Glycoside Hydrolase Family 5 / Subf 13

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (583); Uniprot accession (47);
All (561) Archaea (1) Bacteria (560)
| 1 | 2 | 3 | 4 | 5 | 6 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 LuPra_01176   Acidobacteria bacterium DSM 100886 AMY07988.1     13
 ACPOL_5328   Acidobacteriaceae bacterium SBC82 AXC14578.1     13
 IMCC26256_11575   Actinobacteria bacterium IMCC26256 AKL72871.1     13
 AH4AK4_4038   Aeromonas hydrophila 4AK4 AHE51437.1     13
 AH4AK4_4042 (fragment)   Aeromonas hydrophila 4AK4 AHE51441.1     13
 B224_0634   Aeromonas media WS AHX59726.1     13
 B224_4215   Aeromonas media WS AHX62313.1     13
 A9P82_12630   Arachidicoccus sp. BS20 ANI90055.1     13
 D6B99_05415   Arachidicoccus sp. KIS59-12 AYD47100.1     13
 D6B99_09285   Arachidicoccus sp. KIS59-12 AYD47765.1     13
 AREALGSMS7_03094   Arenibacter algicola SMS7 ASO06525.1     13
 Bovatus_02440   Bacteroides ovatus ATCC 8483 ALJ47066.1     13
 BACOV975_00219   Bacteroides ovatus V975 SCV06471.1     13
 BXY_17850   Bacteroides xylanisolvens XB1A CBK66886.1 D6CXI4   13
 BXY_18020   Bacteroides xylanisolvens XB1A CBK66901.1 D6CXJ9   13
 Belba_3292   Belliella baltica DSM 15883 AFL85800.1     13
 BZG35_12345   Brevundimonas sp. LM2 AQR63518.1     13
 Acid345_0317   Candidatus Koribacter versatilis Ellin345 ABF39322.1 Q1IUX8   13
 Acid_1575   Candidatus Solibacter usitatus Ellin6076 ABJ82566.1 Q028I6   13
 C2869_07640   Catenovulum sp. CCB-QB4 AWB66312.1     13
 Cpin_1465   Chitinophaga pinensis DSM 2588 ACU58962.1 C7PRR9   13
 Cpin_2851   Chitinophaga pinensis DSM 2588 ACU60330.1 C7PLP3   13
 D4L85_30065   Chryseolinea sp. KIS68-18 AYB34569.1     13
 AL479_16580   Citrobacter amalonaticus FDAARGOS_122 AMG93994.1     13
 F384_03890   Citrobacter amalonaticus Y19 AKE58344.1     13
 A6J81_14400   Citrobacter braakii FDAARGOS_253 ARC41829.1     13
 CI104_08610   Citrobacter farmeri AUSMDU00008141 AST79138.1     13
 CFA70_13215   Citrobacter freundii 18-1 ASK01053.1     13
 AM349_19775   Citrobacter freundii AR_0022 ATX98154.1     13
 CfB38_4319   Citrobacter freundii B38 ANZ89219.1     13
 BTW28_07300   Citrobacter freundii BD APR30807.1     13
 WM46_10145   Citrobacter freundii complex sp. CFNIH2 AUO65094.1     13
 CU079_06240   Citrobacter freundii CRCB-101 ATX01247.1     13
 MC47_002550   Citrobacter freundii FDAARGOS_61 AUT94314.1     13
 ROD_08421   Citrobacter rodentium ICC168 CBG87619.1 D2TQF3   13
 CO701_19370   Citrobacter werkmanii FDAARGOS_364 ATF51125.1     13
 SAMN04515647_1864   Cohaesibacter sp. ES.047 SNY91636.1     13
 AFK63_14020   Cronobacter muytjensii ATCC 51329 ALB71678.1     13
 FH5T_02515   Draconibacterium orientale FH5 AHW58839.1     13
 FH5T_13235   Draconibacterium orientale FH5 AHW60256.1     13
 Dfer_4704   Dyadobacter fermentans DSM 18053 ACT95905.1 C6W4T1   13
 CH75_21395   Dyella jiangningensis SBZ 3-12 AHX15497.1     13
 ATSB10_27740   Dyella thiooxydans ATSB10 AND70228.1     13
 DN752_20100   Echinicola strongylocentroti MEBiC08714 AWW32257.1     13
 Echvi_2748   Echinicola vietnamensis DSM 17526 AGA78988.1     13
 AB190_13605   Enterobacter asburiae CAV1043 AKL01560.1     13
 DI57_15830   Enterobacter asburiae L1 AHW95820.1     13
 CWI88_19440   Enterobacter cancerogenus CR-Eb1 AUJ83103.1     13
 AO413_02790   Enterobacter cloacae 109 AVU18592.1     13
