Glycoside Hydrolase Family 13 / Subf 15

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Activities in Sub Family
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (984); Uniprot accession (380); PDB accession (4); 3D entries (1); cryst (0)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
Eukaryota
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 α-amylase (Amy) (fragment)   Drosophila microlabis AAN16145.1     15
 amylase-related protein (Amyrel) (fragment)   Drosophila microlabis AAN16169.1     15
 putative amylase (fragment)   Drosophila microlabis AAC47362.1 Q24102   15
 Amyrel   Drosophila mimetica AAW64461.1     15
 Amyrel (fragment)   Drosophila mimica AAW66442.1     15
 putative amylase (fragment)   Drosophila miranda BAA22494.1
BAA22495.1
O15960
O15961
  15
 amylase distal, partial (Amy-D) (fragment)   Drosophila mitchelli AFM76794.1     15
 Amy (fragment)   Drosophila mojavensis AAQ13451.1 Q5NKX6   15
 Amyrel   Drosophila monieri AAL99576.1 Q8T7X9   15
 Amyrel   Drosophila nagarholensis AAL99578.1 Q8T7X7   15
 amylase (fragment)   Drosophila nagarholensis INDIA BAB39188.1 Q8IAG6   15
 amylase (fragment)   Drosophila nagarholensis INDIA BAB39187.1 Q8IAG7   15
 α-amylase (Amy 1)   Drosophila nagarholensis PGE BAC06331.1 Q8MY55   15
 α-amylase (Amy 2)   Drosophila nagarholensis PGE BAC06332.1 Q8MY54   15
 α-amylase (Amy 3)   Drosophila nagarholensis PGE BAC06333.1 Q8MY53   15
 alpha amylase-related-protein, partial (AmyreL) (fragment)   Drosophila nannoptera 15090-1692.10 AHL43638.1     15
 alpha amylase, partial (fragment)   Drosophila nannoptera 15090-1692.10 AHL43652.1     15
 α-amylase (Amy) (fragment)   Drosophila narragansett AAN16200.1     15
 Amyrel   Drosophila nasuta AAW64462.1     15
 amyrel protein, partial (fragment)   Drosophila nasuta ADM3 BAR88683.1
BAR88684.1
BAR88685.1
BAR88686.1
BAR88687.1
BAR88688.1
BAR88689.1
BAR88690.1
BAR88691.1
BAR88692.1
BAR88693.1
BAR88694.1
BAR88695.1
BAR88696.1
BAR88697.1
BAR88698.1
    15
 amylase   Drosophila nasuta IND_DN_U11 ANZ79224.1     15
 Amyrel   Drosophila nebulosa AAW64463.1     15
 Amyrel   Drosophila neocordata AAW66386.1     15
 α-amylase-related protein (AmyreL)   Drosophila neohypocausta AUT31441.1     15
 Amyrel   Drosophila neomorpha AAW66387.1     15
 Amy (fragment)   Drosophila nigrodumosa AAQ13452.1 Q5NKX5   15
 Amyrel   Drosophila nigrodumosa AAW66388.1     15
 Amyrel   Drosophila nigromaculata AAW66389.1     15
 Amyrel (fragment)   Drosophila nigromelanica AEQ63844.1     15
 Amyrel   Drosophila nikananu AAL99396.1 Q8T7W4   15
 α-amylase (fragment)   Drosophila nikananu AAM69529.1 Q8MX59   15
 α-amylase (fragment)   Drosophila nikananu AAM69530.1 Q8MX58   15
 α-amylase (fragment)   Drosophila nikananu AAM69531.1 Q8MX57   15
 amylase (fragment)   Drosophila nikananu INDIA14028.0601.0 BAB39189.1 Q8IAG5   15
 Amyrel   Drosophila novamexicana AAW66390.1     15
 amylase-related protein (Amyrel) (fragment)   Drosophila obscura AAN16194.1     15
 α-amylase (Amy) (fragment)   Drosophila obscura SPIER AAN16146.1     15
 Amyrel   Drosophila ochrogaster AAW66391.1     15
 Amy (fragment)   Drosophila ogumai AEM77103.1     15
 AmyreL (fragment)   Drosophila ogumai AEM77120.1     15
 Amy (fragment)   Drosophila ohnishii AEM77102.1     15
 AmyreL (fragment)   Drosophila ohnishii AEM77121.1     15
 α-amylase-like   Drosophila orena AAC39108.2
AAC39108.1
O77015   15
 Amy   Drosophila orena BAA04666.1
BAA04667.1
Q24610
Q24611
  15
 amylase (fragment)   Drosophila orosa INDIA14028.0611.0 BAB39190.1 Q8IAG4   15
 alpha amylase-related-protein, partial (AmyreL) (fragment)   Drosophila pachea 15090-1698.02 AHL43639.1     15
 alpha amylase, partial (fragment)   Drosophila pachea 15090-1698.02 AHL43653.1     15
 Amyrel   Drosophila pallidifrons AAW66392.1     15
 Amyrel   Drosophila pallidipennis AAW66393.1     15
