Glycoside Hydrolase Family 5 / Subf 13

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (488); Uniprot accession (47);
All (466) Archaea (1) Bacteria (465)
| 1 | 2 | 3 | 4 | 5 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 PK28_16840   Hymenobacter sp. DG25B AIZ65347.1     13
 A0257_18395   Hymenobacter sp. PAMC 26554 AMR28871.1     13
 A0257_20910   Hymenobacter sp. PAMC 26554 AMR29884.1     13
 AXW84_13375   Hymenobacter sp. PAMC 26628 AMJ66315.1     13
 Hsw_2709   Hymenobacter swuensis DY53 AHJ98304.1     13
 ATN83_2623   Klebsiella pneumoniae Yangling I2 ALQ46738.1     13
 A8A57_02810   Lelliottia amnigena ZB04 ANG91378.1     13
 LJPFL01_0547   Lelliottia sp. PFL01 ASV53910.1     13
 CJ263_16055   Maribacter sp. B1 ASV31605.1     13
 CJ263_05455   Maribacter sp. B1 ASV29706.1     13
 FB2170_13658   Maribacter sp. HTCC2170 EAR01578.1 A4AQ39   13
 ABE85_17925   Mitsuaria sp. 7 ANH68980.1     13
 MgSA37_02323   Mucilaginibacter gotjawali SA3-7 BAU54151.1     13
 SAMN05216490_2574   Mucilaginibacter mallensis MP1X4 SDT13937.1     13
 MuYL_3128   Mucilaginibacter sp. BJC16-A31 ASU35013.1     13
 A0256_23485   Mucilaginibacter sp. PAMC 26640 AMR34201.1     13
 RN09_3760   Mycobacterium africanum 25 AMC65508.1     13
 MAF_31030   Mycobacterium africanum GM041182 CCC28173.1     13
 AZ248_16480   Mycobacterium africanum UT307 AMQ39794.1     13
 MAV_0332   Mycobacterium avium 104 ABK65310.1 A0Q9N1   13
 BBJ32_10830   Mycobacterium avium RCAD0278 ANR91726.1     13
 BBJ32_19775   Mycobacterium avium RCAD0278 ANR94157.1     13
 LA63_01560   Mycobacterium avium subsp. avium 2285 (R) AIR54763.1     13
 LA63_10295   Mycobacterium avium subsp. avium 2285 (R) AIR56378.1     13
 LA64_01570   Mycobacterium avium subsp. avium 2285 (S) AIR21948.1     13
 LA64_10325   Mycobacterium avium subsp. avium 2285 (S) AIR23561.1     13
 NF84_10080   Mycobacterium avium subsp. avium DJO-44271 AIV27416.1     13
 NF84_01515   Mycobacterium avium subsp. avium DJO-44271 AIV23476.1     13
 BS641_01450   Mycobacterium avium subsp. hominissuis H87 APT09157.1     13
 BS641_13290   Mycobacterium avium subsp. hominissuis H87 APT13643.1     13
 KV38_09485   Mycobacterium avium subsp. hominissuis OCU464 APA75587.1     13
 KV38_01400   Mycobacterium avium subsp. hominissuis OCU464 APA74089.1     13
 MAH_0298   Mycobacterium avium subsp. hominissuis TH135 BAN29372.1     13
 MAH_2863   Mycobacterium avium subsp. hominissuis TH135 BAN31937.1     13
 RC58_09270   Mycobacterium avium subsp. paratuberculosis E1 AJK77531.1     13
 RC58_17820   Mycobacterium avium subsp. paratuberculosis E1 AJK76651.1     13
 RE97_09275   Mycobacterium avium subsp. paratuberculosis E93 AJK81767.1     13
 RE97_17855   Mycobacterium avium subsp. paratuberculosis E93 AJK80864.1     13
 CEP84_16240   Mycobacterium avium subsp. paratuberculosis FDAARGOS_305 ASE16512.1     13
 CEP84_02195   Mycobacterium avium subsp. paratuberculosis FDAARGOS_305 ASE12782.1     13
 CEG92_10260   Mycobacterium avium subsp. paratuberculosis JII-1961 ASF98472.1     13
 CEG92_01490   Mycobacterium avium subsp. paratuberculosis JII-1961 ASF94595.1     13
 MAP0285c   Mycobacterium avium subsp. paratuberculosis K-10 AAS02602.1
NP_959219.1
    13
 MAP1971   Mycobacterium avium subsp. paratuberculosis K-10 AAS04288.1
NP_960905.1
    13
 A0V42_10030   Mycobacterium avium subsp. paratuberculosis MAP/TANUVAS/TN/India/2008 ANH31013.1     13
 A0V42_01440   Mycobacterium avium subsp. paratuberculosis MAP/TANUVAS/TN/India/2008 ANH27158.1     13
 MAP4_1855   Mycobacterium avium subsp. paratuberculosis MAP4 AGL36773.1     13
 MAP4_3586   Mycobacterium avium subsp. paratuberculosis MAP4 AGL38447.1     13
