Glycoside Hydrolase Family 5 / Subf 4

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (596); Uniprot accession (185); PDB accession (34); 3D entries (16); cryst (0)
| 1 | 2 | 3 | 4 | 5 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 SAMN04489716_1697   Actinoplanes derwentensis DSM 43941 SDS81858.1     4
 SAMN04489716_5708   Actinoplanes derwentensis DSM 43941 SDT69013.1     4
 AFR_12400   Actinoplanes friuliensis DSM 7358 AGZ40766.1     4
 AMIS_9970   Actinoplanes missouriensis 431 BAL86217.1     4
 AMIS_49860   Actinoplanes missouriensis 431 BAL90206.1     4
 L083_4706   Actinoplanes sp. N902-109 AGL18216.1     4
 ACPL_6130   Actinoplanes sp. SE50/110 AEV87015.1
SLM02825.1
    4
 SAMN04489717_1670   Actinopolymorpha singaporensis DSM 22024 SDS11517.1     4
 Amir_2781   Actinosynnema mirum DSM 43827 ACU36714.1 C6WP45   4
 Amir_3335   Actinosynnema mirum DSM 43827 ACU37240.1 C6W9M3   4
 CNX65_14080   Actinosynnema pretiosum X47 ATE54282.1     4
 CDL62_13665   Alkalitalea saponilacus DSM 24412 ASB50110.1     4
 B737_7271   Amycolatopsis mediterranei RB AGT87932.1     4
 RAM_37950   Amycolatopsis mediterranei S699 AEK46057.1
AFO80804.1
    4
 AMED_7382   Amycolatopsis mediterranei U32 ADJ49096.1 D8I9C9   4
 SD37_17825   Amycolatopsis orientalis B-37 ANN17321.1     4
 BEQ56_08495   Anaerolineaceae bacterium oral taxon 439 W11661 AOH43511.1     4
 Astex_3212   Asticcacaulis excentricus CB 48 ADU14847.1 C5SP55   4
 Bcell_1191   Bacillus cellulosilyticus DSM 2522 ADU29456.1 D2LUH5   4
 BGLY_1876   Bacillus glycinifermentans SCA85699.1     4
 β-glucanase (CelB;BhCel5B;BH0603) (Cel5B) 3.2.1.4 Bacillus halodurans C-125 BAB04322.1
NP_241469.1
Q9KF82 4V2X[A] 4
 Cellulase (fragment)   Bacillus halodurans TSPV1 ALL28250.1     4
 BL1202_02034   Bacillus licheniformis BL1202 AOP14982.1     4
 endoglucanase (BlCel5B;BLi01882;BL01230) (Cel5B) 3.2.1.4 Bacillus licheniformis DSM 13 = ATCC 14580 AAU40777.1
AAU23417.1
Q65JI7 4YZP[A]
4YZT[A]
4
 CelB   Bacillus licheniformis F11 CAJ70720.1 Q5K2M0   4
 CelB   Bacillus licheniformis F5 CAJ70717.1 Q5K2M0   4
 AB684_08870   Bacillus licheniformis HRBL-15TDI7 AMR10287.1     4
 CelB   Bacillus licheniformis MD1 CAH10344.1 Q5K2M0   4
 Cel5C (Cel5C)   Bacillus licheniformis MSB03 ACY72382.1 D1L8C7   4
 B37_01401 (EngD)   Bacillus licheniformis SCCB 37 ARC73453.1     4
 B14_02581 (EngD)   Bacillus licheniformis SCDB 14 ARC65579.1     4
 B34_00221 (EngD)   Bacillus licheniformis SCDB 34 ARC67664.1     4
 BaDB11_04388 (EngD)   Bacillus licheniformis SCK B11 ARC62951.1     4
