Glycoside Hydrolase Family 45

Activities in Family	Glucomannan-specific endo-β-1,4-glucanase (EC 3.2.1.-); Xyloglucan-specific endo-β-1,4-glucanase / endo-xyloglucanase (EC 3.2.1.151); Endo-β-1,4-glucanase (EC 3.2.1.4);
Mechanism	Inverting e
3D Structure Status	6-stranded β-barrel
Catalytic Nucleophile/Base	Asp (experimental)
Catalytic Proton Donor	Asp (experimental).
Note	formerly known as cellulase family K; distantly related to plant expansins
External resources	CAZypedia; Expansin; PROSITE;
Statistics	GenBank accession (692); Uniprot accession (102); PDB accession (34); 3D entries (10); cryst (0)

Summary

Download GH45 (2249) Taxonomic display Structure (10) Characterized (97)

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Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
xyloglucan hydrolase (PCO7)	3.2.1.151	Phaedon cochleariae	CCJ09455.1	K4QDH7		1
endo-β-1,4-glucanase; (gluco)mannanase (PCO3)	3.2.1.4 3.2.1.-	Phaedon cochleariae	CCJ09451.1	K4QDG4		1
endo-β-1,4-glucanase; (gluco)mannanase (PCO4)	3.2.1.4 3.2.1.-	Phaedon cochleariae	CCJ09452.1	K7DWA1		1
endo-β-1,4-glucanase; (gluco)mannanase (PCO5)	3.2.1.-	Phaedon cochleariae	CCJ09453.1	K7DW99		1
endo-β-1,4-glucanase; (gluco)mannanase (PCO6)	3.2.1.-	Phaedon cochleariae	CCJ09454.1	K7DWA7		1
Gh45-8		Phaedon cochleariae	CCJ09456.1			1
PHAECO_ LOCUS 10557		Phaedon cochleariae	CAG9822977.1			1
PHAECO_ LOCUS 5678		Phaedon cochleariae	CAG9818178.1			1
PHAECO_ LOCUS 5628		Phaedon cochleariae	CAG9818176.1			1
PHAECO_ LOCUS 5710		Phaedon cochleariae	CAH1154983.1			1
PHAECO_ LOCUS 6825		Phaedon cochleariae	CAH1156029.1			1
PHAECO_ LOCUS 6051		Phaedon cochleariae	CAH1156032.1			1
PHAECO_ LOCUS 6174		Phaedon cochleariae	CAH1156030.1			1
5511		Phaeoacremonium aleophilum UCRPA7 (Phaal1)				1
681059		Phaeosphaeria sp. MPI-PUGE-AT-0046c (Phapo1)				1
613815		Phaeosphaeria sp. MPI-PUGE-AT-0046c (Phapo1)				1
619411		Phaeosphaeria sp. MPI-PUGE-AT-0046c (Phapo1)				1
cellulase (Ghf45eg-1) (fragment)	3.2.1.4	Phaeosphaeria sp. LH21	AGU16531.1	T1WGL7		1
cellulase (Ghf45eg-2)	3.2.1.4	Phaeosphaeria sp. LH21	AGU16532.1	T1WFT4		1
3159520		Phakopsora pachyrhizi K8108 v2.0 (PhapaK8108)				4
4582994		Phakopsora pachyrhizi MG2006 v1.0 (Phapa1)				4
1575194		Phakopsora pachyrhizi PPUFV02 v2.1 (PpacPPUFV02)				4
endoglucanase V (EGV;PcCel45A) (Cel45A)	3.2.1.4	Phanerochaete chrysosporium K-3	BAG68300.1 AEK06231.1	B3Y002 G0ZPJ6	3X2G[A] 3X2H[A] 3X2I[A] 3X2J[A] 3X2K[A] 3X2L[A] 3X2M[A] 3X2N[A] 3X2O[A] 3X2P[A] 4ZM7[A] 5KJO[A] 5KJQ[A]	3
3004240		Phanerochaete chrysosporium RP-78 v2.2 (Phchr2)				3
2980868		Phanerochaete chrysosporium RP-78 v2.2 (Phchr2)				4
545501		Phascolomyces articulosus v1.0 (Phaart1)				1
136903		Phascolomyces articulosus v1.0 (Phaart1)				1
1874009		Phellopilus nigrolimitatus SigPhenig9 v1.0 (Pheni1)				4
1840243		Phellopilus nigrolimitatus SigPhenig9 v1.0 (Pheni1)				3
540480		Phialocephala scopiformis 5WS22E1 v1.0 (Phisc1)				1
771897		Phialocephala scopiformis 5WS22E1 v1.0 (Phisc1)				2
endo-β-1,4-glucanase (EgGH45)		Phialophora sp. G5 / CGMCC 3328	ADZ99360.1			1
143832		Phlebia brevispora HHB-7030 SS6 v1.0 (Phlbr1)				3
147203		Phlebia brevispora HHB-7030 SS6 v1.0 (Phlbr1)				4
125401		Phlebia brevispora HHB-7030 SS6 v1.0 (Phlbr1)				3
26949		Phlebia brevispora HHB-7030 SS6 v1.0 (Phlbr1)				3
124737		Phlebiopsis gigantea (Phlgi1)				3
92552		Phlebiopsis gigantea (Phlgi1)				4
1852995		Phlebopus sp. FC_14 v2.0 (PhlFC14_2)				4
7084115		Cortinarius glaucopus AT 2004 276 v2.0 (Corgl3)				4
