Glycoside Hydrolase Family 5 / Subf 4

Activities in Sub FamilyGlucomannan-specific endo-β-1,4-glucanase (EC 3.2.1.-);
Oligoxyloglucan reducing-end-specific cellobiohydrolase (EC 3.2.1.150);
Xyloglucan-specific endo-β-1,4-glucanase / endo-xyloglucanase (EC 3.2.1.151);
Endo-β-1,4-glucanase (EC 3.2.1.4);
Endo-β-1,3(4)-glucanase / lichenase-laminarinase (EC 3.2.1.6);
Lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73);
Endo-β-1,4-mannanase (EC 3.2.1.78);
Endo-β-1,4-xylanase (EC 3.2.1.8);
Mechanism Retaining e
ClanGH-A
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (428); Uniprot accession (139); PDB accession (56); 3D entries (28); cryst (0)
| 1 | ... | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 RJT09_06830   Segatella copri H-2632 MDV3106180.1     4
 RJT09_06835   Segatella copri H-2632 MDV3106181.1     4
 KUA49_013400   Segatella copri HDE06 WOZ84137.1     4
 KUA49_000035   Segatella copri HDE06 WOZ84844.1     4
 KUA49_013385   Segatella copri HDE06 WOZ84134.1     4
 RJT13_00045   Segatella copri N-01 MDV3120051.1     4
 RJT13_01155   Segatella copri N-01 MDV3120266.1     4
 FO447_01530   Segatella copri YF2 QNT65320.1     4
 FO447_01485   Segatella copri YF2 QNT65311.1     4
 FO447_01480   Segatella copri YF2 QNT65310.1     4
 FO447_00140   Segatella copri YF2 QNT65075.1     4
 KUA50_002265   Segatella hominis HDD12 WOZ81812.1     4
 KUA50_000030   Segatella hominis HDD12 WOZ81389.1     4
 KUA50_002300   Segatella hominis HDD12 WOZ81818.1     4
 NCTC13071_02043 (CelA)   Segatella oris NCTC13071 VEH16026.1     4
 U5921_07515   Sinanaerobacter sp. ZZT-01 WRR94959.1     4
 LS482_07300   Sinomicrobium kalidii HD2P242 UGU17674.1     4
 O7608_26700   Solwaraspora sp. WMMA2056 WJK39987.1     4
 O7553_06335   Solwaraspora sp. WMMA2059 WBB98531.1     4
 O7610_01140   Solwaraspora sp. WMMA2065 WJK35042.1     4
 O7543_11030   Solwaraspora sp. WMMA2080 WBC22917.1     4
 O7623_29680   Solwaraspora sp. WMMD791 WFE27347.1     4
 O7623_22085   Solwaraspora sp. WMMD791 WFE26030.1     4
 O7621_14975   Solwaraspora sp. WMMD937 WFE19264.1     4
 SOCE26_013110   Sorangium cellulosum So ce26 AUX39916.1     4
 sce0902   Sorangium cellulosum So ce56 CAN91059.1     4
 SOCE836_105280   Sorangium cellulosum So ce836 AUX38287.1     4
 SOCEGT47_045950   Sorangium cellulosum So ceGT47 AUX24062.1     4
 SCE1572_51055   Sorangium cellulosum So0157-2 AGP42124.1     4
 NQZ70_10368   Sorangium sp. Soce836 WCQ97574.1     4
 G6053_15845   Sphingobacterium sp. DR205 QIH34270.1     4
 OGI71_12530   Sphingobacterium sp. ML3W WFA82123.1     4
 NCTC11429_03621 (Cela_1)   Sphingobacterium thalpophilum NCTC11429 VTR48042.1     4
 H9L15_10995 (fragment)   Sphingomonas daechungensis KACC 18115 QNP42676.1     4
 H9L15_11000 (fragment)   Sphingomonas daechungensis KACC 18115 QNP42677.1     4
 PIB19_05370   Sphingomonas sp. 7/4-4 WBY08850.1     4
 KNJ79_12115 (fragment)   Sphingopyxis indica MC4 WOF41976.1     4
 G5C33_10715   Sphingosinithalassobacter tenebrarum zrk23 QIG80205.1     4
 FOC63_05645   Streptococcus gallolyticus FDAARGOS_755 QKI01015.1     4
 NCTC13773_00443 (CeL)   Streptococcus gallolyticus NCTC13773 SQG78665.1     4
 SGGB_0358 (CeL)   Streptococcus gallolyticus subsp. gallolyticus ATCC 43143 BAK27255.1     4
 SGGBAA2069_c03180 (CelB)   Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069 CBZ47490.1     4
 BTR42_01930   Streptococcus gallolyticus subsp. gallolyticus DSM 16831 AQP41385.1     4
 JGX27_01735   Streptococcus gallolyticus subsp. gallolyticus TX20005 QWX87086.1     4
 GALLO_0330   Streptococcus gallolyticus UCN34 CBI12822.1     4
