Glycoside Hydrolase Family 45

Activities in Family	Glucomannan-specific endo-β-1,4-glucanase (EC 3.2.1.-); Xyloglucan-specific endo-β-1,4-glucanase / endo-xyloglucanase (EC 3.2.1.151); Endo-β-1,4-glucanase (EC 3.2.1.4);
Mechanism	Inverting e
3D Structure Status	6-stranded β-barrel
Catalytic Nucleophile/Base	Asp (experimental)
Catalytic Proton Donor	Asp (experimental).
Note	formerly known as cellulase family K; distantly related to plant expansins
External resources	CAZypedia; Expansin; PROSITE;
Statistics	GenBank accession (692); Uniprot accession (102); PDB accession (34); 3D entries (10); cryst (0)

Summary

Download GH45 (2249) Taxonomic display Structure (10) Characterized (97)

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Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
6375		Neosartorya fischeri NRRL 181 (Neofi1)				2
508136		Neurospora crassa clade B FGSC 4830 v1.0 (Neucr4830_1)				1
9486		Neurospora crassa trp3 resequencing (Neucr_trp3_1)				1
endoglucanase (NcCel45A;NCU05121.1) (Cel45A)	3.2.1.4	Neurospora crassa OR74A	CAD70529.1 EAA27871.1 XP_324478.1	Q1K5M0 Q872Q1	6MVI[A] 6MVJ[A]	1
9486		Neurospora crassa (Neucr2)				1
134643		Neurospora hispaniola FGSC 10403 v1.0 (Neuhi1)				1
73814		Neurospora tetrasperma FGSC 2509 mat a v1.0 (Neute_mat_a1)				1
443946		Gelasinospora tetrasperma v1.0 (Gelte1)				1
unnamed protein product (fragment)		Nigrospora sp. EP1683860	CAL49905.1			1
773627		Obba rivulosa 3A-2 v1 (Obbri1)				4
834143		Obba rivulosa 3A-2 v1 (Obbri1)				3
753033		Obba rivulosa 3A-2 v1 (Obbri1)				3
55320		Oidiodendron maius Zn (Oidma1)
43493		Oidiodendron maius Zn (Oidma1)				2
43696		Oidiodendron maius Zn (Oidma1)				1
175000		Oidiodendron maius Zn (Oidma1)				2
835508		Oliveonia pauxilla KC1149 v1.0 (Olipa1)				1
269709		Oliveonia pauxilla KC1149 v1.0 (Olipa1)				1
681004		Oliveonia pauxilla KC1149 v1.0 (Olipa1)				4
753170		Oliveonia pauxilla KC1149 v1.0 (Olipa1)				1
708045		Oliveonia pauxilla KC1149 v1.0 (Olipa1)				1
802440		Oliveonia pauxilla KC1149 v1.0 (Olipa1)				1
8105		Omphalotus olearius (Ompol1)				1
7018		Omphalotus olearius (Ompol1)				3
7461		Omphalotus olearius (Ompol1)				4
endo-β-1,4-glucanase II (EGaseII;Oα-EGaseII)		Oncideres albomarginata chamela	ADI24132.1			1
285199		Ophiobolus disseminans CBS 113818 v1 (Ophdi1)				1
305111		Ophiobolus disseminans CBS 113818 v1 (Ophdi1)				1
1981337		Ophiostoma novo-ulmi subsp. novo-ulmi H327 (Ophnu1)
1980632		Ophiostoma novo-ulmi subsp. novo-ulmi H327 (Ophnu1)				1
EGX51951.1		Orbilia oligospora ATCC 24927	EGX51951.1			1
EGX47022.1		Orbilia oligospora ATCC 24927	EGX47022.1			1
EGX43975.1		Orbilia oligospora ATCC 24927	EGX43975.1			1
EGX43933.1		Orbilia oligospora ATCC 24927	EGX43933.1			1
1178149		Orpinomyces sp. (Orpsp1_1)
1190390		Orpinomyces sp. (Orpsp1_1)				1
1181003		Orpinomyces sp. (Orpsp1_1)
1183643		Orpinomyces sp. (Orpsp1_1)				1
1174556		Orpinomyces sp. (Orpsp1_1)				1
1187037		Orpinomyces sp. (Orpsp1_1)
1178425		Orpinomyces sp. (Orpsp1_1)				1
1176284		Orpinomyces sp. (Orpsp1_1)				1
1181857		Orpinomyces sp. (Orpsp1_1)				1
1181902		Orpinomyces sp. (Orpsp1_1)				1
1179810		Orpinomyces sp. (Orpsp1_1)				1
1183362		Orpinomyces sp. (Orpsp1_1)				1
