Glycoside Hydrolase Family 5 / Subf 13

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (572); Uniprot accession (47);
All (550) Archaea (1) Bacteria (549)
| 1 | 2 | 3 | 4 | 5 | 6 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 D174_25885   Mycolicibacterium neoaurum VKM Ac-1815D AIL29994.1     13
 MycrhN_1746   Mycolicibacterium rhodesiae NBB3 AEV72358.1     13
 LI99_32720   Mycolicibacterium smegmatis INHR1 AIU18216.1     13
 LI99_29070   Mycolicibacterium smegmatis INHR1 AIU17506.1     13
 LI98_32725   Mycolicibacterium smegmatis INHR2 AIU24838.1     13
 LI98_29075   Mycolicibacterium smegmatis INHR2 AIU24129.1     13
 MSMEG_5877   Mycolicibacterium smegmatis MC2 155 ABK71060.1
AFP42152.1
AIU10881.1
A0R4L5   13
 MSMEG6581   Mycolicibacterium smegmatis MC2 155 ABJ96330.1
AFP42867.1
AIU11591.1
A4ZHU0   13
 D806_057590   Mycolicibacterium smegmatis MKD8 AWT56700.1     13
 D806_065000   Mycolicibacterium smegmatis MKD8 AWT57433.1     13
 ERS451418_05695   Mycolicibacterium smegmatis NCTC8159 CKI39998.1     13
 ERS451418_06440   Mycolicibacterium smegmatis NCTC8159 CKI60198.1     13
 MYVA_5724   Mycolicibacterium vaccae 95051 ANI42752.1     13
 Mvan_5801   Mycolicibacterium vanbaalenii PYR-1 ABM16566.1 A1THB6   13
 A8C56_06885   Niabella ginsenosidivorans BS26 ANH83758.1     13
 NIASO_06495   Niabella soli DSM 19437 AHF14902.1     13
 Niako_1305   Niastella koreensis GR20-10 AEV97676.1     13
 BES08_21405   Novosphingobium resinovorum SA1 AOR79398.1     13
 Pjdr2_1620   Paenibacillus sp. JDR-2 ACT00287.1 C6CX74   13
 BSF38_03341   Paludisphaera borealis PX4 APW61812.1     13
 CPT03_13280   Pedobacter ginsengisoli T01R-27 ATP57374.1     13
 CPT03_10370   Pedobacter ginsengisoli T01R-27 ATP56852.1     13
 Phep_0506   Pedobacter heparinus DSM 2366 ACU02730.1 C6Y0G9   13
 Phep_2643   Pedobacter heparinus DSM 2366 ACU04844.1 C6Y0D2   13
 ING2E5A_1583   Petrimonas mucosa DSM 28695 SCM57941.1     13
 H744_2c2342   Photobacterium gaetbulicola Gung47 AJR09005.1     13
 L21SP3_00676   Phycisphaerae bacterium L21-RPul-D3 AQQ08883.1     13
 STSP1_00281   Phycisphaerae bacterium ST-PulAB-D4 ARN55914.1     13
 STSP1_00355   Phycisphaerae bacterium ST-PulAB-D4 ARN55985.1     13
 VT85_25250   Planctomyces sp. SH-PL62 AMV40764.1     13
 CDO33_11090   Pseudoclostridium thermosuccinogenes DSM 5807 AUS96929.1     13
 Ping_2508   Psychromonas ingrahamii 37 ABM04229.1 A1SXL4   13
 Rahaq2_2228   Rahnella aquatilis CIP 78.65 = ATCC 33071 AEX52084.1     13
 Q7S_12120   Rahnella aquatilis HX2 AFE58647.1     13
 Rahaq_2397   Rahnella sp. Y9602 ADW74004.1     13
 AN237_05130   Raoultella ornithinolytica 18 AOO55913.1     13
 HY59_12410   Raoultella ornithinolytica A14 ANZ06140.1     13
 RORB6_05970   Raoultella ornithinolytica B6 AGJ85887.1     13
 CRN13_12615   Raoultella ornithinolytica FDAARGOS_431 ATM21184.1     13
 BK817_13595   Raoultella ornithinolytica MG APB05964.1     13
 CA210_22285   Raoultella ornithinolytica Ro24724 ASI60800.1     13
 TE10_03825   Raoultella ornithinolytica S12 AJF71233.1     13
 CRT62_12800   Raoultella planticola FDAARGOS_429 ATM05442.1     13
 CRN15_22050   Raoultella planticola FDAARGOS_430 ATM17350.1     13
 MC50_021805   Raoultella planticola FDAARGOS_64 AUU06282.1     13
 DSD31_12535   Raoultella sp. X13 AXC30245.1     13
 RHODOSMS8_01314 (fragment)   Rhodobiaceae bacterium SMS8 AWZ00856.1     13
 TH63_15600   Rufibacter sp. DG31D AKQ46723.1     13