 Mb1595_p3446   Mycobacterium bovis 1595 AKR02969.1     13
 RN07_3308   Mycobacterium bovis 30 AMC56539.1     13
 Mb3123   Mycobacterium bovis AF2122/97 SIU01748.1
CAD96810.1
CDO44392.1
NP_856768.1
    13
 LH58_16480   Mycobacterium bovis ATCC BAA-935 AIR48318.1     13
 RN06_3751   Mycobacterium bovis BCG 26 AMC52204.1     13
 GS11_3240   Mycobacterium bovis BCG 3281 AKO26166.1     13
 BCGR_3363   Mycobacterium bovis BCG Russia 368 ALA79680.1     13
 BCGT_2947   Mycobacterium bovis BCG str. ATCC 35743 63839 AHM08866.1     13
 K60_032130   Mycobacterium bovis BCG str. Korea 1168P AGE69123.1     13
 BCGMEX_3118   Mycobacterium bovis BCG str. Mexico AET20389.1     13
 BCGM_3105 (Bcgm3105)   Mycobacterium bovis BCG str. Moreau RDJ CCC65698.1     13
 BCG_3121   Mycobacterium bovis BCG str. Pasteur 1173P2 CAL73110.1 A1KN94   13
 JTY_3116   Mycobacterium bovis BCG str. Tokyo 172 BAH27394.1 C1AGL5   13
 AZH48_16000   Mycobacterium bovis BCG str. Tokyo 172 substrain TRCS AMO11441.1     13
 AA885_16120   Mycobacterium bovis BCG-1 ALE44663.1     13
 BOVR_16035   Mycobacterium bovis BCG-1 (Russia) ALV12037.1     13
 SZ58_010915   Mycobacterium bovis SP38 ANG88769.1     13
 MCAN_31221   Mycobacterium canettii CIPT 140010059 CCC45453.1     13
 BN44_60613   Mycobacterium canettii CIPT 140060008 CCK53094.1     13
 BN43_60089   Mycobacterium canettii CIPT 140070008 CCK57148.1     13
 BN42_41113   Mycobacterium canettii CIPT 140070010 CCK61203.1     13
 BN45_60085   Mycobacterium canettii CIPT 140070017 CCK65281.1     13
 BBG46_16145   Mycobacterium caprae Allgaeu APU26985.1     13
 GR01_23470   Mycobacterium chelonae ATCC 35752 AKC40943.1     13
 BB28_24455   Mycobacterium chelonae CCUG 47445 ANB00698.1     13
 AN480_01475   Mycobacterium chimaera AH16 AOS90437.1     13
 AN480_11420   Mycobacterium chimaera AH16 AOS91920.1     13
 MYCODSM44623_00305   Mycobacterium chimaera DSM 44623 ASL07088.1     13
 MYCODSM44623_02411 (fragment)   Mycobacterium chimaera DSM 44623 ASL09142.1     13
 CKJ58_10375   Mycobacterium chimaera FLAC0070 ASX03146.1     13
 CKJ58_02000   Mycobacterium chimaera FLAC0070 ASW98822.1     13
 CE197_01545   Mycobacterium chimaera SJ42 ASQ84489.1     13
 CE197_10770   Mycobacterium chimaera SJ42 ASQ89149.1     13
 MYCOZU1_02534 (fragment)   Mycobacterium chimaera ZUERICH-1 ASL20957.1     13
 MYCOZU1_00448   Mycobacterium chimaera ZUERICH-1 ASL18926.1     13
 MYCOZU2_00303   Mycobacterium chimaera ZUERICH-2 ASL12770.1     13
 MYCOZU2_02464 (fragment)   Mycobacterium chimaera ZUERICH-2 ASL14871.1     13
 Mycch_5155   Mycobacterium chubuense NBB4 AFM19841.1     13
 BTO20_30915   Mycobacterium dioxanotrophicus PH-06 ART74014.1     13
 XA26_09700   Mycobacterium fortuitum CT6 ALI24830.1     13
 XA26_60140   Mycobacterium fortuitum CT6 ALI29797.1     13
 ATO49_28450   Mycobacterium fortuitum subsp. fortuitum DSM 46621 = ATCC 6841 AMD56219.1     13
 ATO49_04625   Mycobacterium fortuitum subsp. fortuitum DSM 46621 = ATCC 6841 AMD53999.1     13
 Mflv_1032   Mycobacterium gilvum PYR-GCK ABP43515.1 A4T485   13
 Mspyr1_51560   Mycobacterium gilvum Spyr1 ADU01683.1     13
 AFA91_11345   Mycobacterium goodii X7B AKS36268.1     13
 AFA91_05335   Mycobacterium goodii X7B AKS36099.1     13
 ABG82_26960   Mycobacterium immunogenum CCUG 47286 AMT73362.1     13
 BAB75_27220   Mycobacterium immunogenum FLAC016 ANO06525.1     13
 MIP_03121   Mycobacterium indicus pranii MTCC 9506 AFS14143.1     13
 MIP_00637   Mycobacterium indicus pranii MTCC 9506 AFS12435.1     13
 LG41_01470   Mycobacterium intracellulare 1956 AIT83597.1     13
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