Activities in Family	Glucomannan-specific endo-β-1,4-glucanase (EC 3.2.1.-); Xyloglucan-specific endo-β-1,4-glucanase / endo-xyloglucanase (EC 3.2.1.151); Endo-β-1,4-glucanase (EC 3.2.1.4);
Mechanism	Inverting e
3D Structure Status	6-stranded β-barrel
Catalytic Nucleophile/Base	Asp (experimental)
Catalytic Proton Donor	Asp (experimental).
Note	formerly known as cellulase family K; distantly related to plant expansins
External resources	CAZypedia; Expansin; PROSITE;
Statistics	GenBank accession (692); Uniprot accession (102); PDB accession (34); 3D entries (10); cryst (0)

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Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
9683		Talaromyces marneffei ATCC 18224 (Talma1_2)				2
10585		Talaromyces marneffei ATCC 18224 (Talma1_2)				2
TRUGW13939_01356		Talaromyces rugulosus W13939	QKX54271.1			2
TRUGW13939_09374 (fragment)		Talaromyces rugulosus W13939	QKX62215.1			3
10040		Talaromyces stipitatus ATCC 10500 (Talst1_2)				2
11120		Talaromyces stipitatus ATCC 10500 (Talst1_2)				2
76567		Teratosphaeria nubilosa CBS 116005 v1 (Ternu1)				1
355042		Teratosphaeria nubilosa CBS 116005 v1 (Ternu1)
460159		Thamnidium elegans v1.0 (Thaele1)				1
348692		Thamnidium elegans v1.0 (Thaele1)				1
654848		Thanatephorus cucumeris PT424 v1.0 (Thacu1)				4
578674		Thanatephorus cucumeris PT424 v1.0 (Thacu1)				1
1033097		Thelephora terrestris UH-Tt-Lm1 v1.0 (Theter1)				4
GH45 (fragment)		Thermoascus aurantiacus CBS 891.70	CDF76463.1			1
GH45 (fragment)		Thermochaetoides thermophila CBS 180.67	CDF76461.1			1
endo-?-1,4-glucanase (Cbh45-1)	3.2.1.4	Thermochaetoides thermophila CT2	AGY80100.1	V9PD44		1
Cbh45-2		Thermochaetoides thermophila CT2	AGY80101.1			1
GH45 (fragment)		Thermomucor indicae-seudaticae CBS 104.75	CDF76459.1			1
unnamed protein product (fragment)		Thermomyces verrucosus	CAL49899.1			1
endo-β-1,4-glucanase (MtGH45; MYCTH_76901)	3.2.1.4	Thermothelomyces thermophilus ATCC 42464	AEO54078.1	G2Q0Y0		1
endo-β-1,4-glucanase (THITE_2110957)	3.2.1.4	Thermothielavioides terrestris NRRL 8126	AEO64667.1	G2QVH7	5GLX[A] 5GLY[A] 5GM9[A]	1
THITE_2143588		Thermothielavioides terrestris NRRL 8126	AEO65930.1			1
β-1_4-endoglucanase (Cel45)	3.2.1.4	Thielavia arenaria XZ7	APQ40634.1	A0A2U7M673		1
endoglucanase		Thielavia terrestris	CAH03187.1 AAE27824.1 AAE40642.1 AAY00849.1 ABU25926.1			1
259301		Tilletiaria anomala UBC 951 v1 (Tilan2)				4
191418		Tolypocladium inflatum NRRL 8044 (Tolinf1)
4573		Tolypocladium paradoxum NRBC 100945 (Tolpa1)				1
610700		Tothia fuscella CBS 130266 v1 (Totfu1)				1
52878		Tothia fuscella CBS 130266 v1 (Totfu1)				3
897180		Trametes betulina CIRM-BRFM 1801 (Trabet1)				1
800077		Trametes betulina CIRM-BRFM 1801 (Trabet1)				4
344622		Trametes betulina CIRM-BRFM 1801 (Trabet1)				3
1383135		Trametes gibbosa CIRM-BRFM 1770 v1.0 (Tragib1)				4
1310615		Trametes gibbosa CIRM-BRFM 1770 v1.0 (Tragib1)				3
1050485		Trametes ljubarskyi (Tralj1)				3
962047		Trametes ljubarskyi (Tralj1)				4
1037439		Trametes ljubarskyi (Tralj1)				1
965787		Trametes maxima CIRM-BRFM 1813 v1.0 (Tramax1)				4
1082188		Trametes maxima CIRM-BRFM 1813 v1.0 (Tramax1)				1
353340		Trametes maxima CIRM-BRFM 1813 v1.0 (Tramax1)				3
929271		Trametes meyenii CIRM-BRFM 1810 (Tramey1)				3
911448		Trametes meyenii CIRM-BRFM 1810 (Tramey1)				4
1128397		Trametes polyzona CIRM-BRFM 1798 (Trapol1)				1