1180594		Orpinomyces sp. (Orpsp1_1)				1
1175781		Orpinomyces sp. (Orpsp1_1)				1
1186105		Orpinomyces sp. (Orpsp1_1)				1
1178591		Orpinomyces sp. (Orpsp1_1)				1
1429303		Oudemansiella mucida CBS 558.79 v1.0 (Oudmuc1)				4
1531768		Oudemansiella mucida CBS 558.79 v1.0 (Oudmuc1)				1
1280405		Oudemansiella mucida CBS 558.79 v1.0 (Oudmuc1)				1
1373701		Oudemansiella mucida CBS 558.79 v1.0 (Oudmuc1)				1
1412889		Panaeolus papilionaceus CIRM-BRFM 715 v1.0 (Panpap1)				3
1455641		Panaeolus papilionaceus CIRM-BRFM 715 v1.0 (Panpap1)				4
1260793		Paraconiothyrium sporulosum AP3s5-JAC2a v1 (Parsp1)				3
1247394		Paraconiothyrium sporulosum AP3s5-JAC2a v1 (Parsp1)				1
268278		Paraconiothyrium sporulosum AP3s5-JAC2a v1 (Parsp1)				1
464355		Paraphoma chrysanthemicola MPI-GEGE-AT-0034 v1.0 (Parch1)				1
310188		Paraphoma chrysanthemicola MPI-GEGE-AT-0034 v1.0 (Parch1)				1
562786		Paraphoma chrysanthemicola MPI-GEGE-AT-0034 v1.0 (Parch1)				1
286884		Paraphoma chrysanthemicola MPI-SDFR-AT-0120 v1.0 (Parchr1)				1
69500		Paraphoma chrysanthemicola MPI-SDFR-AT-0120 v1.0 (Parchr1)				1
445004		Paraphoma chrysanthemicola MPI-SDFR-AT-0120 v1.0 (Parchr1)				1
glycoside hydrolase family 45, partial (Gh45) (fragment)		Paraphoma sp. Z-1	AHW52294.1			1
420144		Parasitella parasitica v1.0 (Parpar1)				1
JI435_133620		Parastagonospora nodorum SN15	QRD05934.1			1
JI435_077880		Parastagonospora nodorum SN15	QRC94555.1			1
JI435_113030		Parastagonospora nodorum SN15	QRD02548.1			1
637213		Thielavia appendiculata CBS 731.68 v1 (Thiap1)				1
629289		Thielavia appendiculata CBS 731.68 v1 (Thiap1)				1
518044		Thielavia hyrcaniae CBS 757.83 v1 (Thihy1)				1
506802		Thielavia hyrcaniae CBS 757.83 v1 (Thihy1)				1
999729		Patellaria atrata (Patat1)				1
934036		Patellaria atrata (Patat1)				1
ORF (fragment)		Patellina sp. P10-1	AHW52300.1			1
ORF (fragment)		Patellina sp. P10-1	AHW52301.1			1
327831		Paxillus rubicundulus Ve08.2h10 v2.0 (Paxru2)				4
endoglucanase V / 45A (EG V;PdCel45A) (Cel45A)	3.2.1.4	Penicillium decumbens 114-2	ACF33814.1	B5AKD1		2
7898		Penicillium oxalicum 114-2 (Penox1)				2
endoglucanase 3 (Egl3)		Penicillium oxalicum GZ-2	AGW24295.1			2
2604		Penicillium subrubescens (Pensub1)				2
694007		Peniophora sp. v1.0 (Ricme1)				3
681936		Peniophora sp. v1.0 (Ricme1)				3
682009		Peniophora sp. v1.0 (Ricme1)				4
671461		Peniophora sp. v1.0 (Ricme1)				3
ORF (fragment)		Pestalotia aceris	AHW52280.1			1
13389		Pestalotiopsis fici W106-1 (Pesfi1)				1
6245		Pestalotiopsis fici W106-1 (Pesfi1)				1
ORF (fragment)		Pestalotiopsis glandicola	AHW52311.1			1
ORF (fragment)		Pestalotiopsis glandicola	AHW52312.1			1
ORF (fragment)		Pestalotiopsis guepinii	AHW52308.1			1
ORF (fragment)		Pestalotiopsis sp. L4-1	AHW52275.1			1
ORF (fragment)		Pestalotiopsis sp. L4-1	AHW52276.1			1
519300		Pestalotiopsis sp. NC0098 v1.0 (Pestal1)				1
586015		Pestalotiopsis sp. NC0098 v1.0 (Pestal1)
462071		Pestalotiopsis sp. NC0098 v1.0 (Pestal1)				1
endo-β-1,4-glucanase (EG)	3.2.1.4	Phaedon cochleariae	CAA76931.1	O97401		1
endo-β-1,4-glucanase (PCO1)	3.2.1.4	Phaedon cochleariae	CCJ09450.1	K4QDH6		1
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