Glycoside Hydrolase Family 5 / Subf 13

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (504); Uniprot accession (47);
All (482) Archaea (1) Bacteria (481)
| 1 | 2 | 3 | 4 | 5 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 AO058_17550   Salegentibacter sp. T436 APS40567.1     13
 2921_05   Serratia marcescens ACO52883.1 C1KH54   13
 Sinac_2792   Singulisphaera acidiphila DSM 18658 AGA27084.1     13
 CA265_01515   Sphingobacteriaceae bacterium GW460-11-11-14-LB5 ARS42851.1     13
 CA265_20575   Sphingobacteriaceae bacterium GW460-11-11-14-LB5 ARS43076.1     13
 Sph21_0597   Sphingobacterium sp. 21 ADZ77177.1     13
 SIDU_18050   Sphingobium indicum B90A APL96557.1     13
 SJA_C2-00220   Sphingobium japonicum UT26S UT26S (= NBRC 101211) BAI98385.1 D4Z7B6   13
 EP837_03619   Sphingobium sp. EP60837 ANI80003.1     13
 TZ53_07865   Sphingobium sp. YBL2 AJR23642.1     13
 TZ53_08230   Sphingobium sp. YBL2 AJR23707.1     13
 NX02_27800   Sphingomonas sanxanigenens DSM 19645 = NX02 AHE57143.1     13
 BXU08_18065   Sphingomonas sp. LM7 AQR75313.1     13
 BXU08_13420   Sphingomonas sp. LM7 AQR75896.1     13
 SKP52_01970   Sphingopyxis fribergensis Kp5.2 AJA07331.1     13
 Slin_3082   Spirosoma linguale DSM 74 ADB39093.1 D2QLE6   13
 AWR27_03035   Spirosoma montaniterrae DY10 AQG78398.1     13
 SD10_08375   Spirosoma radiotolerans DG5A AKD54912.1     13
 Terro_3614   Terriglobus roseus DSM 18391 AFL89828.1     13
 SAMN05444167_0165   Terriglobus roseus GAS232 SDE69376.1     13
 BMG03_04255   Thioclava nitratireducens 25B10_4 AQS49713.1     13
 Tpau_3415   Tsukamurella paurometabola DSM 20162 ADG79999.1 D5UWK0   13
 glycoside hydrolase family GH5   uncultured bacterium AOE07480.1     13
 ORF (fragment)   uncultured bacterium ADV57624.1     13
 ORF   uncultured bacterium fosmid pJB92C9 AIF26781.1     13
 SPPYR_0451   uncultured Sphingopyxis sp. SBV31571.1     13
 VEA_002665   Vibrio antiquarius EX25 ACY50827.1 A7K363   13
 VIBNI_B1689   Vibrio nigripulchritudo SFn1 CCO61422.1     13
 VpaChn25_2259   Vibrio parahaemolyticus CHN25 ANZ10860.1     13
 A6J30_12705   Vibrio parahaemolyticus FDAARGOS_191 ARC19275.1     13
 FORC4_2271   Vibrio parahaemolyticus FORC_004 ALM67244.1     13
 FORC23_0668   Vibrio parahaemolyticus FORC_023 AOV89211.1     13
 CO725_17680   Vibrio parahaemolyticus HA2 ATI47344.1     13
 YA91_12340   Vibrio parahaemolyticus MAVP-26 ASZ51294.1     13
 M636_09965   Vibrio parahaemolyticus O1:K33 str. CDC_K4557 AGQ97746.1     13
 M634_14360   Vibrio parahaemolyticus O1:Kuk str. FDA_R31 AGQ91574.1     13
 VP2395   Vibrio parahaemolyticus RIMD 2210633 O3:K6 BAC60658.1
NP_798774.1
    13
 BSZ05_09880   Vibrio shilonii QT6D1 ASI90066.1     13
