| Activities in Sub Family | glucomannan-specific endo-β-1,4-glucanase (EC 3.2.1.-);oligoxyloglucan reducing-end-specific cellobiohydrolase (EC 3.2.1.150);xyloglucan-specific endo-β-1,4-glucanase / endo-xyloglucanase (EC 3.2.1.151);endo-β-1,4-glucanase (EC 3.2.1.4);endo-β-1,3(4)-glucanase / lichenase-laminarinase (EC 3.2.1.6);lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73);endo-β-1,4-mannanase (EC 3.2.1.78);endo-β-1,4-xylanase (EC 3.2.1.8) |
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| Mechanism | Retaining |
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| Clan | GH-A |
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| 3D Structure Status | ( β / α ) 8 barrel |
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| Catalytic Nucleophile/Base | Glu (experimental) |
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| Catalytic Proton Donor | Glu (experimental) |
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| Note | Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189). |
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| External resources | CAZypedia; HOMSTRAD; PROSITE; |
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| Commercial Enzyme Provider(s) | MEGAZYME; NZYTech; PROZOMIX; |
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| Statistics | GenBank accession (1307); Uniprot accession (139); PDB accession (53); 3D entries (27); cryst (0) |
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