 OIY87_03105   Streptococcus gallolyticus XH2168 WAW99347.1     4
 DMT42_32545   Streptomyces actuosus ATCC 25421 AWT47895.1     4
 K1J60_43490   Streptomyces akebiae MG28 QYX82505.1     4
 G9272_01885   Streptomyces asoensis H2S5 QJS99217.1     4
 SBI_09923   Streptomyces bingchenggensis BCW-1 ADI13041.1     4
 SBI_09963   Streptomyces bingchenggensis BCW-1 ADI13081.1     4
 SBI_00359 (fragment)   Streptomyces bingchenggensis BCW-1 ADI03480.1     4
 EJC51_02765   Streptomyces brunneus CR22 AZP15134.1     4
 IHE65_43465   Streptomyces caniscabiei ID-03-3A WEO29490.1     4
 IHE65_40570   Streptomyces caniscabiei ID-03-3A WEO28958.1     4
 OG925_05440   Streptomyces canus NBC_01585 WSD83767.1     4
 OG925_14475   Streptomyces canus NBC_01585 WSD85427.1     4
 N0X72_26075   Streptomyces carpaticus SCPM-O-B-9993 UWM52205.1     4
 NRO40_27050   Streptomyces changanensis HL-66 UUS34123.1     4
 CP976_00710   Streptomyces coeruleorubidus ATCC 13740 QEV22844.1     4
 PV963_01870   Streptomyces coeruleorubidus DM WDV49276.1     4
 PV963_40270   Streptomyces coeruleorubidus DM WDV56135.1     4
 R5U08_37255   Streptomyces coeruleorubidus WT-48 WOT39453.1     4
 QU709_44155   Streptomyces coralus SX92 WLW57943.1     4
 EJ357_45620   Streptomyces cyaneochromogenes MK-45 AZQ39810.1     4
 N8I84_34630   Streptomyces cynarae HUAS 13-4 UXY23265.1     4
 N8I84_33005   Streptomyces cynarae HUAS 13-4 UXY22983.1     4
 BN159_0466 (Celb1)   Streptomyces davaonensis JCM 4913 CCK24845.1     4
 L3078_01930   Streptomyces deccanensis KCTC 19241 ULR48137.1     4
 SGFS_024490   Streptomyces graminofaciens A-8890 BBC31155.1     4
 DWG14_08147 (EngD)   Streptomyces griseorubiginosus 3E-1 AYC43839.1     4
 CEB94_39905   Streptomyces hawaiiensis ATCC 12236 QCD60242.1     4
 CEB94_04740   Streptomyces hawaiiensis ATCC 12236 QCD54238.1     4
 CEB94_04355   Streptomyces hawaiiensis ATCC 12236 QCD54178.1     4
 RI060_37240   Streptomyces janthinus JCM 4387 WND22659.1     4
 GJU35_03690   Streptomyces lincolnensis B48 QMV12142.1     4
 SLCG_0690   Streptomyces lincolnensis LC-G AXG51845.1     4
 SLINC_0697   Streptomyces lincolnensis NRRL 2936 ANS62921.1     4
 SLINC_8289 (fragment)   Streptomyces lincolnensis NRRL 2936 ANS70513.1     4
 SLINC_8278   Streptomyces lincolnensis NRRL 2936 ANS70502.1     4
 LC193_16485   Streptomyces marincola SCSIO 64649 UCM89417.1     4
 A4E84_04105   Streptomyces qaidamensis S10(2016) AMW15165.1     4
 IAG44_41830   Streptomyces roseirectus CRXT-G-22 QNP75306.1     4
 SCAB_86471   Streptomyces scabiei 87.22 CBG75588.1     4
 P8T65_45720   Streptomyces sp. 11x1 WNZ14147.1     4
 SAMN05444521_0298   Streptomyces sp. 3214.6 SHH37621.1     4
 IOD14_23340   Streptomyces sp. A2-16 QUC59446.1     4
 CVT30_45400   Streptomyces sp. AMCC400023 UJV46137.1     4
 CVT30_44280   Streptomyces sp. AMCC400023 UJV45952.1     4
 JIX56_01040   Streptomyces sp. CA-210063 UUU28598.1     4
 C2142_36725   Streptomyces sp. CB01881 AUY53505.1     4
 AS200_05365   Streptomyces sp. CdTB01 ALV31540.1     4
 VJ737_36760   Streptomyces sp. CGMCC 4.1772 WRU02904.1     4
 AA958_27115   Streptomyces sp. CNQ-509 AKH87057.1     4
 V8690_01855   Streptomyces sp. DG1A-41 WWT93392.1     4
 JIX55_05860   Streptomyces sp. DSM 40750 UUU19863.1     4
 Q7C01_22215   Streptomyces sp. FXY-T5 WMD06924.1     4
 C1703_36990 (Engd3)   Streptomyces sp. Go-475 AXE90646.1     4
 C1703_02490 (Cela2)   Streptomyces sp. Go-475 AXE83850.1     4
 C1703_35925 (Engd2)   Streptomyces sp. Go-475 AXE90434.1     4
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