 ORF   Vibrio tasmaniensis FF_112 AKN38526.1     13
 VV93_v1c23520   Vibrio vulnificus 93U204 AIL71430.1     13
 FORC37_2188   Vibrio vulnificus FORC_037 ASC57882.1     13
 AW19_2483   Yersinia frederiksenii Y225 AJI87395.1     13
 CH53_3461   Yersinia intermedia Y228 AJJ21305.1     13
 DJ57_73   Yersinia kristensenii ATCC 33639 AIN17485.1     13
 CH54_3304   Yersinia kristensenii Y231 AJJ35271.1     13
 M486_2154   Yersinia pestis 1045 AKT02463.1     13
 M478_2212   Yersinia pestis 2944 AKS63812.1     13
 M477_3237   Yersinia pestis 790 AKS84007.1     13
 A1122_01260   Yersinia pestis A1122 AEL70935.1
AJJ73576.1
    13
 YPA_3393   Yersinia pestis Antiqua ABG15355.1
AJJ79602.1
Q1C2G7   13
 YPC_0794   Yersinia pestis biovar Medievalis str. Harbin 35 ADV97486.1     13
 YP3444   Yersinia pestis biovar Microtus str. 91001 AAS63604.1
NP_994727.1
    13
 BAY22_02465   Yersinia pestis Cadman ANW12914.1     13
 AK38_1817   Yersinia pestis CO92 AJJ90027.1     13
 YPD4_0658   Yersinia pestis D106004 ACY57567.1 D0JFL3   13
 YPD8_0658 (fragment)   Yersinia pestis D182038 ACY61348.1 D0JQ35   13
 CH61_3449   Yersinia pestis Dodson AJJ32882.1     13
 CH46_162   Yersinia pestis El Dorado AJJ16012.1     13
 CH55_3543   Yersinia pestis Harbin35 AJK07828.1     13
 CH62_3904   Yersinia pestis Java9 AJJ39389.1     13
 Y3438 (probable fragment)   Yersinia pestis KIM10+ AAM86987.1
NP_670736.1
    13
 CH44_2037   Yersinia pestis KIM5 AKB89791.1     13
 CH45_128   Yersinia pestis Nairobi AJK20368.1     13
 YPN_3196   Yersinia pestis Nepal516 ABG19523.1 Q1CEQ7   13
 CH63_1298   Yersinia pestis Nicholisk 41 AJJ45062.1     13
 CH59_1109   Yersinia pestis PBM19 AJI90819.1     13
 BZ15_2819   Yersinia pestis Shasta AJJ50222.1     13
 CH60_3341   Yersinia pestis str. Pestoides B AJK12567.1     13
 BZ23_2830   Yersinia pseudotuberculosis 1 AJJ71713.1     13
 DJ40_3168   Yersinia pseudotuberculosis ATCC 6904 AIN15627.1     13
 BZ20_2845   Yersinia pseudotuberculosis EP2/+ AJJ08646.1     13
 YpsIP31758_0708   Yersinia pseudotuberculosis IP 31758 ABS49253.1 A7FEL9   13
 YPTB3269   Yersinia pseudotuberculosis IP 32953 CAH22507.1     13
 BZ17_3341   Yersinia pseudotuberculosis IP 32953 AJJ55811.1     13
 BZ21_2549   Yersinia pseudotuberculosis MD67 AJJ02299.1     13
 YPTS_3405   Yersinia pseudotuberculosis PB1/+ ACC90360.1
AJJ66627.1
B2K1I7   13
 BZ19_2675   Yersinia pseudotuberculosis str. PA3606 AJK15186.1     13
 YPK_0780   Yersinia pseudotuberculosis YPIII ACA67081.1
AJJ57863.1
B1JMZ8   13
 CH64_1914   Yersinia rohdei YRA AJJ09410.1     13
 BF17_03365   Yersinia similis CCUG 52882 AHK18490.1     13
 ZPR_4337   Zunongwangia profunda SM-A87 ADF54639.1 D5BB99   13
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