Glycoside Hydrolase Family 5 / Subf 13

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (572); Uniprot accession (47);
All (550) Archaea (1) Bacteria (549)
| 1 | 2 | 3 | 4 | 5 | 6 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 ECR091_02795   Enterobacter hormaechei subsp. hoffmannii ECR091 AIN26613.1     13
 LI66_02810   Enterobacter hormaechei subsp. oharae 34399 AJB80335.1     13
 LI63_005215   Enterobacter hormaechei subsp. oharae 34978 ALA00691.1     13
 BFV66_02875   Enterobacter hormaechei subsp. oharae DSM 16687 AOP80994.1     13
 LI62_03285   Enterobacter hormaechei subsp. steigerwaltii 34977 AJB61120.1     13
 LI65_003920   Enterobacter hormaechei subsp. steigerwaltii 34998 AKZ82740.1     13
 BFV68_02760   Enterobacter hormaechei subsp. steigerwaltii DSM 16691 AOP76594.1     13
 BFV63_02765   Enterobacter hormaechei subsp. xiangfangensis LMG27195 AOP89869.1     13
 CUN65_20400   Enterobacter hormaechei subsp. xiangfangensis OSUKPC4_L AWR70563.1     13
 DF208_20325   Enterobacter hormaechei subsp. xiangfangensis OSUVMCKPC4-2 AXM01359.1     13
 DN066_21265   Enterobacter hormaechei subsp. xiangfangensis Pb204 AWV77786.1     13
 D0Z05_19230   Enterobacter hormaechei WCHEH020038 AXQ35400.1     13
 BFV64_02445   Enterobacter kobei DSM 13645 AOP85282.1     13
 BH714_17450   Enterobacter ludwigii EN-119 AOT44902.1     13
 BFV67_02610   Enterobacter roggenkampii DSM 16690 AOP94116.1     13
 B7P19_02485   Enterobacter sp. Crenshaw AUM02101.1     13
 CU081_00735   Enterobacter sp. CRENT-193 ATW90300.1     13
 A4308_00055   Enterobacter sp. ODB01 AMZ75482.1     13
 F652_2260   Enterobacteriaceae bacterium bta3-1 AJR00250.1     13
 D782_2977   Enterobacteriaceae bacterium strain FGI 57 AGB78929.1     13
 ING2E5B_1384   Fermentimonas caenicola CEA16132.1     13
 FAES_0150   Fibrella aestuarina BUZ 2 CCG98164.1     13
 A6C57_15815   Fibrella sp. ES10-3-2-2 ARK11678.1     13
 A6C57_15485   Fibrella sp. ES10-3-2-2 ARK13688.1     13
 FLA_0217   Filimonas lacunae NBRC 104114 BAV04238.1     13
 D770_24630   Flammeovirgaceae bacterium 311 AHM63171.1     13
 SY85_01885   Flavisolibacter tropicus LCS9 ANE49435.1     13
 SAMN03097699_0409   Flavobacteriaceae bacterium MAR_2010_188 SDB26987.1     13
 BB050_04142   Flavobacterium johnsoniae GSE09 AOC97220.1     13
 Fjoh_2022   Flavobacterium johnsoniae UW101 ABQ05053.1 A5FIB3   13
 HYN56_15495   Flavobacterium sp. HYN0056 AWK07461.1     13
 GRFL_0301   Gramella flava JLT2011 APU67025.1     13
 AciX9_1836   Granulicella tundricola MP5ACTX9 ADW68883.1     13
 AL518_10060   Hafnia alvei FDAARGOS_158 AMH18328.1     13
 DDQ68_07955   Hymenobacter nivis NBRC 111535 AWM32721.1     13
 DDQ68_01385 (fragment)   Hymenobacter nivis NBRC 111535 AWM31558.1     13
 AUC43_19220   Hymenobacter sedentarius DG5B ALW87464.1     13
 PK28_16840   Hymenobacter sp. DG25B AIZ65347.1     13
 A0257_18395   Hymenobacter sp. PAMC 26554 AMR28871.1     13
 A0257_20910   Hymenobacter sp. PAMC 26554 AMR29884.1     13
 AXW84_13375   Hymenobacter sp. PAMC 26628 AMJ66315.1     13
 Hsw_2709   Hymenobacter swuensis DY53 AHJ98304.1     13
 ATN83_2623   Klebsiella pneumoniae Yangling I2 ALQ46738.1     13
 A8A57_02810   Lelliottia amnigena ZB04 ANG91378.1     13
 LJPFL01_0547   Lelliottia jeotgali PFL01 ASV53910.1     13
 CWR52_09480   Lelliottia nimipressuralis SGAir0187 AVH17418.1     13
 DAI21_01595   Lelliottia sp. WB101 AVY96476.1     13
 CJ263_16055   Maribacter cobaltidurans B1 ASV31605.1     13
 CJ263_05455   Maribacter cobaltidurans B1 ASV29706.1     13
 FB2170_13658   Maribacter sp. HTCC2170 EAR01578.1 A4AQ39   13
 ABE85_17925   Mitsuaria sp. 7 ANH68980.1     13
 MgSA37_02323   Mucilaginibacter gotjawali SA3-7 BAU54151.1     13
