Glycoside Hydrolase Family 5 / Subf 13

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (504); Uniprot accession (47);
All (482) Archaea (1) Bacteria (481)
| 1 | 2 | 3 | 4 | 5 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 Mspyr1_51560   Mycobacterium gilvum Spyr1 ADU01683.1     13
 AFA91_11345   Mycobacterium goodii X7B AKS36268.1     13
 AFA91_05335   Mycobacterium goodii X7B AKS36099.1     13
 ABG82_26960   Mycobacterium immunogenum CCUG 47286 AMT73362.1     13
 BAB75_27220   Mycobacterium immunogenum FLAC016 ANO06525.1     13
 MIP_03121   Mycobacterium indicus pranii MTCC 9506 AFS14143.1     13
 MIP_00637   Mycobacterium indicus pranii MTCC 9506 AFS12435.1     13
 LG41_01470   Mycobacterium intracellulare 1956 AIT83597.1     13
 LG41_10475   Mycobacterium intracellulare 1956 AIT85302.1     13
 OCU_02930   Mycobacterium intracellulare ATCC 13950 AFC41513.1     13
 OCU_22260   Mycobacterium intracellulare ATCC 13950 AFC43445.1     13
 CKJ61_11100   Mycobacterium intracellulare FLAC0133 ASW88194.1     13
 CKJ61_01485   Mycobacterium intracellulare FLAC0133 ASW83697.1     13
 CKJ67_01485   Mycobacterium intracellulare FLAC0181 ASW93543.1     13
 CKJ67_11025   Mycobacterium intracellulare FLAC0181 ASW98164.1     13
 OCO_02870   Mycobacterium intracellulare MOTT-02 AFC46651.1     13
 OCO_22070 (fragment)   Mycobacterium intracellulare MOTT-02 AFC48570.1     13
 B1T51_23500   Mycobacterium kansasii 10MK ARG78499.1     13
 B1T51_21860   Mycobacterium kansasii 10MK ARG78451.1     13
 B1T52_22180   Mycobacterium kansasii 11MK ARG83912.1     13
 B1T52_23890   Mycobacterium kansasii 11MK ARG83968.1     13
 B1T43_06420   Mycobacterium kansasii 1MK ARG55562.1     13
 B1T45_04795   Mycobacterium kansasii 4MK ARG64712.1     13
 B1T45_06505   Mycobacterium kansasii 4MK ARG64768.1     13
 LG40_22385   Mycobacterium kansasii 662 AIR20543.1     13
 LG40_24110   Mycobacterium kansasii 662 AIR20851.1     13
 B1T47_06335   Mycobacterium kansasii 6MK ARG72542.1     13
 B1T47_04545   Mycobacterium kansasii 6MK ARG72489.1     13
 LH54_22515   Mycobacterium kansasii 824 AIR30117.1     13
 LH54_24240   Mycobacterium kansasii 824 AIR30426.1     13
 B1T50_24350   Mycobacterium kansasii 9MK ARG96077.1     13
 B1T50_22640   Mycobacterium kansasii 9MK ARG96023.1     13
 MKAN_22605   Mycobacterium kansasii ATCC 12478 AGZ52781.1     13
 MKAN_24360   Mycobacterium kansasii ATCC 12478 AGZ53078.1     13
 MLM_0559   Mycobacterium lepraemurium Hawaii ATA27491.1     13
 MULP_01685   Mycobacterium liflandii 128FXT AGC61617.1     13
 BN939_14670   Mycobacterium marinum E11 CDM75615.1     13
 MMAR_1554   Mycobacterium marinum M ACC40006.1 B2HGM0   13
 CKJ54_01370   Mycobacterium marseillense FLAC0026 ASW88688.1     13
 CKJ54_09900   Mycobacterium marseillense FLAC0026 ASW92947.1     13
 RN08_3411   Mycobacterium microti 12 AMC60838.1     13
 D174_02715   Mycobacterium neoaurum VKM Ac-1815D AHC23565.1     13
 D174_25885   Mycobacterium neoaurum VKM Ac-1815D AIL29994.1     13
 OCQ_02880   Mycobacterium paraintracellulare AFC51801.1     13
 OCQ_21180   Mycobacterium paraintracellulare AFC53630.1     13
 MPSD_42930   Mycobacterium pseudoshottsii JCM 15466 BBA89654.1     13
 MycrhN_1746   Mycobacterium rhodesiae NBB3 AEV72358.1     13
 MSG_04789   Mycobacterium shigaense UN-152 BAX94899.1     13
 VC42_13480   Mycobacterium simiae MO323 AMP23571.1     13
