Activities in Sub Family	[retaining] 4-α-glucanotransferase / amylomaltase (EC 2.4.1.25); [retaining] α-amylase (EC 3.2.1.1);
Mechanism	Retaining a
Clan	GH-H
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Asp (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	New: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resources	CAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)	MEGAZYME; PROZOMIX;
Statistics	GenBank accession (1); Uniprot accession (64); PDB accession (6); 3D entries (2); cryst (0)

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Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
ORF		Musca domestica ALHF	AFP59260.1			15
ORF		Musca domestica ALHF	AFP63859.1 AFP63954.1			15
ORF (fragment)		Musca domestica ALHF	AFP61218.1			15
ORF (fragment)		Musca domestica ALHF	AFP62307.1			15
Amyrel (fragment)		Mycodrosophila sp. JLDL-2005	AAW66448.1			15
NTJ_13849		Nesidiocoris tenuis Japan	BET01034.1			15
NTJ_13852 (fragment)		Nesidiocoris tenuis Japan	BET01035.1			15
NTJ_13851		Nesidiocoris tenuis Japan	BET01036.1			15
NTJ_13850		Nesidiocoris tenuis Japan	BET01033.1			15
NTJ_09388		Nesidiocoris tenuis Japan	BES96577.1			15
NTJ_09389		Nesidiocoris tenuis Japan	BES96576.1			15
NTJ_09390		Nesidiocoris tenuis Japan	BES96578.1			15
NTJ_09391 (fragment)		Nesidiocoris tenuis Japan	BES96579.1			15
NTJ_11959		Nesidiocoris tenuis Japan	BES99142.1			15
NEZAVI_ LOCUS 7558		Nezara viridula	CAH1397787.1			15
Q1695_003707		Nippostrongylus brasiliensis MIMR	WKY12336.1			15
Q1695_003706 (fragment)		Nippostrongylus brasiliensis MIMR	WKY12334.1			15
α-amylase		Odoiporus longicollis	AHN92452.2			15
ORF		Oryctes rhinoceros	QEI22884.1			15
α-amylase (Amy)		Ostrinia nubilalis	AAA03715.1 AAA03640.1 AAA03641.1 AAA03707.1			15
α-amylase (Amy) (fragment)		Patella vulgata	ACA34388.1 AAO17925.1			15
amylase (fragment)		Penaeus vannamei	AIJ02082.1			15
α-amylase		Periplaneta americana	AKH04310.1			15
α-amylase (fragment)		Periplaneta americana	ACA34371.1			15
ORF (fragment)		Periplaneta americana	AIA09344.1 AVA17418.1 AVA17420.1			15
α-amylase		Phaedon cochleariae	CAA76926.1			15
PHAECO_ LOCUS 81		Phaedon cochleariae	CAH1116249.1			15
ORF (fragment)		Phlebotomus arabicus	ACS93490.1			15
salivary α-amylase (fragment)		Phlebotomus orientalis Melka Werer	AGT96462.1			15
Amy / PPTAMY		Phlebotomus papatasi	AGE83100.1			15
Amyrel (fragment)		Phorticella singularis	ADA77344.1			15
Amyrel (fragment)		Phorticella sp. K1 AY-2009	ADA77345.1			15
PHYEVI_ LOCUS 7492		Phyllotreta striolata	CAG9861149.1			15
PHYEVI_ LOCUS 3702		Phyllotreta striolata	CAG9857297.1			15
WS02763_C20		Picea sitchensis	ABR17025.1			15
α-amylase (Amy) (fragment)		Pipunculidae sp. FM-2005	AAY88848.1			15
PSYICH_ LOCUS 10094		Psylliodes chrysocephala	CAH1109805.1			15
PSYICH_ LOCUS 12568 (fragment)		Psylliodes chrysocephala	CAH1112073.1			15
PSYICH_ LOCUS 12704		Psylliodes chrysocephala	CAH1112072.1			15
α-amylase		Pteromalus puparum	QAV56505.1			15
α-amylase		Pteromalus puparum	QAV56504.1			15
α-amylase		Pteromalus puparum	QAV56506.1			15
α-amylase (KME1)		Reticulitermes speratus	AGJ52072.1			15
α-amylase		Rhodnius prolixus	JAA77077.1			15
AmyreL (fragment)		Samoaia leonensis	ABW06945.1			15
α-amylase (Amy) (fragment)		Sarcophaga carnaria	AAY88849.1			15
Amyrel (fragment)		Scaptodrosophila bryani	AAW83127.1			15