 SAMN05216490_2574   Mucilaginibacter mallensis MP1X4 SDT13937.1     13
 MuYL_3128   Mucilaginibacter sp. BJC16-A31 ASU35013.1     13
 A0256_23485   Mucilaginibacter sp. PAMC 26640 AMR34201.1     13
 MAV_0332   Mycobacterium avium 104 ABK65310.1 A0Q9N1   13
 BBJ32_10830   Mycobacterium avium RCAD0278 ANR91726.1     13
 BBJ32_19775   Mycobacterium avium RCAD0278 ANR94157.1     13
 LA63_01560   Mycobacterium avium subsp. avium 2285 (R) AIR54763.1     13
 LA63_10295   Mycobacterium avium subsp. avium 2285 (R) AIR56378.1     13
 LA64_01570   Mycobacterium avium subsp. avium 2285 (S) AIR21948.1     13
 LA64_10325   Mycobacterium avium subsp. avium 2285 (S) AIR23561.1     13
 NF84_10080   Mycobacterium avium subsp. avium DJO-44271 AIV27416.1     13
 NF84_01515   Mycobacterium avium subsp. avium DJO-44271 AIV23476.1     13
 BS641_01450   Mycobacterium avium subsp. hominissuis H87 APT09157.1     13
 BS641_13290   Mycobacterium avium subsp. hominissuis H87 APT13643.1     13
 BEP52_01390   Mycobacterium avium subsp. hominissuis HP17 ATO61111.1     13
 BEP52_15080   Mycobacterium avium subsp. hominissuis HP17 ATO63467.1     13
 DFS55_15080   Mycobacterium avium subsp. hominissuis MAC109 AXO23750.1     13
 DFS55_23375   Mycobacterium avium subsp. hominissuis MAC109 AXO25184.1     13
 KV38_09485   Mycobacterium avium subsp. hominissuis OCU464 APA75587.1     13
 KV38_01400   Mycobacterium avium subsp. hominissuis OCU464 APA74089.1     13
 BJP74_01375   Mycobacterium avium subsp. hominissuis OCU873s_P7_4s ATO70246.1     13
 BJP74_10770   Mycobacterium avium subsp. hominissuis OCU873s_P7_4s ATO74275.1     13
 BJP78_14845   Mycobacterium avium subsp. hominissuis OCU901s_S2_2s ATO68002.1     13
 BJP78_01345   Mycobacterium avium subsp. hominissuis OCU901s_S2_2s ATO65671.1     13
 MAH_0298   Mycobacterium avium subsp. hominissuis TH135 BAN29372.1     13
 MAH_2863   Mycobacterium avium subsp. hominissuis TH135 BAN31937.1     13
 RC58_09270   Mycobacterium avium subsp. paratuberculosis E1 AJK77531.1     13
 RC58_17820   Mycobacterium avium subsp. paratuberculosis E1 AJK76651.1     13
 RE97_09275   Mycobacterium avium subsp. paratuberculosis E93 AJK81767.1     13
 RE97_17855   Mycobacterium avium subsp. paratuberculosis E93 AJK80864.1     13
 CEP84_16240   Mycobacterium avium subsp. paratuberculosis FDAARGOS_305 ASE16512.1     13
 CEP84_02195   Mycobacterium avium subsp. paratuberculosis FDAARGOS_305 ASE12782.1     13
 CEG92_10260   Mycobacterium avium subsp. paratuberculosis JII-1961 ASF98472.1     13
 CEG92_01490   Mycobacterium avium subsp. paratuberculosis JII-1961 ASF94595.1     13
 MAP0285c   Mycobacterium avium subsp. paratuberculosis K-10 AAS02602.1
NP_959219.1
    13
 MAP1971   Mycobacterium avium subsp. paratuberculosis K-10 AAS04288.1
NP_960905.1
    13
 A0V42_10030   Mycobacterium avium subsp. paratuberculosis MAP/TANUVAS/TN/India/2008 ANH31013.1     13
 A0V42_01440   Mycobacterium avium subsp. paratuberculosis MAP/TANUVAS/TN/India/2008 ANH27158.1     13
 MAP4_1855   Mycobacterium avium subsp. paratuberculosis MAP4 AGL36773.1     13
 MAP4_3586   Mycobacterium avium subsp. paratuberculosis MAP4 AGL38447.1     13
 MCAN_31221   Mycobacterium canettii CIPT 140010059 CCC45453.1     13
 BN44_60613   Mycobacterium canettii CIPT 140060008 CCK53094.1     13
 BN43_60089   Mycobacterium canettii CIPT 140070008 CCK57148.1     13
 BN42_41113   Mycobacterium canettii CIPT 140070010 CCK61203.1     13
 BN45_60085   Mycobacterium canettii CIPT 140070017 CCK65281.1     13
 AN480_01475   Mycobacterium chimaera AH16 AOS90437.1     13
 AN480_11420   Mycobacterium chimaera AH16 AOS91920.1     13
 MYCODSM44623_00305   Mycobacterium chimaera DSM 44623 ASL07088.1     13
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