 S100141_01268   Bacillus licheniformis SRCM100141 ARW42590.1     4
 glycoside hydrolase (Gh5B)   Bacillus licheniformis SVD1 BAL45505.1     4
 MUY_001893 (CelC)   Bacillus licheniformis WX-02 AKQ73025.1     4
 BaLi_c19160 (CelB)   Bacillus paralicheniformis ATCC 9945a AGN36284.1     4
 SC10_B2orf02856   Bacillus paralicheniformis BL-09 AJO18129.1     4
 BLMD_09335   Bacillus paralicheniformis MDJK30 ARA85656.1     4
 S101395_03070   Bacillus sonorensis SRCM101395 ASB89577.1     4
 CJO35_09285   Bacillus sp. 1s-1 ASV15340.1     4
 cellulase (CelB) 3.2.1.4 Bacillus sp. BG-CS10 ADD62401.1 D4P8C6 5E09[A]
5E0C[A]
4
 unnamed protein product   Bacillus sp. CBS 669.93 AAE86309.1
AAV25062.1
CAD82874.1
    4
 BSZ43_09215   Bacillus sp. H15-1 APJ26960.1     4
 cellulase   bacterium enrichment culture AJO67866.1     4
 BcellWH2_03343 (Cela_1)   Bacteroides cellulosilyticus WH2 ALJ60576.1     4
 BcellWH2_03344 (Cela_2)   Bacteroides cellulosilyticus WH2 ALJ60577.1     4
 endo-xyloglucanase (CelA;BoGH5A;BACOVA_02653;Bovatus_03072) 3.2.1.151 Bacteroides ovatus ATCC 8483 ALJ47680.1   3ZMR[A,B] 4
 BACOV975_00834   Bacteroides ovatus V975 SCV07078.1     4
 Bacsa_0886   Bacteroides salanitronis DSM 18170 ADY35478.1     4
 endo-cellulase (AC2aCel5A) (Cel5A) 3.2.1.4 Bacteroidetes bacterium AC2a AIJ19564.1   4YHE[A,B] 4
 BDP_2147   Bifidobacterium dentium Bd1 ADB10705.1 D2Q7E3   4
 BDP_2148   Bifidobacterium dentium Bd1 ADB10706.1 D2Q7E4   4
 BBDE_2018   Bifidobacterium dentium JCM 1195 = DSM 20436 BAQ28012.1     4
 BBDE_2017   Bifidobacterium dentium JCM 1195 = DSM 20436 BAQ28011.1     4
 CIY_21980   Butyrivibrio fibrisolvens 16/4 CBK74879.1 D4IVT6   4
 endo-β-1,4-glucanase 1 (End1;EglI;EGI) 3.2.1.4
3.2.1.73
Butyrivibrio fibrisolvens H17C CAA35574.1 P20847   4
 bhn_I0165   Butyrivibrio hungatei MB2003 AOZ95201.1     4
 bhn_I1693   Butyrivibrio hungatei MB2003 AOZ96726.1     4
 bpr_I1710 (Cel5C)   Butyrivibrio proteoclasticus B316 ADL34447.1 E0RXM0 4NF7[A] 4
 bpr_I0299   Butyrivibrio proteoclasticus B316 ADL33047.1 E0RYG6   4
 bpr_I0728   Butyrivibrio proteoclasticus B316 ADL33471.1 E0S0Z6   4
 β-1,3-1,4-glucanase / lichenase   Caldicellulosiruptor sp. F32 AGM71677.1   4X0V[A,B,C,D,E,F,G,H]
5H4R[A]
4
 Caci_4876   Catenulispora acidiphila DSM 44928 ACU73736.1 C7Q1K7   4
 Caci_4946   Catenulispora acidiphila DSM 44928 ACU73806.1 C7Q370   4
 Caci_5006   Catenulispora acidiphila DSM 44928 ACU73866.1 C7Q3D0   4
 Celf_0376   Cellulomonas fimi ATCC 484 AEE44521.1     4
 endoglucanase / xylanase (CGSCsYakCAS_09989) (Cel5A) 3.2.1.- Cellulosilyticum ruminicola CGMCC 1.5065 ACZ98591.1 D2KFI9   4