 Amyrel   Drosophila pallidosa AAF25713.1 Q9NJN9   15
 Amyrel (fragment)   Drosophila palustris AAW66443.1     15
 Amy (fragment)   Drosophila parabipectinata AEM77108.1     15
 Amyrel   Drosophila parabipectinata AAW66395.1     15
 AmyreL (fragment)   Drosophila parvula AEM77122.1     15
 amylase (fragment)   Drosophila parvula CNX312 BAB39191.1 Q8IAG3   15
 Amyrel   Drosophila pavani AAW66396.1     15
 α-amylase (Amy) (fragment)   Drosophila persimilis AAN16151.1     15
 amylase-related protein (Amyrel) (fragment)   Drosophila persimilis AAN16165.1     15
 putative amylase (fragment)   Drosophila persimilis BAA22496.1
BAA22497.1
O15962
O15963
  15
 Amyrel   Drosophila phaeopleura AAW66397.1     15
 Amyrel   Drosophila phalerata AAW66398.1     15
 Amyrel   Drosophila polychaeta AAW66400.1     15
 Amyrel   Drosophila polymorpha AAW66401.1     15
 Amy (fragment)   Drosophila prolongata AEM77094.1     15
 AmyreL (fragment)   Drosophila prolongata AEM77123.1     15
 Amy (fragment)   Drosophila prostipennis AEM77099.1     15
 AmyreL (fragment)   Drosophila prostipennis AEM77124.1     15
 Amyrel   Drosophila pruinosa AAW83126.1     15
 AmyreL (fragment)   Drosophila pseudoananassae AEM77125.1     15
 Amyrel   Drosophila pseudoananassae nigrens AAW66403.1     15
 Amy (fragment)   Drosophila pseudoananassae POM441 BAA22498.1
BAA22499.1
O18665   15
 Amyrel (fragment)   Drosophila pseudoananassae pseudoananassae AAW66404.1     15
 α-amylase 3.2.1.1 Drosophila pseudoobscura AAC46839.1
AAA73568.1
AAA73569.1
AAA73570.1
AAA73571.1
AAC46840.1
AAC46841.1
AAC46842.1
AEM77093.1
CAA53819.1
CAA53820.1
CAA53821.1
O46116
Q24609
Q24613
Q27609
Q27610
Q27611
Q27612
Q27863
Q27891
  15
 Amyrel   Drosophila pseudoobscura AAC48346.2
AAC48346.1
O18552   15
 AmyreL (fragment)   Drosophila pseudoobscura AEM77110.1     15
 AMYREL (Amyrel) (fragment)   Drosophila pseudoobscura bogotana AAN16201.1     15
 Amyrel   Drosophila pseudotakahashii AAW66405.1     15
 alpha amylase-related-protein, partial (AmyreL) (fragment)   Drosophila pseudotalamancana 15040-1191.01 AHL43641.1     15
 alpha amylase, partial (fragment)   Drosophila pseudotalamancana 15040-1191.01 AHL43655.1     15
 Amy (fragment)   Drosophila pulchrella AEM77095.1     15
 AmyreL (fragment)   Drosophila pulchrella AEM77126.1     15
 α-amylase (fragment)   Drosophila punjabiensis AAM69532.1 Q8MX56   15
 α-amylase (fragment)   Drosophila punjabiensis AAM69533.1 Q8MX55   15
 α-amylase (fragment)   Drosophila punjabiensis AAM69536.1 Q8MX52   15
 α-amylase (fragment)   Drosophila punjabiensis AAM69537.1 Q8MX51   15
 putative amylase   Drosophila punjabiensis AAC39115.1 O77022   15
 α-amylase (Amy 1)   Drosophila punjabiensis 14028-0531.0 BAC06334.1 Q8MY52   15
 α-amylase (Amy 2)   Drosophila punjabiensis 14028-0531.0 BAC06335.1 Q8MY51   15
 α-amylase (Amy 3)   Drosophila punjabiensis 14028-0531.0 BAC06336.1 Q8MY50   15
 Amy2 (fragment)   Drosophila punjabiensis 14028-0641-0 (BOWLING GREEN STOCK CENTER) AAG42568.1     15
 Amy1 (fragment)   Drosophila punjabiensis 14028-0641-0 (BOWLING GREEN STOCK CENTER) AAG42567.1     15
 amylase (fragment)   Drosophila punjabiensis MDL177 BAB39186.1 Q8IAG8   15
 α-amylase (fragment)   Drosophila quadraria 14028-0651-0 (BOWLING GREEN STOCK CENTER) AAG42548.1     15
 amylase (fragment)   Drosophila quadraria NIG BAC53961.1 Q8IAH9   15
 amylase (fragment)   Drosophila quadraria NIG BAC53962.1 Q8IAH8   15
 α-amylase-related protein, partial (AmyreL)   Drosophila quadrilineata AUT31442.1     15
 Amy   Drosophila repleta AAQ13427.1 Q5NKY3   15
 Amyrel   Drosophila repleta AAW66402.1     15
 Amyrel   Drosophila repletoides AAW66406.1     15
 alpha amylase-related-protein, partial (AmyreL) (fragment)   Drosophila robusta 15020-1111.10 AHL43640.1     15
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