 DC20_05970   Rufibacter tibetensis strain 1351 ALI98600.1     13
 Runsl_3697   Runella slithyformis DSM 19594 AEI50055.1     13
 AO058_17570   Salegentibacter sp. T436 APS40571.1     13
 AO058_17550   Salegentibacter sp. T436 APS40567.1     13
 2921_05   Serratia marcescens ACO52883.1 C1KH54   13
 Sinac_2792   Singulisphaera acidiphila DSM 18658 AGA27084.1     13
 CA265_01515   Sphingobacteriaceae bacterium GW460-11-11-14-LB5 ARS42851.1     13
 CA265_20575   Sphingobacteriaceae bacterium GW460-11-11-14-LB5 ARS43076.1     13
 Sph21_0597   Sphingobacterium sp. 21 ADZ77177.1     13
 SIDU_18050   Sphingobium indicum B90A APL96557.1     13
 SJA_C2-00220   Sphingobium japonicum UT26S UT26S (= NBRC 101211) BAI98385.1 D4Z7B6   13
 EP837_03619   Sphingobium sp. EP60837 ANI80003.1     13
 C1T17_05905   Sphingobium sp. SCG-1 AUW57706.1     13
 TZ53_07865   Sphingobium sp. YBL2 AJR23642.1     13
 TZ53_08230   Sphingobium sp. YBL2 AJR23707.1     13
 NX02_27800   Sphingomonas sanxanigenens DSM 19645 = NX02 AHE57143.1     13
 CVN68_10725   Sphingomonas sp. Cra20 ATY32389.1     13
 BXU08_18065   Sphingomonas sp. LM7 AQR75313.1     13
 BXU08_13420   Sphingomonas sp. LM7 AQR75896.1     13
 SKP52_01970   Sphingopyxis fribergensis Kp5.2 AJA07331.1     13
 Slin_3082   Spirosoma linguale DSM 74 ADB39093.1 D2QLE6   13
 AWR27_03035   Spirosoma montaniterrae DY10 AQG78398.1     13
 CWM47_17805   Spirosoma pollinicola HA7 AUD03519.1     13
 SD10_08375   Spirosoma radiotolerans DG5A AKD54912.1     13
 C1926_17600   Stenotrophomonas sp. ZAC14A_NAIMI4_1 AWH47624.1     13
 C1927_06565   Stenotrophomonas sp. ZAC14D1_NAIMI4_1 AWH40571.1     13
 C1929_06225   Stenotrophomonas sp. ZAC14D1_NAIMI4_6 AWH39205.1     13
 Terro_3614   Terriglobus roseus DSM 18391 AFL89828.1     13
 SAMN05444167_0165   Terriglobus roseus GAS232 SDE69376.1     13
 BMG03_04255   Thioclava nitratireducens 25B10_4 AQS49713.1     13
 Tpau_3415   Tsukamurella paurometabola DSM 20162 ADG79999.1 D5UWK0   13
 ASU32_19740   Tsukamurella sp. MH1 AUN43186.1     13
 glycoside hydrolase family GH5   uncultured bacterium AOE07480.1     13
 ORF (fragment)   uncultured bacterium ADV57624.1     13
 ORF   uncultured bacterium fosmid pJB92C9 AIF26781.1     13
 SPPYR_0451   uncultured Sphingopyxis sp. SBV31571.1     13
 VEA_002665   Vibrio antiquarius EX25 ACY50827.1 A7K363   13
 C1N51_10825   Vibrio campbellii BoB-90 AUW04157.1     13
 AL537_00790   Vibrio diabolicus FDAARGOS_105 AVF58042.1     13
 VIBNI_B1689   Vibrio nigripulchritudo SFn1 CCO61422.1     13
 RK51_006510   Vibrio parahaemolyticus 10329 AUT86476.1     13
 Vp2S01_0671   Vibrio parahaemolyticus 20130629002S01 AWG83013.1     13
 VpaChn25_2259   Vibrio parahaemolyticus CHN25 ANZ10860.1     13
 A6J30_12705   Vibrio parahaemolyticus FDAARGOS_191 ARC19275.1     13
 FORC4_2271   Vibrio parahaemolyticus FORC_004 ALM67244.1     13
 FORC23_0668   Vibrio parahaemolyticus FORC_023 AOV89211.1     13
 CO725_17680   Vibrio parahaemolyticus HA2 ATI47344.1     13
 YA91_12340   Vibrio parahaemolyticus MAVP-26 ASZ51294.1     13
 M636_09965   Vibrio parahaemolyticus O1:K33 str. CDC_K4557 AGQ97746.1     13
 M634_14360   Vibrio parahaemolyticus O1:Kuk str. FDA_R31 AGQ91574.1     13
 C7Y67_03485   Vibrio parahaemolyticus R13 AWJ77535.1     13
 C9I78_03365   Vibrio parahaemolyticus R14 AWG77906.1     13
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