 Sequence 9009 from patent US 7041814   Enterobacter cloacae 15842 ABH79166.1     13
 AXJ76_02955   Enterobacter cloacae 174 AVU49119.1     13
 DPF84_06605   Enterobacter cloacae 20710 AWX01435.1     13
 BET69_02840   Enterobacter cloacae 234 AWQ41970.1     13
 CAL61_02840   Enterobacter cloacae 388 AWQ56183.1     13
 CES92_14510   Enterobacter cloacae 704SK10 ASG40093.1     13
 AM329_14010   Enterobacter cloacae AR_0002 APR43104.1     13
 AM429_06960   Enterobacter cloacae AR_0050 ASB73655.1     13
 AM432_20530   Enterobacter cloacae AR_0053 ASA06037.1     13
 AM439_13670   Enterobacter cloacae AR_0060 AVE73392.1     13
 AM444_09280   Enterobacter cloacae AR_0065 ARA26655.1     13
 AM451_16120   Enterobacter cloacae AR_0072 AVF18011.1     13
 AM452_01000   Enterobacter cloacae AR_0073 AYA10139.1     13
 AM472_07355   Enterobacter cloacae AR_0093 AVO82258.1     13
 AM383_19870   Enterobacter cloacae AR_0136 ASB85513.1     13
 AM401_14885   Enterobacter cloacae AR_0154 AWS79661.1     13
 AM409_08820   Enterobacter cloacae AR_0163 ARZ78354.1     13
 CSB67_0206   Enterobacter cloacae AR_038 AWZ97773.1     13
 ABY62_08820   Enterobacter cloacae CAV1311 AKK76755.1     13
 ABY65_23200   Enterobacter cloacae CAV1411 AKK94096.1     13
 ABY64_01800   Enterobacter cloacae CAV1668 AKK94761.1     13
 AB285_01635   Enterobacter cloacae CAV1669 AKL50130.1     13
 NF29_01505   Enterobacter cloacae colR/S AMY63444.1     13
 LI67_003710   Enterobacter cloacae complex sp. 35734 AKZ71857.1     13
 AM379_10670   Enterobacter cloacae complex sp. FDA-CDC-AR_0132 AVP00821.1     13
 AM410_04170   Enterobacter cloacae complex sp. FDA-CDC-AR_0164 AWC83668.1     13
 MC67_10310   Enterobacter cloacae complex sp. FDAARGOS_77 AVG35171.1     13
 SAMN04487932_2564   Enterobacter cloacae DG6 SMF88165.1     13
 EC05_4 (fragment)   Enterobacter cloacae EC05 APQ40336.1     13
 ECNIH2_03695   Enterobacter cloacae ECNIH2 AIE62497.1     13
 ECNIH4_20085   Enterobacter cloacae ECNIH4 AIX56415.1     13
 ECNIH5_02815   Enterobacter cloacae ECNIH5 AIX57744.1     13
 EcWSU1_00512   Enterobacter cloacae EcWSU1 AEW71952.1     13
 B1023_02750   Enterobacter cloacae FRM ASQ75482.1     13
 EC036_05410   Enterobacter cloacae GGT036 AIV28188.1     13
 AW879_20945   Enterobacter cloacae isolate MBRL1077 AMJ72269.1     13
 BFJ73_02520   Enterobacter cloacae isolate SBP-8 AOE94136.1     13
 BJM06_00528   Enterobacter cloacae M12X01451 ASQ16354.1     13
 M942_23190   Enterobacter cloacae P101 AHE71948.1     13
 B1H21_20630   Enterobacter cloacae R11 AQT90812.1     13
 B2J95_03340   Enterobacter cloacae Res2010EC27 AVL17146.1     13
 ECL_00707   Enterobacter cloacae subsp. cloacae ATCC 13047 ADF60271.1 D5CFZ0   13
 ECENHK_02905   Enterobacter cloacae subsp. cloacae ENHKU01 AFP68472.1     13
 ENC_44200   Enterobacter cloacae subsp. cloacae NCTC 9394 CBK87535.1 D6DSC2   13
 A3UG_02775   Enterobacter cloacae subsp. dissolvens SDM AFM58302.1     13
 ABT55_04705   Enterobacter cloacae UW5 AKM85925.1     13
 CSC19_3735   Enterobacter hormaechei AR432 AWF31410.1     13
 AB284_22190   Enterobacter hormaechei CAV1176 ANS19213.1     13
 AXA59_07495   Enterobacter hormaechei S13 AXO44616.1     13
 AXA51_19680   Enterobacter hormaechei S5 AXO42062.1     13
 AXA52_09020   Enterobacter hormaechei S6 AXO49927.1     13
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