Amyrel (fragment)		Scaptodrosophila coracina	ADA77351.1			15
Amyrel		Scaptodrosophila finitima	AAW66432.1			15
Amyrel (fragment)		Scaptodrosophila latifasciaeformis	ADA77343.1			15
Amy (fragment)		Scaptodrosophila latifasciaeformis	AAQ13458.1			15
α-amylase (Amy1)		Scaptodrosophila lebanonensis 11010-0021.0	BAC06340.1			15
Amyrel		Scaptomyza pallida	AAW66447.1			15
α-amylase (Amy) (fragment)		Scathophagidae sp. FM-2005a	AAY88850.1			15
α-amylase (Amy) (fragment)		Scathophagidae sp. FM-2005c	AAY88851.1			15
α-amylase (Amy;SiAmy)		Scirpophaga incertulas	ABV24963.1			15
salivary amylase		Sergentomyia schwetzi	QHO60735.1			15
salivary amylase		Sergentomyia schwetzi	QHO60734.1			15
salivary amylase		Sergentomyia schwetzi	QHO60736.1			15
salivary α-amylase (fragment)		Simulium guianense	AEB96562.1			15
salivary α-amylase		Simulium nigrimanum	ACZ28190.1			15
salivary α-amylase		Simulium nigrimanum	ACZ28191.1			15
α-amylase (Amy1)		Sitophilus oryzae	ADM73187.1 ADN06265.1			15
α-amylase (Amy) (fragment)		Sphaeroceridae sp. Cypselidae FM-2005	AAY88837.1			15
SPEXI_ LOCUS 5555		Spodoptera exigua	CAH0695809.1			15
SPEXI_ LOCUS 3423 (fragment)		Spodoptera exigua	CAH0691731.1			15
SPEXI_ LOCUS 3423 (fragment)		Spodoptera exigua	CAH0691731.1			15
SPEXI_ LOCUS 3423 (fragment)		Spodoptera exigua	CAH0691731.1			15
α-amylase (Amy2)		Spodoptera frugiperda	AAO13754.1			15
SPLIT_ LOCUS 3456		Spodoptera littoralis	CAH1638098.1			15
SPLIT_ LOCUS 3457		Spodoptera littoralis	CAH1638099.1			15
SPLIT_ LOCUS 3458		Spodoptera littoralis	CAH1638100.1			15
SPLIT_ LOCUS 5562		Spodoptera littoralis	CAH1640206.1			15
SRAE_2000360100		Strongyloides ratti ED321 Heterogonic	CEF68947.1			15
α-amylase (Amy) (fragment)		Syrphidae sp. FM-2005a	AAY88854.1			15
α-amylase (Amy) (fragment)		Syrphidae sp. FM-2005b	AAY88855.1			15
α-amylase (Amy) (fragment)		Syrphidae sp. FM-2005c	AAY88856.1			15
α-amylase (Amy) (fragment)		Syrphidae sp. FM-2005d	AAY88857.1			15
α-amylase	3.2.1.1	Tenebrio molitor		P56634	1CLV[A] 1JAE[A] 1TMQ[A] 1VIW[A]	15
α-amylase (Amy) (fragment)		Tetanocera ferruginea	AAY88852.1			15
α-amylase (Amy) (fragment)		Tetanocera ferruginea	AAY88853.1			15
α-amylase (Amy) (fragment)		Thaumatomyia notata	AAY88858.1			15
α-amylase (Amy) (fragment)		Thaumatomyia notata	AAY88859.1			15
TDIB3V08_LOCUS11437 (fragment)		Timema douglasi	CAD7205285.1			15
TDIB3V08_LOCUS11077 (fragment)		Timema douglasi	CAD7204921.1			15
TDIB3V08_LOCUS13077 (fragment)		Timema douglasi	CAD7206928.1			15
TDIB3V08_LOCUS13037 (fragment)		Timema douglasi	CAD7206888.1			15
TDIB3V08_LOCUS11708 (fragment)		Timema douglasi	CAD7205557.1			15
TSIB3V08_LOCUS11370 (fragment)		Timema shepardi	CAD7267363.1			15
TSIB3V08_LOCUS12528 (fragment)		Timema shepardi	CAD7268526.1			15
α-amylase		Tribolium castaneum	CAA30009.1 AFO37738.1			15
α-amylase I	3.2.1.1	Tribolium castaneum	AAA03708.1 AGW27504.1 AGW27506.1	Q26854 U3N7E6 U3NE54		15
α-amylase II	3.2.1.1	Tribolium castaneum	AAA03709.1	Q26855		15
α-amylase		Tribolium castaneum	AGW27505.1			15
α-amylase	3.2.1.1	Zabrotes subfasciatus	AAF73435.1	Q9N2P9		15
Amyrel		Zaprionus badyi	AAW66421.1			15
AmyreL		Zaprionus beninensis	ABO60917.1			15
Amyrel		Zaprionus bogoriensis	AAW66422.1			15
AmyreL		Zaprionus camerounensis	ABO60918.1			15
Amyrel (fragment)		Zaprionus campestris	ADA77352.1			15
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