Glycoside Hydrolase Family 45

Activities in Familyendoglucanase (EC 3.2.1.4); xyloglucan-specific endo-β-1,4-glucanase / endo-xyloglucanase (EC 3.2.1.151); endo-β-1,4-mannanase (EC 3.2.1.78)
Mechanism Inverting
3D Structure Status6-stranded β-barrel
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorAsp (experimental).
Noteformerly known as cellulase family K; distantly related to plant expansins
External resourcesCAZypedia; Expansin; PROSITE;
Statistics GenBank accession (611); Uniprot accession (94); PDB accession (33); 3D entries (9); cryst (0)
Bacteria
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 endo-β-1,4-glucanase B / 45A (CelB;EGB;CJA_0374) (Cel45A) 3.2.1.4 pubmed
Cellvibrio japonicus Ueda107 ACE82688.1
CAA36844.1
B3PI35
P18126
 
 endo-β-1,4-glucanase (F45;Fisuc_1933;FSU_2443) 3.2.1.4 pubmed
Fibrobacter succinogenes subsp. succinogenes S85 ACX75523.1
ADL26053.1
C9RIQ2  
 endoglucanase B (GnuB) 3.2.1.4 pubmed
uncultured bacterium AAP49340.1 Q6XR86  
Eukaryota
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 cellulase (Eng-2;ArENG2) 3.2.1.4 pubmed
Adineta ricciae AKC91346.1 A0A0E3Z7U1  
 endo-β-1,4-glucanase (EG27I) 3.2.1.4 pubmed
Ampullaria crossean ABR92637.1 A7KME9  
 endo-β-1,4-glucanase (EG27II) 3.2.1.4 pubmed
Ampullaria crossean ABR92638.1 A7KMF0 5XBU[A]
5XBX[A]
5XC4[A]
5XC8[A]
5XC9[A]
5XCA[A]
 cellulase 45A (AmCel-45A) 3.2.1.4 pubmed
Anoplophora chinensis AFN89565.1 K4GMG5  
 endo-β-1,4-glucanase (GABY01019707.1) 3.2.1.4 pubmed
Anthonomus grandis      
 cellulase 21K (AkEG21;AkEG22) 3.2.1.4 pubmed
Aplysia kurodai BAP19116.1 A0A077JGH0  
 cellulase I (Ag-EGaseI) 3.2.1.4 pubmed
Apriona germari AAN78326.1
AAU44973.1
Q5XQD1
Q8I815
 
 endoglucanase II (Ag-EGaseII) 3.2.1.4 pubmed
Apriona germari AAR22385.1 Q6SS52  
 glycoside hydrolase family 45 (Gh45-1) 3.2.1.4 pubmed
Apriona japonica AHI15752.1 X2D5K6  
 glycoside hydrolase family 45 (Gh45-2) 3.2.1.4 pubmed
Apriona japonica AHI15753.1 X2D6C4  
 cellulase I (Bh-EGaseI) 3.2.1.4 pubmed
Batocera horsfieldi AKH90729.1 A0A0F7NSK2  
 endoglucanase (Eng2;Bx-eng-2) 3.2.1.4 pubmed
Bursaphelenchus xylophilus KA4 BAD34544.1
BAD34547.1
Q6BCL7  
 endoglucanase (Eng3;Bx-Eng-3) 3.2.1.4 pubmed
Bursaphelenchus xylophilus KA4 BAD34548.1
BAD34545.1
Q6BCL3  
 endoglucanase (Eng1;Bx-Eng-1) 3.2.1.4 pubmed
Bursaphelenchus xylophilus KA4 BAD34546.1
AFD53037.1
AFD53038.1
AFD53040.1
AFD53041.1
AFD53042.1
AFD53045.1
AFD53047.1
AFD53048.1
AFD53049.1
AFD53052.1
AFD53053.1
AFD53054.1
AFD53058.1
AFD53061.1
AFD53062.1
BAD34543.1
K4F7Y8
K4FA32
Q6BCM1
Q6BCN0
 
