) (fragment) | Ralstonia solanacearum PATT3 | ARS25025.1 | 5 | ||||
| endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum PD 1446 | AGT98978.1 | 5 | ||||
| endoglucanase (EgL) (fragment) | Ralstonia solanacearum PD1100 | ABG46742.1 | 5 | ||||
| endoglucanase (EgL) (fragment) | Ralstonia solanacearum PD1610 | ABG46754.1 | 5 | ||||
| endoglucanase (EgL) (fragment) | Ralstonia solanacearum PD1939 | ABG46741.1 | 5 | ||||
| endoglucanase (EgL) (fragment) | Ralstonia solanacearum PD441 | ABG46753.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum PeaFJ1 | AUW56656.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum PeaHuB4 | AUT32385.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum PepFJ1 | AUW56657.1 | 5 | ||||
| endo-1,4-β-glucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pepino 7 | ARS24984.1 | 5 | ||||
| endoglucanase, partial (fragment) | Ralstonia solanacearum Phg-K1 | AHC72000.1 | 5 | ||||
| endoglucanase, partial (fragment) | Ralstonia solanacearum Phg-K2 | AHC72001.1 | 5 | ||||
| endoglucanase, partial (fragment) | Ralstonia solanacearum Phg-L1 | AHC72002.1 | 5 | ||||
| endoglucanase, partial (fragment) | Ralstonia solanacearum Phg-L2 | AHN13879.1 | 5 | ||||
| endoglucanase, partial (fragment) | Ralstonia solanacearum Phg-P1 | AHN13880.1 | 5 | ||||
| endoglucanase, partial (fragment) | Ralstonia solanacearum Phg-P2 | AHN13881.1 | 5 | ||||
| RUN215_v1_950005 (EgL) | Ralstonia solanacearum Phyl III-seqv23 | CUV56696.1 | 5 | ||||
| TO10_v1_770012 (EgL) | Ralstonia solanacearum Phyl III-seqv23 | CUV46989.1 | 5 | ||||
| RUN39_v1_1440006 (EgL) | Ralstonia solanacearum Phyl III-seqv23 | CUV15470.1 | 5 | ||||
| RD1301_v1_3990006 (EgL) | Ralstonia solanacearum Phyl III-seqv23 | CUV63830.1 | 5 | ||||
| PSS4_v1_480011 (EgL) | Ralstonia solanacearum Phyl III-seqv23 | CUV18106.1 | 5 | ||||
| RUN1985_v1_700005 (EgL) | Ralstonia solanacearum Phyl III-seqv23 | CUV30711.1 | 5 | ||||
| TO10_v1_2920001 (fragment) | Ralstonia solanacearum Phyl III-seqv23 | CUV48252.1 | 5 | ||||
| endoglucanase, partial (fragment) | Ralstonia solanacearum PLU-1 | AQY45780.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn01 | AWX63134.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn02 | AWX63135.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn03 | AWX63136.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn04 | AWX63137.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn05 | AWX63138.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn06 | AWX63139.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn07 | AWX63140.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn08 | AWX63141.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn10 | AWX63142.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn11 | AWX63143.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn12 | AWX63144.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn13 | AWX63145.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn14 | AWX63146.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn15 | AWX63147.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn16 | AWX63148.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn17 | AWX63149.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn18 | AWX63150.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn19 | AWX63151.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn20 | AWX63152.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn22 | AWX63153.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn23 | AWX63154.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn24 | AWX63155.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn25 | AWX63156.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn26 | AWX63157.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn27 | AWX63158.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn28 | AWX63159.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn29 | AWX63160.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn30 | AWX63161.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn31 | AWX63162.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn32 | AWX63163.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum Pn33 | AWX63164.1 | 5 | ||||
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