| Activities in Family | [retaining] arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); β-1,3-mannanase (EC 3.2.1.-); β-rutinosidase /α-L-rhamnose-(1,6)-β-D-glucosidase (EC 3.2.1.-); Glucomannan-specific endo-β-1,4-glucanase (EC 3.2.1.-); Mannan exo-β-1,4-mannosidase (EC 3.2.1.-); Steryl β-glucosidase (EC 3.2.1.104); Endoglycosylceramidase (EC 3.2.1.123); Chitosanase (EC 3.2.1.132); β-D-galactofuranosidase (EC 3.2.1.146); β-primeverosidase (EC 3.2.1.149); Oligoxyloglucan reducing-end-specific cellobiohydrolase (EC 3.2.1.150); Xyloglucan-specific endo-β-1,4-glucanase / endo-xyloglucanase (EC 3.2.1.151); Endo-β-1,6-galactanase (EC 3.2.1.164); Hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-glucosidase (EC 3.2.1.21); β-galactosidase (EC 3.2.1.23); β-mannosidase (EC 3.2.1.25); Xylan β-1,4-xylosidase (EC 3.2.1.37); Endo-β-1,3-glucanase / laminarinase (EC 3.2.1.39); Endo-β-1,4-glucanase (EC 3.2.1.4); β-glucosylceramidase (EC 3.2.1.45); β-galactosylceramidase (EC 3.2.1.46); β-N-acetylhexosaminidase (EC 3.2.1.52); α-L-arabinofuranosidase (EC 3.2.1.55); Exo-β-1,3-glucanase (EC 3.2.1.58); Endo-β-1,3(4)-glucanase / lichenase-laminarinase (EC 3.2.1.6); Lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73); Exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); Endo-β-1,6-glucanase (EC 3.2.1.75); Endo-β-1,4-mannanase (EC 3.2.1.78); Endo-β-1,4-xylanase (EC 3.2.1.8); Cellobiohydrolase (EC 3.2.1.91); |
|---|---|
| Mechanism | Retaining e |
| Clan | GH-A |
| 3D Structure Status | ( β / α ) 8 barrel |
| Catalytic Nucleophile/Base | Glu (experimental) |
| Catalytic Proton Donor | Glu (experimental) |
| Note | Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189). |
| External resources | CAZypedia; HOMSTRAD; PROSITE; |
| Commercial Enzyme Provider(s) | MEGAZYME; NZYTech; PROZOMIX; |
| Statistics | GenBank accession (31227); Uniprot accession (673); PDB accession (296); 3D entries (110); cryst (0) |
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| Bacteria | |||||||
| Protein Name | EC# | Organism | GenBank | Uniprot | PDB/3D | Subf | |
| endoglucanase, partial (fragment) | Ralstonia solanacearum HP15-2 | BBJ06313.1 | 5 | ||||
| endoglucanase, partial (fragment) | Ralstonia solanacearum HP17-1 | BBJ06316.1 | 5 | ||||
| endoglucanase, partial (fragment) | Ralstonia solanacearum HP17-2 | BBJ06317.1 | 5 | ||||
| endoglucanase, partial (fragment) | Ralstonia solanacearum HP2-1 | BBJ06307.1 | 5 | ||||
| endoglucanase, partial (fragment) | Ralstonia solanacearum HP2-2 | BBJ06308.1 | 5 | ||||
| endoglucanase, partial (fragment) | Ralstonia solanacearum HP4-2 | BBJ06311.1 | 5 | ||||
| endoglucanase, partial (fragment) | Ralstonia solanacearum HP7-1 | BBJ06314.1 | 5 | ||||
| endoglucanase, partial (fragment) | Ralstonia solanacearum HP7-2 | BBJ06315.1 | 5 | ||||
| endo-1,4-β-glucanase, partial (EgL) (fragment) | Ralstonia solanacearum HRA1 | ARS24964.1 | 5 | ||||
| endo-1,4-β-glucanase, partial (EgL) (fragment) | Ralstonia solanacearum HRGP1 | ARS24963.1 | 5 | ||||
| endoglucanase precursor, partial (EgL) (fragment) | Ralstonia solanacearum Hz03310s1 | ALK82510.1 | 5 | ||||
| endoglucanase precursor, partial (EgL) (fragment) | Ralstonia solanacearum Hz651s1 | ALK82511.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU001 | AUT32296.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU0012 | AUT32307.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU0014 | AUT32309.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU0015 | AUT32310.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU0016 | AUT32311.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU0018 | AUT32313.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU002 | AUT32297.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU003 | AUT32298.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU004 | AUT32299.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU005 | AUT32300.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU006 | AUT32301.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU007 | AUT32302.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU008 | AUT32303.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU009 | AUT32304.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU010 | AUT32305.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU011 | AUT32306.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU013 | AUT32308.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU017 | AUT32312.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU019 | AUT32314.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU020 | AUT32315.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU021 | AUT32316.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU022 | AUT32317.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU023 | AUT32318.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU024 | AUT32319.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU025 | AUT32320.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU026 | AUT32321.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU027 | AUT32322.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU028 | AUT32323.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU031 | AUT32324.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU032 | AUT32325.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU033 | AUT32326.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU034 | AUT32327.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU035 | AUT32328.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU036 | AUT32329.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU037 | AUT32330.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU038 | AUT32331.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU039 | AUT32332.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU040 | AUT32333.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU041 | AUT32334.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU042 | AUT32335.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU043 | AUT32336.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU044 | AUT32337.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU045 | AUT32338.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU046 | AUT32339.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU047 | AUT32340.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU048 | AUT32341.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU049 | AUT32342.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU050 | AUT32343.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU051 | AUT32344.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU052 | AUT32345.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU053 | AUT32346.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU054 | AUT32347.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU055 | AUT32348.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU056 | AUT32349.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU057 | AUT32350.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU058 | AUT32351.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU059 | AUT32352.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU060 | AUT32353.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU061 | AUT32354.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU062 | AUT32355.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU063 | AUT32356.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU064 | AUT32357.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU065 | AUT32358.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU066 | AUT32359.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU067 | AUT32360.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU068 | AUT32361.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU069 | AUT32362.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU070 | AUT32363.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU071 | AUT32364.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU072 | AUT32365.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU073 | AUT32366.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU074 | AUT32367.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU075 | AUT32368.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU076 | AUT32369.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU077 | AUT32370.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU079 | AUT32371.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU080 | AUT32372.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU081 | AUT32373.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU082 | AUT32374.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU083 | AUT32375.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU084 | AUT32376.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU085 | AUT32377.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU086 | AUT32378.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU087 | AUT32379.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU088 | AUT32380.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU090 | AUT32381.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU093 | AUT32382.1 | 5 | ||||
| β-1,4-endoglucanase, partial (EgL) (fragment) | Ralstonia solanacearum HZAU094 | AUT32383.1 | 5 | ||||
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