 endo-β-1,4-glucanase; (gluco)mannanase (CTR3) 3.2.1.4
3.2.1.78
pubmed
pubmed
Chrysomela tremula QCF40862.1 A0A4D6Q5X5  
 endo-β-1,4-glucanase; (gluco)mannanase (CTR1) 3.2.1.4
3.2.1.78
pubmed
pubmed
Chrysomela tremulae ADU33285.1 E7CIS3  
 xyloglucan hydrolase; (gluco)mannanase (CTR2) 3.2.1.151
3.2.1.78
pubmed
pubmed
Chrysomela tremulae ADU33286.1 E7CIS4  
 endoglucanase (EG5;EG V) (Cel45A) 3.2.1.4 pubmed
Chrysosporium lucknowense C1 AAQ38150.1
ACH15008.1
   
 endo-β-1,4-glucanase (CjCel45A) (Cel45A) 3.2.1.4 pubmed
Corbicula japonica BAH23793.1 B9X0W0  
 endo-β-1,4-glucanase 3.2.1.4 pubmed
Crinipellis scabella AAY00851.1    
 endo-β-1,4-glucanase (Cel;CaCel) 3.2.1.4 pubmed
Cryptopygus antarcticus ACV50414.1
ACV50415.1
D3GDK4 5H4U[A,B,C]
 xyloglucan hydrolase (DVI6) 3.2.1.151 pubmed
Diabrotica virgifera virgifera QCF40872.1 A0A4D6Q5Y3  
 xyloglucan hydrolase (DVI5) 3.2.1.151 pubmed
Diabrotica virgifera virgifera QCF40871.1 A0A4D6Q4A9  
 endo-β-1,4-glucanase (DVI2) 3.2.1.4 pubmed
Diabrotica virgifera virgifera QCF40868.1 A0A4D6Q326  
 endo-β-1,4-glucanase; (gluco)mannanase (DVI9) 3.2.1.4
3.2.1.78
pubmed
pubmed
Diabrotica virgifera virgifera QCF40875.1 A0A4D6Q7U5  
 endo-β-1,4-glucanase; (gluco)mannanase (DVI10) 3.2.1.4
3.2.1.78
pubmed
pubmed
Diabrotica virgifera virgifera QCF40876.1 A0A4D6Q3T6  
 endo-β-1,4-glucanase; (gluco)mannanase (DVI8) 3.2.1.4
3.2.1.78
pubmed
pubmed
Diabrotica virgifera virgifera QCF40874.1 A0A4D6Q2Y3  
 endo-β-1,4-glucanase; (gluco)mannanase (DVI11) 3.2.1.4
3.2.1.78
pubmed
pubmed
Diabrotica virgifera virgifera QCF40877.1 A0A4D6Q371  
 endo-β-1,4-glucanase (DVI1;DvvENGaseI) 3.2.1.4 pubmed
Diabrotica virgifera virgifera AFI56547.1 I1VZE8  
 endoglucanase (FpCel45A) (Cel45A) 3.2.1.4   Fomitopsis palustris FFPRI 0507 BAI58030.1
AVV62522.1
BAI58029.1
   