 CGSCsYakCAS_00694   Cellulosilyticum ruminicola CGMCC 1.5065 ACZ98603.1 D2KFK1   4
 CGSCsYakCAS_19105   Cellulosilyticum ruminicola CGMCC 1.5065 ACZ98607.1 D2KFK5   4
 CGSCsYakCAS_19240 (fragment)   Cellulosilyticum ruminicola CGMCC 1.5065 ACZ98609.1 D2KFK7   4
 CJA_3337 (Cel5E)   Cellvibrio japonicus Ueda107 ACE83841.1 B3PF23   4
 CJA_3010 (Cel5D)   Cellvibrio japonicus Ueda107 ACE84905.1 B3PD52   4
 CJA_2959 (Cel5F)   Cellvibrio japonicus Ueda107 ACE86198.1 B3PCP9   4
 CBR65_03720   Cellvibrio sp. PSBB006 ARU26604.1     4
 CBR65_03365   Cellvibrio sp. PSBB006 ARU26534.1     4
 B0D95_10735   Cellvibrio sp. PSBB023 AQT62398.1     4
 B0D95_02165   Cellvibrio sp. PSBB023 AQT59026.1     4
 endo-/exo-type cellulase (CelEdx16) 3.2.1.4 Clostridiaceae bacterium AN-C16-KBRB ADK66823.1 E0A3Q5   4
 CAC3469   Clostridium acetobutylicum ATCC 824 AAK81397.1
NP_350057.1
Q97DK6   4
 CAC0826   Clostridium acetobutylicum ATCC 824 AAK78802.1
NP_347462.1
Q97KU0   4
 CAC0825   Clostridium acetobutylicum ATCC 824 AAK78801.1
NP_347461.1
Q97KU1   4
 SMB_G3507   Clostridium acetobutylicum DSM 1731 AEI34646.1     4
 SMB_G0841 (EngD)   Clostridium acetobutylicum DSM 1731 AEI34705.1     4
 SMB_G0842 (EngD)   Clostridium acetobutylicum DSM 1731 AEI34706.1     4
 CEA_G3473   Clostridium acetobutylicum EA 2018 ADZ22510.1     4
 CEA_G0836   Clostridium acetobutylicum EA 2018 ADZ19875.1     4
 CEA_G0837   Clostridium acetobutylicum EA 2018 ADZ19876.1     4
 CM240_2767   Clostridium bornimense M2/40 CDM69884.1     4
 CM240_3204 (CelA1) (partial)   Clostridium bornimense M2/40 CDM70321.1     4
 endo-β-1,4-glucanase A (CelA;Cca;CelCcaCcel_1099) (Cel5A) 3.2.1.4 [Clostridium] cellulolyticum H10 AAA23221.1
AAA51444.1
ACL75458.1
P17901 1EDG[A] 4
 xyloglucanase (Xyg5A)   Clostridium cellulovorans BAV13070.1     4
 endoglucanase (Eng5B)   Clostridium cellulovorans BAV13031.1     4
 endoglucanase (Eng5C)   Clostridium cellulovorans BAV13032.1     4
 endoglucanase (Eng5G)   Clostridium cellulovorans BAV13065.1     4
 endo-β-1,4-glucanase / xylanase B (EngB;Clocel_1150) 3.2.1.4
3.2.1.73
3.2.1.8
Clostridium cellulovorans 743B AAA23231.1
ADL50906.1
C5RHC3
P28621
  4
 Clocel_0912   Clostridium cellulovorans 743B ADL50682.1 D9ST66   4
 Clocel_1432   Clostridium cellulovorans 743B ADL51185.1 D9SW41   4
 Clocel_2606   Clostridium cellulovorans 743B ADL52313.1 D9SQV7   4
 Clocel_3111   Clostridium cellulovorans 743B ADL52801.1 D9STR7   4
Top




Last update: 2017-10-09 © Copyright 1998-2017
AFMB - CNRS - Université d'Aix-Marseille