 JDM601_1620   Mycobacterium sinense JDM601 AEF35620.1     13
 LI99_32720   Mycobacterium smegmatis INHR1 AIU18216.1     13
 LI99_29070   Mycobacterium smegmatis INHR1 AIU17506.1     13
 LI98_32725   Mycobacterium smegmatis INHR2 AIU24838.1     13
 LI98_29075   Mycobacterium smegmatis INHR2 AIU24129.1     13
 ERS451418_05695   Mycobacterium smegmatis NCTC8159 CKI39998.1     13
 ERS451418_06440   Mycobacterium smegmatis NCTC8159 CKI60198.1     13
 MSMEG_5877   Mycobacterium smegmatis str. MC2 155 ABK71060.1
AFP42152.1
AIU10881.1
A0R4L5   13
 MSMEG6581   Mycobacterium smegmatis str. MC2 155 ABJ96330.1
AFP42867.1
AIU11591.1
A4ZHU0   13
 CP498_16560   Mycobacterium sp. 3/86Rv ATI68747.1     13
 BCA37_29230   Mycobacterium sp. djl-10 ANW68167.1     13
 BCA37_29440   Mycobacterium sp. djl-10 ANW67136.1     13
 Mjls_5648   Mycobacterium sp. JLS ABO01412.1 A3Q8D4   13
 Mjls_5705   Mycobacterium sp. JLS ABO01469.1 A3Q8J1   13
 Mycsm_05170   Mycobacterium sp. JS623 AGB25371.1     13
 Mkms_5358   Mycobacterium sp. KMS ABL94544.1 A1UNY6   13
 Mkms_5415   Mycobacterium sp. KMS ABL94601.1 A1UP43   13
 Mmcs_5269   Mycobacterium sp. MCS ABG11370.1 Q1B164   13
 Mmcs_5326   Mycobacterium sp. MCS ABG11427.1 Q1B107   13
 W7S_01415   Mycobacterium sp. MOTT36Y AFJ33268.1     13
 W7S_10385   Mycobacterium sp. MOTT36Y AFJ35050.1     13
 BVC93_13045   Mycobacterium sp. MS1601 AQA03190.1     13
 MyAD_02650   Mycobacterium sp. NRRL B-3805 AMO04262.1     13
 MyAD_01095   Mycobacterium sp. NRRL B-3805 AMO07957.1     13
 Chelonae_p4564   Mycobacterium sp. QIA-37 AMW22315.1     13
 G155_05035   Mycobacterium sp. VKM Ac-1817D AIY45040.1
AIY45040.2
    13
 G155_29750   Mycobacterium sp. VKM Ac-1817D AIY48998.1     13
 A7U43_03860   Mycobacterium sp. YC-RL4 ANE82612.1     13
 A7U43_12960   Mycobacterium sp. YC-RL4 ANE80106.1     13
 MSTE_04960   Mycobacterium stephanolepidis NJB0901 BAY00252.1     13
 SAMEA4434518_01533   Mycobacterium terrae NCTC10856 SNV67673.1     13
 IU21_02855   Mycobacterium tuberculosis 0A005DS AIH98454.1     13
 IU23_02765   Mycobacterium tuberculosis 0A012DS AIH94858.1     13
 IU20_02765   Mycobacterium tuberculosis 0A029DS AIH91099.1     13
 IU19_02795   Mycobacterium tuberculosis 0A033DS AIH87420.1     13
 IU15_02880   Mycobacterium tuberculosis 0A036DS AIH84622.1     13
 IU22_02780   Mycobacterium tuberculosis 0A087DS AIH81001.1     13
 IU14_02750   Mycobacterium tuberculosis 0A092DS AIH77269.1     13
 IU24_02755   Mycobacterium tuberculosis 0A093DS AIH73536.1     13
 IU18_02750   Mycobacterium tuberculosis 0A094DS AIH69812.1     13
 IU17_02765   Mycobacterium tuberculosis 0A115DS AIH66481.1     13
 IU16_02805   Mycobacterium tuberculosis 0A117DS AIH63110.1     13
 IU13_02825   Mycobacterium tuberculosis 0B026XDR AIH59859.1     13
 IQ41_02720   Mycobacterium tuberculosis 0B070XDR AIH54122.1     13
 IQ38_02885   Mycobacterium tuberculosis 0B076XDR AIH51480.1     13
 IQ39_02730   Mycobacterium tuberculosis 0B123ND AIH47865.1     13
 IQ40_02795   Mycobacterium tuberculosis 0B169XDR AIH44817.1     13
 IQ48_02795   Mycobacterium tuberculosis 0B218DS AIH41459.1     13
 IQ42_02815   Mycobacterium tuberculosis 0B222DS AIH38174.1     13
 IQ47_02765   Mycobacterium tuberculosis 0B228DS AIH34715.1     13
 IQ45_02780   Mycobacterium tuberculosis 0B229DS AIH31259.1     13
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