 endo-β-1,4-glucanase (Gh45-2) 3.2.1.4 pubmed
Gastrophysa viridula AZH23718.1    
 xyloglucan-specific endo-β-1,4-glucanase / endo-xyloglucanase (Gh45-1) 3.2.1.151 pubmed
Gastrophysa viridula ADU33334.1    
 endo-β-1,4-glucanase (GLOTRDRAFT_59933) 3.2.1.4 pubmed
Gloeophyllum trabeum ATCC 11539 EPQ56593.1    
 endo-β-1,4-glucanase (Egl3) 3.2.1.4 pubmed
Humicola grisea var. thermoidea BAA74956.1
AAE55435.1
AAN19009.1
O93782
P43316
1HD5[A]
 endo-β-1,4-glucanase IV (Egl4;EGIV) 3.2.1.4 pubmed
Humicola grisea var. thermoidea BAA74957.1 O93783  
 endo-β-1,4-glucanase V (EGV;EG V;NCE5) (Cel45A) 3.2.1.4 pubmed
Humicola insolens DSM 1800 CAB42307.1
AAE16508.1
AAN23440.1
AAO30277.1
AAO30279.1
AAX00991.1
AAY74558.1
ABA35703.1
ABN29330.1
CAA01574.1
CAA01681.1
CAA01683.1
CAA01696.1
CAA01698.1
CAJ21530.1
P43316 2ENG[A]
3ENG[A]
4ENG[A]
 endo-β-1,4-glucanase (PAS_chr4_0643) (Cel45A) 3.2.1.4 pubmed
Komagataella phaffii GS115 CAY71902.1
AOA69625.1
C4R8H7  
 endo-β-1,4-glucanase (DIV10) 3.2.1.4 pubmed
Leptinotarsa decemlineata QCF40865.1 A0A4D6Q7T7  
 xyloglucan hydrolase (DIV11) 3.2.1.151 pubmed
Leptinotarsa decemlineata QCF40866.1 A0A4D6Q3S7  
 endo-β-1,4-glucanase (LDE2) 3.2.1.4
3.2.1.78
pubmed
pubmed
Leptinotarsa decemlineata ADU33346.1 E7CIY4  
 endo-β-1,4-glucanase; (gluco)mannanase (LDE3) 3.2.1.4
3.2.1.78
pubmed
pubmed
Leptinotarsa decemlineata ADU33347.1 E7CIY5  
 endo-β-1,4-glucanase; xyloglucan hydrolase (LDE5) 3.2.1.151
3.2.1.4
pubmed
pubmed
Leptinotarsa decemlineata ADU33349.1 E7CIY7  
 endo-β-1,4-glucanase (LDE6) 3.2.1.4 pubmed
Leptinotarsa decemlineata ADU33350.1 E7CIY8  
 endo-β-1,4-glucanase; (gluco)mannanase (LDE7) 3.2.1.4
3.2.1.78
pubmed
pubmed
Leptinotarsa decemlineata ADU33351.1 E7CIY9  
 endo-β-1,4-glucanase (Cel45A) 3.2.1.4 pubmed
Macrophomina phaseolina AAY00850.1
CAL49897.1
   