6814230		Cortinarius glaucopus AT 2004 276 v2.0 (Corgl3)				3
1656182		Pholiota alnicola AH 47727 v1.0 (Phoaln1)				3
358558		Pholiota alnicola AH 47727 v1.0 (Phoaln1)				3
1648557		Pholiota alnicola AH 47727 v1.0 (Phoaln1)				4
875483		Pholiota conissans CIRM-BRFM 674 v1.0 (Phocon1)				4
992620		Pholiota conissans CIRM-BRFM 674 v1.0 (Phocon1)				3
1037859		Pholiota highlandensis v1.0 (Phohig1)				3
946662		Pholiota highlandensis v1.0 (Phohig1)				4
498786		Plenodomus tracheiphilus IPT5 v1 (Photr1)				1
515760		Plenodomus tracheiphilus IPT5 v1 (Photr1)				1
157012		Phycomyces blakesleeanus NRRL1555 v2 (Phybl2)				1
endo-β-1,4-glucanase (Pce1)	3.2.1.4	Phycomyces nitens FERM P-17447	BAD77808.1 ABA29993.1 ACK18403.1	Q5R230		1
745929		Phycomyces nitens S608 v1.0 (PnitS608_1)				1
glycoside hydrolase family 45, partial (Gh45) (fragment)		Phyllosticta alcides	AHW52296.1			1
353576		Phyllosticta capitalensis CBS 128856 v1.0 (Phycap1)				1
309142		Phyllosticta capitalensis CBS 128856 v1.0 (Phycap1)				3
101626		Phyllosticta citriasiana CBS 120486 v1.0(Phycit1)				1
415564		Phyllosticta citriasiana CBS 120486 v1.0(Phycit1)				3
219673		Phyllosticta citribraziliensis CBS 100098 v1.0 (Phcit1)				1
229889		Phyllosticta citribraziliensis CBS 100098 v1.0 (Phcit1)				3
589037		Phyllosticta citricarpa CBS 127454 v1.0 (Phycitr1)				1
602705		Phyllosticta citricarpa CBS 127454 v1.0 (Phycitr1)				3
441834		Phyllosticta citrichinaensis CBS 129764 v1.0 (Pcit129764)				3
376622		Phyllosticta citrichinaensis CBS 129764 v1.0 (Pcit129764)				1
262154		Phyllosticta citrichinaensis CBS 130529 v1.0 (Phcitr1)				3
207205		Phyllosticta citrichinaensis CBS 130529 v1.0 (Phcitr1)				1
367864		Phyllosticta paracitricarpa CBS 141357 v1.0 (Phy27169)				3
361901		Phyllosticta paracitricarpa CBS 141357 v1.0 (Phy27169)				1
492327		Phyllosticta sp. CPC 27913 v1.0 (Phycpc1)				1
448711		Phyllosticta sp. CPC 27913 v1.0 (Phycpc1)				3
PHYEVI_ LOCUS 8816		Phyllotreta striolata	CAG9862503.1			1
PHYEVI_ LOCUS 8818		Phyllotreta striolata	CAG9862505.1			1
PHYEVI_ LOCUS 8817		Phyllotreta striolata	CAG9862504.1			1
PHYEVI_ LOCUS 6664		Phyllotreta striolata	CAG9860309.1			1
PHYEVI_ LOCUS 6665		Phyllotreta striolata	CAG9860310.1			1
PHYEVI_ LOCUS 4522		Phyllotreta striolata	CAG9858131.1			1
PHYEVI_ LOCUS 3321		Phyllotreta striolata	CAG9856910.1			1
PHYEVI_ LOCUS 2056		Phyllotreta striolata	CAG9855610.1			1
PHYEVI_ LOCUS 2055		Phyllotreta striolata	CAG9855609.1			1
PHYEVI_ LOCUS 31		Phyllotreta striolata	CAG9853556.1			1
40019		Pichia pastoris GS115 (Picpa1)				1
431646		Pilaira anomala RSA1997 v1.0 (Pilano1)				1
435671		Pilaira anomala RSA1997 v1.0 (Pilano1)				1
796051		Pilobolus umbonatus NRRL 6349 v1.0 (Pilumb1)				1
73328		Piriformospora indica DSM 11827 (Pirin1)				4
77104		Piriformospora indica DSM 11827 (Pirin1)				1
582545		Piromyces finnis v3.0 (Pirfi3)				1
182494		Piromyces finnis v3.0 (Pirfi3)
179691		Piromyces finnis v3.0 (Pirfi3)				1
333203		Piromyces finnis v3.0 (Pirfi3)				1
345066		Piromyces finnis v3.0 (Pirfi3)				1
334117		Piromyces finnis v3.0 (Pirfi3)				1
582544		Piromyces finnis v3.0 (Pirfi3)				1
349339		Piromyces finnis v3.0 (Pirfi3)				1
588466		Piromyces finnis v3.0 (Pirfi3)				1
583350		Piromyces finnis v3.0 (Pirfi3)
375533		Piromyces finnis v3.0 (Pirfi3)				1
582546		Piromyces finnis v3.0 (Pirfi3)				1
343522		Piromyces finnis v3.0 (Pirfi3)				1
585671		Piromyces finnis v3.0 (Pirfi3)				1
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