254353		Trametes polyzona CIRM-BRFM 1798 (Trapol1)				4
1161525		Trametes polyzona CIRM-BRFM 1798 (Trapol1)				3
168018		Trametes versicolor FP-101664 SS1 (Trave1)				3
24300		Trametes versicolor FP-101664 SS1 (Trave1)				1
26658		Trametes versicolor FP-101664 SS1 (Trave1)				4
507210		Trematosphaeria pertusa CBS 122368 v1 (Trepe1)				1
404977		Trematosphaeria pertusa CBS 122368 v1 (Trepe1)				1
531250		Trematosphaeria pertusa CBS 122368 v1 (Trepe1)				1
492755		Trematosphaeria pertusa CBS 122368 v1 (Trepe1)				1
436774		Trematosphaeria pertusa CBS 122368 v1 (Trepe1)				1
527351		Trematosphaeria pertusa CBS 122368 v1 (Trepe1)				1
381388		Thielavia antarctica CBS 123565 v1 (Thian1)				1
4993		Trichocladium griseum var. thermoidea UFV (Humgr1)				1
3639		Trichocladium griseum var. thermoidea UFV (Humgr1)				1
1524		Trichoderma arundinaceum IBT 40837 (Triaru1)				2
117		Trichoderma arundinaceum IBT 40837 (Triaru1)				1
168884		Trichoderma asperelloides T203 v1.0 (Triasper1)				2
471617		Trichoderma asperellum TR356 v1.0 (Triasp1)				2
TrA_004572 (Egl5)		Trichoderma asperellum FT101	UKZ88838.1			2
92665		Trichoderma atrobrunneum ITEM 908 (Triatrob1)				2
86758		Trichoderma atrobrunneum ITEM 908 (Triatrob1)				1
TrAtP1_005190		Trichoderma atroviride P1	UKZ63968.1			2
297095		Trichoderma atroviride v2.0 (Triat2)				2
116231		Trichoderma brevicompactum IBT40841 (Tribre1)				2
125477		Trichoderma brevicompactum IBT40841 (Tribre1)				1
1127360		Trichoderma citrinoviride v4 (Trici4)				2
434		Trichoderma gamsii T6085 (Trigam1)				2
3859		Trichoderma gamsii T6085 (Trigam1)				2
6700		Trichoderma guizhouense NJAU 4742 (Trigui1)				1
303		Trichoderma guizhouense NJAU 4742 (Trigui1)				2
423240		Trichoderma harzianum TR274 v1.0 (Trihar1)				1
813797		Trichoderma harzianum TR274 v1.0 (Trihar1)				2
225444		Trichoderma harzianum TR274 v1.0 (Trihar1)				2
66627		Trichoderma longibrachiatum ATCC 18648 v3 (Trilo3)				2
4354		Trichoderma parareesei CBS 125925 (Tripar1)				2
110458		Trichoderma pleuroti TPhu1 (Triple1)				1
110076		Trichoderma pleuroti TPhu1 (Triple1)				2
endoglucanase V (EGV) (Cel45A)	3.2.1.4	Trichoderma reesei	CAA83846.1	P43317		2
8744		Trichoderma reesei CBS999.97 MAT1-1 (TrireMAT11_1)				2
8733		Trichoderma reesei CBS999.97 MAT1-2 (TrireMAT12_1)				2
116683		Trichoderma reesei QM6a (Trire_Chr)				2
25940		Trichoderma reesei RUT C-30 v1 (TrireRUTC30_1)				2
endoglucanase		Trichoderma reesei SJVTR	AHK23046.1			2
49976		Trichoderma reesei (Trire2)				2
H0G86_009747		Trichoderma simmonsii GH-Sj1	QYT02752.1			1
H0G86_007156 (fragment)		Trichoderma simmonsii GH-Sj1	QYT00049.1			2
H0G86_012471		Trichoderma simmonsii GH-Sj1	QYT05581.1			2
TrVFT333_006787 (fragment)		Trichoderma virens FT-333	UKZ79036.1			1
TrVFT333_006398 (Egl5_2)		Trichoderma virens FT-333	UKZ78652.1			2
TrVFT333_006030 (Egl5_1) (fragment)		Trichoderma virens FT-333	UKZ78294.1			2
TrVGV298_006639 (Egl5_2)		Trichoderma virens Gv29-8	UKZ52852.1			2
TrVGV298_006262 (Egl5_1)		Trichoderma virens Gv29-8	UKZ52485.1			2
58412		Trichoderma virens Gv29-8 v2.0 (TriviGv29_8_2)				2
59335		Trichoderma virens Gv29-8 v2.0 (TriviGv29_8_2)				2
endoglucanase V (EGV)	3.2.1.4	Trichoderma viride AS 3.3711	AAQ21385.1	Q7Z7X0		2
1251492		Tricholoma matsutake v3 (Trima3)				4
883512		Trichophaea hybrida UTF0779 v1.0 (Trihyb1)				1
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