 endoglucanase (Fm1;HG 67-5) 3.2.1.4 pubmed
Mastotermes darwiniensis hindgut symbiont sp. CAD39197.1 Q7YZU0  
 endoglucanase (Fm3) 3.2.1.4 pubmed
Mastotermes darwiniensis hindgut symbiont sp. CAD39199.1 Q7YZT8  
 endoglucanase (Fm4) 3.2.1.4 pubmed
Mastotermes darwiniensis hindgut symbiont sp. CAD39200.1 Q7YZT7  
 endoglucanase (Fm2) 3.2.1.4 pubmed
Mastotermes darwiniensis hindgut symbiont sp. CAD39198.1 Q7YZT9  
 endo-β-1,4-glucanase (MaCel45A) (Cel45A) 3.2.1.4 doi
Melanocarpus albomyces CAD56665.1
AAU96162.1
QCO31627.1
Q8J0K8 1L8F[A]
1OA7[A]
1OA9[A]
 endo-β-1,4-glucanase (Mce1) 3.2.1.4 pubmed
Mucor circinelloides FERM P-17446 BAD95808.1
ABA29991.1
ACK18401.1
Q53VB3  
 endo-β-1,4-glucanase (Mce2) 3.2.1.4 pubmed
Mucor circinelloides FERM P-17446 BAD95809.1
ABA29992.1
ACK18402.1
Q53VB2  
 endoglucanase (Eg) 3.2.1.4 pubmed
Mytilus edulis CAC59695.1
CAC59694.1
P82186
Q95P02
1WC2[A]
 endoglucanase (NcCel45A;NCU05121.1) (Cel45A) 3.2.1.4 pubmed
pubmed
Neurospora crassa OR74A CAD70529.1
EAA27871.1
XP_324478.1
Q1K5M0
Q872Q1
6MVI[A]
6MVJ[A]
 endoglucanase V / 45A (EG V;PdCel45A) (Cel45A) 3.2.1.4 pubmed
Penicillium decumbens 114-2 ACF33814.1 B5AKD1  
 endo-β-1,4-glucanase (EG) 3.2.1.4 pubmed
Phaedon cochleariae CAA76931.1 O97401  
 endo-β-1,4-glucanase (PCO1) 3.2.1.4 pubmed
Phaedon cochleariae CCJ09450.1 K4QDH6  
 xyloglucan hydrolase (PCO7) 3.2.1.151 pubmed
Phaedon cochleariae CCJ09455.1 K4QDH7  
 endo-β-1,4-glucanase; (gluco)mannanase (PCO3) 3.2.1.4
3.2.1.78
pubmed
pubmed
Phaedon cochleariae CCJ09451.1 K4QDG4  
 endo-β-1,4-glucanase; (gluco)mannanase (PCO4) 3.2.1.4
3.2.1.78
pubmed
pubmed
Phaedon cochleariae CCJ09452.1 K7DWA1  
 endo-β-1,4-glucanase; (gluco)mannanase (PCO5) 3.2.1.4
3.2.1.78
pubmed
pubmed
Phaedon cochleariae CCJ09453.1 K7DW99  
 endo-β-1,4-glucanase; (gluco)mannanase (PCO6) 3.2.1.4
3.2.1.78
pubmed
pubmed
Phaedon cochleariae CCJ09454.1 K7DWA7  
 cellulase (Ghf45eg-1) (fragment) 3.2.1.4 pubmed
Phaeosphaeria sp. LH21 AGU16531.1 T1WGL7  
 cellulase (Ghf45eg-2) 3.2.1.4 pubmed
Phaeosphaeria sp. LH21 AGU16532.1 T1WFT4  
 endoglucanase V (EGV;PcCel45A) (Cel45A) 3.2.1.4 pubmed
Phanerochaete chrysosporium K-3 BAG68300.1
AEK06231.1
B3Y002
G0ZPJ6
3X2G[A]
3X2H[A]
3X2I[A]
3X2J[A]
3X2K[A]
3X2L[A]
3X2M[A]
3X2N[A]
3X2O[A]
3X2P[A]
4ZM7[A]
5KJO[A]
5KJQ[A]
 endo-β-1,4-glucanase (Pce1) 3.2.1.4 pubmed
Phycomyces nitens FERM P-17447 BAD77808.1
ABA29993.1
ACK18403.1
Q5R230  
 endoglucanase 45A (Cel45A) 3.2.1.4 pubmed
Piromyces sp. equi CAB92325.1 Q9P868  
 endoglucanase (RsSym45eg1;RsSymEG2;SM2038B84) 3.2.1.4 pubmed
Reticulitermes speratus hindgut protist 130484 BAA98041.1
BAF57324.1
BAG71490.1
A4UWR4
Q9JH92
 
 RrCel45 3.2.1.4 doi
Rhizophlyctis rosea AWL24828.1 A0A2U8LMQ2  
 endo-β-1,4-glucanase (Rce1;RCE I) 3.2.1.4 pubmed
Rhizopus arrhizus FERM BP-6889 BAC53956.1
ABA29988.1
ACK18398.1
Q8J1L2  
 endo-β-1,4-glucanase (Rce2; RCE II) 3.2.1.4 pubmed
Rhizopus arrhizus FERM BP-6889 BAC53987.1
ABA29990.1
ACK18400.1
Q8J1L1  
 endo-β-1,4-glucanase (Rce3; RCE III) 3.2.1.4 pubmed
Rhizopus arrhizus FERM BP-6889 BAC53988.1
ABA29989.1
ACK18399.1
Q8J1L0  
 endo-β-1,4-glucanase (EG2) 3.2.1.4 pubmed
Rhizopus reflexus TP-02 AFQ94052.1    
 sscle_01g005720 3.2.1.4 pubmed
Sclerotinia sclerotiorum 1980 UF-70 APA05802.1 A0A1D9PTE7  
 endoglucanase I (EgI) 3.2.1.4 pubmed
Scopulariopsis brevicaulis TOF-1212   Q7M4T4  
 endo-β-1,4-glucanase (SOR1) 3.2.1.4 pubmed
Sitophilus oryzae ADU33246.1 E7CIN4  
 endo-β-1,4-glucanase(SOR2) 3.2.1.4 pubmed
Sitophilus oryzae ADU33247.1 E7CIN5  
 xyloglucan hydrolase (SOR3) 3.2.1.151 pubmed
Sitophilus oryzae ADU33248.1 E7CIN6  
 xyloglucan hydrolase (SOR4) 3.2.1.151 pubmed
Sitophilus oryzae ADU33249.1 E7CIN7  
 xyloglucan hydrolase (SOR5) 3.2.1.151 pubmed
Sitophilus oryzae ADU33250.1 E7CIN8  
 endo-β-1,4-glucanase (Stce1) 3.2.1.4 pubmed
Staphylotrichum coccosporum IFO 31817 BAG69187.1 B5BNY1  
 endoglucanase (CBH I) 3.2.1.4 pubmed
Syncephalastrum racemosum BCC18080 ABU49185.2 A7UGD9  
 endo-?-1,4-glucanase (Cbh45-1) 3.2.1.4 pubmed
Thermochaetoides thermophila CT2 AGY80100.1    
 endo-β-1,4-glucanase (MYCTH_76901) 3.2.1.4 pubmed
Thermothelomyces thermophilus ATCC 42464 AEO54078.1    
 endo-β-1,4-glucanase (THITE_2110957) 3.2.1.4 pubmed
Thermothielavioides terrestris NRRL 8126 AEO64667.1 G2QVH7 5GLX[A]
5GLY[A]
5GM9[A]
 β-1_4-endoglucanase (Cel45) 3.2.1.4 pubmed
Thielavia arenaria XZ7 APQ40634.1    
 endoglucanase V (EGV) (Cel45A) 3.2.1.4 pubmed
Trichoderma reesei CAA83846.1 P43317  
 endoglucanase V (EGV) 3.2.1.4 pubmed
Trichoderma viride AS 3.3711 AAQ21385.1 Q7Z7X0  
 NT0285A89 3.2.1.4 pubmed
uncultured symbiotic protist of Hodotermopsis sjoestedti BAF57356.1 A4UWU6  
 SM2765A61 3.2.1.4 pubmed
uncultured symbiotic protist of Mastotermes darwiniensis BAF57450.1 A4UX40  
 SM2760A28 3.2.1.4 pubmed
uncultured symbiotic protist of Mastotermes darwiniensis BAF57443.1 A4UX33  
 SM2030A92 3.2.1.4 pubmed
uncultured symbiotic protist of Reticulitermes speratus BAF57323.1 A4UWR3  
 SM2042A70 3.2.1.4 pubmed
uncultured symbiotic protist of Reticulitermes speratus BAF57325.1 A4UWR5  
 endo-1,4-glucanase 1 (Egl1) 3.2.1.4 pubmed
Ustilago maydis AAB36147.1 P54424  
Top


Last update: 2022-06-09 © Copyright 1998-2022
AFMB - CNRS - Université d'Aix-Marseille